Displaying drugs 676 - 700 of 721 in total
Tirabrutinib
Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).
Investigational
Matched Synonyms: … ONO-4059 (free base) …
Matched Description: … 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). ... Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …
Matched Description: … 4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)). ... Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS- …
Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine
The Covifenz COVID-19 vaccine (plant-based virus-like particles (VLP), recombinant, adjuvanted) is a plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada for the prevention of COVID-19. It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with...
Approved
Matched Name: … Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine …
Matched Description: … plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada ... speed and ease of manufacturing and increased immunogenicity. ... composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and …
Matched Description: … plant-based vaccine developed in partnership by Medicago and GlaxoSmithKline which is approved in Canada ... speed and ease of manufacturing and increased immunogenicity. ... composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and …
Alendronic acid
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Description: … is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and …
Matched Categories: … alendronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ALENDRONSAEURE BASICS 10MG ... ALENDRONSAEURE BASICS 70MG …
Matched Categories: … alendronic acid and colecalciferol ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid and alfacalcidol, sequential ... alendronic acid, calcium and colecalciferol, sequential …
Matched Products: … ALENDRONSAEURE BASICS 10MG ... ALENDRONSAEURE BASICS 70MG …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … codes for a modified immunogenic, streptococcal Emm55 protein, complexed with in vivo-jetPEI¬Æ polymer-based …
Entecavir
Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents...
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) in March 2005. ... Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the ... manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR BASICS 1MG FTA ... ENTECAVIR BASICS 0.5MG FTA …
Matched Categories: … Nucleosides and Nucleotides ... Nucleoside and Nucleotide Reverse Transcriptase Inhibitors …
Matched Products: … ENTECAVIR BASICS 1MG FTA ... ENTECAVIR BASICS 0.5MG FTA …
Anastrozole
Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Description: … provides stark advantages including a lack of steroid-associated adverse effects such as weight gain and ... drugs of choice in the treatment of postmenopausal breast cancer due to a more favourable efficacy and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ANASTROZOL BASIC 1MG FILMT …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … ANASTROZOL BASIC 1MG FILMT …
Carbinoxamine
Carbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and...
Approved
Matched Synonyms: … Carbinoxamine base …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
Matched Description: … The product label for carbinoxamine as an over the counter cough and cold medicine is being modified ... to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many ... labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and …
Schisandra chinensis fruit
Schisandra chinensis fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Five-flavoured Seed …
Chamomile
Chamomile is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Chamomilla Vulgaris Flower …
Cefpodoxime
Cefpodoxime is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and Gram negative bacteria. Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Approved
Vet approved
Matched Description: … is an oral third generation cephalosporin antibiotic with effectiveness against most Gram positive and ... which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime. ... Commonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug …
Matched Products: … CEFPO BASICS 100MG FILMTAB ... CEFPO BASICS 200MG FILMTAB …
Matched Products: … CEFPO BASICS 100MG FILMTAB ... CEFPO BASICS 200MG FILMTAB …
Valsartan
Valsartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, olmesartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and synthesis of aldosterone...
Approved
Investigational
Matched Description: … Overall, valsartan's physiologic effects lead to reduced blood pressure, lower aldosterone levels, reduced ... [A174124,A173869]
Valsartan was initially approved in 1996 in Europe for the treatment of hypertension ... aldosterone and ADH, cardiac stimulation, and renal reabsorption of sodium, among others. …
Matched Mixtures name: … VALSARTAN CO BAS 160/25MG ... VALSARTAN CO BAS 160/25MG ... VALSARTAN CO BAS 160/25MG …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren ... valsartan and amlodipine …
Matched Products: … VALSARTAN BASICS 40MG FTA ... VALSARTAN BASICS 80MG FTA ... VALSARTAN BASICS 160MG FTA …
Matched Mixtures name: … VALSARTAN CO BAS 160/25MG ... VALSARTAN CO BAS 160/25MG ... VALSARTAN CO BAS 160/25MG …
Matched Categories: … Angiotensin II Antagonists and Diuretics ... valsartan and nebivolol ... valsartan and diuretics ... valsartan and aliskiren ... valsartan and amlodipine …
Matched Products: … VALSARTAN BASICS 40MG FTA ... VALSARTAN BASICS 80MG FTA ... VALSARTAN BASICS 160MG FTA …
Fluconazole
Fluconazole, commonly known as Diflucan, is an antifungal drug used for the treatment of both systemic and superficial fungal infections in a variety of tissues. It was initially approved by the FDA in 1990. This drug is an azole antifungal, in the same drug family as ketoconazole and itraconazole. Fluconazole...
