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Displaying drugs 676 - 700 of 5157 in total
First-in-class potent and selective inhibitor of the BRD4 signaling pathway.
Investigational
Matched Synonyms: … (s)-(+)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... Tert-butyl 2-((6s)-4-(4-chlorophenyl)-2,3,9-trimethyl-6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin ... 6h-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl …
Matched Iupac: … tert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6 ... }]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
Matched Description: … First-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967] …
Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … English Walnut Shell ... Walnut Shell Powder ... Walnut Shell Extract …
Matched Name: … Juglans regia shell
Matched Description: … Juglans regia shell is a plant/plant extract used in some OTC (over-the-counter) products. …
In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Approved
Withdrawn
Matched Synonyms: … (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol …
Matched Iupac: … 1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol …
Matched Categories: … Benzene Derivatives …
Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe. It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure.
Approved
Matched Synonyms: … N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine ... (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine …
Matched Iupac: … [(1R)-1-(naphthalen-1-yl)ethyl]({3-[3-(trifluoromethyl)phenyl]propyl})amine …
Matched Description: … and as Mimpara® in Europe. ... Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia …
Matched Categories: … Calcium-Regulating Hormones and Agents ... Naphthalenes ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... Calcium Homeostasis …
Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics.
Approved
Matched Synonyms: … Cetyl-Trimethyl-Ammonium ... Cetrimonium cation ... Cetyltrimethylammonium cation
Matched Description: … Cetrimonium is a quaternary ammonium cation whose salts are used as antiseptics. …
Matched Mixtures name: … Dermoplex Bite and Sting Cream ... NW BENZALKONIUM AND CETRIMIDE CREAM ... SANIDINA® JABON LIQUIDO
Matched Categories: … Antiseptics and Disinfectants ... Trimethyl Ammonium Compounds ... Quaternary Ammonium Compounds …
Matched Products: … Resdan Dandruff Treatment Liquid 1% ... Zheng bacteriostatic solution ... CETYL SOLUSYON, 100 CC …
17-Hydroxy-6-methylpregna-3,6-diene-3,20-dione. A progestational hormone used most commonly as the acetate ester. As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor. It has also been used in the palliative treatment of breast cancer.
Approved
Investigational
Vet approved
Matched Synonyms: … 6-Methyl-17α-hydroxy-delta(sup 6)-progesterone acetate ... 6-Methyl-17alpha-hydroxy-delta(sup 6)-progesterone acetate ... 6-Methyl-delta(sup 4,6)-pregnadien-17α-ol-3,20-dione acetate
Matched Name: … Megestrol acetate
Matched Iupac: … ,11S,14R,15S)-14-acetyl-2,8,15-trimethyl-5-oxotetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-6,8-dien-14-yl acetate
Matched Description: … As the acetate, it is more potent than progesterone both as a progestagen and as an ovulation inhibitor ... A progestational hormone used most commonly as the acetate ester. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones and Related Agents ... Genito Urinary System and Sex Hormones ... megestrol and estrogen …
Matched Products: … Megestrol Acetate ... Megestrol acetate ... MEGESTROL ACETATE
A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Synonyms: … Acide gadopentetique ... Acidum gadopenteticum ... Gadopentetic acid
Matched Name: … Gadopentetic acid
Matched Iupac: … gadolinium(3+) 2-[bis({2-[bis(carboxymethyl)amino]ethyl})amino]acetate
Matched Description: … acid), that is given to enhance the image in cranial and spinal MRIs. ... A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids ... gadopentetic acid
Matched Products: … ACIDO GADOPENTETICO SANOCHEMIA PHARMAZEUTIKA ... MAGNEVIST® SOLUCION INYECTABLE …
Experimental
Matched Name: … Carbazochrome sulfonic acid
Matched Iupac: … (5Z)-5-[(carbamoylamino)imino]-1-methyl-6-oxo-2,3,5,6-tetrahydro-1H-indole-2-sulfonic acid
Matched Mixtures name: … HEMOSIN-K SOLUCIÓN ORAL …
Panobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. The approval was accelerated based on progression-free survival, therefore confirmatory trials by the sponsor to demonstrate clinical efficacy in multiple myeloma treatment are in progress of being conducted. Panobinostat...
Approved
Investigational
Matched Synonyms: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide ... 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)- …
Matched Iupac: … (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide …
Matched Description: … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Carboxylic Acids ... Hydroxy Acids ... Hydroxamic Acids
N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid.
Experimental
Matched Synonyms: … Ethyl retinamide ... Vitamin A acid ethylamide …
Matched Iupac: … (2E,4E,6E,8E)-N-ethyl-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenamide …
Matched Description: … N-Ethylretinamide is the ethylamide of all-trans B-retinoic acid. …
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Approved
Investigational
Vet approved
Matched Description: … It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … VOMETA ... VOMINA ... VOMITAS
Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Approved
Experimental
Matched Synonyms: … Acide stéarique ... Stearic acid ... Acide octadécanoïque …
Matched Name: … Stearic acid
Matched Iupac: … octadecanoic acid
Matched Description: … acids that comes from many animal and vegetable fats and oils. ... Stearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty …
Matched Categories: … Fatty Acids ... Stearic Acids
Investigational
Matched Synonyms: … 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)benzoic acid ... Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)- …
Matched Iupac: … 2-hydroxy-5-({2-[4-(trifluoromethyl)phenyl]ethyl}amino)benzoic acid
Matched Categories: … Benzene Derivatives …
Experimental
Matched Name: … 9-Methyl Uric Acid
Matched Iupac: … 9-methyl-2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione …
Investigational
Matched Synonyms: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid
Matched Name: … Cannabidiolic acid methyl ester …
Matched Iupac: … 2-{2,4-dihydroxy-3-[(1R,6R)-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-en-1-yl]-6-pentylphenyl}acetic acid
3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein biphenyl-2,3-diol 1,2-dioxygenase.
