Displaying drugs 1001 - 1025 of 1514 in total
2-Formyl-Protoporphryn Ix
Experimental
Matched Name: … 2-Formyl-Protoporphryn Ix …
Matched Iupac: … lambda4-iron(4+) (15Z,20R)-5,9-bis(2-carboxyethyl)-20-ethenyl-15-(hydroxymethylidene)-4,10,14,19-tetramethyl …
Matched Iupac: … lambda4-iron(4+) (15Z,20R)-5,9-bis(2-carboxyethyl)-20-ethenyl-15-(hydroxymethylidene)-4,10,14,19-tetramethyl …
Cefonicid
A second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
Approved
Investigational
Matched Description: … It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone …
Matched Salts name: … Cefonicid sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFONICID SODICO …
Matched Salts name: … Cefonicid sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … CEFONICID SODICO …
Dicloxacillin
One of the penicillins which is resistant to penicillinase.
Approved
Investigational
Vet approved
Matched Salts name: … Dicloxacillin sodium ... Dicloxacillin sodium anhydrous …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Dicloxacillin Sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … Dicloxacillin Sodium …
Cefaclor
Semisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Approved
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … FORIFEK FORTE ... PANORAL FORTE ... CEC FORTE TROCKENSAFT …
Matched Products: … FORIFEK FORTE ... PANORAL FORTE ... CEC FORTE TROCKENSAFT …
(6R)-Folinic acid
Experimental
Matched Synonyms: … [6R]-5-formyl-5,6,7,8-tetrahydrofolate ... L-Glutamic acid, N-[4-[[[(6R)-2-amino-5-formyl-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino] ... N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl} …
Matched Iupac: … (2S)-2-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Categories: … Folic Acid and Derivatives …
Matched Iupac: … (2S)-2-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Categories: … Folic Acid and Derivatives …
Bevantolol
Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension. Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors, in addition to antagonist activity at beta-1 receptors.
Experimental
Matched Description: … the treatment of angina pectoris and hypertension. ... Mechanism of Action Animal experiments confirm both agonist and antagonist effects on alpha-receptors ... Bevantolol is a beta-1 adrenoceptor antagonist that has been shown to be as effective as other beta blockers for …
Matched Categories: … bevantolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … BETA FORM …
Matched Categories: … bevantolol and thiazides ... Beta Blocking Agents and Thiazides ... Beta Blocking Agents, Selective, and Thiazides …
Matched Products: … BETA FORM …
10-formyl-5,8,10-trideazafolic acid
Experimental
Matched Name: … 10-formyl-5,8,10-trideazafolic acid …
Succinylcholine
Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter acetylcholine (ACh) linked by their acetyl groups. It has been widely used for over 50 years, most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. Its...
Approved
Matched Description: … Its rapid onset and offset, with effects beginning within 60 seconds of intravenous administration and ... a means of neuromuscular blockade during intubation and surgical procedures. ... [A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as …
Matched Products: … LYSTHENON FORTE %2 ENJEKSİYONLUK ÇÖZELTİ, 25 AMPUL ... Pharmaniaga Suxamethonium Chloride 100mg/2ml Solution for Injection ... MARTINDALE PHARMA SUXAMETHONIUM CHLORIDE SOLUTION FOR INJECTION 50MG/ML …
Matched Products: … LYSTHENON FORTE %2 ENJEKSİYONLUK ÇÖZELTİ, 25 AMPUL ... Pharmaniaga Suxamethonium Chloride 100mg/2ml Solution for Injection ... MARTINDALE PHARMA SUXAMETHONIUM CHLORIDE SOLUTION FOR INJECTION 50MG/ML …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …
Minnelide
Investigational
Matched Synonyms: … -one, 3b,4,4a,6,6a,7a,7b,8b,9,10-decahydro-8b-methyl-6a-(1-methylethyl)-6-((phosphonooxy)methoxy)-, sodium …
Matched Iupac: … tetraoxaheptacyclo[11.7.0.0^{2,4}.0^{2,9}.0^{5,7}.0^{9,11}.0^{14,18}]icos-14(18)-en-8-yl]oxy}methyl phosphate …
Matched Iupac: … tetraoxaheptacyclo[11.7.0.0^{2,4}.0^{2,9}.0^{5,7}.0^{9,11}.0^{14,18}]icos-14(18)-en-8-yl]oxy}methyl phosphate …
Benzydamine
Benzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties. It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal system.
Although the indazole analogue benzydamine is a...
