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Displaying drugs 51 - 75 of 12454 in total

Heparin

Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular ... monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in …
Matched Mixtures name: … Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose ... Heparin Sodium in Dextrose …
Matched Products: … Heparin Sodium in Dextrose ... Heparin Sodium in Sodium Chloride ... Heparin Sodium In Sodium Chloride …

Acetic acid

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Mixtures name: … Sb-123 ... Sb-111 ... Sb-119 …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Lucinactant

Lucinactant is a new synthetic peptide-containing surfactant for intratracheal use. It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P). More specifically, it mimics the C-terminal amphipathic helical domain of this protein. It also consists of phospholipids...
Approved
Investigational
Matched Description: … More specifically, it mimics the C-terminal amphipathic helical domain of this protein. ... peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P …

Varicella zoster vaccine (live/attenuated)

Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals 12 months of age and older. While the two vaccines contain the same immunological components and provide protection...
Approved
Matched Description: … efficacy in preventing postherpetic neuralgia in patients 70 years and older and 91% efficacy in patients ... Live attenuated zoster vaccine is available as two products: Zostavax for the prevention of shingles in ... immunocompetent people over the age of 50, and Varivax for the prevention of chickenpox in individuals …
Matched Mixtures name: … Priorix - Tetra Pulver in einer Durchstechflasche und Lösungsmittel in einer Fertigspritze zur Herstellung …
Matched Products: … VARIVAX Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze ... Varilrix Pulver und Lösungsmittel zur Herstellung einer Injektionssuspension in einer Fertigspritze …

Benzoic acid

A fungistatic compound that is widely used as a food preservative. It is conjugated to GLYCINE in the liver and excreted as hippuric acid. As the sodium salt form, sodium benzoate is used as a treatment for urea cycle disorders due to its ability to bind amino acids. This leads...
Approved
Investigational
Matched Description: … It is conjugated to GLYCINE in the liver and excreted as hippuric acid. ... This leads to excretion of these amino acids and a decrease in ammonia levels. ... Recent research shows that sodium benzoate may be beneficial as an add-on therapy (1 gram/day) in schizophrenia …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … S Panax All In One Mist …

Oxybuprocaine

Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology and otolaryngology. Oxybuprocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions.
Approved
Investigational
Matched Description: … Oxybuprocaine (also known as Benoxinate) is a local anesthetic, which is used especially in ophthalmology …
Matched Products: … Benoxinat 1% - Lösung zur Anästhesie in der Oto-Rhino-Laryngologie …

Liotrix

Liotrix is a synthetically derived thyroid hormone replacement preparation. It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in a 4 to 1 ratio by weight. Liotrix was developed when it was believed that serum levels of both T4 and T3 were maintained by direct thyroidal secretion....
Approved
Matched Description: … In fact, administration of T3 may result in supratherapeutic levels of T3. ... It consists of levothyroxine sodium (thyroxine, T4) and liothyronine sodium (triiodothyronine, T3) in ... approximately ten times more T4 than T3 and that 80% of serum T3 is derived from deiodination of T4 in …

Hepatitis B Vaccine (Recombinant)

Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis...
Approved
Withdrawn
Matched Description: … It is marketed in Canada as Engerix B. ... In Asia, infection often occurs early in life, leading to a hepatitis B marker prevalence of more than ... A significant reduction in the incidence of hepatocellular carcinoma has been observed in children aged …
Matched Products: … ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 20MCG/ML ... ENGERIX-B SUSPENSION FOR INJECTION IN PREFILLED SYRINGE 10mcg/0.5ml ... ENGERIX-B 20 Mikrogramm/1 ml Injektionssuspension in einer Fertigspritze …

Labetalol

Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Products: … Labetalol HCl in Dextrose ... Labetalol HCl in Sodium Chloride …

Abatacept

Abatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1).[L20504,L42715] Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Matched Description: … It is produced through recombinant DNA technology in mammalian CHO cells. …
Matched Products: … ORENCIA Injection 125mg/ml in Prefilled Syringe …

Gadobenic acid

Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Description: … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based ... [A1139] Gadobenate dimeglumine was approved by the FDA in November 2004 under the brand name MultiHance …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … MultiHance 0,5 mmol/ml Injektionslösung in einer Fertigspritze …

Cinnamon oil

Approved
Experimental
Matched Mixtures name: … AXE BRAND HEAT OIL …

Octreotide

Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. …
Matched Products: … Siroctid 0,1 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,5 mg/ml Injektionslösung in einer Fertigspritze ... Siroctid 0,05 mg/ml Injektionslösung in einer Fertigspritze …

Esmolol

Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate …
Matched Products: … Esmolol Hydrochloride in Water ... Esmolol Hydrochloride In Sodium Chloride …

Ethyl salicylate

Approved
Experimental
Matched Mixtures name: … Deep Heat Sports Pain Relief Spray …

Latamoxef

Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain cephalosporins. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
Approved
Investigational
Matched Description: … Latamoxef is a broad- spectrum beta-lactam antibiotic similar in structure to the cephalosporins except …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Nitroprusside

Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.
Approved
Investigational
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Sodium Nitroprusside In 0.9% Sodium Chloride …

Bivalirudin

Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously. Because it can cause blood stagnation, it is important to monitor changes in...
Approved
Investigational
Matched Description: … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the ... Because it can cause blood stagnation, it is important to monitor changes in hematocrit, activated partial …
Matched Products: … Bivalirudin in 0.9% Sodium Chloride …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … 10 amino acids forming an ester-linked ring and the N-terminal tryptophan covalently bonded to decanoic ... Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal ... [A231374, L32534] Daptomycin was first discovered in the early 1980s by researchers at Eli Lilly in soil …
Matched Products: … Daptomycin in Sodium Chloride …

Exenatide

Exenatide is a glucagon-like peptide-1 (GLP-1) analog . It activates the GLP-1 receptor and increases insulin secretion, decreases glucagon secretion, and slows gastric emptying to improve glycemic control . Exenatide was given FDA approval on April 28, 2005 . It is available as immediate- and extended-release formulations.[L42685,L42690] Bydureon, the brand...
Approved
Investigational
Matched Description: … , was discontinued in 2021. ... [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … BYDUREON POWDER AND SOLVENT FOR PROLONGED-RELEASE SUSPENSION FOR INJECTION IN PRE-FILLED PEN 2MG …

Hyaluronic acid

Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Description: … neural tissues; it was first isolated in 1934. ... Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... HA is involved in many important physiological processes, including but not limited to wound healing, …
Matched Mixtures name: … Le-Blen Vitamin C Serum …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … C-eye Day ... C-eye Night …

Relebactam

Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to avibactam.[A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing a positive charge. It is currently available in a combination product which includes imipenem and cilastatin to treat complicated urinary tract infections (UTIs), pyelonephritis, and complicated...
Approved
Investigational
Matched Description: … [A181195,A181207] It includes a piperidine ring which reduces export from bacterial cells by producing ... Relebactam is a diazabicyclooctane beta-lactamase inhibitor, similar in structure to [avibactam]. ... [A181207] It is currently available in a combination product which includes [imipenem] and [cilastatin …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Bridged-Ring …

Hemoglobin

The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational

Carbenicillin

Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
Approved
Investigational
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Cimetidine in Sodium Chloride ... DYNAMET TABLET 200MG (F/C) …
Displaying drugs 51 - 75 of 12454 in total