Displaying drugs 101 - 125 of 241 in total
Omeprazole
Originally approved by the FDA in 1989, omeprazole is a proton-pump inhibitor, used to treat gastric acid-related disorders. These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases characterized by the oversecretion of gastric acid. This drug was the first clinical useful drug in its class,...
Approved
Investigational
Vet approved
Matched Iupac: … 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Matched Description: … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults ... These disorders may include gastroesophageal reflux disease (GERD), peptic ulcer disease, and other diseases ... This drug was the first clinical useful drug in its class, and its approval was followed by the formulation …
Matched Mixtures name: … Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate ... Omeprazole and Sodium Bicarbonate …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring ... Alimentary Tract and Metabolism ... Omeprazole and enantiomer …
Matched Products: … Up and Up Omeprazole ... Berkley and Jensen Omeprazole ... Foster and Thrive Omeprazole …
Dulaglutide
Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct therapy to diet and exercise in the management of 2 diabetes (T2DM). Dulaglutide was initially approved by the FDA in 2014, and...
Approved
Investigational
Matched Description: … therapy to diet and exercise in the management of 2 diabetes (T2DM). ... (GLP-1) receptor agonist designed using recombinant DNA technology; it has been approved as an adjunct ... Dulaglutide, marketed by Eli Lilly as Trulicity, is a once-weekly subcutaneous glucagon-like peptide-1 …
Matched Categories: … Glucagon-like peptide-1 (GLP-1) analogues ... GLP-1 Agonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRULİCİTY 0.75 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TRULİCİTY 1.5 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Matched Categories: … Glucagon-like peptide-1 (GLP-1) analogues ... GLP-1 Agonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRULİCİTY 0.75 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TRULİCİTY 1.5 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET …
Hydrogen peroxide
Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition....
Approved
Vet approved
Matched Description: … whites, and dried egg yolks. ... cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg ... and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369 …
Matched Mixtures name: … Prevention Wound and Burn ... QCare Oral Cleansing and Suctioning System, Q4 ... Oral Cleansing and Suctioning System, q2 …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Salon Safety Furniture and Surface 1 Minute Sanitizer ... Up and Up 3 Hydrogen Peroxide Wipes ... Multi Purpose Sanitizer and Cleaner Wipes …
Matched Mixtures name: … Prevention Wound and Burn ... QCare Oral Cleansing and Suctioning System, Q4 ... Oral Cleansing and Suctioning System, q2 …
Matched Categories: … Alimentary Tract and Metabolism ... Antiseptics and Disinfectants ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Products: … Salon Safety Furniture and Surface 1 Minute Sanitizer ... Up and Up 3 Hydrogen Peroxide Wipes ... Multi Purpose Sanitizer and Cleaner Wipes …
Brincidofovir
Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. It is a lipid conjugate pro-drug of the acyclic nucleotide analogue cidofovir[L34404,A235725] - this lipid conjugate improves drug delivery to the target cells and significantly reduces the nephrotoxicity typically associated with cidofovir therapy.[A235725,A235735] Due to its...
Approved
Investigational
Matched Iupac: … ({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)[3-(hexadecyloxy) …
Matched Description: … Cidofovir itself has broad antiviral activity against several DNA viruses,[A235725] resulting in brincidofovir ... Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. ... (AdV), and Epstein-Barr virus (EBV), amongst others. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Matched Description: … Cidofovir itself has broad antiviral activity against several DNA viruses,[A235725] resulting in brincidofovir ... Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections. ... (AdV), and Epstein-Barr virus (EBV), amongst others. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytomegalovirus Nucleoside Analog DNA Polymerase Inhibitor ... Nucleosides and Nucleotides Excl. Reverse Transcriptase Inhibitors …
Teplizumab
Teplizumab (teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 diabetes (T1D).[A241480,A241045,A241475,L44091] T1D is an autoimmune condition in which T cell-mediated destruction of pancreatic β cells leads to loss of insulin production, impaired glycemic control, and reliance on exogenous insulin. Anti-CD3 therapy...
