Displaying drugs 701 - 725 of 15366 in total
Adefovir dipivoxil
Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
Approved
Investigational
Matched International brands: … A Di Xian ... A Gan Ding …
Plicamycin
Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management of hypercalcemia. The manufacturer discontinued plicamycin in 2000.
Approved
Investigational
Withdrawn
Matched Iupac: … (2S,3S)-3-[(1S,3S,4R)-3,4-dihydroxy-1-methoxy-2-oxopentyl]-2-{[(2S,4R,5R,6R)-4-{[(2S,4R,5S,6R)-4-{[(2S ... dimethyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-methyloxan-2-yl]oxy}-6-{[(2S,4R,5R,6R)-4- …
Matched Description: … Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. ... The manufacturer discontinued plicamycin in 2000. ... It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Description: … Plicamycin is an antineoplastic antibiotic produced by Streptomyces plicatus. ... The manufacturer discontinued plicamycin in 2000. ... It has been used in the treatment of testicular cancer, Paget's disease of bone, and, rarely, the management …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Karaya gum
Karaya gum allergenic extract is used in allergenic testing.
Approved
Matched Description: … Karaya gum allergenic extract is used in allergenic testing. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Mechlorethamine
A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating drug. It was formerly used as a war gas. The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. It causes severe gastrointestinal and bone marrow damage.
The FDA granted marketing approval for the orphan...
Approved
Investigational
Matched Description: … It was formerly used as a war gas. ... The hydrochloride is used as an antineoplastic in Hodgkin's disease and lymphomas. ... A vesicant and necrotizing irritant destructive to mucous membranes, mechlorethamine is an alkylating …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Iohexol
Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.
Approved
Matched Description: … Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Articaine
Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Iupac: … methyl 4-methyl-3-[2-(propylamino)propanamido]thiophene-2-carboxylate …
Matched Description: … Articaine is a dental local anesthetic. ... Articaine is widely used around the world and is the most popular local anesthetic in many European countries …
Matched Mixtures name: … ARTINIBSA 4% WITH EPINEPHRINE 1 : 200000 ... ARTINIBSA 4% WITH EPINEPHRINE 1 : 100000 ... ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000 …
Matched Description: … Articaine is a dental local anesthetic. ... Articaine is widely used around the world and is the most popular local anesthetic in many European countries …
Matched Mixtures name: … ARTINIBSA 4% WITH EPINEPHRINE 1 : 200000 ... ARTINIBSA 4% WITH EPINEPHRINE 1 : 100000 ... ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000 …
Methadone
Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission. It also has a...
Approved
Matched Description: … [A497,A5344] Specifically by inhibiting the NMDA receptor, methadone dampens a major excitatory pain ... ; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids (due ... It also has a number of unique characteristics that have led to its increased use in the last two decades …
Matched Categories: … Drugs Used in Opioid Dependence ... Drugs Used in Addictive Disorders …
Matched Categories: … Drugs Used in Opioid Dependence ... Drugs Used in Addictive Disorders …
Cinoxate
Approved
Matched Iupac: … 2-ethoxyethyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Matched Mixtures name: … Le Stick A Levres Onybel …
Matched Mixtures name: … Le Stick A Levres Onybel …
Penicillium digitatum
Penicillium digitatum allergenic extract is used in allergenic testing.
Approved
Matched Description: … Penicillium digitatum allergenic extract is used in allergenic testing. …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Matched Mixtures name: … Molds - Mold Mix 4 ... Molds - Mold Mix 4 ... Molds - Mold Mix 4 …
Plasminogen
Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as fibrinolysin - as part of the fibrinolytic pathway that breaks down fibrin blood clots. This pathway is activated when a clot is no longer needed or to prevent a clot from extending beyond...
Approved
Matched Description: … [L34635]
In June 2021, the FDA approved a plasma-derived plasminogen (Ryplazim, human plasminogen-tvmh ... Plasminogen is a pro-enzyme (i.e. a zymogen) which is cleaved to form plasmin - also known as [fibrinolysin ... [A236035] This pathway is activated when a clot is no longer needed or to prevent a clot from extending …
Guanadrel
Guanadrel is an antihypertensive agent and postganglionic adrenergic blocking agent.
