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Displaying drugs 76 - 100 of 11935 in total
Alclofenac is a non-steroidal anti-inflammatory drug. It was withdrawn from the market in the United Kingdom in 1979.
Approved
Withdrawn
Matched Synonyms: … 3-Chloro-4-(2-propenyloxy)benzeneacetic acid ... (4-Allyloxy-3-chlorphenyl)essigsäure ... [4-(allyloxy)-3-chlorophenyl]acetic acid …
Matched Iupac: … 2-[3-chloro-4-(prop-2-en-1-yloxy)phenyl]acetic acid …
Matched Categories: … Non COX-2 selective NSAIDS …
A synthetic anabolic steroid used for treating men with testosterone deficiency or similar androgen replacement therapies. Also, has antineoplastic properties and so has been used secondarily in women with advanced breast cancer. Methyltestosterone is a schedule III drug in the US.
Approved
Matched Synonyms: … 17α-methyl-Δ4-androsten-17β-ol-3-one ... 17-beta-Hydroxy-17-methylandrost-4-en-3-one ... 17alpha-Methyl-3-oxo-4-androsten-17beta-ol …
Matched Iupac: … (1S,3aS,3bR,9aR,9bS,11aS)-1-hydroxy-1,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H …
Matched Categories: … 3-Oxoandrosten (4) Derivatives …
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … (17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime ... d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oxime ... (+)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime acetate (ester) …
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate ... (1R,3aS,3bR,7E,9aR,9bS,11aS)-11a-ethyl-1-ethynyl-7-(hydroxyimino)-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … N-[2-(5-methoxyindol-3-yl)ethyl]acetamide …
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Mellozzan 1 mg Tabletten ... Voquily 1 mg/ml Lösung zum Einnehmen ... Mellozzan 2 mg Tabletten …
Ibrutinib is a small molecule that acts as an irreversible potent inhibitor of Burton's tyrosine kinase. It is designated as a targeted covalent drug and presented as a promising activity in B-cell malignancies in clinical trials. Ibrutinib was developed by Pharmacyclics Inc and was first approved by the FDA in...
Approved
Matched Synonyms: … 1-[(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Iupac: … 1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Penicillamine is a pharmaceutical of the chelator class. The pharmaceutical form is D-penicillamine, as L-penicillamine is toxic (it inhibits the action of pyridoxine). It is an α-amino acid metabolite of penicillin, although it has no antibiotic properties.
Approved
Matched Synonyms: … (S)-2-amino-3-mercapto-3-methylbutanoic acid ... 3-mercapto-D-valine …
Matched Iupac: … (2S)-2-amino-3-methyl-3-sulfanylbutanoic acid …
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Synonyms: … RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea …
Matched Iupac: … 1-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-3,3-diethylurea …
Matched Categories: … Adrenergic beta-2 Receptor Agonists ... Adrenergic beta-3 Receptor Agonists ... Adrenergic beta-1 Receptor Antagonists …
Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Synonyms: … N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide …
Matched Iupac: … N-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … LIMEXID 2 MG/1 ML I.V. INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET ... INFÜZYON ÇÖZELTISI,300 ML (1 TORBA) ... ZYVOXID 2MG/ML ENFÜZYON SOLÜSYONU, 1 ADET …
Mesuximide (or methsuximide) is an anticonvulsant medication. It is sold by Pfizer under the name Petinutin.
Approved
Matched Synonyms: … N,2-Dimethyl-2-phenylsuccinimide ... 1,3-Dimethyl-3-phenylsuccinimide ... 1,3-Dimethyl-3-phenyl-2,5-dioxopyrrolidine …
Matched Iupac: … 1,3-dimethyl-3-phenylpyrrolidine-2,5-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Amiloxate is an EMA-approved chemical UV-filter found in over-the-counter sunscreen products at concentrations up to 10%m . It is often referred to as isoamyl 4-methoxycinnamate or isoamyl p-methoxycinnamate. Amiloxate is a cinnamic acid derivative with an anti-inflammatory activity .
Approved
Matched Synonyms: … 3-(4-Methoxyphenyl)-2-propenoic acid, 3-methylbutyl ester …
Matched Iupac: … 3-methylbutyl (2E)-3-(4-methoxyphenyl)prop-2-enoate …
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Synonyms: … (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … Linagliptin was approved by the FDA on May 2, 2011[L9557]. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Solriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated with narcolepsy or obstructive sleep apnea[FDA Label]. Solriamfetol was given FDA approval in 2019[FDA Label].
Approved
Matched Synonyms: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Iupac: … (2R)-2-amino-3-phenylpropyl carbamate …
Matched Categories: … MATE 1 Substrates …
Approved
Experimental
Matched Synonyms: … Ethyl 4'-hydroxy-3'-methoxycinnamate …
Matched Iupac: … ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate …
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol ... 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … A cardioselective beta-1-adrenergic antagonist with no partial agonist activity. …
Matched Categories: … Adrenergic beta-1 Receptor Antagonists …
A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Approved
Matched Synonyms: … (5'α)-12'-hydroxy-2'-methyl-5'-(phenylmethyl)ergotoman-3',6',18-trione ... 12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione ... 12'-Hydroxy-2'-methyl-5'alpha-(phenylmethyl)ergotaman-3',6',18-trione …
Matched Iupac: … (4R,7R)-N-[(1S,2S,4R,7S)-7-benzyl-2-hydroxy-4-methyl-5,8-dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}] ... dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaene …
Matched Description: … It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders …
Matched Salts cas: … 379-79-3
Matched Mixtures name: … ERGOTAMINA/CAFEINA 1/100 MG ... CAFERGOT 1 MG/100 MG TABLET, 30 ADET ... ERGOTAMINA 1 MG + CAFEINA 100 MG TABLETAS …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Synonyms: … 4-Methyl-3-(2-morpholinoethylamino)-6-phenylpyridazin ... 4-(2-((4-Methyl-6-phenyl-3-pyridazinyl)amino)ethyl)morpholine ... N-(4-Methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine …
Matched Iupac: … 4-methyl-N-[2-(morpholin-4-yl)ethyl]-6-phenylpyridazin-3-amine …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Synonyms: … 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide ... 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone ... 7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide …
Matched Iupac: … 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Bimatoprost, also known as Latisse or Lumigan, belongs to a group of drugs called prostamides, which are synthetic structural analogs of prostaglandin. Bimatoprost, marketed by Allergan, is administered in both the ophthalmic solution and implant form. It has the ability to reduce ocular hypotension, proving effective in conditions such as...