Approved
Investigational
Matched Description: … teplizumab-mzwv) is a humanized IgG1 kappa CD3-directed monoclonal antibody used to delay the onset of type 1 ... November 2022, teplizumab was approved by the FDA as the first drug that can delay the onset of type 1 ... L44091] Fc-receptors can bind to the "tail-end" anti-CD3 antibodies in an antigen-non-specific manner and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Oxaliplatin
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Iupac: … (3aR,7aR)-octahydro-2',5'-dioxaspiro[cyclohexa[d]1,3-diaza-2-platinacyclopentane-2,1'-cyclopentane]-3 …
Matched Description: … damage through DNA crosslinking, particularly intrastrand and interstrand crosslinking. ... A260396] Like most platinum-based compounds, oxaliplatin's mechanism of action is primarily through DNA ... However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXERIN 2 MG/ML ... OXITAN INJECTION 2 MG/ML ... ICEREN FLAKON, 1 ADET …
Matched Description: … damage through DNA crosslinking, particularly intrastrand and interstrand crosslinking. ... A260396] Like most platinum-based compounds, oxaliplatin's mechanism of action is primarily through DNA ... However, due to the structure of oxaliplatin, its adducts make the binding of mismatch repair protein to DNA …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … OXERIN 2 MG/ML ... OXITAN INJECTION 2 MG/ML ... ICEREN FLAKON, 1 ADET …
Levomefolic acid
Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma ... membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA ... synthesis, cysteine cycle and regulation of homocysteine, where it methylates homocysteine and forms …
Matched Salts cas: … 1429498-11-2 ... 151533-22-1 ... 1181972-37-1 …
Matched Mixtures name: … PNV Tabs 20-1 ... Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Description: … of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma ... membranes including the blood-brain barrier into various tissues where it plays an essential role in the DNA ... synthesis, cysteine cycle and regulation of homocysteine, where it methylates homocysteine and forms …
Matched Salts cas: … 1429498-11-2 ... 151533-22-1 ... 1181972-37-1 …
Matched Mixtures name: … PNV Tabs 20-1 ... Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Drospirenone, Ethinyl Estradiol and Levomefolate Calcium and Levomefolate Calcium …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Enzymes and Coenzymes ... Folic Acid and Derivatives ... Amino Acids, Peptides, and Proteins …
Somatotropin
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Synonyms: … Somatropin (recombinant DNA origin) ... Somatropin(recombinant DNA origin) ... Human growth hormone …
Matched Description: … Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and ... It has an identical primary protein structure to endogenous human growth hormone. ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults …
Matched Categories: … Recombinant Human Growth Hormone ... Human Growth Hormone, antagonists & inhibitors ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Matched Products: … GROWTROPINAQ 16 U /2 ML INYECTABLE ... ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg …
Matched Description: … Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and ... It has an identical primary protein structure to endogenous human growth hormone. ... fat mass regulation, blood glucose level regulation, and lipid regulation in both children and adults …
Matched Categories: … Recombinant Human Growth Hormone ... Human Growth Hormone, antagonists & inhibitors ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …
Matched Products: … GROWTROPINAQ 16 U /2 ML INYECTABLE ... ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg …
Etoposide
A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division,...
Approved
Matched Iupac: … (10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death …
Matched Salts cas: … 117091-64-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICEREN FLAKON, 1 ADET ... LASTET 100 MG ENJEKTABL, 1 ADET ... INFUZYON COZELTISI ICEREN FLAKON, 1 ADET …
Matched Description: … Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. ... This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. ... Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death …
Matched Salts cas: … 117091-64-2 …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … ICEREN FLAKON, 1 ADET ... LASTET 100 MG ENJEKTABL, 1 ADET ... INFUZYON COZELTISI ICEREN FLAKON, 1 ADET …
Lenacapavir
HIV/AIDS remains an area of concern despite the introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and patient difficulty in adhering to treatment regimens.[A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 inhibition as a monotherapy in vitro, little to no cross-resistance...
Approved
Investigational
Matched Iupac: … -3-methylbut-1-yn-1-yl)pyridin-2-yl}-2-(3,5-difluorophenyl)ethyl]-2-[(2S,4R)-5,5-difluoro-9-(trifluoromethyl ... N-[(1S)-1-{3-[4-chloro-3-methanesulfonamido-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl]-6-(3-methanesulfonyl ... )-7,8-diazatricyclo[4.3.0.0^{2,4}]nona-1(6),8-dien-7-yl]acetamide …
Matched Description: … [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 ... introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and ... inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral agents, and …
Matched Categories: … Human Immunodeficiency Virus 1 Capsid Inhibitor ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring …
Matched Description: … [A244170, A244175] Lenacapavir is a first-in-class capsid inhibitor that demonstrates picomolar HIV-1 ... introduction of numerous successful therapies, mainly due to the emergence of multidrug resistance and ... inhibition as a monotherapy _in vitro_, little to no cross-resistance with existing antiretroviral agents, and …
Matched Categories: … Human Immunodeficiency Virus 1 Capsid Inhibitor ... Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring …
alpha-Tocopherol acetate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1- ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and …
Matched Mixtures name: … PNV Tabs 20-1 ... Vitamin & Mineral Formula 1 Dietary Supplement ... Vitamin and Mineral Drink Mix …
Matched Categories: … Diet, Food, and Nutrition ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 50 ADET …
Matched Mixtures name: … PNV Tabs 20-1 ... Vitamin & Mineral Formula 1 Dietary Supplement ... Vitamin and Mineral Drink Mix …
Matched Categories: … Diet, Food, and Nutrition ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Products: … EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 3 ADET ... EVİGEN 300 MG/2 ML IM ENJEKSİYONLUK ÇÖZELTİ, 50 ADET …
Zinc chloride
Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Iupac: … zinc(2+) dichloride …
Matched Description: … chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and …
Matched Mixtures name: … AMINOMIX 2 SOLÜSYON, 1000 ML ... AMINOMIX 2 SOLÜSYON, 2000 ML ... AMINOMIX 1 NOVUM 1500 ML …
Matched Categories: … Blood and Blood Forming Organs ... Basic Ointments and Protectants ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Perioselect Zinc Chloride Solution 1% …
Matched Description: … chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and …
Matched Mixtures name: … AMINOMIX 2 SOLÜSYON, 1000 ML ... AMINOMIX 2 SOLÜSYON, 2000 ML ... AMINOMIX 1 NOVUM 1500 ML …
Matched Categories: … Blood and Blood Forming Organs ... Basic Ointments and Protectants ... Blood Substitutes and Perfusion Solutions ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Perioselect Zinc Chloride Solution 1% …
Aripiprazole
Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and...
