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Displaying drugs 651 - 675 of 12887 in total
Sotagliflozin
Sotagliflozin is a dual inhibitor of SGLT1 and SGLT2, the first of its kind, which is approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 diabetes mellitus (T1DM) and a BMI ≥27 kg/m2. Its potency in inhibiting SGLT2 is similar...
Approved
Investigational
Matched Iupac: … (2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl}-6-(methylsulfanyl)oxane-3,4,5-triol …
Matched Description: … approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 ... [L39739] On March 22, 2022, the marketing authorization of sotagliflozin for the treatment of type 1 ... was approved by the EMA under the brand name "Zynquista" on April 26, 2019, for the treatment of type 1 …
Matched Categories: … Sodium-Glucose Transporter 1, antagonists & inhibitors …
Matched Description: … approved for use in the EU, in combination with insulin, to improve glycemic control in patients with type 1 ... [L39739] On March 22, 2022, the marketing authorization of sotagliflozin for the treatment of type 1 ... was approved by the EMA under the brand name "Zynquista" on April 26, 2019, for the treatment of type 1 …
Matched Categories: … Sodium-Glucose Transporter 1, antagonists & inhibitors …
Nilutamide
Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Human papillomavirus type 11 L1 capsid protein antigen
Human papillomavirus type 11 L1 capsid protein antigen is contained in Gardasil, or a recombinant Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) vaccine for intramuscular injection. It is an immunization for young men and women 9-26 years of age for the prevention of diseases caused by Human Papillomavirus...
Approved
Matched Mixtures name: … GARDASİL 9 IM ENJEKSİYONLUK SÜSPANSİYON, 1 ADET ŞIRINGA+2 ADET İĞNE …
Lomifylline
Approved
Matched Synonyms: … 7-(5-oxohexyl)theophylline …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Matched Iupac: … 1,3-dimethyl-7-(5-oxohexyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione …
Tiaprofenic acid
Tiaprofenic acid is a non-steroidal anti-inflammatory drug employed in the treatment of pain, particularly arthritis pain. It belongs to the arylpropionic acid (profen) group of nonsteroidal anti-inflammatory drugs (NSAIDs).
Approved
Matched Synonyms: … 2-(5-Benzyl-2-thienyl)propionsäure ... 2-(5-Benzoyl-thiophen-2-yl)-propionic acid ... 5-benzoyl-α-methyl-2-thiopheneacetic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Matched Iupac: … 2-(5-benzoylthiophen-2-yl)propanoic acid …
Citalopram
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Matched Categories: … Serotonin 5-HT2 Receptor Antagonists …
Droxidopa
Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Categories: … Adrenergic alpha-1 Receptor Agonists ... Adrenergic beta-1 Receptor Agonists …
Sargramostim
Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Approved
Investigational
Sodium borate
Approved
Experimental
Cobimetinib
Cobimetinib is an orally active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), and central components of the RAS/RAF/MEK/ERK signal transduction pathway. It has been approved in Switzerland and the US, in combination with vemurafenib for the treatment of patients with unresectable or...
Approved
Investigational
Matched Iupac: … 1-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl}-3-[(2S)-piperidin-2-yl]azetidin-3-ol …
Matched Description: … active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... MAP Kinase Kinase 1, antagonists & inhibitors …
Matched Description: … active, potent and highly selective small molecule inhibiting mitogen-activated protein kinase kinase 1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... MAP Kinase Kinase 1, antagonists & inhibitors …
Vilazodone
Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Iupac: … 5-{4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxamide …
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists …
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Serotonin 5-HT1 Receptor Agonists …
Pyridoxine
Pyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body. While many plants and microorganisms are...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … 5-hydroxy-6-methyl-3,4-pyridinedimethanol …
Matched Description: … B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s ... -phosphate, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. ... More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important …
Matched Mixtures name: … ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5) ... Pregvit Folic 5 ... Pregvit Folic 5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Pyridoxine-S Tab 50mg ... VI-PLEX B6 50 MG AMPUL, 5 ADET ... VI-PLEX B6 200 MG AMPUL, 5 ADET …
Matched Description: … B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s ... -phosphate, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. ... More specifically, pyridoxine is converted to pyridoxal 5-phosphate in the body, which is an important …
Matched Mixtures name: … ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5) ... Pregvit Folic 5 ... Pregvit Folic 5 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Pyridoxine-S Tab 50mg ... VI-PLEX B6 50 MG AMPUL, 5 ADET ... VI-PLEX B6 200 MG AMPUL, 5 ADET …
Milk thistle
Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Fidaxomicin
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by Clostridioides (formerly Clostridium) difficile in adult and pediatric patients over the age of 6 months. Fidaxomicin is a naturally-occurring 18-member macrocycle derived from fermentation. Because fidaxomicin contains an 18-membered lactone ring in its structure, it is...
Approved
Matched Iupac: … 5-[(2-methylpropanoyl)oxy]oxan-2-yl]oxy}-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl ... -2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy}-4-hydroxy-5-methoxy-2-methyloxan-3-yl 3,5 ... (2R,3S,4S,5S,6R)-6-{[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-{[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl- …
Setmelanotide
Setmelanotide is the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, or leptin deficiencies. It is an agonist of the melanocortin 4 receptor. Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. Other...
Approved
Investigational
Matched Iupac: … (4R,7S,10S,13R,16S,19R,22R)-13-benzyl-22-[(2S)-5-[(diaminomethylidene)amino]-2-acetamidopentanamido]- ... 10-{3-[(diaminomethylidene)amino]propyl}-16-[(1H-imidazol-5-yl)methyl]-7-[(1H-indol-3-yl)methyl]-19-methyl …
Matched Description: … the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, …
Matched Description: … the first available treatment for patients with pro-opiomelanocortin, proprotein subilisin/kexin type 1, …
Aceclofenac
Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is reported to have a higher anti-inflammatory action or at least comparable effects than conventional NSAIDs in double-blind studies [A19667, A19668, A19670]. Aceclofenac potently inhibits the...
Approved
Investigational
Technetium Tc-99m exametazime
Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases. It can also be used for the labelling of leukocytes to localise intra-abdominal infections and inflammatory bowel disease. Exametazime, also known as hexamethylpropyleneamine...
Approved
Botulinum toxin type B
Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
Approved
Investigational
Ethionamide
A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Potassium
Potassium is an essential nutrient, like Calcium and Magnesium. It was identified as a shortfall nutrient by the 2015-2020 Advisory Committee of Dietary Guidelines for Americans. Many conditions and diseases interfere with normal body potassium balance, and underconsumption of potassium is one example. Hypokalemia (low potassium) or hyperkalemia (high potassium)...
Approved
Experimental
Matched Mixtures name: … Aqua-S Supplement ... Calcium and Magnesium 1:1 Plus Tablets ... KORDEL`S NUTRITIME TABLET …
Beta carotene
Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Iupac: … en-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl]cyclohex-1-ene ... 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex-1- …
Matched Mixtures name: … Pregvit Folic 5 ... Pregvit Folic 5 ... Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap …
Matched Mixtures name: … Pregvit Folic 5 ... Pregvit Folic 5 ... Kordel"s Bio-Liquid Women"s Multi With Fish Oil Vegicap …
Displaying drugs 651 - 675 of 12887 in total