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Displaying drugs 801 - 825 of 5231 in total
Dosulepin
Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Synonyms: … 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin ... (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. ... Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... , and New Zealand. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. ... Dosulepsin is a thio derivative of [DB00321] with a similar efficacy to that of [DB00321], and also exhibits ... , and New Zealand. …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Gatifloxacin
Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. It was first introduced by Bristol-Myers Squibb in 1999 under the brand name Tequin® for the treatment of respiratory tract infections. Gatifloxacin is available as...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-cyclopropyl-6-fluoro- 8-methoxy-7-(3-methylpiperazin-1-yl)- 4-oxo-quinoline-3-carboxylic acid ... 1-Cyclopropyl-1,4-dihydro-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Salts cas: … 404858-36-2 ... 180200-66-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Matched Iupac: … 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Gatifloxacin is an antibiotic agent and a member of the fourth-generation fluoroquinolone family. ... It works by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. ... Gatifloxacin is available as tablets and in various aqueous solutions for intravenous therapy. …
Matched Salts cas: … 404858-36-2 ... 180200-66-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Compounds used in a research, industrial, or household setting …
Natalizumab
Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Description: … Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. ... [L48041] Natalizumab was approved by the European Commission on September 22, 2023.[L49096] ... [L48041] While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Sapropterin
Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. It is also essential in the conversion of phenylalanine to tyrosine by the enzyme phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and conversion of tryptophan to 5-hydroxytryptophan via tryptophan hydroxylase.
Approved
Investigational
Matched Synonyms: … 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)-pteridinone ... (−)-(6R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(3H)-pteridinone …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. ... phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Matched Iupac: … (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one …
Matched Description: … Sapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide. ... phenylalanine-4-hydroxylase; the conversion of tyrosine to L-dopa by the enzyme tyrosine hydroxylase; and …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products …
Moricizine
An antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Approved
Investigational
Withdrawn
Matched Synonyms: … ethyl 10-(3-morpholinopropionyl)phenothiazine-2-carbamate ... [10-(3-Morpholin-4-yl-propionyl)-10H-phenothiazin-2-yl]-carbamic acid ethyl ester ... ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamate …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Matched Iupac: … ethyl N-{10-[3-(morpholin-4-yl)propanoyl]-10H-phenothiazin-2-yl}carbamate …
Matched Categories: … Heterocyclic Compounds, 3-Ring …
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3- …
Matched Iupac: … octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3- …
Matched Description: … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. ... Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Salts cas: … 192927-63-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3- …
Matched Description: … Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. ... Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Salts cas: … 192927-63-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Naltrexone
Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Description: … It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and ... The FDA has approved naltrexone for the treatment of alcohol dependence. …
Matched Salts cas: … 16676-29-2 …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Matched Salts cas: … 16676-29-2 …
Matched Mixtures name: … Naltrexone Hydrochloride and Bupropion Hydrochloride Extended-Release …
Matched Categories: … Alimentary Tract and Metabolism ... oxycodone and naltrexone ... bupropion and naltrexone …
Polydatin
Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline structure. While it is isolated from the bark of Picea sitchensis or Polygonum cuspidatum, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products and many daily diets...
Approved
Matched Synonyms: … trans-resveratrol 3-β-glucoside ... resveratrol-3-O-b-mono-D-glucoside ... trans-resveratrol 3-β-D-glucoside …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …
Matched Iupac: … (2S,3R,4S,5S,6R)-2-{3-hydroxy-5-[(1E)-2-(4-hydroxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3,4,5 …
Matched Description: … Polydatin, or Piceid, is a natural precursor and glycoside form of resveratrol with a monocrystalline ... It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis ... Polydatin possesses anti-inflammatory, immunoregulatory, anti-oxidative and anti-tumor activities. …
Dextroamphetamine
Dextroamphetamine is the dextrorotatory enantiomer of amphetamine . Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder[L6010,Label].
