Displaying drugs 776 - 800 of 1031 in total
MRK-003
MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. It is the preclinical analog of MK-0752, a drug in clinical development.
Investigational
Matched Synonyms: … 1-yl]prop-1-enyl]spiro[1,2,5-thiadiazolidine-4,13'-tricyclo[8.2.1.03,8]trideca-3(8),4,6-triene] 1,1-dioxide …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators ... Sulfur Compounds …
Matched Description: … MRK-003 is a potent and selective γ-secretase inhibitor developed by Merck. …
Matched Categories: … Gamma Secretase Inhibitors and Modulators ... Sulfur Compounds …
Hydroxychloroquine
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in...
Approved
Matched Description: … Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. ... the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and ... [A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV …
Matched Salts name: … Hydroxychloroquine sulfate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Hydroxychloroquine Sulfate ... Hydroxychloroquine sulfate ... HYDROXYCHLOROQUINE SULFATE …
Matched Salts name: … Hydroxychloroquine sulfate …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … Hydroxychloroquine Sulfate ... Hydroxychloroquine sulfate ... HYDROXYCHLOROQUINE SULFATE …
Neoarsphenamine
Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …
Paromomycin
An oligosaccharide antibiotic produced by various streptomyces. [PubChem]
Approved
Investigational
Matched Salts name: … Paromomycin sulfate …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Paromomycin Sulfate …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Paromomycin Sulfate …
Hyoscyamine
Hyoscyamine is a tropane alkaloid and the levo-isomer of atropine. It is commonly extracted from plants in the Solanaceae or nightshade family. Research into the action of hyoscyamine in published literature dates back to 1826. Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic...
Approved
Matched Description: … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine]. ... [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Hyoscyamine sulfate ... Hyoscyamine sulfate dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Matched Products: … Hyoscyamine Sulfate ... Hyoscyamine Sulfate SL ... Hyoscyamine sulfate …
Matched Mixtures name: … Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenobarbital, Hyoscyamine Sulfate, Atropine Sulfate and Scopolamine Hydrobromide ... Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Hyoscyamine sulfate ... Hyoscyamine sulfate dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... hyoscyamine and psycholeptics …
Matched Products: … Hyoscyamine Sulfate ... Hyoscyamine Sulfate SL ... Hyoscyamine sulfate …
Fusidic acid
An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Salts name: … Fucidate sodium …
Matched Products: … FUSIDATO DI SODIO ISDIN ... Axcel Sodium Fusidate 250 Tablet ... VAXCEL SODIUM FUSIDATE-500MG INJECTION …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Salts name: … Fucidate sodium …
Matched Products: … FUSIDATO DI SODIO ISDIN ... Axcel Sodium Fusidate 250 Tablet ... VAXCEL SODIUM FUSIDATE-500MG INJECTION …
Durlobactam
Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Synonyms: … (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE ... SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTER …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial …
Matched Salts name: … Durlobactam sodium …
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial …
Matched Salts name: … Durlobactam sodium …
Amikacin
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Description: … of breath and the coughing up of blood. ... some Mycobacterium (M. avium-intracellulare, M. chelonae, and M. fortuitum)[L4680]. ... that it exerts activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and …
Matched Salts name: … Amikacin sulfate …
Matched Categories: … cefepime and amikacin …
Matched Products: … Amikacin Sulfate ... AMIKACIN Sulfate ... AMIKACIN SULFATE …
Matched Salts name: … Amikacin sulfate …
Matched Categories: … cefepime and amikacin …
Matched Products: … Amikacin Sulfate ... AMIKACIN Sulfate ... AMIKACIN SULFATE …
Vinblastine
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Approved
Matched Salts name: … Vinblastine sulfate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Vinblastine Sulfate ... Vinblastine Sulfate Injection ... Vinblastine Sulfate Inj 1mg/ml …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Vinblastine Sulfate ... Vinblastine Sulfate Injection ... Vinblastine Sulfate Inj 1mg/ml …
Aminohippuric acid
The glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity. [PubChem]
Approved
Investigational
Matched Description: … Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory …
Matched Salts name: … Aminohippurate sodium …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries …
Matched Products: … Aminohippurate Sodium Pah ... Aminohippurate Sodium Inj Liq 20% …
Matched Salts name: … Aminohippurate sodium …
Matched Categories: … Benzamides and benzamide derivatives ... Indicators and Reagents ... Tests for Renal Function and Ureteral Injuries …
Matched Products: … Aminohippurate Sodium Pah ... Aminohippurate Sodium Inj Liq 20% …
Nitrous acid
Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Description: … applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and ... Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to …
Matched Salts name: … Sodium nitrite …
Matched Categories: … Diet, Food, and Nutrition ... Indicators and Reagents ... sodium nitrite ... Sodium Compounds …
Matched Products: … Sodium Nitrite ... Sodium Nitrite Injection, USP …
Matched Salts name: … Sodium nitrite …
Matched Categories: … Diet, Food, and Nutrition ... Indicators and Reagents ... sodium nitrite ... Sodium Compounds …
Matched Products: … Sodium Nitrite ... Sodium Nitrite Injection, USP …
Albinterferon Alfa-2B
Albumin-interferon alpha (Albuferon) is a novel, long-acting form of interferon alpha. Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range of cancers. Human Genome Sciences modified interferon alpha to improve its pharmacological properties by using the company's proprietary albumin fusion technology. Human...
