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Displaying drugs 101 - 125 of 176 in total

Hydrocortisone phosphate

Approved
Vet approved
Matched Salts name: … Hydrocortisone sodium phosphate …
Matched Categories: … Hydrocortisone and derivatives ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Sugammadex

Sugammadex is a selective relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and vecuronium bromide during surgery. Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary paralysis and are especially useful for general anesthesia, ventilation, or tracheal intubation that patients may require...
Approved
Matched Description: … Sugammadex (brand name Bridion) is marketed by Merck Sharp and Dohme, and was approved by the United ... relaxant binding agent indicated for reversal of neuromuscular blockade induced by rocuronium bromide and ... Rocuronium bromide and vecuronium bromide are neuromuscular blocking medications that cause temporary …
Matched Salts name: … Sugammadex sodium …

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Description: … [A260271] It gained EMA and Health Canada approval on November 26, 2012 [L47216] and December 3, 2013 ... Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C ... [A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Rifamycin

Rifamycin is the prime member of the rifamycin family which are represented by drugs that are a product of fermentation from the gram-positive bacterium Amycolatopsis mediterranei, also known as Streptomyces mediterranei. The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence...
Approved
Investigational
Matched Description: … Falk Pharma Gmbh and it was granted a waiver for the tested conditions.[L4801] ... Some small modifications where performed in this inactive compound and with the creation of rifamycin ... ] Rifamycin has had several direct derivative products such as rifamycin SV, rifaximin, rifampin and …
Matched Salts name: … Rifamycin sodium …
Matched Categories: … Alimentary Tract and Metabolism …

Semaglutide

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Description: … The use of salt forms of semaglutide, including semaglutide sodium and semaglutide acetate, has not been ... and reducing blood glucose. ... [A31421,L8681] Other members of this drug class include [Exenatide] and [Liraglutide]. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Pitavastatin

Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Description: … lipid levels and ultimately reduce the risk of cardiovascular disease. ... studies to significantly reduce the risk of development of CVD and all-cause mortality. ... inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and …
Matched Salts name: … Pitavastatin sodium …

Octisalate

Also known as Ethylhexyl Salicylate. Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other...
Approved
Investigational
Matched Description: … It is an ester of salicylic acid and 2-ethylhexanol. ... Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters. …
Matched Mixtures name: … Sodium Sulfacetamide and Sulfur ... SPF 30 Alcohol-free Spray Sunscreen ... SPF 30 Alcohol-free Spray-ON Sunscreen …

Sodium ascorbate

Approved
Nutraceutical
Matched Synonyms: … Sodium ascorbate ... Vitamin C sodium ... sodium L-ascorbate …
Matched Name: … Sodium ascorbate …
Matched Iupac: … sodium (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate …
Matched Mixtures name: … Peg-3350, Sodium Sulfate, Sodium Chloride, Potassium Chloride, Sodium Ascorbate and Ascorbic Acid ... PEG-3350, Electrolytes, and Ascorbate ... Bugs Bunny and Friends Multiple Vitamins …
Matched Categories: … Vitamin C and analogues ... Diet, Food, and Nutrition …
Matched Products: … Mega-C-sodium Inj 250mg/ml ... Sodium Ascor Crystal 888.8mg/gm USP …

Betamethasone

Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.
Approved
Vet approved
Matched Synonyms: … beta-Methasone alcohol …
Matched Description: … Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. ... [A192444] Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity. ... [A192444] It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally …
Matched Mixtures name: … Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate ... Betamethasone Sodium Phosphate and Betamethasone Acetate …
Matched Salts name: … Betamethasone sodium phosphate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... betamethasone and mydriatics ... betamethasone and antiseptics ... betamethasone and antibiotics …
Matched Products: … Betnesol Eye and Ear Drops ... Betnesol Eye and Ear Drops 0.1% …

