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Displaying drugs 701 - 725 of 2798 in total

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid ... (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Salts name: … Trimethoprim hydrochloride …
Matched Categories: … Folic Acid Antagonists ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Trimethoprim and Derivatives ... Sulfonamides and trimethoprim ... sulfametrole and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Antineoplastic and Immunomodulating Agents ... Prednisolone and Prodrugs ... Sex Hormones and Insulins …
Matched Products: … PREDNISOLON ACIS 5MG ... PREDNISOLON ACIS 10MG ... PREDNISOLON ACIS 20MG …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … [L8417] One unique property of this drug is that it does not increase gastric acid secretion. ... Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Salts name: … Vilazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …

Moricizine

An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester ... ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate ... ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Matched Salts name: … Moricizine hydrochloride …

Calcium citrate

Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements.
Approved
Investigational
Matched Name: … Calcium citrate …
Matched Description: … Calcium citrate is a salt typically used as a source of calcium in a variety of over the counter supplements …
Matched Mixtures name: … Calcium and Mag-potass and Zinc Cap ... Calcium, Magnesium, Zinc and D ... Eden With Calcium and Vitamin D …
Matched Salts name: … Calcium citrate malate ... Calcium citrate tetrahydrate …
Matched Categories: … ascorbic acid (vit C) and calcium ... Calcium-Regulating Hormones and Agents ... Alimentary Tract and Metabolism ... Diet, Food, and Nutrition ... Acids, Acyclic …
Matched Products: … Calcium 350 Mg (calcium Citrate) - Caplet ... Calcium 350 Mg (calcium Citrate) Caplet ... Calcium Citrate …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …

Thiamine(1+) monophosphate

Experimental
Matched Name: … Thiamine(1+) monophosphate …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …

Ropinirole

Ropinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease. In 2005, it was the first...
Approved
Investigational
Matched Description: … Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and ... offering a similar side effect profile and efficacy to previous formulations of ropinirole [A35711]. ... capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and …
Matched Salts name: … Ropinirole Hydrochloride …
Matched Products: … Ropinirole Hydrochloride ... ROPINIROL ACIS 2MG …

Tositumomab I-131

Investigational
Matched Synonyms: … Iodine I131 tositumomab ... Iodine I 131 tositumomab ... Iodine (131I) tositumomab …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Fenoprofen

An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … (+/-)-m-phenoxyhydratropic acid ... 3-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid …
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid …
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Salts name: … Fenoprofen calcium …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS …
Matched Products: … Fenoprofen Calcium …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …

Benazepril

Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid …
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and …
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Benazepril hydrochloride …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... ACE Inhibitors and Diuretics ... benazepril and diuretics ... benazepril and amlodipine …
Matched Products: … Benazepril Hydrochloride ... Benazepril hydrochloride …

Clobetasol propionate

Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors. It has demonstrated superior activity compared to fluocinonide and was first described in the literature in 1974. Clobetasol Propionate was granted FDA approval on 27 December 1985.
Approved
Matched Description: … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described …
Matched Mixtures name: … Clobetasol Propionate 0.05% / Coal Tar 8% / Salicylic Acid 6% ... Ciclopirox Olamine 0.77% / Clobetasol Propionate 0.05% / Salicylic Acid 3%. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Clobetasol Propionate ANDA ... CLOBETASOL ACIS CREME ... CLOBETASOL ACIS SALBE …

Cadexomer iodine

Experimental
Matched Synonyms: … Cadexomer iodine …
Matched Name: … Cadexomer iodine …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... Iodine Compounds ... cadexomer iodine …

Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Approved
Matched Mixtures name: … Prilocaine Hydrochloride with Epinephrine ... Lidocaine and Prilocaine ... Lidocaine and Prilocaine …
Matched Salts name: … Prilocaine hydrochloride …
Matched Products: … Prilocaine Hydrochloride ... Dentsply 4% Prilocaine Hydrochloride Dental Injection …

Amitriptyline

Amitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.
Approved
Matched Mixtures name: … Perphenazine and Amitriptyline Hydrochloride ... Perphenazine and Amitriptyline Hydrochloride ... Chlordiazepoxide and Amitriptyline Hydrochloride …
Matched Salts name: … Amitriptyline hydrochloride …
Matched Categories: … amitriptyline and psycholeptics ... Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Amitriptyline Hydrochloride ... Amitriptyline hydrochloride ... AMITRIPTYLINE HYDROCHLORIDE …

Alfentanil

A short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Approved
Illicit
Matched Description: … A short-acting opioid anesthetic and analgesic derivative of fentanyl. ... It produces an early peak analgesic effect and fast recovery of consciousness. ... effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and …
Matched Salts name: … Alfentanil hydrochloride …
Matched Categories: … Fentanyl and fentanyl analogues …
Matched Products: … Alfentanil Hydrochloride …

Naratriptan

Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.
Approved
Investigational
Matched Salts name: … Naratriptan hydrochloride …
Matched Categories: … Serotonin-1b and Serotonin-1d Receptor Agonist …
Matched Products: … Naratriptan Hydrochloride …
Displaying drugs 701 - 725 of 2798 in total