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Displaying drugs 101 - 125 of 241 in total
Insulin degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A18561,A18562,A18563,A18564,A174934] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and Type 2 Diabetes. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... degludec is an ultra-long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... XULTOPHY 100U/ML+3.6MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin degludec and liraglutide ... insulin degludec and insulin aspart ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... TRESIBA FLEXTOUCH 100 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET ... TRESIBA FLEXTOUCH 200 U/ML ENJEKSIYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 1 ADET …
Pitavastatin, also known as the brand name product Livalo, is a lipid-lowering drug belonging to the statin class of medications. By inhibiting the endogenous production of cholesterol within the liver, statins lower abnormal cholesterol and lipid levels and ultimately reduce the risk of cardiovascular disease. More specifically, statin medications competitively...
Approved
Matched Iupac: … (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid …
Matched Description: … for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. ... coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks. ... lipid levels and ultimately reduce the risk of cardiovascular disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Trolise 1 mg Filmtabletten ... PITAMIN 1 MG EFERVESAN TABLET, 30 ADET ... PITAMIN 1 MG EFERVESAN TABLET, 90 ADET …
Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy. An adeno-associated virus is a small virus that infects humans and other primates. It is not pathogenic and it causes a very mild immune response. This type of virus is vastly used as vectors for gene therapy because they can...
Approved
Matched Description: … virus is the high predictability, unlike retrovirus, as they associate with a specific region of the human ... It is not pathogenic and it causes a very mild immune response. ... [L1094] An adeno-associated virus is a small virus that infects humans and other primates. …
Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of...
Approved
Matched Iupac: … 4-({6-amino-5-bromo-2-[(4-cyanophenyl)amino]pyrimidin-4-yl}oxy)-3,5-dimethylbenzonitrile …
Matched Description: … virus type 1 (HIV-1), and consequently blocks DNA-dependent and RNA-dependent polymerase activity. ... Etravirine does not inhibit human DNA polymerase alpha, beta or gamma. ... Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … and Type 2 Diabetes. ... [L34964] Insulin glargine is produced by recombinant DNA technology using a non-pathogenic laboratory ... Insulin glargine is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... insulin glargine and lixisenatide ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LANTUS 100 IU/ML SUBKUTAN KULLANIM İÇİN ENJEKSİYONLUK SOLÜSYON, 1 ADET ... BASAGLAR KWIKPEN 100 U/ML SC KULLANIM ICIN ENJEKSIYONLUK COZELTI ICEREN KULLANIMA HAZIR KALEM, 2 ADET …
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin ... [A180478] Dupilumab was generated by recombinant DNA technology in Chinese Hamster Ovary cell suspension ... under investigations for potential therapeutic use in diseases driven by allergic reactions or type 2
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... DUPİXENT 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 2 ADET ... Dupixent 175 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Enjektör, 1 ADET …
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Iupac: … 2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl furan-2-carboxylate ... (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-1-(2-chloroacetyl)-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1H, …
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and ... Mometasone furoate is formulated as a dry powder inhaler, nasal spray, and ointment for its different ... It has a glucocorticoid receptor binding affinity 22 times stronger than [dexamethasone] and higher than …
Matched Mixtures name: … M-FURO MANT % 0.1 + % 1 KREM, 20G ... M-FURO FA %0.1 + %2 KREM, 30 G ... MATEC 2/200 MCG INHALASYON TOZ IÇEREN KAPSÜL , 60 KAPSÜL …
Matched Categories: … formoterol and mometasone …
Matched Products: … Up and Up Allergy ... Nasonex Allergy and Congestion ... Nasal Allergy and Congestion Relief …
To date, ozenoxacin has been used in trials studying the treatment of impetigo. As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by Staphylococccus aureus or Streptococcus pyogenes in adult and pediatric patients...
Approved
Investigational
Matched Iupac: … 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic …
Matched Description: … *Staphylococccus aureus* or *Streptococcus pyogenes* in adult and pediatric patients 2 months of age ... s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by ... and older. …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Doravirine is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) intended to be administered in combination with other antiretroviral medicines.[L12729,L4562] Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and tenofovir disoproxil fumarate (300 mg). Doravirine is formally indicated for the treatment of...
Approved
Investigational
Matched Iupac: … 3-chloro-5-({1-[(4-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-1,2 …
Matched Description: … treatments available for the management of HIV-1 infection. ... no prior antiretroviral treatment experience, further expanding the possibility and choice of therapeutic ... Doravirine is available by itself or as a combination product of doravirine (100 mg), lamivudine (300 mg), and
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine, tenofovir disoproxil and doravirine ... Heterocyclic Compounds, 1-Ring …
CD55-deficient protein-losing enteropathy (PLE), or CHAPLE disease, is an ultra-rare hereditary disease, with fewer than 100 patients diagnosed worldwide or fewer than 10 patients in the US. The pathophysiology of this disease is mainly attributed to the deficiency of the CD55 protein, which is the main regulator of the complement...