Approved
Illicit
Matched Synonyms: … (S)-1-phenyl-2-propylamine ... (S)-1-phenyl-2-aminopropane …
Matched Iupac: … (2S)-1-phenylpropan-2-amine …
Matched Description: … Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity …
Matched Mixtures name: … Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Iupac: … (2S)-1-phenylpropan-2-amine …
Matched Description: … Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity …
Matched Mixtures name: … Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product ... Mixed Salts of a Single-Entity Amphetamine Product …
Matched Categories: … Psychostimulants, Agents Used for ADHD and Nootropics …
Tasimelteon
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of...
Approved
Investigational
Matched Synonyms: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Iupac: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Description: … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour ... In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle ... and can lead to progressively delayed sleep onset. …
Matched Categories: … Hypnotics and Sedatives ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Description: … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour ... In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle ... and can lead to progressively delayed sleep onset. …
Matched Categories: … Hypnotics and Sedatives ... Heterocyclic Compounds, 2-Ring …
Trastuzumab
Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … cancer, where there is a proven amplification of the HER-2 oncogene or over-expression of the HER-2 ... [L14015] It is used as a treatment of human epidermal growth factor receptor (HER)-2+ metastatic breast ... Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and …
Matched Categories: … HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Categories: … HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors ... Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Lactic acid
A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Synonyms: … 2-Hydroxypropanoic acid ... 2-Hydroxypropionic acid ... (±)-2-hydroxypropanoic acid …
Matched Iupac: … 2-hydroxypropanoic acid …
Matched Description: … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Salts cas: … 72-17-3 …
Matched Mixtures name: … Lactate 1-2-3 Injection ... PERI SOLUTION A ... CAPD 3 PERITONEAL DIAYLSIS SOLUTION …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 2-hydroxypropanoic acid …
Matched Description: … Lactic acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved ... (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Salts cas: … 72-17-3 …
Matched Mixtures name: … Lactate 1-2-3 Injection ... PERI SOLUTION A ... CAPD 3 PERITONEAL DIAYLSIS SOLUTION …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Ondansetron
A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ondansetron has...
Approved
Withdrawn
Matched Iupac: … 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-2,3,4,9-tetrahydro-1H-carbazol-4-one …
Matched Description: … A competitive serotonin type 3 receptor antagonist. ... Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ... ondansetron has demonstrated a long history of use and efficacy. …
Matched Categories: … Antiemetics and Antinauseants ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Matched Description: … A competitive serotonin type 3 receptor antagonist. ... Having been developed in the 1980s by GlaxoSmithKline and approved by the US FDA since January 1991, ... ondansetron has demonstrated a long history of use and efficacy. …
Matched Categories: … Antiemetics and Antinauseants ... Heterocyclic Compounds, 3-Ring ... Serotonin 3 Receptor Antagonists …
Matched Products: … Ondansetron and Dextrose ... Ondansetron Hydrochloride and Dextrose ... Ondansetron hydrochloride and dextrose …
Daunorubicin
A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Approved
Matched Synonyms: … (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11 …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Matched Description: … A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others ... , used in treatment of leukemia and other neoplasms. …
Matched Salts cas: … 371770-68-2 …
Matched Categories: … cytarabine and daunorubicin ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Anthracyclines and Related Substances ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Antineoplastic and Immunomodulating Agents …
Matched Products: … AL DAUNO® 20MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Matched Iupac: … (8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy …
Matched Description: … A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others ... , used in treatment of leukemia and other neoplasms. …
Matched Salts cas: … 371770-68-2 …
Matched Categories: … cytarabine and daunorubicin ... BSEP/ABCB11 Substrates with a Narrow Therapeutic Index ... Anthracyclines and Related Substances ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Antineoplastic and Immunomodulating Agents …
Matched Products: … AL DAUNO® 20MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE …
Temoporfin
Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Approved
Investigational
Matched Iupac: … (23),12,14,16,18(21),19-decaen-2-yl]phenol ... 3-[7,12,17-tris(3-hydroxyphenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,11 …
Matched Description: … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Description: … Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Stiripentol
Stiripentol is an antiepileptic agent that is an aromatic allylic alcohol drug, which makes it structurally unique from other antiepileptic drugs.[A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the drug's potent inhibitory effects on hepatic cytochrome P450 (CYP) enzymes. However, its clinical efficacy as...
