Displaying drugs 8201 - 8225 of 9438 in total
Acifluorfen
Acifluorfen is a protoporphyrinogen oxidase inhibitor.
Experimental
Matched Iupac: … 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid …
Methyl undecenoyl leucinate
Methyl undecenoyl leucinate is an active ingredient in whitening creams. It is an α-MSH antagonist that inhibits melanin synthesis and tyrosinase activity and reduces expression of various melanogenic genes.
Experimental
Matched Iupac: … methyl (2S)-4-methyl-2-(undec-10-enamido)pentanoate …
Robenidine
Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden. Despite the availability of other agents to treat coccidiosis, robenidine has been proven to...
Experimental
Vet approved
Matched Iupac: … N,N'-bis[(E)-[(4-chlorophenyl)methylidene]amino]guanidine …
GW-274150
GW274150 has been used in trials studying the treatment and prevention of Asthma, Migraine, Migraine Disorders, and Arthritis, Rheumatoid.
Investigational
Matched Iupac: … (2S)-2-amino-4-[(2-ethanimidamidoethyl)sulfanyl]butanoic acid …
Alaproclate
Alaproclate was developed as one of the first selective serotonin reuptake inhibitor (SSRI) antidepressants by Astra AB (now AstraZeneca) in the 1970s. Development was discontinued due to concerns over hepatotoxicity observed in animal studies. Alaproclate has also been found to act as a non-competitive NMDA receptor antagonist although without discriminative...
Experimental
Matched Iupac: … 1-(4-chlorophenyl)-2-methylpropan-2-yl 2-aminopropanoate …
Clorindione
Clorindione is a vitamin K antagonist, which may be useful to decrease prothrombin levels in humans.
Experimental
Matched Iupac: … 2-(4-chlorophenyl)-2,3-dihydro-1H-indene-1,3-dione …
Zinc orotate
Experimental
Matched Iupac: … zinc(2+) bis(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate) …
Glycyltyrosine
Experimental
Matched Iupac: … (2S)-2-(2-aminoacetamido)-3-(4-hydroxyphenyl)propanoic acid …
Tamibarotene
Tamibarotene is a novel synthetic retinoid for acute promyelocytic leukaemia (APL). Tamibarotene is currently approved in Japan for treatment of recurrent APL, and is undergoing clinical trials in the United States.
Investigational
Matched Iupac: … 4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl]benzoic acid …
Seproxetine
Seproxetine is also known as (S)-norfluoxetine. It is a selective serotonin reuptake inhibitor (SSRI). It is an active metabolite of fluoxetine. Seproxetine was being investigated by Eli Lilly as an antidepressant but development was never completed and the drug was never marketed.
Investigational
Matched Iupac: … (3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine …
β-Methylfentanyl
β-Methylfentanyl is an analgesic of the opioid class. It is an analog of the potent opioid, fentanyl.
Illicit
Matched Iupac: … N-phenyl-N-[1-(2-phenylpropyl)piperidin-4-yl]propanamide …
Nimorazole
Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
Investigational
Matched Iupac: … 4-[2-(5-nitro-1H-imidazol-1-yl)ethyl]morpholine …
Ronifibrate
Experimental
Matched Iupac: … 3-(pyridine-3-carbonyloxy)propyl 2-(4-chlorophenoxy)-2-methylpropanoate …
Dexchlorpheniramine
Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. It is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine...
Experimental
Investigational
Matched Iupac: … [(3S)-3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Batabulin
Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients).
Investigational
Matched Iupac: … 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzene-1-sulfonamide …
Zoliflodacin
Zoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
Investigational
Matched Iupac: … (4'R,6'S,7'S)-17'-fluoro-4',6'-dimethyl-13'-[(4S)-4-methyl-2-oxo-1,3-oxazolidin-3-yl]-5',15'-dioxa-2' …
D-Levofloxacin
A synthetic fluoroquinolone (FLUOROQUINOLONES) antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
Experimental
Matched Iupac: … (2R)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.0^{5,13}]trideca-5,7,9 …
CHROMOPHORE (HIS-TYR-GLY)
Experimental
Matched Iupac: … 2-{2-[(1S)-1-amino-2-(1H-imidazol-5-yl)ethyl]-5-hydroxy-4-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl] …
Puromycin
Puromycin is an antibiotic that prevents bacterial protein translation. It is utilized as a selective agent in laboratory cell cultures. Puromycin is toxic to both prokaryotic and eukaryotic cells, resulting in significant cell death at appropriate doses.
Experimental
Matched Iupac: … (2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)-9H-purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3 ... -yl]-3-(4-methoxyphenyl)propanamide …
Radezolid
Radezolid has been used in trials studying the treatment of Abscess, Bacterial Skin Diseases, Streptococcal Infections, Infectious Skin Diseases, and Staphylococcal Skin Infections, among others.
Investigational
Matched Iupac: … N-{[(5S)-3-[2-fluoro-4'-({[(1H-1,2,3-triazol-5-yl)methyl]amino}methyl)-[1,1'-biphenyl]-4-yl]-2-oxo-1,3 ... -oxazolidin-5-yl]methyl}acetamide …
Matched Salts cas: … 869884-77-5 …
Matched Salts cas: … 869884-77-5 …
Displaying drugs 8201 - 8225 of 9438 in total