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Displaying drugs 76 - 100 of 8057 in total

Tetrachlorodecaoxide

WF10 is a chlorite-based, immunomodulating drug is developed by Nuvo Research Inc. Certain preclinical evidence and clinical pilot data suggest that WF10 may be effective in treating certain cancers. The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white blood cell) by modulating the...
Approved
Investigational
Matched Description: … in combination with Xeloda (capecitabine) in the treatment of pancreatic cancer. ... The Corporation believes the research to-date demonstrates that WF10 acts on macrophages (a type of white ... The Corporation has commenced a Phase II clinical trial in an effort to demonstrate the efficacy of WF10 …

Lutetium Lu-177 vipivotide tetraxetan

Lutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. It consists of a radionuclide, lutetium Lu-177, linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment...
Approved
Matched Description: … It consists of a radionuclide, [lutetium Lu-177], linked to a moiety that binds to PSMA, a transmembrane ... recommended lutetium Lu-177 vipivotide tetraxetan be granted marketing authorization for the treatment of …
Matched Categories: … Diagnostic Uses of Chemicals …

Protionamide

Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Approved
Investigational
Matched Description: … Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections. …
Matched Categories: … Drugs for Treatment of Tuberculosis …

Etidronic acid

Etidronic acid is a first generation bisphosphonate similar to clodronic acid and tiludronic acid. These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate zoledronic acid, ibandronic acid,...
Approved
Matched Description: … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... [A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Neomycin

Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of Streptomyces fradiae. Neomycin is a complex comprised of three components, neomycin A, B, and C. Neomycin B, also known as framycetin, is the most active component of the complex and neomycin C is the isomer...
Approved
Vet approved
Matched Description: … C is the isomer of neomycin B, making these two stereoisomers the active components of neomycin. ... [L11979] Neomycin is a complex comprised of three components, neomycin A, B, and C. ... Neomycin is a broad-spectrum aminoglycoside antibiotic drug that is derived from the metabolic products of …
Matched Mixtures name: … SONDEX-OF ... Cortisporin-TC ... Cortisporin TC …

Dexmethylphenidate

Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002 . It is a norepinephrine-dopamine reuptake inhibitor (NDRI) and thus a psychostimulant . It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. The d-isomer is thought to have greater effect with fewer side effects than the l-isomer or...
Approved
Investigational
Matched Description: … Dexmethylphenidate is the dextrorotary form of methylphenidate introduced in 2002[A177181]. ... It is used for treatment of Attention Deficit Hyperactivity Disorder (ADHD)[Label,A177181]. …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Minocycline

Minocycline was first described in the literacture in 1966. It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive bacteria. Like other semisynthetic tetracyclines, minocycline has modifications to carbons 7-9 on the D ring to generate higher efficacy than previous tetracyclines. Minocycline was granted FDA approval...
Approved
Investigational
Matched Categories: … combinations of tetracyclines ... Antiinfectives for Treatment of Acne …

Metacycline

A broad-spectrum semisynthetic antibiotic related to tetracycline but excreted more slowly and maintaining effective blood levels for a more extended period.
Approved
Investigational
Matched Categories: … combinations of tetracyclines …

Sodium chloride

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed...
Approved
Vet approved
Matched Description: … It is listed on the World Health Organization Model List of Essential Medicines. ... table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of ... Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular …
Matched Mixtures name: … SOLUTION OF DEXTROSE 5 % IN NORMAL SALINE 0.9 % ... SOLUTION OF DEXTROSE 10 % IN NORMAL SALINE 0.9 % …
Matched Products: … Of Nacl .9% ... Certified Nas Phys.soln Of Nacl .9% W/V B.P. …

