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Displaying drugs 851 - 875 of 1184 in total

Phenylbutyric acid

Phenylbutyric acid is a fatty acid and a derivative of butyric acid naturally produced by colonic bacteria fermentation. It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting as a chemical chaperone. It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders.[L386,L42105]
Approved
Investigational
Matched Description: … It demonstrates a number of cellular and biological effects, such as relieving inflammation and acting ... Phenylbutyric acid is a fatty acid and a derivative of [butyric acid] naturally produced by colonic bacteria ... [A249035] It is used to treat genetic metabolic syndromes, neuropathies, and urea cycle disorders. …
Matched Salts name: … Sodium phenylbutyrate …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... sodium phenylbutyrate …
Matched Products: … Sodium Phenylbutyrate …

benzyl (2-oxopropyl)carbamate

Experimental
Matched Name: … benzyl (2-oxopropyl)carbamate …
Matched Iupac: … benzyl N-(2-oxopropyl)carbamate …

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved
Matched Salts name: … Cloxacillin sodium ... Cloxacillin sodium hydrate …
Matched Products: … CLOXACILLINA SODICA ... Cloxacillin Sodium for Injection ... Cloxacillin Sodium Sterile Inj 250mg/vial …

anti-alpha5Beta1-integrin antibody

Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation and migration. The integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody inhibits angiogenesis, including vessel formation induced by vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), as well...
Investigational
Matched Name: … anti-alpha5Beta1-integrin antibody …
Matched Description: … and migration. ... Integrins are important adhesion molecules that regulate tumor and endothelial cell survival, proliferation ... integrin alpha5beta1 has been shown to play a critical role during angiogenesis. anti-alpha5beta1 integrin antibody …

Humanized monoclonal antibody Hu11E6

Investigational
Matched Synonyms: … Humanized monoclonal antibody Hu11E6 …
Matched Name: … Humanized monoclonal antibody Hu11E6 …

Neoarsphenamine

Investigational
Withdrawn
Matched Synonyms: … Sodium p,p'-dihydroxy-m,m'-diaminoarsenobenzene-n-monomethanol sulfoxylate ... Sulfoxylic acid, mono(((5-((3-amino-4-hydroxyphenyl)diarsenyl)-2-hydroxyphenyl)amino)methyl) ester, sodium …
Matched Iupac: … sodium {[({5-[(1E)-2-(3-amino-4-hydroxyphenyl)diarsen-1-yl]-2-hydroxyphenyl}amino)methoxy]sulfanyl}olate …

Tobramycin

Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and ... [A232294, A232299, L32739] However, tobramycin can also be administered intravenously and topically to ... L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and …
Matched Mixtures name: … Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone ... Tobramycin and Dexamethasone …
Matched Products: … Tobramycin in Sodium Chloride …

Foscarnet

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Salts name: … Foscarnet sodium …
Matched Products: … Foscarnet Sodium …

Lactulose

Lactulose is a synthetic disaccharide derivative of lactose that is most commonly used as a laxative agent despite also being formally indicated to serve as an adjunct therapy in treating portal-systemic encephalopathy (PSE).[FDA Label,L6199,L6202] Despite being first synthesized in 1929 , investigations regarding its possible use as a laxative for...
Approved
Matched Description: … possible use as a laxative for the treatment of chronic constipation did not occur until the 1960s and ... [L6202] Nevertheless, although lactulose received formal FDA approval in 1977 and has since become ... List of Essential Medicines as one of the most effective and safe medicines employed in a health system …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … AVELAC ORAL SOLUTION 667mg/ml ... Duphalac Fruit 667 mg/ml - Lösung zum Einnehmen …

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS ... to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and ... to slow the rate of progression of renal disease in hypertensive individuals with diabetes mellitus and …
Matched Mixtures name: … Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide ... Fosinopril Sodium and Hydrochlorothiazide …
Matched Salts name: … Fosinopril sodium …
Matched Categories: … ACE Inhibitors and Diuretics ... Amino Acids, Peptides, and Proteins ... fosinopril and diuretics …
Matched Products: … Fosinopril Sodium ... Fosinopril sodium …

Theobroma cacao whole

Theobroma cacao, whole, allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Cacao sativa whole ... Theobroma sativum whole …

Ampicillin

Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Approved
Vet approved
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium …
Matched Salts name: … Ampicillin sodium …
Matched Products: … Ampicillin Sodium ... AMPICILLIN SODIUM ... AMPICILLINA SODICA …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Salts name: … Rabeprazole sodium …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... rabeprazole, amoxicillin and metronidazole ... rabeprazole, amoxicillin and clarithromycin …
Matched Products: … Rabeprazole sodium ... Rabeprazole Sodium ... Rabeprazole Sodium DR …

