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Displaying drugs 626 - 650 of 6142 in total
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. ... [A263833] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment …
Matched Categories: … Alimentary Tract and Metabolism ... Bile and Liver Therapy ... Heterocyclic Compounds, 1-Ring ... Acids, Acyclic ... Carboxylic Acids
An ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Approved
Investigational
Matched International brands: … Tavist-1 ... Allerhist-1
Matched Synonyms: … (+)-(2R)-2-(2-(((R)-p-chloro-α-methyl-α-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine ... (+)-(2R)-2-[2-[[(R)-p-chloro-α-methyl-α-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine …
Matched Iupac: … (2R)-2-{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine …
Matched Description: … ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Tavist Tablets 1mg ... TAVEGYL SURUP, 100 ML ... TAVEGYL 1MG TABLETTEN …
A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules. This pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. This compound has been classified as a loop...
Approved
Investigational
Matched Synonyms: … (2,3-Dichloro-4-(2-methylene-1-oxobutyl)phenoxy)acetic acid ... Etacrinic acid ... Etacrynic acid
Matched Name: … Etacrynic acid
Matched Iupac: … 2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetic acid
Matched Description: … Henle, but also in the proximal and distal tubules. ... A compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of ... This pharmacological action results in excretion of these ions, increased urinary output, and reduction …
Matched Categories: … Acids, Acyclic ... Hydroxy Acids ... Carboxylic Acids ... etacrynic acid ... Aryloxyacetic Acid Derivatives …
Matched Products: … Ethacrynic Acid ... Ethacrynic acid
A beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and an antiglaucoma agent.
Approved
Matched Iupac: … 5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … beta-adrenergic antagonist used as an anti-arrhythmia agent, an anti-angina agent, an antihypertensive agent, and
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … CARTEOL LP %1 UZUN ETKILI GOZ DAMLASI, 3 ML ... CARTEOL LP %2 UZUN ETKILI GOZ DAMLASI, 3 ML …
Experimental
Matched Synonyms: … 3-ketobutanoic acid ... 3-Ketobutyric acid ... 3-Oxobutyric acid
Matched Name: … Acetoacetic acid
Matched Iupac: … 3-oxobutanoic acid
Matched Categories: … Keto Acids ... Carboxylic Acids
Difenoxin is a 4-phenylpiperidine which is closely related to the opioid analgesic meperidine. Difenoxin alone is a USA Schedule I controlled drug, as it may be habit forming. However, it is listed as a Schedule IV controlled drug if combined with atropine, which is added to decrease deliberate misuse. Motofen(R)...
Approved
Illicit
Matched Synonyms: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotic acid ... Diphenoxilic acid ... Diphenoxylic acid
Matched Iupac: … 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
Matched Description: … It is approved by the FDA to treat acute and chronic diarrhea. ... Motofen(R) is a brand mixture which combines atropine sulfate and difenoxin hydrochloride. ... It works mostly in the periphery and activates opioid receptors in the intestine rather than the central …
Matched Salts cas: … 35607-36-4 …
Matched Categories: … Alimentary Tract and Metabolism ... Heterocyclic Compounds, 1-Ring ... Acids, Heterocyclic ... Isonipecotic Acids
Investigational
Matched Synonyms: … Phosphonic acid, p-(1-hydroxy-2-oxo-3-piperidinyl)- …
Matched Name: … (1-Hydroxy-2-oxopiperidin-3-yl)phosphonic acid
Matched Iupac: … (1-hydroxy-2-oxopiperidin-3-yl)phosphonic acid
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Synonyms: … (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and
Matched Products: … OKACIN GOZ DAMLASI 3 MG/ML 5 ML …
Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has...
Approved
Investigational
Matched Description: … (IL-17A) and prevents it from interacting with the IL-17A receptor. ... heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for ... Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents ... Interleukin-17 ... Interleukin-17A Antagonist …
Matched Products: … COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 ADET ... COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 3 ADET ... COPELLOR 80 MG/1 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
An antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.
