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Displaying drugs 76 - 100 of 13144 in total

Hemoglobin

The respiratory protein of the red blood cells. It consists primarily of globin and heme.
Approved
Experimental
Investigational

Luspatercept

Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.[A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients...
Approved
Investigational
Matched Description: … [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand ... name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood ... [L42455] Luspatercept is novel in that it ameliorates anemia via action on late-stage erythropoiesis, …

Turpentine

Turpentine, also known as spirit of turpentine, oil of turpentine, and wood turpentine, is a liquid extracted from live trees, mainly pine, through distillation of resin. It is used as a solvent and base material in organic synthesis reactions. Turpentine is composed of terpenes, mainly the monoterpenes alpha-pinene and beta-pinene...
Approved
Experimental
Matched Description: … It is used as a solvent and base material in organic synthesis reactions. …
Matched Mixtures name: … AXE BRAND HEAT OIL …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Choline magnesium trisalicylate

Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Trisalicylate significantly reduces methotrexate renal clearance, displacing methotrexate from protein, increasing the fraction unbound by 28% [A19653, A19654].
Approved

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Description: … and peripheral vasodilation in acute decongested heart failure. ... Heart failure is underpinned by numerous physiological changes, including alteration in β-adrenergic ... inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in …
Matched Mixtures name: … Milrinone Lactate in Dextrose …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
Matched Products: … Milrinone Lactate in Dextrose …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Cimetidine in Sodium Chloride ... DYNAMET TABLET 200MG (F/C) …

Acetylcysteine

Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Mixtures name: … AMINOPLASMAL 15% IN 500ML GLASS BOTTLE ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,20 SAŞE ... ASIST C 600 MG-300 MG TOZ IÇEREN SAŞE,30 SAŞE …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Sodium phosphate, monobasic

Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine. It usually results in a bowel movement after 30 minutes to 6 hours.
Approved
Matched Description: … It usually results in a bowel movement after 30 minutes to 6 hours. ... Sodium phosphate is a saline laxative that is thought to work by increasing fluid in the small intestine …
Matched Mixtures name: … Utira-C ... UR N-C Urinary Antiseptic ... NUTRIFLEX PLUS IN 1000ML TWIN FLEX …

Conestat alfa

C1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. The primary function of endogenous C1INH is to regulate the activation of the complement and contact system pathways. It does this through inhibition of several target proteases within...
Approved
Investigational
Matched Description: … Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system. ... Intravenous replacement of C1 esterase inhibitor results in reversal of acute symptoms of HAE. ... Down-stream effects of the lack of enzyme inhibition by C1 esterase inhibitor results in swelling due …
Matched Categories: … Drugs Used in Hereditary Angioedema …

Methenamine

Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane. In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate which is the hippuric acid salt of methenamine).
Approved
Vet approved
Matched Description: … In salt form it is used for the treatment of urinary tract infection (Example: methenamine hippurate …
Matched Mixtures name: … All-In-One UTI Emergency Kit ... Utira-C ... Utira-C …
Matched Categories: … Bridged-Ring Compounds …

Selenious acid

Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans ... studies to validate the results in larger populations [L1918]. ... It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant …
Matched Mixtures name: … Tracel Injektionslösung in einer Fertigspritze ... C. Vit-min Formula ... Vitamins C Plus E W.beta Carotene and Se …

Ledipasvir

Ledipasvir is a direct acting antiviral (DAA) medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most...
Approved
Matched Description: … In a joint recommendation published in 2016, the American Association for the Study of Liver Diseases ... Its use has also proven successful in the treatment of HCV in patients co-infected with HIV [A19627]. ... an infectious liver disease caused by infection with Hepatitis C Virus (HCV). …
Matched Categories: … Treatments for Hepatitis C ... Heterocyclic Compounds, 2-Ring ... Hepatitis C Virus NS5A Inhibitor ... Heterocyclic Compounds, Fused-Ring …

Fenofibric acid

Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia, and mixed dyslipidemia. It works to decrease elevated low-density lipoprotein cholesterol, total cholesterol, triglycerides, apolipoprotein B, while increasing high-density lipoprotein cholesterol.[A32038,L12855] Due to its high hydrophilicity and poor absorption profile, prodrug ,fenofibrate, and other conjugated compounds...
Approved
Matched Description: … Fenofibric acid is a lipid-lowering agent that is used in severe hypertriglyceridemia, primary hyperlipidemia …

Plecanatide

Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Iupac: … }-22-(2-carboxyethyl)-3,6,9,12,15,18,21,24,30,33,36-undecahydroxy-10-[(C-hydroxycarbonimidoyl)methyl] ... (4S)-4-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene ... ]amino}-4-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-38-{[(1S)-1-carboxy-3-methylbutyl]-C-hydroxycarbonimidoyl ... 2,5,8,11,14,17,20,23,31,34,37-undecaazabicyclo[14.13.13]dotetraconta-2,5,8,11,14,17,20,23,30,33,36-undecaen-25-yl]-C-hydroxycarbonimidoyl …
Matched Description: … It should not be used in children less than six years of age, and should be avoided in patients six years ... Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation …
Matched Categories: … Guanylate Cyclase-C Agonist ... Guanylyl Cyclase C Agonists …

