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Displaying drugs 601 - 625 of 15617 in total

Sodium tartrate

Sodium tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and odorless crystals. It is obtained as a byproduct of wine manufacturing. Sodium tartrate is generally recognized as safe (GRAS) as a direct human food ingredient. It acts as an emulsifier and pH...
Approved
Matched Description: … It acts as an emulsifier and pH control agent in food products [L2590]. ... tartrate is a disodium salt of l-( + )-tartaric acid that is identified by transparent, colorless, and ... This compound is commonly used as an emulsifier in cheese/cheese spread products and is not to exceed …
Matched Categories: … Alimentary Tract and Metabolism …

L-Lactic acid

Approved
Experimental

Betamethasone phosphate

Betamethasone phosphate is a prodrug that is rapidly hydrolyzed, providing rapidly accessible betamethasone to agonize glucocorticoid receptors. Betamethasone provides greater anti-inflammatory activity than prednisolone with less sodium and water retention. Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.
Approved
Vet approved
Matched Description: … L11994] Betamethasone provides greater anti-inflammatory activity than [prednisolone] with less sodium and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Fezolinetant

Vasomotor symptoms (VMS), more colloquially known as hot flashes or night sweats, are some of the most common symptoms in menopause. With a median duration of 7.4 years, vasomotor symptoms are also the most common reasons why women seek treatments for menopausal issues.[A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms...
Approved
Investigational
Matched Iupac: … 5-[(8R)-7-(4-fluorobenzoyl)-8-methyl-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-3-methyl-1,2,4-thiadiazole …
Matched Description: … severe VMS daily have reported a decline in sleep quality, concentration, sexual activity, energy, and ... [A259606] Estrogen is a potent neuromodulator, particularly in the hypothalamus, and has been shown to ... increase neurokinin B signalling, increasing the activity of KNDy neurons and therefore the activity …
Matched Categories: … Genito Urinary System and Sex Hormones …

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Description: … that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce ... prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. ... the risk of some complications (including pneumonia and respiratory failure). …

Pregabalin

Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other conditions. Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects...
Approved
Investigational
Matched Description: … [A173995] It may be used to manage neuropathic pain, postherpetic neuralgia, and fibromyalgia among other ... [A187190,L7066] Pregabalin is marketed by Pfizer under the trade name Lyrica and Lyrica Cr (extended …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Fluorometholone

A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Approved
Investigational
Matched Description: … A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions …
Matched Categories: … fluorometholone and mydriatics ... fluorometholone and antibiotics ... fluorometholone and antiinfectives ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Tenoxicam

Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain.
Approved
Matched Iupac: … 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide …
Matched Description: … and control acute pain. ... Tenoxicam, an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Levetiracetam

Levetiracetam is a drug within the pyrrolidine class that is used to treat various types of seizures stemming from epileptic disorders. It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs).[L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918]...
Approved
Matched Description: … It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated ... [L8606,L8600,L8615] Levetiracetam possesses a wide therapeutic index[L8615,A185918] and little-to-no ... choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and …

Thyrotropin alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of...
Approved
Vet approved
Matched Description: … similarity with the alpha subunit of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and ... linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Anterior Pituitary Lobe Hormones and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Choriogonadotropin alfa

Recombinant human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER-121, SER-127, SER-132 and SER-138 (on beta subunit). The primary structure of the alpha-chain of r-hCG is identical...
Approved
Matched Description: … O-linked carbohydrate moieties linked to ASN-52 and ASN-78 (on alpha subunit) and ASN-13, ASN-30, SER ... -121, SER-127, SER-132 and SER-138 (on beta subunit). ... human chorionic gonadotropin with 2 subunits, alpha = 92 residues, beta = 145 residues, each with N-and …
Matched Categories: … Gonadotropins and Antigonadotropins ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Kappadione

Kappadione is a Vitamin K derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and marketed by Lilly Marketing for this drug has been discontinued and is not available in North America . It has been found to have carcinogenic potential in mammalian cells as...
Approved
Matched Iupac: … tetrasodium 3-methyl-4-(phosphonatooxy)naphthalen-1-yl phosphate …
Matched Description: … derivative (chemically, it is menadiol sodium diphosphate), previously approved by FDA prior to 1982 and ... marketed by Lilly Marketing for this drug has been discontinued and is not available in North America …

Soybean oil

Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated ... It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. ... triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and …
Matched Mixtures name: … SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Categories: … Diet, Food, and Nutrition …

Disopyramide

A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Approved
Matched Iupac: … 4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide …
Matched Description: … It also possesses some anticholinergic and local anesthetic properties. ... anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and …