Approved
Investigational
Matched Synonyms: … 6-Aminocaproic acid ... Aminocaproic acid ... 6-aminohexanoic acid
Matched Name: … Aminocaproic acid
Matched Iupac: … 6-aminohexanoic acid
Matched Mixtures name: … NAVI Black and C-Clinic ... Relief and Nature Toothpast E Jasmine Mint …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids
Matched Products: … Aminocaproic Acid ... Aminocaproic acid
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. ... This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Products: … Roferon-A Solution 18 Million I.U./3ml ... ROFERON-A 3 MIU IU ENEJKSİYONA HAZIR ŞIRINGA, 1 ADET ... Roferon A Sterile Pws 3m Unit/vial …
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Description: … A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety …
Matched Mixtures name: … POLIMISIN GÖZ MERHEMI, 3,5 G ... HEKSA 30 MG/G + 10000 I.U./G MERHEM …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Antiinfectives and Antiseptics for Local Oral Treatment ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … TERRAFUNGIN 100 MG/2 ML AMPUL, 3 ADET ... TERRAFUNGIN 250 MG/2 ML AMPUL, 3 ADET ... TERRAFUNGIN 100 MG/2 ML AMPUL, 1 ADET …
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Salts cas: … 404858-36-2 …
Experimental
Matched Name: … 3-(1-Aminoethyl)Nonanedioic Acid
Matched Iupac: … (3S)-3-[(1S)-1-aminoethyl]nonanedioic acid
Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl ... ]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo ... [22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone …
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Salts cas: … 109581-93-3
Matched Mixtures name: … Hyaluronic Acid Sodium Salt 1% / Tacrolimus 0.1% / Urea 20% ... Hyaluronic Acid Sodium Salt 1% / Niacinamide 4% / Tacrolimus 0.1% …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Skin and Mucous Membrane Agents …
Matched Products: … ENVARSUS 1 MG UZUN SALIMLI TABLET, 30 ADET ... ADVAGRAF 1 MG UZUN SALIMLI SERT KAPSÜL, 30 ADET ... ADVAGRAF 3 MG UZATILMIŞ SALIMLI SERT KAPSÜL, 100 ADET …
An anionic surface-active agent used for its wetting properties in industry and used in medicine as an irritant and sclerosing agent for hemorrhoids and varicose veins.
Approved
Investigational
Matched Description: … irritant and sclerosing agent for hemorrhoids and varicose veins. ... An anionic surface-active agent used for its wetting properties in industry and used in medicine as an …
Matched Categories: … Acids ... Sulfur Acids ... Sulfonic Acids ... Alkanesulfonic Acids
Matched Products: … Tromboject 3% ... Tromboject 1% ... Trombovar Inj 1% …
Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched International brands: … Montelo-10
Matched Synonyms: … 1-[[[(1 R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl] phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl] ... (R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl ... )thio)methyl)cyclopropaneacetic acid
Matched Iupac: … 2-[1-({[(1R)-1-{3-[(1E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl ... ]sulfanyl}methyl)cyclopropyl]acetic acid
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... [A178651] And although these kinds of effects are currently included in the official prescribing information …
Matched Salts cas: … 151767-02-1
Matched Mixtures name: … BRONCHOREST 10 MG/5 MG KAPSÜL ,30 KAPSÜL ... LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADET ... AIRCOMB 5/10 MG FILM KAPLI TABLET, 30 ADET …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … MONTAS-10 FILM COATED TABLET 10 MG ... มอนเท็ค 10 ... MONAST 10 (Montelukast Sodium Tablets 10 mg) …
Investigational
Matched Synonyms: … 4-((4-AMINO-3-(4-CYCLOHEXYLPIPERAZIN-1-YL)-9,10-DIOXO-9,10-DIHYDROANTHRACEN-1-YL)AMINO)BENZOIC ACID ... 4-{[4-Amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid ... BENZOIC ACID, 4-((4-AMINO-3-(4-CYCLOHEXYL-1-PIPERAZINYL)-9,10-DIHYDRO-9,10-DIOXO-1-ANTHRACENYL)AMINO) …