Warfarin

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Description: … , and drug interactions have also been documented with warfarin use. ... during pregnancy which can result in fetal bleeding, spontaneous abortion, preterm birth, stillbirth, and ... Additional adverse effects such as necrosis, purple toe syndrome, osteoporosis, valve and artery calcification …
Matched Salts name: … Warfarin sodium …
Matched Categories: … Warfarin and isomers ... Blood and Blood Forming Organs …
Matched Products: … Warfarin Sodium ... WARFARIN SODIUM CLATHRATE …

Dexamethasone

Dexamethasone, or MK-125, is a corticosteroid fluorinated at position 9 used to treat endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and other conditions. Developed in 1957, it is structurally similar to other corticosteroids like hydrocortisone and prednisolone. Dexamethasone was granted FDA approval on 30 October 1958....
Approved
Investigational
Vet approved
Matched Description: … dermatologic, allergic, ophthalmic, gastrointestinal, respiratory, hematologic, neoplastic, edematous, and ... L10701] Developed in 1957, it is structurally similar to other corticosteroids like [hydrocortisone] and ... Dexamethasone reduced deaths by approximately one third in patients requiring ventilation and by one …
Matched Mixtures name: … Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% ... Dexamethasone Sodium Phosphate 0.1% / Finasteride 0.1% / Minoxidil 5% / Tretinoin 0.025% ... Neomycin and Polymyxin B Sulfates and Dexamethasone …
Matched Salts name: … Dexamethasone sodium phosphate …
Matched Categories: … Alimentary Tract and Metabolism ... Sex Hormones and Insulins ... dexamethasone and antibiotics ... dexamethasone and antiinfectives ... dexamethasone and antiinfectives …
Matched Products: … DEXAMETHASONE Sodium Phosphate ... Dexamethasone Sodium Phosphate ... Dexamethasone Sodium Phosphates …

Lactic acid

A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. It is produced by fermentation of a sugar source, such as...
Approved
Vet approved
Matched Description: … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste ... It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the …
Matched Mixtures name: … COMPOUND SODIUM LACTATE INTRAVENOUS INFUSION BP ... COMPOUND SODIUM LACTATE INTRAVENOUS INFUSION BP ... COMPOUND SODIUM LACTATE INTRAVENOUS INFUSION BP …
Matched Salts name: … Sodium lactate …
Matched Categories: … Basic Ointments and Protectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Products: … Sodium Lactate …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Salts name: … Fucidate sodium …
Matched Products: … Axcel Sodium Fusidate 250 Tablet ... VAXCEL SODIUM FUSIDATE-500MG INJECTION ... Fusigen Ointment (Sodium Fusidate BP 2 % w/w) …

Montelukast

Montelukast was first approved for clinical use by the US FDA in 1998 as Merck's brand name Singulair. The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.[L6301,L6304,L6307,L6310,L6325,L6328,L6331] Although capable of demonstrating effectiveness, the use of such LTRAs like montelukast is typically in addition to or...
Approved
Matched Description: … has since become available as a generic and as a brand name product. ... montelukast to elicit neuropsychiatric effects like agitation, hallucinations, suicidal behaviour, and ... L6325,L6328,L6331] the drug still sees extensive use worldwide via millions of prescriptions annually and …
Matched Salts name: … Montelukast sodium …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Montelukast Sodium ... Montelukast sodium ... MONTELUKAST SODIUM …

Methylprednisolone

Methylprednisolone is a prednisolone derivative glucocorticoid with higher potency than prednisone. It was first described in the literature in the late 1950s.[A188811,A188814] Methylprednisolone was granted FDA approval on 24 October 1957. In the outbreak of COVID-19, low dose methylprednisolone-based therapy was successful in treating COVID-19-associated pneumonia in one patient with...
Approved
Vet approved
Matched Mixtures name: … Methylprednisolone Sodium Succinate for Injection, USP ... Methylprednisolone Sodium Succinate for Injection, USP …
Matched Categories: … Sex Hormones and Insulins ... methylprednisolone and antibiotics ... methylprednisolone and antiinfectives ... methylprednisolone and antiinfectives ... Ophthalmological and Otological Preparations …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Salts name: … Meropenem sodium …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Aliskiren

Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension. It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. Aliskiren has been proven to efficacious in reducing blood pressure when used alone or in...
Approved
Investigational
Matched Description: … [A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. ... Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension …
Matched Categories: … valsartan and aliskiren ... aliskiren and amlodipine ... aliskiren and hydrochlorothiazide ... aliskiren, amlodipine and hydrochlorothiazide …

Dextrose, unspecified form

Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Vet approved
Matched Description: … through aerobic or anaerobic respiration and fermentation. ... Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and ... L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. …
Matched Mixtures name: … Alcohol 5% and Dextrose 5% Inj USP ... Alcohol 5% and Dextrose 5% Injection USP ... Dextrose and Sodium Chloride …

Ajmaline

An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Description: … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a ... It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac ... many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and …
Matched Categories: … Ajmaline and derivatives ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Carbamazepine

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … and to treat pain resulting from trigeminal neuralgia. ... Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures …
Matched Categories: … Sodium Channel Blockers …

Ranolazine

Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant disability while interfering with daily activities. Ranolazine is a well-tolerated piperazine derivative used for the management of this condition, offering relief from uncomfortable and debilitating symptoms. With a mechanism of action different from drugs used to treat...
Approved
Investigational
Matched Description: … Chronic angina is a common cardiovascular condition affecting millions worldwide and causes significant ... piperazine derivative used for the management of this condition, offering relief from uncomfortable and …
Matched Categories: … Sodium Channel Blockers …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor ... by inhibiting glucose reabsorption in the proximal tubule of the nephron and causing glycosuria. ... [A261596] When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control …
Matched Mixtures name: … Dapagliflozin and Metformin Hydrochloride ... Dapagliflozin and Metformin Hydrochloride …
Matched Categories: … Sodium-Glucose Transporter 2 Inhibitors ... Sodium-glucose Cotransporter 2 (SGLT2) Inhibitors ... Sodium-Glucose Transport Proteins, antagonists & inhibitors ... Alimentary Tract and Metabolism ... metformin and dapagliflozin …

Rifampin

Rifampin, also known as rifampicin, is a broad-spectrum antimicrobial that was first discovered in 1965 and clinically used in 1968. Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).
Approved
Matched Description: … rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and ... [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent …
Matched Salts name: … Rifampicin sodium …
Matched Categories: … dapsone and rifampicin ... rifampicin and isoniazid ... dapsone, rifampicin and clofazimine ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide and isoniazid …

Colistimethate

Colistimethate is an antibiotic that has been shown to have bactericidal activity against aerobic gram-negative microorganisms. Colistimethate is particularly indicated when the infection is caused by sensitive strains of Pseudomonas aeruginosa.
Approved
Vet approved
Matched Salts name: … Colistimethate sodium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … Colistimethate Sodium …

Mannitol

Mannitol is an osmotic diuretic that is metabolically inert in humans and occurs naturally, as a sugar or sugar alcohol, in fruits and vegetables. Mannitol elevates blood plasma osmolality, resulting in enhanced flow of water from tissues, including the brain and cerebrospinal fluid, into interstitial fluid and plasma. As a...
Approved
Investigational
Matched Description: … or sugar alcohol, in fruits and vegetables. ... As a result, cerebral edema, elevated intracranial pressure, and cerebrospinal fluid volume and pressure ... cerebrospinal fluid, into interstitial fluid and plasma. …
Matched Mixtures name: … Additive Solution Sodium Adenine Glucose Mannitol (sagm) ... INFUSOL M20S (Mannitol 17.5%w/v and Sorbitol 2.5%w/v Intravenous Infusion) ... TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND …
Matched Categories: … Diet, Food, and Nutrition ... Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Cough and Cold Preparations ... Blood Substitutes and Perfusion Solutions …
Displaying drugs 101 - 125 of 176 in total