Approved
Matched Description: … It is used topically for pain relief and anti-inflammatory treatment of the mouth, throat, or muscoskeletal ... hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and ... benzydamine is a non-steroidal anti-inflammatory drug (NSAID), it has various physicochemical properties and …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …
Matched Mixtures name: … Anti-inflammatory Lozenge (with antibacterial) (Eucalyptus and Menthol) ... Difflam plus ANAESTHETIC Sore Throat Lozenges (Sugar Free) Menthol and Eucalyptus Flavour ... FARHEX FORTE SPREY …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Alimentary Tract and Metabolism ... Mouthwashes and Gargles ... Antiinflammatory and Antirheumatic Products ... Genito Urinary System and Sex Hormones …
Matched Products: … Tantum Verde forte - Mundspray ... BENZIRIN® FORTE 0.3% SOLUCIÓN BUCAL ... Difflam Forte Anti-Inflammatory Throat Spray …
RU82197
Experimental
Matched Synonyms: … 4-[2-Acetylamino-2-(1-biphenyl-4-ylmethyl-2-oxo-azepan-3-ylcarbamoyl)-ethyl]-2-formyl-benzoic acid …
Cisatracurium
Cisatracurium is a non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form, cisatracurium besylate.[A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly used neuromuscular blocking agents in intensive care.[A253592,A253597]. Cisatracurium acts on cholinergic receptors, blocking neuromuscular transmission. This action is...
Approved
Investigational
Matched Description: … [A243416,A253592] Cisatracurium has an intermediate duration of action and is one of the most commonly ... [A243416,A253592] Cisatracurium is an R-cis-R-cis isomer of [atracurium] and has approximately 3 times ... non-depolarising neuromuscular blocking agent of the benzylisoquinolinium class, available in its salt form …
Matched Products: … Nimbex Forte Injection 150 mg/30 ml ... Cisatracurium-hameln 2 mg/ml solution for injection/infusion ... Cisatracurium Kabi 2 mg/ml solution for injection or infusion …
Matched Products: … Nimbex Forte Injection 150 mg/30 ml ... Cisatracurium-hameln 2 mg/ml solution for injection/infusion ... Cisatracurium Kabi 2 mg/ml solution for injection or infusion …
AVR-RD-05
AVR-RD-05 is a gene therapy comprising genetically modified autologous stem cells transduced ex vivo with a lentiviral vector encoding the human iduronate-2-sulfatase (IDS) enzyme. It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII).
Investigational
Matched Synonyms: … Ex vivo, lentiviral vector (LV)-mediated, genetically modified autologous cell therapy intended for the …
Matched Description: … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII) …
Matched Description: … It is under investigation for the treatment of Hunter Syndrome (Mucopolysaccharidosis Type II, MPSII) …
Lipoic acid
A vitamin-like antioxidant.
Approved
Investigational
Nutraceutical
Matched Synonyms: … Thioctic acid D-form …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Matched Categories: … Alimentary Tract and Metabolism ... Enzymes and Coenzymes ... Various Alimentary Tract and Metabolism Products …
Glucosamine
Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional benefits to nonsteroidal anti-inflammatory drugs treating the painful symptoms of OA. Glucosamine is commonly used over the counter as...
Approved
Investigational
Matched Description: … changes, and synovial membrane inflammation. ... Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone ... as a medical therapy varies due to contradictory and findings with unclear clinical significance during …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... CARTICAP FOR …
Matched Salts name: … Glucosamine sulfate sodium chloride ... Glucosamine sulfate potassium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROSULF FORTE ... Donna Forte Capsule 500mg ... CUINE POWDER FOR ORAL SOLUTION …
Matched Mixtures name: … Bee Venom Joint And Bone Therapy Drops ... Blackmores Joint Formula with Glucosamine and Chondroitin ... CARTICAP FOR …
Matched Salts name: … Glucosamine sulfate sodium chloride ... Glucosamine sulfate potassium chloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … PROSULF FORTE ... Donna Forte Capsule 500mg ... CUINE POWDER FOR ORAL SOLUTION …
Sulbactam
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.
Approved
Matched Description: … Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus. ... with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for …
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium …
Matched Salts name: … Sulbactam sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … SULFACETAMIDA SODICA TOR 30% GOTAS OFTALMICAS …
Matched Mixtures name: … Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium ... Ampicillin Sodium and Sulbactam Sodium …
Matched Salts name: … Sulbactam sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … SULFACETAMIDA SODICA TOR 30% GOTAS OFTALMICAS …
Methylprednisolone
Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814]
Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Mixtures name: … Methylprednisolone Sodium Succinate for Injection, USP ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … METHYLPREDNISOLONE POWDER FOR SOLUTION FOR INJECTION 500mg ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …
Matched Products: … METHYLPREDNISOLONE POWDER FOR SOLUTION FOR INJECTION 500mg ... METILPREDNISOLONA SODIO SUCCINATO. METIL PREDNISOLONA 500 MG. PARA RECONSTITUIR A 4 ML. …
Archexin
Investigational
Matched Synonyms: … 5'-DG-DC-T-DG-DC-DA-T-DG-DA-T-DC-T-DC-DC-T-T-DG-DG-DC-DG-3', SODIUM PHOSPHOTHIOATE …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
ABSK-012
Investigational
Matched Synonyms: … 3-(5-cyano-4-(cyclopropylamino)pyridin-2-yl)-1-(6-formyl-5-((4-methyl-2-oxopiperazin-1-yl)methyl)pyridin ... N′-[5-Cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl]-2- ... Urea, N′-[5-cyano-4-(cyclopropylamino)-2-pyridinyl]-N-[6-formyl-5-[(4-methyl-2-oxo-1-piperazinyl)methyl …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …
Matched Iupac: … 3-[5-cyano-4-(cyclopropylamino)pyridin-2-yl]-1-{6-formyl-5-[(4-methyl-2-oxopiperazin-1-yl)methyl]pyridin …
Acetylcysteine
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168]
Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Description: … Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment ... [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium Acetylcysteine Mecobalamin Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Antidote for Acetaminophen Overdose …
Matched Products: … SIRAN FORTE ... ANCARE SOLUTION FOR IV INFUSION 100MG/ML ... HIDONAC SOLUTION FOR INFUSION 5 g/25 ml …
Matched Mixtures name: … Levomefolate Calcium Acetylcysteine and Mecobalamin Algal ... Levomefolate Calcium, Acetylcysteine, Mecobalamin and Algal ... Levomefolate Calcium Acetylcysteine Mecobalamin Algal …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Cough and Cold Preparations ... Antidote for Acetaminophen Overdose …
Matched Products: … SIRAN FORTE ... ANCARE SOLUTION FOR IV INFUSION 100MG/ML ... HIDONAC SOLUTION FOR INFUSION 5 g/25 ml …
Cefadroxil
Long-acting, broad-spectrum, water-soluble, cephalexin derivative.
