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Displaying drugs 701 - 725 of 2717 in total

Tirofiban

Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Salts name: … Tirofiban hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Products: … Tirofiban Hydrochloride ... Tirofiban hydrochloride …

Terazosin

Terazosin is a quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and hypertension[FDA Label] . Terazosin blocks adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and the prostate .
Approved
Matched Description: … quinazoline derivative alpha-1-selective adrenergic blocking agent indicated for benign prostatic hyperplasia and ... adrenaline's action on alpha-1 adrenergic receptors, causing relaxation of smooth muscle in blood vessels and …
Matched Salts name: … Terazosin hydrochloride ... Terazosin hydrochloride hydrate …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … Terazosin Hydrochloride ... Terazosin hydrochloride ... Terazosin Hydrochloride Anhydrous …

Oxothiazolidinecarboxylic acid

Procysteine has been used in trials studying the treatment of HIV Infections.
Investigational
Matched Synonyms: … (-)-2-OXO-4-THIAZOLIDINECARBOXYLIC ACID ... (R)-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID ... L-2-OXO-4-THIAZOLIDINECARBOXYLIC ACI …
Matched Name: … Oxothiazolidinecarboxylic acid …
Matched Iupac: … (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids, Acidic ... Amino Acids ... Imino Acids ... Amino Acids, Cyclic …

Darigabat

Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and Tolerability of Darigabat in Participants With Panic Disorder).
Investigational
Matched Synonyms: … 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxybiphenyl-3-yl)-7h-imidazo(4,5-c)-pyridazine ... 7h-imidazo(4,5-c)pyridazine, 7-ethyl-4-(4'-(ethylsulfonyl)-6-fluoro-2'-methoxy(1,1'-biphenyl)-3-yl)- …
Matched Description: … Darigabat is under investigation in clinical trial NCT05941442 (A Study to Evaluate Efficacy, Safety, and …

Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.
Approved
Investigational
Matched Salts name: … Mexiletine hydrochloride …
Matched Products: … Mexiletine Hydrochloride ... Mexiletine hydrochloride …

Hydromorphone

Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and...
Approved
Illicit
Matched Description: … the absence of a double bond between the carbon 7 and 8. ... was developed by Fresenius Kabi USA and FDA approved in 1984. ... Due to these modifications, it presents a very high potency and comparable side effect profile to the …
Matched Salts name: … Hydromorphone hydrochloride …
Matched Categories: … hydromorphone and naloxone ... hydromorphone and antispasmodics …
Matched Products: … Hydromorphone Hydrochloride ... Hydromorphone hydrochloride ... HYDROmorphone Hydrochloride …

Levobunolol

A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Salts name: … Levobunolol hydrochloride …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … Levobunolol Hydrochloride ... Levobunolol Hydrochloride Ophthalmic Solution …

Procaterol

A long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Approved
Investigational
Matched Salts name: … Procaterol hydrochloride ... Procaterol hydrochloride hemihydrate …
Matched Products: … PROCATEROL HYDROCHLORIDE HEMIHYDRATE …

Vilazodone

Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain . Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Approved
Matched Description: … (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. ... Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine ... Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. …
Matched Salts name: … Vilazodone hydrochloride …
Matched Categories: … Serotonin antagonist and reuptake inhibitors (SARIs) …
Matched Products: … Vilazodone Hydrochloride ... Vilazodone hydrochloride …

Quinoline

Investigational
Matched Synonyms: … Benzo(b)pyridine …

Topotecan

An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.
Approved
Investigational
Matched Salts name: … Topotecan hydrochloride …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Topotecan hydrochloride ... Topotecan Hydrochloride ... Topotecan Hydrochloride for Injection …

Trimethoprim

Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival ... L11893] Trimethoprim is often used in combination with [sulfamethoxazole] due to their complementary and ... synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of urinary …
Matched Mixtures name: … Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim ... Sulfamethoxazole and Trimethoprim …
Matched Salts name: … Trimethoprim hydrochloride …
Matched Categories: … Folic Acid Antagonists ... isoniazid, sulfamethoxazole, trimethoprim and pyridoxine ... Trimethoprim and Derivatives ... Sulfonamides and trimethoprim ... sulfametrole and trimethoprim …
Matched Products: … TRIMPEX trimethoprim hydrochloride …

Imipramine

Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, imipramine exerts...
Approved
Matched Description: … and clomipramine. ... TCAs are potent inhibitors of serotonin and norepinephrine reuptake. ... than secondary amine TCAs, such as nortriptyline and desipramine. …
Matched Salts name: … Imipramine hydrochloride …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors …
Matched Products: … Imipramine Hydrochloride ... Imipramine hydrochloride ... Imipramine Hydrochloride Tablets 25mg …

Nalmefene

Nalmefene, a 6-methylene analogue of naltrexone, is an opioid receptor antagonist. It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist at the kappa (κ)-opioid receptor. In Europe, nalmefene oral tablets are used to reduce alcohol consumption in adults with alcohol dependence. Nalmefene...
Approved
Investigational
Withdrawn
Matched Description: … [L40684] It acts as an antagonist at the mu (μ)-opioid and delta (δ)-opioid receptors and a partial agonist …
Matched Salts name: … Nalmefene hydrochloride ... Nalmefene hydrochloride dihydrate …
Matched Products: … Nalmefene Hydrochloride …

Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.[A15638,L33160] Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising...
Approved
Investigational
Matched Description: … anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and ... found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and ... [A233724,A233729] The US patent from 1943 states that this compound had a wider therapeutic index and …
Matched Salts name: … Isoprenaline hydrochloride …
Matched Categories: … Adrenergic and Dopaminergic Agents ... isoprenaline and other drugs for obstructive airway diseases …
Matched Products: … Isoproterenol Hydrochloride ... Isoproterenol hydrochloride ... Isoproterenol Hydrochloride Injection USP …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Description: … Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative ... impact on quality of life and poses a significant burden on the healthcare system. ... [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated …
Matched Salts name: … Metoclopramide hydrochloride ... Metoclopramide hydrochloride anhydrous …
Matched Categories: … Alimentary Tract and Metabolism ... Benzamides and benzamide derivatives ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Metoclopramide Hydrochloride ... METOCLOPRAMIDE hydrochloride ... Metoclopramide hydrochloride …

Meperidine

A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
Approved
Matched Description: … that can be used for the relief of most types of moderate to severe pain, including postoperative pain and ... lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and …
Matched Mixtures name: … Meperidine Hydrochloride and Promethazine Hydrochloride ... Meperidine Hcl and Promethazine Hcl …
Matched Salts name: … Meperidine hydrochloride …
Matched Categories: … pethidine and antispasmodics ... Acids, Heterocyclic ... Isonipecotic Acids …
Matched Products: … Meperidine Hydrochloride ... Meperidine Hydrochloride Injection USP ... DBL PETHIDINE HYDROCHLORIDE INJECTION BP 50mg/ml …

Cinnamic acid

Investigational
Matched Synonyms: … Cinnamic acidum ... E-cinnamic acid ... 3-phenylacrylic acid …
Matched Name: … Cinnamic acid …
Matched Iupac: … (2E)-3-phenylprop-2-enoic acid …
Matched Categories: … Heparin and similars ... Acids, Carbocyclic ... Carboxylic Acids …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Salts name: … Naltrexone hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Products: … Naltrexone Hydrochloride ... Naltrexone Hydrochloride Tablets USP …

Finasteride

Finasteride is a synthetic 4-azasteroid compound and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT). It works in a similar fashion as dutasteride, which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. Finasteride is an orally active drug...
Approved
Matched Description: … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase ... first approved by the FDA in 1992 for the treatment of benign prostatic hyperplasia to improve symptoms and ... [L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo …
Matched Categories: … doxazosin and finasteride ... alfuzosin and finasteride ... finasteride and tadalafil ... Skin and Mucous Membrane Agents ... Genito Urinary System and Sex Hormones …
Matched Products: … FOLIX 1 MG TABLETAS …

PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE

Experimental
Matched Name: … PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE …

Prednisolone

Prednisolone is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone was granted FDA approval on 21 June 1955.
Approved
Vet approved
Matched Description: … glucocorticoid similar to [cortisol] used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and …
Matched Categories: … Alimentary Tract and Metabolism ... Prednisolone and Prodrugs ... Antineoplastic and Immunomodulating Agents ... Sex Hormones and Insulins ... prednisolone and mydriatics …
Matched Products: … PREDNISOLON ACIS 5MG ... PREDNISOLON ACIS 10MG ... PREDNISOLON ACIS 20MG …

Doxorubicin

Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. caesius along side with daunorubicin, another cytotoxic agent, in 1970.[A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain terminates with a primary alcohol group compared to the methyl group of daunorubicin. Although its detailed...
Approved
Investigational
Matched Description: … Hodgkin’s lymphoma, multiple myeloma, sarcoma, and pediatric cancers. ... [A1575,A257709,A257614] Although they both have aglyconic and sugar moieties, doxorubicin's side chain ... generally thought to exert its effect through DNA intercalation, which eventually leads to DNA damage and …
Matched Salts name: … Doxorubicin hydrochloride …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … Doxorubicin Hydrochloride ... DOXOrubicin Hydrochloride ... Doxorubicin hydrochloride …

Pimasertib

Pimasertib is under investigation in clinical trial NCT01378377 (Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus).
Investigational
Matched Synonyms: … N-[(2S)-2,3-dihydroxypropyl]-3-(2-fluoro-4-iodoanilino)pyridine-4-carboxamide …
Matched Iupac: … N-[(2S)-2,3-dihydroxypropyl]-3-[(2-fluoro-4-iodophenyl)amino]pyridine-4-carboxamide …
Matched Salts name: … Pimasertib hydrochloride …
Matched Categories: … Nicotinic Acids ... Acids, Heterocyclic …

Hydroxyzine

Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties.[A1257,A187589] It was first developed in 1955, and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. The active metabolite of hydroxyzine,...
Approved
Matched Description: … piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. ... Hydroxyzine is a first-generation histamine H1-receptor antagonist of the dephenylmethane and ... for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus. …
Matched Salts name: … Hydroxyzine hydrochloride …
Matched Categories: … Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Hydroxyzine hydrochloride ... Hydroxyzine Hydrochloride ... HydrOXYzine hydrochloride …
Displaying drugs 701 - 725 of 2717 in total