Pyrantel

Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis . Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use...
Approved
Vet approved
Matched Description: … In humans, it is administered as pyrantel pamoate [A32282],[A32283],[L1893],[L1898]. ... Pyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% ... Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PAMOATO DE PIRENTEL SUSPENSION C 250 MG/ 5 ML …

Tannic acid

Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine....
Approved
Matched Description: … In the old days it was used as antidote against different poisons. ... Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Formoterol

Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … first approved for use in the United States in 2001. ... [L11256] It is available as a single-entity product [L10986,L11223] and in several formulations in combination ... Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was …
Matched Products: … CYCLOCAPS FORMOTERO12UG+IN ... FORMATRIS 6UG NOV IN+2PX60 ... FORMATRIS 6UG NOV IN+3PX60 …

Ibandronate

Ibandronate, or BM 21.0955, is a third generation, nitrogen containing bisphosphonate similar to zoledronic acid, minodronic acid, and risedronic acid.[A203111,A203138] It is used to prevent and treat postmenopausal osteoporosis.[L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss in dogs. Ibandronate was granted FDA...
Approved
Investigational
Matched Description: … in dogs. ... [L13805,L13808] Ibandronate was first described in the literature in 1993 as a treatment for bone loss …
Matched Products: … BONVIVA 3MG/3ML ILO IN FER ... OSTIVEA 3mg/3ml Solution for IV Injection in Pre-filled Syringe ... Ibandronsäure ratiopharm 3 mg Injektionslösung in einer Fertigspritze …

Sofpironium

Sofpironium is a "soft" anticholinergic analog of glycopyrronium that has been modified with a readily hydrolyzable ester moiety. Soft drugs are designed to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug design, in which a molecule contains a metabolically sensitive moiety that promotes rapid metabolism to inactive...
Approved
Investigational
Matched Description: … to reduce systemic toxicity while enhancing local efficacy by employing retrometabolic drug design, in ... [L51103,L51108] It has also been available in Japan since 2020 under the brand name Ecclock.[L51103] ... [L51108,L51109] Sofpironium bromide (Sofdra) was approved by the FDA in June 2024 for the topical …

Oxygen

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow...
Approved
Vet approved
Matched Description: … increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in ... the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs …
Matched Mixtures name: … Oxygen In Helium Mix ... Nitrous Oxide In Oxygen ... Oxygen In Helium Mixture …
Matched Products: … Oxygen Size C …

Ensulizole

Ensulizole, also known as 2-phenylbenzimidazole-5-sulfonic acid, is a water-soluble sunscreen agent that absorbs strongly at UV-B wavelengths. It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter compounds due to its minimal protection against UV-A wavelengths. Due to its water solubility, ensulizole is commonly...
Approved
Matched Description: … It is commonly found in cosmetic products and sunscreen formulas in combination with other UV filter ... Due to its water solubility, ensulizole is commonly used in products formulated to feel light and less ... concentration of ensulizole is 148 mM although concentrations ranging between 74 and 148mM can be found in …
Matched Mixtures name: … Force C Premium SPF 15 ... Queens Rose Whole In One Sunblock ... Essential-C Day Moisture SPF 30 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …
Matched Products: … Covergirl Outlast All Day Stay Fabulous 3-IN-1 Foundation …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … the body, a deficiency in this molecule does not translate into disease conditions. ... These molecules have structural similarities to glucose and are involved in cellular signaling. ... molecule that does not qualify to be an essential vitamin because even though its presence is vital in …
Matched Mixtures name: … Lipo-B-C Tab ... Stress B&c Tab ... C. Vit-min Formula …

Lomitapide

Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).
Approved
Investigational
Matched Description: … Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, Fused-Ring …

Insulin beef

Insulin beef has been discontinued in the US and Canada since 2017.
Approved
Matched Description: … Insulin beef has been discontinued in the US and Canada since 2017.[L10827] …
Matched Categories: … Drugs Used in Diabetes …

Bempedoic acid

High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. Caused by genetic mutations or lifestyle factors, hypercholesterolemia can significantly reduce quality of life and increase the risk of mortality from cardiovascular disease. About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are...
Approved
Investigational
Matched Description: … [L12153] About 1 in 4 patients, or 15 million Americans with elevated LDL-C, are insufficiently managed ... High levels of LDL cholesterol (LDL-C) are a major risk factor for cardiovascular events. ... once a day for reducing LDL cholesterol levels in statin-refractory patients. …
Displaying drugs 76 - 100 of 13144 in total