Investigational
Matched Synonyms: … alb-IFN …
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Matched Description: … Recombinant interferon alpha is approved for the treatment of hepatitis C, hepatitis B, and a broad range ... In response to an FDA ruling, Novartis and Human Genome Sciences announced on October 5, 2010 that they …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Salts name: … Methohexital sodium …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Brevital Sodium ... Brietal Sodium Ampoule 660 …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … Brevital Sodium ... Brietal Sodium Ampoule 660 …
Hypochlorite
Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. ... Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and ... Hypochlorite is often used as a chemical reagent for chlorination and oxidation reactions. …
Matched Salts name: … Sodium hypochlorite …
Matched Categories: … Antiseptics and Disinfectants ... Chlorine Compounds ... Sodium Compounds ... sodium hypochlorite …
Matched Products: … Sodium hypochlorite disinfectant ... (Qiqing) Sodium Hypochlorite Disinfectant …
Matched Salts name: … Sodium hypochlorite …
Matched Categories: … Antiseptics and Disinfectants ... Chlorine Compounds ... Sodium Compounds ... sodium hypochlorite …
Matched Products: … Sodium hypochlorite disinfectant ... (Qiqing) Sodium Hypochlorite Disinfectant …
Magaldrate
Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Approved
Withdrawn
Matched Synonyms: … Aluminium magnesium hydroxide sulfate hydrate ... Aluminum magnesium hydroxide sulfate hydrate ... Hydrate magnesium aluminate activated sulfate …
Matched Description: … Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and …
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids ... magaldrate and antiflatulents …
Matched Description: … Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and …
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids ... magaldrate and antiflatulents …
Exagamglogene autotemcel
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … Autologous CD34+ cells isolated from mobilised peripheral blood by positive selection, modified by CRISPR ... /Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9) mediated …
Matched Description: … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor ... hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation …
Matched Categories: … Blood and Blood Forming Organs …
Matched Description: … Exagamglogene autotemcel is an autologous CRISPR-Cas9 modified CD34+ human hematopoietic stem and progenitor ... hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and ... [A262691] Treatment options for SCD are largely focused on preventing the production and circulation …
Matched Categories: … Blood and Blood Forming Organs …
Fondaparinux
Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and a O-methyl group at the reducing end of the molecule. It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they are cleaved into monomeric units. The monomeric sequence in heparin and HS...
Approved
Investigational
Matched Description: … It is structurally similar to polymeric glycosaminoglycan heparin and heparan sulfate (HS) when they ... Fondaparinux (Arixtra) is a synthetic anticoagulant agent consisting of five monomeric sugar units and ... The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural …
Matched Salts name: … Fondaparinux sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Fondaparinux Sodium ... FONDAPARINUX SODIUM ... Fondaparinux Sodium Injection …
Matched Salts name: … Fondaparinux sodium …
Matched Categories: … Blood and Blood Forming Organs …
Matched Products: … Fondaparinux Sodium ... FONDAPARINUX SODIUM ... Fondaparinux Sodium Injection …
Liothyronine
Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine with bound iodine. The exogenous liothyronine product was developed...
Approved
Vet approved
Matched Description: … [T457] The exogenous liothyronine product was developed by King Pharmaceuticals and FDA approved in 1956 …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Salts name: … Liothyronine sodium …
Matched Categories: … liothyronine sodium ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... combinations of levothyroxine and liothyronine …
Matched Products: … Liothyronine Sodium ... Liothyronine sodium …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Salts name: … Liothyronine sodium …
Matched Categories: … liothyronine sodium ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... combinations of levothyroxine and liothyronine …
Matched Products: … Liothyronine Sodium ... Liothyronine sodium …
Dipotassium phosphate
Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive as a source of phosphorus and potassium as well as a buffering agent.
Approved
Matched Synonyms: … Phosphoric acid, dipotassium salt ... Phosphoric acid, potassium salt (1:2) …
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Ionosol B and Dextrose ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI …
Matched Categories: … Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …
Matched Description: … as a source of phosphorus and potassium as well as a buffering agent. ... Dipotassium phosphate (K2HPO4) is a highly water-soluble salt often used as a fertilizer and food additive …
Matched Mixtures name: … Ionosol B and Dextrose ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI ... ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKI …
Matched Categories: … Phosphoric Acids ... Phosphorus Acids ... Phosphorus Compounds …
Phenelzine
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Description: … a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and ... [A15753] It was developed by Parke Davis and originally FDA approved on June 9th, 1961. …
Matched Salts name: … Phenelzine sulfate …
Matched Products: … Phenelzine Sulfate ... Nardil Phenelzine Sulfate ... Greenstone Brand Phenelzine Sulfate …
Matched Salts name: … Phenelzine sulfate …
Matched Products: … Phenelzine Sulfate ... Nardil Phenelzine Sulfate ... Greenstone Brand Phenelzine Sulfate …
1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE
Experimental
Matched Name: … 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE …
Dapsone
A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae. Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with pyrimethamine in the treatment of...
Approved
Investigational
Matched Synonyms: … 4-aminophenyl sulfone ... p-aminophenyl sulfone ... bis(4-aminophenyl)sulfone …
Matched Description: … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine ... Sulfur Compounds …
Matched Description: … A sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium …
Matched Categories: … dapsone and rifampicin ... dapsone, rifampicin and clofazimine ... Sulfur Compounds …
Albendazole oxide
Experimental
Matched Synonyms: … Albendazole sulfoxide ... (±)-albendazole sulfoxide …
Displaying drugs 776 - 800 of 1031 in total