Approved
Ethambutol
Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … [L31743] Ethambutol was first described in the literature in 1961. ... Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], ... [A229048] It was developed out of a need for therapies active against isoniazid resistant strains of …
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET …
Matched Mixtures name: … ริมสตาร์ 4 - FDC ... AkuriT-4 TABLET …
Teriflunomide
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and...
Approved
Matched Iupac: … (2Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide …
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting …
Matched Description: … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting …
Meclofenamic acid
A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
Approved
Vet approved
Matched Description: … A non-steroidal anti-inflammatory agent with antipyretic and antigranulation activities. …
Influenza B virus B/Phuket/3073/2013 antigen (UV, formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Influenza B virus B/Phuket/3073/2013 antigen (propiolactone inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the ... A seasonally-specific component of the influenza vaccine. …
Hexachlorophene
A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but much less effective against Gram-negative organisms. It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p797)
Approved
Withdrawn
Matched Description: … A chlorinated bisphenol antiseptic with a bacteriostatic action against Gram-positive organisms, but ... It is mainly used in soaps and creams and is an ingredient of various preparations used for skin disorders …
Cenobamate
Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial onset seizures.[A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively modulates GABAA and inhibits voltage gated sodium channels. Cenobamate was granted FDA approval on 21 November 2019.
Approved
Investigational
Matched Description: … modulates GABAA and inhibits voltage gated sodium channels. ... Cenobamate, or YKP-3089, is an antiepileptic drug developed by SK Pharmaceuticals and used to treat partial ... [A188442,L10653] The exact mechanism of action has not been described in the literature, though it positively …
Phoma exigua var. exigua
Phoma exigua var. exigua is a fungus which can provoke allergic reactions. Phoma exigua var. exigua extract is used in allergenic testing.
Approved
Matched Description: … Phoma exigua var. exigua extract is used in allergenic testing. ... Phoma exigua var. exigua is a fungus which can provoke allergic reactions. …
Matched Mixtures name: … Rinkel Mold Mix A …
Matched Mixtures name: … Rinkel Mold Mix A …
Givosiran
Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical enzyme in the heme biosynthesis pathway. It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic...
Approved
Investigational
Matched Description: … [L10202] It is manufactured by Alnylam Pharmaceuticals and was first approved for use in the United States ... in November 2019 for the treatment of adults with acute hepatic porphyria, a genetic disorder in which ... Givosiran is a small interfering RNA (siRNA) directed towards 5-aminolevulinic acid synthase, a critical …
Avacincaptad pegol
Avacincaptad pegol is an RNA aptamer covalently bound to a branched polyethylene glycol (PEG) molecule. It was developed to treat an advanced form of age-related macular degeneration (AMD) called geographic atrophy (GA). AMD is the leading cause of vision loss in developed countries for people over 50 years old, with...
Approved
Investigational
Matched Description: … [A260801]
Avacincaptag pegol was approved by the FDA on August 4, 2023, under the brand name IZERVAY ... [L47696] AMD is the leading cause of vision loss in developed countries for people over 50 years old, ... with a global estimate of 170 million individuals affected. …
Pentoxifylline
Pentoxifylline (PTX) is a synthetic dimethylxanthine derivative that modulates the rheological properties of blood and also has both anti-oxidant and anti-inflammatory properties.[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for its possible...
Approved
Investigational
Matched Description: … A branded product, PENTOXIL, marketed by Upsher-Smith Laboratories, and generic forms marketed by Valeant ... under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but ... use in diverse conditions, including osteoradionecrosis, diabetic kidney disease, and generally any …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Iothalamic acid
Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Description: … Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Soybean oil
Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. ... major component fatty acids are linoleic (48% - 58%), oleic (17% - 30%), palmitic (9% -13%), linolenic (4% ... Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated …
Vinorelbine
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC .
It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Iupac: … methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10 …
Matched Description: … It is a third-generation vinca alkaloid. ... a strong influence of genetics on the clearance of this drug [L2002]. ... It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Description: … It is a third-generation vinca alkaloid. ... a strong influence of genetics on the clearance of this drug [L2002]. ... It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Displaying drugs 701 - 725 of 15366 in total