Approved
Vet approved
Withdrawn
Matched Salts name: … Cefadroxil sodium …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VOCEFA FORTE ... CEFFORD FORTE ... OPICEF FORTE …
Matched Categories: … Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … VOCEFA FORTE ... CEFFORD FORTE ... OPICEF FORTE …
Formoterol
Formoterol is an inhaled beta2-agonist used in the management of COPD and asthma that was first approved for use in the United States in 2001. It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic mixture of its active (R;R)- and inactive (S;S)-enantiomers....
Approved
Investigational
Matched Description: … this reason, treatment guidelines for asthma recommend its use as both a reliever and maintenance medication ... first approved for use in the United States in 2001. ... [L10986] It acts on bronchial smooth muscle to dilate and relax airways, and is administered as a racemic …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases ... formoterol and mometasone ... formoterol and budesonide ... formoterol and fluticasone …
Matched Products: … FORMO-ARISTO 12UG ... Foradil Dry Powder Capsules for Inhalation ... FORADIL CAPSULE FOR INHALATION 12 mcg/capsule …
Matched Mixtures name: … Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate ... Budesonide and Formoterol Fumarate Dihydrate …
Matched Categories: … Adrenergics for Systemic Use ... Drugs for Obstructive Airway Diseases ... formoterol and mometasone ... formoterol and budesonide ... formoterol and fluticasone …
Matched Products: … FORMO-ARISTO 12UG ... Foradil Dry Powder Capsules for Inhalation ... FORADIL CAPSULE FOR INHALATION 12 mcg/capsule …
Trastuzumab
Produced in CHO cell cultures, trastuzumab is a recombinant IgG1 kappa, humanized monoclonal antibody that selectively binds with high affinity in a cell-based assay (Kd = 5 nM) to the extracellular domain of the human epidermal growth factor receptor protein (HER2). It is used as a treatment of human epidermal...
Approved
Investigational
Matched Description: … Trastuzumab binds to HER2 and suppresses cancer cell growth, proliferation, and survival directly and ... that the overexpression or gene amplification of HER2 has been found in about 20–30% of breast cancers and ... cancer, it is the second biosimilar approved in the U.S. for the treatment of cancer. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … HERZUMA® 440MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion ... HERZUMA® 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …
Matched Categories: … Amino Acids, Peptides, and Proteins ... pertuzumab and trastuzumab ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … HERZUMA® 440MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION ... Herzuma (trastuzumab) 150 mg Powder for Concentrate for Solution for Infusion ... HERZUMA® 150MG POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION …
Gentamicin
Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.[A234339,A234354] Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly useful for the treatment...
Approved
Vet approved
Matched Description: … can also contribute to dose optimization and reduced adverse effects. ... Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea ... is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... Gentamicin Sulfate In 0.9% Sodium Chloride Injection …
Matched Categories: … Ophthalmological and Otological Preparations ... Medications that reduce magnesium levels ... Antibiotics for Topical Use ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BIOGEN FORTE ... Gentamicin Sulfate In Sodium Chloride ... Gentamicin Sulfate in Sodium Chloride …
Matched Mixtures name: … Garasone Ophthalmic and Otic Solution ... Gentamicin Sulfate In 0.9% Sodium Chloride Injection …
Matched Categories: … Ophthalmological and Otological Preparations ... Medications that reduce magnesium levels ... Antibiotics for Topical Use ... Antibacterials for Systemic Use ... Antiinfectives for Systemic Use …
Matched Products: … BIOGEN FORTE ... Gentamicin Sulfate In Sodium Chloride ... Gentamicin Sulfate in Sodium Chloride …
Displaying drugs 1001 - 1025 of 1514 in total