Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Displaying drugs 51 - 75 of 8582 in total

Timolol

Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … (S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol …
Matched Mixtures name: … Timpilo 4 ... COSOPT PF OFTALMIK COZELTI, 60 ADET ... COSOPT PF OFTALMIK COZELTI, 60 ADET …
Matched Products: … TİMOCOPT %0,5 GÖZ DAMLASI, ÇÖZELTİ, 60 FLAKON …

Sulfadimethoxine

Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic...
Approved
Vet approved
Withdrawn
Matched Synonyms: … 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide ... 2,6-dimethoxy-4-sulfanilamidopyrimidine ... N(1)-(2,6-Dimethoxy-4-pyrimidinyl)sulfanilamide …
Matched Iupac: … 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide …

Vinflunine

Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death...
Approved
Investigational
Matched Synonyms: … 20',20'-difluoro-3',4'-dihydrovinorelbine ... 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine ... 4'-deoxy-20',20'-difluoro-8'-norvincaleukoblastine …
Matched Iupac: … methyl (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-4-[(1R,12S,14S,16R)-16-(1,1-difluoroethyl)-12-(methoxycarbonyl …
Matched Description: … While these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there …

Amsacrine

Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression...
Approved
Investigational
Matched Synonyms: … 4'-(9-Acridinylamino)methanesulfon-m-anisidide ... 4'-(9-Acridinylamino)-3'-methoxymethanesulfonanilide ... 4'-(9-Acridinylamino)methanesulphon-m-anisidide …
Matched Iupac: … N-{4-[(acridin-9-yl)amino]-3-methoxyphenyl}methanesulfonamide …
Matched Salts cas: … 54301-15-4 …

Levothyroxine

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Synonyms: … 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodo-L-phenylalanine ... O-(4-Hydroxy-3,5-diidophenyl)-3,5-diiodo-L-tyrosine ... O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine …
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid …
Matched Description: … potency of ~1:4 (T4:T3). ... the thyroid gland is no longer able to produce sufficient quantities of the thyroid hormones T4< ... release by the pituitary gland, a normally functioning thyroid gland will produce and secrete T4< …
Matched Mixtures name: … Np Thyroid 60 ... NP Thyroid 60 ... NP Thyroid 60 …

Ospemifene

Ospemifene is a new selective non-hormonal estrogen receptor modulator (SERM) that is used for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. FDA approved on February 26, 2013.
Approved
Investigational
Matched Synonyms: … 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol ... 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol …
Matched Iupac: … 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethan-1-ol …

Iloperidone

Iloperidone is a benzisoxazole and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. It is considered to be a second-generation antipsychotic drug with multiple receptor binding profile, although it shows high affinity towards 5-HT2A and dopamine D2 receptors. Iloperidone is currently used to...
Approved
Matched Synonyms: … 4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenone ... 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone …
Matched Iupac: … 1-(4-{3-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-one …

Metoclopramide

Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to...
Approved
Investigational
Matched Synonyms: … 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide ... 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide ... 4-amino-5-chloro-2-methoxy-N-(β-diethylaminoethyl)benzamide …
Matched Iupac: … 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide …
Matched Products: … METOCLOPRAMIDA 4 MG/ML GOTAS ... METOCLOPRAMIDA 4 MG / ML GOTAS …

Oxilofrine

Oxilofrine is used in combination with DB11609 as an antitussive. It is currently marketed in Canada by Valeant under the tradename Cophylac.
Approved
Matched Synonyms: … 4-HMP ... 4-hydroxyephedrine …
Matched Iupac: … 4-[(1R,2S)-1-hydroxy-2-(methylamino)propyl]phenol …

Ibutilide

Ibutilide is a Class III antiarrhythmic agent available in intravenous formulations. It is indicated for the conversion of acute atrial flutter and recent onset atrial fibrillation to normal sinus rhythm (NSR).
Approved
Matched Synonyms: … N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide …
Matched Iupac: … N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide …

Efavirenz

Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …

Pilocarpine

A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Mixtures name: … Timpilo 4 ... E-pilo-4 Oph Soln ... E-pilo 4 Ophthalmic Solution …
Matched Products: … -carpine 4% ... Pilopine Hs 4% ... Pilocarpine 4% …

Probenecid

The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
Approved
Investigational
Matched Synonyms: … 4-(Di-n-propylsulfamoyl)benzoesäure ... 4-((Dipropylamino)sulfonyl)benzoic acid ... 4-(N,N-Dipropylsulfamoyl)benzoesäure …
Matched Iupac: … 4-(dipropylsulfamoyl)benzoic acid …

Acetaminophen

Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Synonyms: … 4-acetamidophenol ... 4-(Acetylamino)phenol ... 4'-hydroxyacetanilide …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Mixtures name: … GRIPORT 650 MG/4 MG/ 60 MG FILM KAPLI TABLET ,20 ADET ... GRIPIN HOT D 500/4/60 TEK KULLANIMLIK TOZ İÇEREN POŞET, 6 POŞET ... GRIPIN HOT D 500/4/60 TEK KULLANIMLIK TOZ İÇEREN POŞET, 12 POŞET …
Matched Products: … VOLPAN TABLET, 4 ADET ... PANADOL DROPS 60 mg/0.6 ml ... VOLPAN KOMPOZE TABLET, 4 ADET …