Approved
Investigational
Matched Iupac: … 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one …
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs ... Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ARİPA 2 MG TABLET, 2 ADET ... ARİPA 2 MG TABLET, 7 ADET ... ARİPA 2 MG TABLET, 28 ADET …
Matched Description: … [L45859] Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A receptors and antagonism ... of alpha-adrenergic and 5-HT2A receptors. ... treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and …
Matched Categories: … Aripiprazole and prodrugs ... Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-1 Receptor Antagonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … ARİPA 2 MG TABLET, 2 ADET ... ARİPA 2 MG TABLET, 7 ADET ... ARİPA 2 MG TABLET, 28 ADET …
Tenofovir disoproxil
Tenofovir disoproxil fumarate (a prodrug of tenofovir), marketed by Gilead Sciences under the trade name Viread, belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs). This drug is prescribed in combination with other drugs for the management of HIV infection as well as for...
Approved
Investigational
Matched Iupac: … bis({[(propan-2-yloxy)carbonyl]oxy}methyl) {[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methanephosphonate …
Matched Salts cas: … 1453166-76-1 …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and efavirenz …
Matched Salts cas: … 1453166-76-1 …
Matched Mixtures name: … Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate ... Emtricitabine and Tenofovir Disoproxil Fumarate …
Matched Categories: … Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Tenofovir and prodrugs ... lamivudine and tenofovir disoproxil ... tenofovir disoproxil and emtricitabine ... lamivudine, tenofovir disoproxil and efavirenz …
Tezepelumab
Asthma is a heterogeneous chronic obstructive respiratory disease with both "type 2" (T2) and T2-low endotypes characterized by reduced airflow, chronic inflammation, and airway remodelling.[A243764, A243769] Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes. Blocking the...
Approved
Investigational
Matched Description: … Asthma is a heterogeneous chronic obstructive respiratory disease with both "type 2" (T2) and T2-low ... produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology. ... [A243764, A243769, A243774]
Tezepelumab is a human monoclonal IgG2λ antibody directed against TSLP …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Foreskin keratinocyte (neonatal)
Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical damage. It is composed of epidermal, dermal and hypodermal layers. The barrier function of the skin owed to its avascular epidermal layer, which is made mainly of keratinocytes. The keratinocytes form a...
Approved
Matched Description: … The defining moment in skin culture was in 1975 when Rheinwald and Green successfully grew human keratinocytes ... Skin, the largest organ of the human body, plays the main role in protecting the body from mechanical ... of [DB10770] and keratinocytes. …
Trifarotene
Trifarotene is a topical retinoid cream used in the treatment of acne vulgaris that was first approved for use in the United States in October 2019. Retinoids are a class of medications structurally and functionally analogous to vitamin A, though later generation retinoids such as trifarotene and adapalene bear little...
Approved
Investigational
Matched Iupac: … 3'-[3-tert-butyl-4-(pyrrolidin-1-yl)phenyl]-4'-(2-hydroxyethoxy)-[1,1'-biphenyl]-4-carboxylic acid …
Matched Description: … to vitamin A and are analogous only in function. ... [L9013] Retinoids are a class of medications structurally and functionally analogous to [vitamin A], ... though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Description: … to vitamin A and are analogous only in function. ... [L9013] Retinoids are a class of medications structurally and functionally analogous to [vitamin A], ... though later generation retinoids such as trifarotene and [adapalene] bear little structural resemblance …
Matched Categories: … Skin and Mucous Membrane Agents …
alpha-Tocopherol succinate
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the...