Silicon dioxide

Silicon dioxide, or silica, is an oxide of silicon with the chemical formula SiO2. It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite as transparent and tasteless crystals. Inhalation of fine crystals is toxic to humans leading to respiratory toxicity. In powdered food products...
Approved
Matched Description: … In powdered food products and pharmaceutical tablets, silicon dioxide is added as a flow agent to absorb ... as transparent and tasteless crystals. ... It is found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite …
Matched Mixtures name: … Calcium and Magnesium 1:1 Plus Tablets ... Men's Biomultiple Vitamin and Mineral Supplement ... Women's Biomultiple Vitamin and Mineral Supplement …
Matched Products: … Chlorine Dioxide Air Sterilization Card …

Sulfadiazine

One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Approved
Investigational
Vet approved
Matched Description: … combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and …
Matched Salts name: … Sulfadiazine sodium …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sulfonamides and trimethoprim ... sulfadiazine and tetroxoprim ... sulfadiazine and trimethoprim ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sulfadiazine Sodium …

Chlorpheniramine

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Mixtures name: … Ed Chlorped D ... Top Value Effervescent Cold Relief ... Top Value Effervescent Cold Relief - Orange …
Matched Products: … Ed Chlorped ... Ed Chlorped Jr ... CHLORMINE SYRUP 4MG/5ML …

Bromfenac

Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. Non-ophthalmic formulations of bromfenac were...
Approved
Withdrawn
Matched Description: … Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. ... Their well-characterized anti-inflammatory activity, analgesic property, and established safety record …
Matched Salts name: … Bromfenac sodium …
Matched Products: … Bromfenac Sodium …

Daptomycin

Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant Staphylococcus aureus (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE).[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked...
Approved
Investigational
Matched Description: … with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and ... -resistant _Staphylococcus aureus_ (MSSA/MRSA) and vancomycin-resistant Enterococci (VRE). ... A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Daptomycin in Sodium Chloride …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride …

Edetate calcium disodium anhydrous

Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores of lead from the body. It is on the World Health Organization Model List of Essential Medicines. Edetate calcium disodium was granted FDA approval on 16 July 1953.
Approved
Matched Description: … Edetate calcium disodium is a metal ion chelator used to reduce blood concentrations and depot stores …
Matched Categories: … Diet, Food, and Nutrition ... Iron Chelating Agents ... Iron Chelating Activity …
Matched Products: … Calcium Edetate de Sodium …

Methylprednisolone hemisuccinate

A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Approved
Matched Description: … A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies. …
Matched Salts name: … Methylprednisolone sodium succinate …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Methylprednisolone Sodium Succinate ... METHYLPREDNISOLONE SODIUM SUCCINATE ... Methylprednisolone sodium succinate …

humanized SMART Anti-IL-12 Antibody

The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized antibodies being developed for the treatment of autoimmune diseases. SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together with certain intellectual property related to anti-IL-12 therapy, from Hoffmann-La...
Investigational
Matched Name: … humanized SMART Anti-IL-12 Antibody …
Matched Description: … SMART Anti-IL-12 Antibody was humanized at PDL from a murine anti-IL-12 antibody that was licensed, together ... The humanized anti-IL-12 antibody is an important addition to PDL's already strong pipeline of humanized …

Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol)

Approved
Matched Synonyms: … 1,2-dipalmitoyl-sn-glycero-3-phosphorylglycerol sodium salt …
Matched Name: … Sodium 1,2-Dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) …
Matched Iupac: … sodium (2R)-1-[(2,3-dihydroxypropyl phosphono)oxy]-3-(hexadecanoyloxy)propan-2-yl hexadecanoate …

NEO-212

Investigational
Matched Synonyms: … Tmz-poh carbamate ... (s)-perillyl alcohol temozolomide carbamate …
Matched Iupac: … -2-yl)cyclohex-1-en-1-yl]methyl N-{3-methyl-4-oxo-3H,4H-imidazo[4,3-d][1,2,3,5]tetrazine-8-carbonyl}carbamate …

Anti-GD2 monoclonal antibody 3F8

Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy in Treating Patients With Neuroblastoma That Has Not Responded to Previous Treatment).
Investigational
Matched Synonyms: … MONOCLONAL ANTIBODY 3F8 ... ANTI-GD2 MOUSE MONOCLONAL ANTIBODY 3F8 (IGG3) …
Matched Name: … Anti-GD2 monoclonal antibody 3F8 …
Matched Description: … Anti-GD2 monoclonal antibody 3F8 is under investigation in clinical trial NCT00089258 (Biological Therapy …
Displaying drugs 851 - 875 of 1184 in total