Lapatinib

Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Synonyms: … )-4-quinazolinamine ... N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl …
Matched Iupac: … )quinazolin-4-amine ... N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl …

Sulfapyridine

Antibacterial, potentially toxic, and previously used to treat certain skin diseases. No longer prescribed.
Approved
Matched Synonyms: … 4-(2-Pyridinylsulfonyl)aniline ... 4-[(2-Pyridylamino)sulfonyl]aniline ... 4-Amino-N,2-pyridinylbenzenesulfonamide …
Matched Iupac: … 4-amino-N-(pyridin-2-yl)benzene-1-sulfonamide …

Lumefantrine

Lumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including...
Approved
Matched Synonyms: … 2-Dibutylamino-1-[2,7-dichloro-9-(4-chloro-benzylidene)-9H-fluoren-4-yl]-ethanol ... 2-Dibutylamino-1-{2,7-dichloro-9-[1-(4-chloro-phenyl)-meth-(Z)-ylidene]-9H-fluoren-4-yl}-ethanol ... (±)-2,7-Dichloro-9-((Z)-p-chlorobenzylidene)-α-((dibutylamino)methyl)fluorene-4-methanol …
Matched Iupac: … 2-(dibutylamino)-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl]ethan-1-ol …

Phenylbutazone

A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this...
Approved
Vet approved
Matched Synonyms: … 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine ... 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione ... 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione …
Matched Iupac: … 4-butyl-1,2-diphenylpyrazolidine-3,5-dione …

Elafibranor

Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid …

Adapalene

Acne vulgaris is a multifactorial disorder of the pilosebaceous unit involving increased sebum production, inflammation, and hyperproliferation/hyperkeratinization of the follicular infundibulum. It is also associated with Cutibacterium acnes (also known as Propionibacterium acnes). Adapalene is a third-generation topical retinoid used for the treatment of acne vulgaris. Adapalene has similar efficacy...
Approved
Matched Synonyms: … 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid …
Matched Iupac: … 6-[3-(adamantan-1-yl)-4-methoxyphenyl]naphthalene-2-carboxylic acid …
Matched Mixtures name: … Adapalene 0.3% / Niacinamide 4% ... Adapalene 0.3% / Benzoyl Peroxide 2.5% / Niacinamide 4% ... Adapalene 0.1% / Benzoyl Peroxide 2.5% / Niacinamide 4% …
Matched Products: … DIFFERIN % 0.1 JEL, 60 G …

Cariprazine

Cariprazine is an atypical antipsychotic agent and a piperazine derivative that was first developed in Hungary. It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT1A receptors and as an antagonist at serotonin 5-HT2A receptors. Cariprazine has been investigated in a variety of psychiatric disorders,...
Approved
Investigational
Matched Synonyms: … trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochloride …
Matched Iupac: … 3,3-dimethyl-1-[(1r,4r)-4-{2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl}cyclohexyl]urea …

Deferiprone

Deferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired....
Approved
Matched Synonyms: … 1,2-Dimethyl-3-hydroxypyrid-4-one ... 3-Hydroxy-1,2-dimethyl-4(1H)-pyridone …
Matched Iupac: … 3-hydroxy-1,2-dimethyl-1,4-dihydropyridin-4-one …

Norethisterone

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Synonyms: … 17-α-ethynyl-4-estren-17-ol-3-one ... 17α-ethynyl-4-estren-17-ol-3-one ... 17α-ethinylestra-4-en-17β-ol-3-one …

Futibatinib

Futibatinib is an inhibitor of Fibroblast Growth Factor receptor (FGFR), which comprises a group of receptor tyrosine kinases that play a key role in cell proliferation, differentiation, migration, and survival. FGFR was investigated in oncology as a therapeutic target, as FGFR genomic aberrations and dysregulated FGFR signalling pathways are observed...
Approved
Investigational
Matched Synonyms: … 1-((3S)-(4-amino-3-((3,5-dimethoxyphenyl)ethynyl)-1H-pyrazolo(3, 4-d) pyrimidin-1-yl)-1-pyrrolidinyl) ... 1-[(3S)-3-{4-amino-3-[(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl] …
Matched Iupac: … 1-[(3S)-3-{4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pyrazolo[3,4-d]pyrimidin-1-yl}pyrrolidin-1-yl …
Matched Description: … [L43347] On July 4, 2023, the European Commission granted Conditional Marketing Authorization for futibatinib …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Synonyms: … 4-chloro-m-xylenol ... 3,5-dimethyl-4-chlorophenol ... 4-chloro-3,5-dimethylphenol …
Matched Iupac: … 4-chloro-3,5-dimethylphenol …
Displaying drugs 51 - 75 of 8582 in total