Approved
Investigational
Matched Description: … Fluconazole, commonly known as _Diflucan_, is an antifungal drug used for the treatment of both systemic and ... This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. …
Matched Mixtures name: … GINDEX®TABLETAS …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FLUCONAZOL BASICS 50MG ... FLUCONAZOL BASICS 100MG ... FLUCONAZOL BASICS 150MG …
Matched Mixtures name: … GINDEX®TABLETAS …
Matched Categories: … Imidazole and Triazole Derivatives ... Triazole and tetrazole derivatives ... azithromycin, fluconazole and secnidazole ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … FLUCONAZOL BASICS 50MG ... FLUCONAZOL BASICS 100MG ... FLUCONAZOL BASICS 150MG …
Anti-SARS-CoV-2 immunoglobulin
Hyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. Anti-coronavirus immunoglobulin is derived from COVID-19 convalescent plasma(https://go.drugbank.com/drugs/DB15692) but contains more SARS-CoV-2 neutralizing antibodies than found in convalescent plasma (https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.[L27521, L27526]
Investigational
Matched Synonyms: … SARS-CoV-2 antibody-based IVIG …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and ... [convalescent plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Activated charcoal
Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high...
Approved
Matched Description: … However its effects is rendered poor on some compounds including strong acids or bases, methanol and ... oral ingestion of certain medications or poisons by absorbing most drugs and toxins. ... passed over its surface to make a fine network of pores, producing a material with large surface area and …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Char-flo Aqueous Base - Sus Orl 208mg/ml …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents …
Matched Products: … Char-flo Aqueous Base - Sus Orl 208mg/ml …
Solifenacin
Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Description: … muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and …
Matched Categories: … tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … SOLIFENACIN BASICS 5MG ... SOLIFENACIN BASICS 10MG …
Matched Categories: … tamsulosin and solifenacin ... Genito Urinary System and Sex Hormones ... Drugs for Urinary Frequency and Incontinence …
Matched Products: … SOLIFENACIN BASICS 5MG ... SOLIFENACIN BASICS 10MG …
Imatinib
Imatinib is a small molecule kinase inhibitor that revolutionized the treatment of cancer, particularly chronic myeloid leukemia, in 2001. It was deemed a "miracle drug" due to its clinical success, as oncologist Dr. Brian noted that "complete hematologic responses were observed in 53 of 54 patients with CML treated with...
Approved
Matched Description: … responses were observed in 53 of 54 patients with CML treated with a daily dosage of 300 mg or more and ... [L42220]
Imatinib was approved on February 1st ,2001 by the FDA and November 7th, 2001 by the EMA ... ; however, its European approval has been withdrawn in October 2023. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATINIB BASICS 100MG ... IMATINIB BASICS 400MG …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Benzamides and benzamide derivatives …
Matched Products: … IMATINIB BASICS 100MG ... IMATINIB BASICS 400MG …
Cefixime
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Description: … , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... through inhibition of essential PBPs, result in impaired cell wall homeostasis, loss of cell integrity, and …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … CEFIXIMA ORCHID EUROPE …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Matched Products: … CEFIXIMA ORCHID EUROPE …
Atorvastatin
Atorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. By inhibiting the endogenous production of cholesterol in the liver, statins lower abnormal cholesterol and lipid levels, and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,...
Approved
Matched Description: … low-risk individuals (with <10% risk of a major vascular event occurring within five years) statin use leads ... lipid levels, and ultimately reduce the risk of cardiovascular disease. ... Bruce Roth and approved by the FDA in 1996. …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … ATORVASTATIN BASICS 10MG ... ATORVASTATIN BASICS 20MG ... ATORVASTATIN BASICS 30MG …
Matched Mixtures name: … Amlodipine Besylate and Atorvastatin Calcium ... Amlodipine and atorvastatin ... Amlodipine and atorvastatin …
Matched Categories: … atorvastatin and ezetimibe ... atorvastatin and amlodipine ... atorvastatin and perindopril ... atorvastatin, amlodipine and ramipril ... atorvastatin and acetylsalicylic acid …
Matched Products: … ATORVASTATIN BASICS 10MG ... ATORVASTATIN BASICS 20MG ... ATORVASTATIN BASICS 30MG …
Levocetirizine
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Categories: … Cetirizine and isomer …
Matched Products: … Basic Care Allergy Relief …
Matched Products: … Basic Care Allergy Relief …
Ezetimibe
Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Description: … , and these mice were insensitive to ezetimibe treatment - it was determined based on these findings ... Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption ... The discovery and research of this drug began in the early 1990s, after the intravenous administration …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... rosuvastatin and ezetimibe ... bempedoic acid and ezetimibe …
Matched Products: … EZETIMIB BASICS 10MG …
Matched Mixtures name: … Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin ... Ezetimibe and Simvastatin …
Matched Categories: … simvastatin and ezetimibe ... pravastatin and ezetimibe ... atorvastatin and ezetimibe ... rosuvastatin and ezetimibe ... bempedoic acid and ezetimibe …
Matched Products: … EZETIMIB BASICS 10MG …
Displaying drugs 676 - 700 of 721 in total