Approved
Matched Synonyms: … 1-(1,3-Benzodioxol-5-yl)-4,4-dimethyl-1-penten-3-ol ... 4,4-Dimethyl-1-((3,4-methylenedioxy)phenyl)-1-penten-3-ol …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Description: … [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated ... [A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the …
Matched Iupac: … (1E)-1-(2H-1,3-benzodioxol-5-yl)-4,4-dimethylpent-1-en-3-ol …
Matched Description: … [A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated ... [A19740, A250825] The clinical development and marketing of stiripentol were first delayed due to the …
Brivudine
Brivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Approved
Investigational
Matched Synonyms: … (E)-5-(2-Bromovinyl)-deoxyuridine …
Matched Iupac: … 5-[(1E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Matched Description: … Although not approved in the U.S. or Canada, it is approved in several European countries. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Iupac: … 5-[(1E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine …
Matched Description: … Although not approved in the U.S. or Canada, it is approved in several European countries. …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Bazedoxifene
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Iupac: … 1-({4-[2-(azepan-1-yl)ethoxy]phenyl}methyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol …
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the ... Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer …
Matched Salts cas: … 198481-33-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the ... Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer …
Matched Salts cas: … 198481-33-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Acamprosate
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). …
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid …
Matched Description: … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). …
Decitabine
Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Synonyms: … 4-amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-s-triazin-2(1H)-one ... 5-aza-2'-deoxycytidine …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Description: … approved by the FDA for the treatment of MDS on February 5, 2006. ... Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Iupac: … 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Description: … approved by the FDA for the treatment of MDS on February 5, 2006. ... Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Synonyms: … 3-(α-L-rhamnopyranosyloxy)-1β,5β,11α,14,19-pentahydroxy-5β-card-20(22)-enolide …
Matched Iupac: … yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... ,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2- …
Matched Description: … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus ... gratus and other plants of the Apocynaceae; used like digitalis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... ,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2- …
Matched Description: … A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus ... gratus and other plants of the Apocynaceae; used like digitalis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Lomustine
An alkylating agent of value against both hematologic malignancies and solid tumors.
Approved
Investigational
Matched Synonyms: … 1-(2-chloroethyl)-3-cyclohexylnitrosourea ... 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea ... N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea …
Matched Iupac: … 3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea …
Matched Description: … An alkylating agent of value against both hematologic malignancies and solid tumors. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 3-(2-chloroethyl)-1-cyclohexyl-3-nitrosourea …
Matched Description: … An alkylating agent of value against both hematologic malignancies and solid tumors. …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Fluoxetine
Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI). It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies.
Approved
Vet approved
Matched Synonyms: … (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Description: … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor ... [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Matched Iupac: … methyl({3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl})amine …
Matched Description: … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor ... [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of …
Matched Mixtures name: … TARGET 3 MG /25 MG KAPSUL, 90 ADET ... TARGET 3 MG /25 MG KAPSUL, 30 ADET ... FLUXOPIN 3 MG/25 MG KAPSÜL ,30 KAPSÜL …
Matched Categories: … fluoxetine and psycholeptics ... Metabolic Side Effects of Drugs and Substances …
Dacarbazine
An antineoplastic agent. It has significant activity against melanomas. (from Martindale, The Extra Pharmacopoeia, 31st ed, p564). Dacarbazine with Oblimersen is in clinical trials for the treatment of malignant melanoma.
Approved
Investigational
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic Index …
Matched Products: … TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Matched Products: … TREXTECH® 200 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIÓN INYECTABLE …
Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen
Approved
Matched Synonyms: … Nimenrix component neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen …
Matched Name: … Neisseria meningitidis group A capsular polysaccharide tetanus toxoid conjugate antigen …
Displaying drugs 801 - 825 of 5231 in total