Approved
Investigational
Matched Synonyms: … (Z)-7-((1R,2R,3R,5S)-3,5-Dihydroxy-2-((1E,3S)-3-hydroxy-5-phenyl-1-pentenyl)cyclopentyl)-N-ethyl-5-heptenamide …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept …
Matched Mixtures name: … GANFORT % 0,03 + % 0,5 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BEMATORİN-T 0,3 MG + 5 MG/1 ML GÖZ DAMLASI, ÇÖZELTİ, 1 ADET ... BİMASOPT %0.03+%0.5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Products: … BEMATORIN %0.03 GÖZ DAMLASI,3 ML ... LUMIGAN % 0,03 GÖZ DAMLASI, ÇÖZELTİ, 3 ML ... BIMAPRESS 0.3 GÖZ DAAMLASI, 1 ADET …
Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. It acts as an atypical class III antiarrhythmic drug that potentiates its effect in higher heart rates. Intravenous formulation was approved in Europe in September 2010 as Brinavess and...
Approved
Investigational
Matched Synonyms: … (3R)-1-((1R,2R)-2-(2-(3,4-dimethoxyphenyl)ethoxy)cyclohexyl)pyrrolidin-3-ol …
Matched Iupac: … (3R)-1-[(1R,2R)-2-[2-(3,4-dimethoxyphenyl)ethoxy]cyclohexyl]pyrrolidin-3-ol …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Synonyms: … Vitamin D-2 ... (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- ... 4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol …
Matched Mixtures name: … Cal/mag 2:1 With D ... Calcium Magnesium 2:1 Tablets With Vitamin D ... Mvc 9 Plus 3 Inj …
Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Synonyms: … isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate ... 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-β-methoxyethyl ester 5-isopropyl ... isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate …
Matched Iupac: … 3-(2-methoxyethyl) 5-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … NIMOTOP 50 MG/ML INFUZYON COZELTISI, 1 ADET …
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Synonyms: … (2R)-2-acetylamino-3-sulfanylpropanoic acid ... (R)-2-acetylamino-3-mercaptopropanoic acid …
Matched Iupac: … (2R)-2-acetamido-3-sulfanylpropanoic acid …
Matched Products: … FLUIMUCIL® 2% ... HYSTIN SOLUCIONORAL 2 % ... N-ACETILCISTEÍNA 2 G / 100 ML JARABE …
Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic leukemia (CLL), relapsed follicular B-cell non-Hodgkin lymphoma (FL), and relapsed small lymphocytic lymphoma (SLL). For the treatment of relapsed CLL, it is currently indicated as a second-line agent in combination with rituximab in patients for whom rituximab...
Approved
Matched Synonyms: … 5-Fluoro-3-phenyl-2-((S)-1-(9H-purin-6-ylamino)-propyl)-3H-quinazolin-4-one ... 5-fluoro-3-phenyl-2-[(1S)-1-(3H-purin-6-ylamino)propyl]quinazolin-4(3H)-one …
Matched Iupac: … 5-fluoro-3-phenyl-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-3,4-dihydroquinazolin-4-one …
Matched Description: … Idelalisib is a phosphoinositide 3-kinase inhibitor indicated in the treatment of chronic lymphocytic ... specifically, idelalisib targets P110δ, the delta isoform of the enzyme phosphatidylinositol-4,5-bisphosphate 3- …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Phosphatidylinositol-3-kinase (Pi3K) inhibitors ... Class Ia Phosphatidylinositol 3-Kinase, antagonists & inhibitors …
Amikacin is a semi-synthetic aminoglycoside antibiotic that is derived from kanamycin A.[FDA label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1 amino group of the deoxystreptamine moiety of kanamycin A. Amikacin's unique property is that it exerts activity against more resistant gram-negative bacilli such as...
Approved
Investigational
Vet approved
Matched Synonyms: … -D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE ... -D-GLUCOPYRANOSYL-(1->4))-N(SUP 1)-(4-AMINO-2-HYDROXY-1-OXOBUTYL)-2-DEOXY-, (S)- ... O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA. …
Matched Iupac: … oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl ... ]-2-hydroxybutanamide ... (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl) …
Matched Description: … label] Amikacin is synthesized by acylation with the l-(-)-γ-amino-α-hydroxybutyryl side chain at the C-1
Matched Products: … MIKASIN 100 MG/2 ML IM/IV 1 AMPUL ... AMIKAVER 250 MG/2 ML AMPUL, 1 ADET ... AMIKETEM 250 MG/2 ML AMPUL, 1 ADET …
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergic receptors, since it is a sympathomimetric drug. Penbutolol also demonstrates high binding affinity to the...
Approved
Investigational
Matched Synonyms: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Iupac: … (2S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)propan-2-ol …
Matched Description: … Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker …
Displaying drugs 76 - 100 of 11935 in total