Matched Iupac: … 4-{[4-amino-3-(4-cyclohexylpiperazin-1-yl)-9,10-dioxo-9,10-dihydroanthracen-1-yl]amino}benzoic acid
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Iupac: … 12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13- …
Matched Description: … approved for the acute treatment of distinctive intermittent, stereotypic seizure episodes in patients 12 ... and endoscopic procedures as pre-anesthetic medication, and as an adjunct to local anesthesia. ... years of age and older. …
Matched Categories: … Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Hypnotics and Sedatives …
Matched Products: … MIDAZOLAM 15 MG/3ML ... MIDAZOLAM 15 MG/ 3 ML ... Miloz Injection 15 mg/3 ml …
Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Iupac: … (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22 ... dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1^{4,7}.0^{5,28}]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13
Matched Description: … [A39986] Rifamycin was further developed by Cosmo Technologies Ltd and approved in November 16, 2018 ... Some small modifications where performed in this inactive compound and with the creation of rifamycin ... Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] …
Matched Salts cas: … 14897-39-3
Matched Mixtures name: … RIFETEM 250 MG / 3 ML AMPUL, 1 ADET ... RIFOCIN 250 MG+10 MG/3 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 100 ADET ... RIFOCIN 250 MG+10 MG/3 ML IM ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN AMPUL, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... MATE 1 Inhibitors …
Matched Products: … Rifoxtem 250 mg/3 mL Enjeksiyonluk Çözelti, 1 ADET ... Rifoxtem 250 mg/3 mL Enjeksiyonluk Çözelti, 50 ADET ... RIFAMISIN 125 MG/1.5 ML AMPUL, 1 ADET …
Experimental
Matched Synonyms: … 3-Cyclohexanepropionic acid ... 3-Cyclohexylpropanoic acid ... 3-Cyclohexylpropionic acid
Matched Name: … Cyclohexanepropanoic acid
Matched Iupac: … 3-cyclohexylpropanoic acid
Experimental
Matched Synonyms: … 1H-Indole-3-propionic acid ... 3-(3-Indole)propionic acid ... 3-(3-Indolyl)propanoic acid
Matched Name: … Indolepropionic acid
Matched Iupac: … 3-(1H-indol-3-yl)propanoic acid
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Laninamivir octanoate has been used in trials studying the treatment of Asthma.
Investigational
Matched Name: … Laninamivir octanoate
Matched Iupac: … (2R,3R,4S)-4-carbamimidamido-3-acetamido-2-[(1R,2R)-2-hydroxy-1-methoxy-3-(octanoyloxy)propyl]-3,4-dihydro ... -2H-pyran-6-carboxylic acid
Matched Description: … Laninamivir octanoate has been used in trials studying the treatment of Asthma. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Acids, Acyclic ... Sugar Acids ... Sialic Acids ... Hydroxy Acids
Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Iupac: … 4-[2-(dipropylamino)ethyl]-2,3-dihydro-1H-indol-2-one …
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and
Matched Products: … ROPINIROL ACIS 2MG ... ROPINIROL 1A PHARMA 3MG ... ROPINIROL-HEXAL 3MG
Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved
Matched Synonyms: … (1R,3R)-1-amino-3(18F)fluorocyclobutane-1-carboxylic acid ... Anti-1-amino-3-(18F)fluorocyclobutane-1-carboxylic acid ... (18F)FACBC …
Matched Name: … Fluciclovine (18F) …
Matched Iupac: … (1r,3r)-1-amino-3-(¹⁸F)fluorocyclobutane-1-carboxylic acid
Matched Description: … [A31385] Fluciclovine was developed by Blue Earth Diagnostics, Ltd. and FDA approved in May 27, 2016. ... Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. ... [A31384] The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid
Matched Categories: … fluciclovine (18F) …
Displaying drugs 626 - 650 of 6142 in total