Approved
Nutraceutical
Vet approved
Matched Iupac: … 4-oxo-4-{[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6 …
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1- ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and …
Matched Mixtures name: … Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Master Key Multi Vitamin Multi Mineral Formula 2 ... Co-q10 and Vitamin E …
Matched Categories: … Diet, Food, and Nutrition ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Description: … Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet ... IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1- ... d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and …
Matched Mixtures name: … Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Master Key Multi Vitamin Multi Mineral Formula 2 ... Co-q10 and Vitamin E …
Matched Categories: … Diet, Food, and Nutrition ... Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Pegaspargase
Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia. Asparagine is an amino acid that is vital for cell survival. In humans, most normal tissues can produce asparagine through the action of asparagine synthetase. However, leukemia...
Approved
Investigational
Matched Description: … reducing immune detection, and it also increases the half-life of L-asparaginase. ... However, leukemia cells have low levels of this enzyme and depend on exogenous sources. ... Pegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Enzymes and Coenzymes ... Antineoplastic and Immunomodulating Agents …
Cupric oxide
Cupric oxide, or copper (II) oxide, is an inorganic compound with the chemical formula CuO. Cupric oxide is used as a precursor in many copper-containing products such as wood preservatives and ceramics. Cupric oxide may be found in over-the-counter vitamin-mineral supplements as a source of DB09130. The mean daily dietary...
Approved
Matched Iupac: … copper(2+) ion oxidandiide …
Matched Description: … Cupric oxide poses potential health and environmental concern due to toxic and mutagenic particles generating ... paints, and catalysts in organic synthesis [A32656]. ... The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [L2422]. …
Matched Mixtures name: … PNV Tabs 29-1 ... Trinatal Rx 1 ... PNV Tabs 29-1 …
Matched Categories: … Diet, Food, and Nutrition …
Matched Description: … Cupric oxide poses potential health and environmental concern due to toxic and mutagenic particles generating ... paints, and catalysts in organic synthesis [A32656]. ... The mean daily dietary intake of copper in adults ranges between 0.9 and 2.2 mg [L2422]. …
Matched Mixtures name: … PNV Tabs 29-1 ... Trinatal Rx 1 ... PNV Tabs 29-1 …
Matched Categories: … Diet, Food, and Nutrition …
Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous. Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.
Approved
Investigational
Matched Description: … Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999. ... belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Leflunomide and metabolite ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Leflunomide and metabolite ... Antineoplastic and Immunomodulating Agents …
Lutetium Lu-177 vipivotide tetraxetan
Lutetium Lu-177 vipivotide tetraxetan is a radioligand therapeutic agent. It consists of a radionuclide, lutetium Lu-177, linked to a moiety that binds to PSMA, a transmembrane protein that is expressed in prostate cancer. Lutetium Lu-177 vipivotide tetraxetan was first approved by the FDA on March 23, 2022 as a treatment...
Approved
Matched Iupac: … (177Lu)lutetium(3+) 2-[4,7-bis(carboxylatomethyl)-10-[({[(1r,4r)-4-{[(1S)-1-{[(5S)-5-carboxy-5-({[(1S ... ]methyl}carbamoyl)methyl]-1,4,7,10-tetraazacyclododecan-1-yl]acetate ... )-1,3-dicarboxypropyl]carbamoyl}amino)pentyl]carbamoyl}-2-(naphthalen-2-yl)ethyl]carbamoyl}cyclohexyl …
Matched Description: … [L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended …
Matched Products: … 1 Pluvicto …
Matched Description: … [L41290] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended …
Matched Products: … 1 Pluvicto …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Salts cas: … 6112-76-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Matched Salts cas: … 6112-76-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Zinc acetate
Approved
Investigational
Matched Iupac: … zinc(2+) diacetate …
Matched Mixtures name: … Up and Up itch relief ... Rugid Itch and Pain Relief ... Anti Itch and Skin Protectant …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Mixtures name: … Up and Up itch relief ... Rugid Itch and Pain Relief ... Anti Itch and Skin Protectant …
Matched Categories: … Alimentary Tract and Metabolism ... Various Alimentary Tract and Metabolism Products ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Etranacogene dezaparvovec
Hemophilia B - also called factor IX deficiency or Christmas disease - is an X-linked genetic disorder resulting in an absence or deficiency of clotting factor IX. Clotting factors, including factor IX, are necessary components of the signaling cascade responsible for blood clotting and subsequent wound healing. Symptoms of hemophilia...
Approved
Investigational
Matched Description: … the gain-of-function Padua variant of human Factor IX controlled by a liver-specific promotor 1. ... The therapy involves a one-time infusion of a viral vector carrying a codon-optimized DNA sequence of ... [L44186] In December 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended …
Matched Categories: … Cellular and Gene Therapy ... Blood and Blood Forming Organs …
Matched Categories: … Cellular and Gene Therapy ... Blood and Blood Forming Organs …
Displaying drugs 101 - 125 of 241 in total