Lypressin

Approved
Matched Iupac: … ]pyrrolidin-2-yl](hydroxy)methylidene}amino)-N-[(C-hydroxycarbonimidoyl)methyl]hexanimidic acid ... 13-benzyl-6,9,12,15,18-pentahydroxy-10-[2-(C-hydroxycarbonimidoyl)ethyl]-7-[(C-hydroxycarbonimidoyl)methyl ... ]-16-[(4-hydroxyphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaene-4-carbonyl …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... [A231379] Daptomycin was approved by the FDA on September 12, 2003, and is marketed under the name …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Terlipressin

Terlipressin is a synthetic analogue of vasopressin, which is an endogenous neurohormone that acts as a vasoconstrictor. It is a prodrug of lypressin, or lysine vasopressin. Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for the V1 receptor. As a potent vasopressor, terlipressin has been...
Approved
Investigational
Matched Description: … Compared to endogenous vasopressin, terlipressin has a longer half life and increased selectivity for ... [L43217] As a potent vasopressor, terlipressin has been investigated in various shock states and conditions ... [A2601, A2602, A2603, A2604, A2605] It was also studied in hepatorenal syndrome (HRS) and variceal bleeding …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Vasopressin and Analogues ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Abaloparatide

Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) and an agonist at the parathyroid hormone type 1 (PTH1) receptor. It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and human PTHrP 1-34. Abaloparatide and PTHrP share the first 21 amino acids...
Approved
Investigational
Matched Description: … [L740] Abaloparatide and PTHrP share the first 21 amino acids and the receptor-activating domain. ... Abaloparatide is an N-terminal analog of parathyroid hormone-related protein (PTHrP) [A256778] and an ... [L740] It is a synthetic 34 amino acid peptide with 41% homology to human parathyroid hormone 1-34 and …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Intercellular Signaling Peptides and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Artesunate

Artesunate is indicated for the initial treatment of severe malaria. The World Health Organization recommends artesunate as first line treatment for severe malaria. Artesunate was developed out of a need for a more hydrophilic derivative of artemisinin. Artesunate was granted FDA approval on 26 May 2020.
Approved
Investigational
Matched Categories: … Artemisinin and derivatives ... artesunate and mefloquine ... artesunate and amodiaquine ... artesunate and pyronaridine ... artesunate, sulfalene and pyrimethamine …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved

Halazepam

Halazepam is a benzodiazepine derivative drug exerting anxiolytic, anticonvulsant, sedative, a muscle relaxing effects.[A1212, A178114] It has been shown to be less toxic than chlordiazepoxide or diazepam. This drug is no longer marketed in the United States, and was withdrawn by Schering, its manufacturer, in 2009.[L6226, L6229]
Approved
Illicit
Withdrawn
Matched Iupac: … 7-chloro-5-phenyl-1-(2,2,2-trifluoroethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Description: … [A1212] This drug is no longer marketed in the United States, and was withdrawn by _Schering_, its manufacturer …
Matched Categories: … Benzodiazepines and benzodiazepine derivatives …

Fluspirilene

A long-acting injectable antipsychotic agent used for chronic schizophrenia.
Approved
Investigational
Matched Iupac: … 8-[4,4-bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one …

Isosulfan blue

Approved
Matched Iupac: … 4-{[4-(diethylamino)phenyl](2,5-disulfophenyl)methylidene}-N,N-diethylcyclohexa-2,5-dien-1-iminium …

Eflornithine

Eflornithine is an irreversible ornithine decarboxylase inhibitor originally developed as a treatment for human African trypanosomiasis. Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and cancer, especially when ornithine decarboxylase is highly upregulated in tumor cells.[A4112, A262834] Additionally, ornithine decarboxylase is activated by c-myc or...
Approved
Withdrawn
Matched Description: … [A262839] In 1960 and 2000, the FDA approved eflornithine under the brand names ORNIDYL and VANIQUA ... Further research has also implicated ornithine decarboxylase in other conditions like facial hirsutism and ... under the brand name IWILFIN as an oral maintenance therapy to reduce the risk of relapse in adult and …
Matched Categories: … Skin and Mucous Membrane Agents ... Amino Acids, Peptides, and Proteins ... Agents Against Leishmaniasis and Trypanosomiasis ... Antineoplastic and Immunomodulating Agents ... Antiparasitic Products, Insecticides and Repellents …

Cipaglucosidase alfa

Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. Other types of enzyme replacement therapy for the treatment of Pompe disease include alglucosidase alfa and avalglucosidase alfa. Cipaglucosidase...
Approved
Investigational
Matched Description: … types of enzyme replacement therapy for the treatment of Pompe disease include [alglucosidase alfa] and ... cipaglucosidase alfa be granted marketing authorization for the treatment of Pompe disease,[L45275] and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Displaying drugs 601 - 625 of 15617 in total