Butabarbital

Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other barbiturates.[A201977,L13613] This makes butabarbital a useful drug for treating severe insomnia and pre-operative anxiety.[A201977,L13613] Butabarbital is less commonly used in recent years, as more patients are typically prescribed benzodiazepines. Its short duration of action...
Approved
Illicit
Matched Description: … Butabarbital, or Butisol, is a fast onset barbiturate with short duration of action compared to other ... [A19735] Its short duration of action gives butabarbital a high abuse potential, comparable to [secobarbital …
Matched Categories: … combinations of barbiturates …

Benzthiazide

Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat...
Approved
Matched Description: … Thiazides also cause loss of potassium and an increase in serum uric acid. …
Matched Categories: … combinations of sulfonamides …

Piretanide

Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of other aromatically bonded functional groups.
Approved
Matched Description: … using a then-new method for introducing cyclic amine residues in an aromatic nucleus in the presence of …
Matched Categories: … combinations of sulfonamides …

Eptotermin alfa

A bone morphogenetic protein that is widely expressed during EMBRYONIC DEVELOPMENT. It is both a potent osteogenic factor and a specific regulator of nephrogenesis. Eptotermin alfa is an ingredient in the EMA-withdrawn product Osigraft.
Approved
Investigational
Withdrawn
Matched Description: … It is both a potent osteogenic factor and a specific regulator of nephrogenesis. …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Dibotermin alfa

Dibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. It is implanted in patients undergoing bone surgeries or those with fractures. BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions on the...
Approved
Investigational
Matched Description: … Through enhancing osteogenesis at the site of implantation, dibotermin alfa accelerates the healing of ... In a prospective clinical study of patients with an open tibial fracture, administration of dibotermin ... BMPs are subfamily of the transforming growth factor-β (TGF-β) superfamily that have different actions …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … [L10695] In a press release for the Randomized Evaluation of COVID-19 Therapy (RECOVERY) trial on 16 …
Matched Mixtures name: … SONDEX-OF …
Matched Categories: … Inducers of Drug Clearance ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Iophendylate

Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Description: … A number of clinicians have published on the dangers of oil myelography. ... In 1942 Van Wagenen (a neurosurgical colleague of Warrens, at the University of Rochester) identified ... Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization …
Matched Categories: … Diagnostic Uses of Chemicals …

Zinc dibutyldithiocarbamate

Zinc dibutyldithiocarbamate is a dermatological sensitizer and allergen. Sensitivity to zinc dibutyldithiocarbamate may be identified with a clinical patch test.
Approved
Experimental
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … As well as its antifungal activity, clotrimazole has become a drug of interest in treating several other ... widespread acceptance for the treatment of mycotic outbreaks such as vaginal yeast infections as well ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Categories: … combinations of imidazole derivatives …
Matched Products: … Fortinia OF …

Gadopiclenol

Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Description: … [L43817] In 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis ... [A254002,A254017] In September 2022, the use of gadopiclenol was approved by the FDA. ... (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues …
Matched Categories: … Diagnostic Uses of Chemicals …

Zinc acetate

Approved
Investigational
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Acitretin

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Description: … It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared ... An oral retinoid effective in the treatment of psoriasis. …
Matched Categories: … Retinoids for Treatment of Psoriasis …

Viomycin

Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete Streptomyces puniceus.
Approved
Matched Categories: … Drugs for Treatment of Tuberculosis …

Ioflupane I-123

Ioflupane (I-123) is a radiopharmaceutical used to image dopamine neurons and diagnose Parkinsonian syndromes.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Iopodic acid

Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by a weak organic acid that contains a tri-iodinated benzene ring with iodine at positions 2, 4 and 6. Due to its particular structure, it presents a high degree of lipid solubility and a...
Approved
Investigational
Withdrawn
Matched Description: … Iopodic acid, also known by the name of ipodate, is classified as a cholecystographic agent formed by ... [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque …
Matched Categories: … Diagnostic Uses of Chemicals …

Iotrolan

Nonionic, isotonic contrast medium designed for intrathecal use.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Displaying drugs 76 - 100 of 8057 in total