Experimental
Matched Name: … 3-methyl-benzene-1,2-diol …
Matched Description: … 3-methyl-benzene-1,2-diol is a solid. This compound belongs to the catechols. ... These are compounds containing a 1,2-benzenediol moeity. 3-methyl-benzene-1,2-diol targets the protein …
The use of benoxaprofen, formerly marketed as Oraflex tablets, was associated with fatal cholestatic jaundice among other serious adverse reactions. The holder of the approved application voluntarily withdrew Oraflex tablets from the market on August 5, 1982.
Approved
Withdrawn
Matched Synonyms: … 2-(4-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid ... 2-(4-Chlorophenyl)-alpha-methyl-5-benzoxazoleacetic acid ... 2-(p-chlorophenyl)-α-methyl-5-benzoxazoleacetic acid
Matched Iupac: … 2-[2-(4-chlorophenyl)-1,3-benzoxazol-5-yl]propanoic acid
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Acyclic ... Fatty Acids ... Carboxylic Acids
Experimental
Matched Synonyms: … 5-Naphthylamine-1-sulfonic acid ... Laurent acid ... 1-Amino-5-naphthalenesufonic acid
Matched Name: … 1-Naphthylamine-5-sulfonic acid
Matched Iupac: … 5-aminonaphthalene-1-sulfonic acid
Matched Categories: … Sulfur Acids ... Sulfonic Acids ... Naphthalenes ... Arylsulfonic Acids ... Sulfur Compounds …
Ferric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin biopsies.
Approved
Experimental
Matched Synonyms: … Monsel's solution ... basic ferric sulfate solution
Matched Categories: … Sulfur Acids ... Sulfuric Acids ... Sulfur Compounds …
Matched Products: … Monsels Solution ... Monsels solution
A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Description: … A compound formed in the liver from ammonia produced by the deamination of amino acids. ... It is the principal end product of protein catabolism and constitutes about one half of the total urinary …
Matched Mixtures name: … Bare 40 Plus SA ... Kerasal Topical Solution ... Lactic Acid 10% / Urea 40% …
Matched Categories: … Blood Substitutes and Perfusion Solutions ... Blood and Blood Forming Organs ... Emollients and Protectives ... Solutions ... Solutions Producing Osmotic Diuresis …
Matched Products: … UREA ACIS 12% CREME ... Carmol 40 ... Carb-O-Philic …
(S)-camphor, or L(-)-Camphor, is a stereoisomer of DB01744, a bicyclic monoterpene known to potentiate both heat and cold sensations . (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and current inhibition . DB01744 is isolated from the wood of the camphor laurel tree, Cinnamomum camphora, and...
Experimental
Matched Synonyms: … l-camphor ... (−)-camphor ... (1S,4S)-camphor
Matched Name: … (S)-camphor
Matched Description: … (S)-camphor is not the naturally-occurring stereoisomer but displays similar TRPV channel affinity and ... [DB01744] is isolated from the wood of the camphor laurel tree, _Cinnamomum camphora_, and had a long ... Camphor is a major active ingredient in over-the-counter balms and liniments supplied as topical analgesics …
Matched Mixtures name: … Menthol, Camphor ... Menthol, Camphor ... Elixicure All Natural Original …
Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Synonyms: … Bicyclohexyl-1-carboxylic acid 2-diethylamino-ethyl ester ... 2-(diethylamino)ethyl 1-cyclohexylcyclohexanecarboxylate …
Matched Iupac: … 2-(diethylamino)ethyl [1,1'-bi(cyclohexane)]-1-carboxylate …
Matched Description: … of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder ... Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor ... and irritable bowel syndrome. …
Matched Categories: … Alimentary Tract and Metabolism ... Acids, Carbocyclic ... Carboxylic Acids ... Cyclohexanecarboxylic Acids
Experimental
Matched Name: … Glutathione sulfonic acid
Matched Iupac: … (2S)-2-amino-4-{[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfoethyl]carbamoyl}butanoic acid
Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. Although not widely prescribed, it is used in combination with meprobamate for the treatment of sleep disorders in France under the trade name Mepronizine.
Experimental
Matched Synonyms: … 10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone
Matched Iupac: … 1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethan-1-one …
Matched Description: … Aceprometazine is a is a drug with neuroleptic and anti-histamine properties. …
Matched Categories: … Sulfur Compounds …
An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. [PubChem]
Experimental
Matched Synonyms: … Methyl glyoxal ... Acetyl formaldehyde
Matched Description: … It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated ... An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning ... cell preparations, in various culture media, and in vivo in certain animals. …
Displaying drugs 676 - 700 of 5157 in total