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Displaying drugs 726 - 750 of 2136 in total
Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.[L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be...
Approved
Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other...
Approved
Investigational
Matched Iupac: … 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(piperidin-1-yl)-hexadecahydro …
Caspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. It is typically administered intravenously. It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal...
Approved
Matched Products: … AFUNDAS-L 75 MG IV INFUZYON ICIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 FLAKON …
Commonly known as 4-methylbenzylidene-camphor (4-MBC), enzacamene is a camphor derivative and an organic chemical UV-B filter. It is used in cosmetic products such as sunscreen to provide skin protection against UV rays. While its effects on the human reproductive system as an endocrine disruptor are being investigated, its use in...
Approved
Matched Mixtures name: … Sebamed Sun Cream SPF 8 ... Sebamed Sun Lotion SPF 8 ... Soin Solaire Autobronzant SPF 8 - Crm …
Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Mixtures name: … 05 Moisture Foundation SPF 15 ... Ipkn Moist and Firm Bb 05 Medium Tan ... sunbetter Broad Spectrum SPF 75 Sunscreen Tone Smart …
Matched Products: … KATAY LOCION 8% ... CALAPICLOCIÓN 8% ... OXITREX 8% LOCION …
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Salts cas: … 52-28-8 ... 6059-47-8
Matched Mixtures name: … Exdol-8 ... Atasol 8 ... Triatec-8
A pyrazine that is used therapeutically as an antitubercular agent.
Approved
Investigational
Matched Mixtures name: … RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG ... RIFAMPICINA 150 MG+ ISONIAZIDA 75 MG + PIRAZINAMIDA 400 MG+ ETAMBUTOL CLORHIDRATO 275 MG TABLETAS RECUBIERTAS …
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Iupac: … (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic …
An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched Mixtures name: … SulfaCleanse 8/4 ... Sodium Sulfacetamide 8% and Sulfur 4% ... Sodium Sulfacetamide 8% and Sulfur 4% …
Vorapaxar is a tricyclic himbacine-derived selective inhibitor of protease activated receptor (PAR-1) indicated for reducing the incidence of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease (PAD). By inhibiting PAR-1, a thrombin receptor expressed on platelets, vorapaxar prevents thrombin-related platelet aggregation.
Approved
Matched Salts cas: … 705260-08-8
Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Approved
Investigational
Nutraceutical
Matched Salts cas: … 200393-05-1 …
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) …
Peanut allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … PALFORZIA (Level 8) ... PALFORZIA (Level 8) …
Pyrithione zinc, or zinc pyrithione or zinc pyridinethione, is a coordination complex consisted of pyrithione ligands chelated to zinc (2+) ions via oxygen and sulfur centers. In the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat...
Approved
Matched Products: … Sulfur 8 Aqua Blue ... Sulfur 8 Kids Anti-Dandruff ... Sulfur 8 Oil Moisturizer Anti-Dandruff …
Approved
Experimental
Matched Mixtures name: … Racord Two No 8 ... Sil Trax Plus No 8
Carya ovata pollen is the pollen of the Carya ovata plant. Carya ovata pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix ... Eastern 8 Tree Pollen Mix …
Vortioxetine is an antidepressant medication indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and stimulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake...
Approved
Investigational
Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Naxitamab (humanized 3F8, hu3F8) is an IgG1 monoclonal antibody directed against the oncofetal differentiation antigen GD2 disialoganglioside.[L24454,A224604] Normally expressed during fetal development and in mature neurons, pain fibers, and skin cells, GD2 constitutes a highly efficient target in the treatment of neuroblastoma - it is widely expressed across and within...
Approved
Withdrawn from the Canadian, US, and UK markets in 1998 due to genotoxicity.
Approved
Investigational
Withdrawn
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Description: … correlated with an increase of 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% …
Pseudoephedrine is structurally related to ephedrine but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889. The decongestant effect of pseudoephedrine was described...
Approved
Matched Salts cas: … 345-78-8
Matched Mixtures name: … DUACT 8 MG/60 MG KAPSÜL, 30 ADET …
Nimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has...
Approved
Investigational
Withdrawn
Matched Mixtures name: … ETNA COMBO 100 MG/8 MG TABLET, 14 ADET ... NİMES COMBO 100 MG / 8 MG TABLET , 14 ADET …
Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic properties. Its therapeutic effects are due to its ability to inhibit prostaglandin synthesis. It is indicated for relief of signs and symptoms of rheumatoid arthritis and osteoarthritis.
Approved
Investigational
Vet approved
Matched Mixtures name: … ETOTIO 400 MG/8 MG FILM TABLET, 20 ADET ... ETOLAX 500 MG/8 MG FİLM KAPLI TABLET, 14 ADET …
Icosapent ethyl or ethyl eicosapentaenoic acid is a synthetic derivative of the omega-3 fatty acid eicosapentaenoic acid (EPA). It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides. FDA approved on...
Approved
Investigational
Nutraceutical
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Displaying drugs 726 - 750 of 2136 in total