Approved
Investigational
Matched Description: … [A261120] Pozelimab is a human, monoclonal immunoglobulin G4P antibody against the terminal ... cleavage of C3 and C5 respectively into immunoreactive peptides C3a and C5a. ... Under normal circumstances, CD55 inhibits the activity of C3 and C5 convertases, thus preventing the …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Synonyms: … (11β,16β)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione …
Matched Iupac: … 2-[(1R,2S,3aS,3bS,9aS,9bR,10S,11aS)-9b-chloro-10-hydroxy-2,9a,11a-trimethyl-7-oxo-1-(propanoyloxy)-1H ... ,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl propanoate …
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... formoterol, glycopyrronium bromide and beclometasone …
Matched Products: … RİNOMİL 100 MCG BURUN SPREYİ, SÜSPANSİYON, 1 ŞİŞE …
An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …
Matched Salts cas: … 63585-09-1
Matched Categories: … Pyrophosphate Analog DNA Polymerase Inhibitor …
The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary...
Approved
Investigational
Matched Description: … It was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion ... of lipids, and its absence or deficiency results in the accumulation of lipids in various organs. ... The lysosomal acid lipase (LAL) enzyme is found in lysosomes and is primarily responsible for the metabolism …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …
Matched Products: … KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION. …
Chromium is a transition element with the chemical symbol Cr and atomic number 24 that belongs to Group 6 of the periodic table. It is used in various chemical, industrial and manufacturing applications such as wood preservation and metallurgy. The uses of chromium compounds depend on the valency of chromium,...
Approved
Matched Description: … be human carcinogens [L1982]. ... Chromium picolinate capsules may be used as nutritional adjuvant in patients with or at risk of type 2 ... It is used in various chemical, industrial and manufacturing applications such as wood preservation and
Matched Mixtures name: … For-2 ... Spectrum 2 Cap ... Master Key Multi Vitamin Multi Mineral Formula 2
Matched Categories: … Diet, Food, and Nutrition …
Matched Products: … .-1 ... Wms 1 ... . #1 Supplement …
Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human coagulation FIX gene that was investigated as a potential treatment for hemophilia B. Hemophilia B is a rare X-linked genetic disorder characterized by abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to...
Approved
Investigational
Matched Description: … abnormal coagulation due to dysfunctional coagulation factor IX with a male incidence estimated to be 1 ... Fidanacogene elaparvovec is a liver-specific adeno-associated virus (AAV) vector containing a codon-optimized human ... 2–3 times a week for severe hemophilia, although this carries a significant financial burden to the …
Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B), a B cell survival factor. BLyS levels are often elevated in immunodeficient and autoimmune disorders, such as systemic lupus erythematosus (SLE).[A251495, L42705] By binding to...
Approved
Matched Description: … Belimumab is a fully human recombinant IgG1λ monoclonal antibody that inhibits soluble human B lymphocyte ... It is produced by recombinant DNA technology in a murine cell (NS0) expression system. ... [A251520] It is currently used to treat SLE and lupus nephritis.[L42630] …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … BENLYSTA 200 MG / 1 ML ... BENLYSTA SUBCUTÁNEO 200 MG / 1 ML ... BENLYSTA 400 MG IV INFUZYONLUK COZETI HAZIRLAMAK ICIN TOZ ICEREN FLAKON, 1 ADET …
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein, CD52. The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and complementarity-determining regions from a...
Approved
Investigational
Matched Description: … The Campath-1H antibody is an IgG1 kappa with the human variable framework and constant regions, and ... It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the ... [L43397] It is marketed as LEMTRADA for multiple sclerosis (MS) treatment and CAMPTAH for B-cell chronic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … MABCAMPATH INF SOL ICIN 30 MG/ML KONS 1 ML 3 FLK (10 MG/ML KONSANTRE 3 AMP) ... LEMTRADA 12 MG /1.2 ML İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET …
Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers, including mesothelioma, chronic lymphocytic leukemia (CLL), breast cancer, and small-cell lung cancer (SCLC). It is a derivative of the marine-derived agent ecteinascidin (trabectedin), an anticancer agent found in extracts of the tunicate...
Approved
Investigational
Matched Iupac: … (1R,2R,3R,11S,12S,14R,26R)-5,12-dihydroxy-6,6'-dimethoxy-7,21,30-trimethyl-27-oxo-2',3',4',9'-tetrahydro …
Matched Description: … Lurbinectedin is a DNA alkylating agent that has been investigated in the treatment of a variety of cancers ... including mesothelioma,[A214325] chronic lymphocytic leukemia (CLL),[A214328] breast cancer,[A214322] and ... [L14336] This accelerated approval is based on the rate and duration of therapeutic response observed …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Description: … and minimal toxicity. ... [A7514] The effect of this drug has no homology in human host cells, which gives it excellent tolerability ... Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration …
Matched Categories: … MATE 1 Inhibitors ... Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor ... Heterocyclic Compounds, 1-Ring ... lamivudine and dolutegravir ... dolutegravir and rilpivirine …
The AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2.[L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another...
Approved
Investigational
Matched Description: … SARS-CoV-2. ... as a potential vector for vaccines against another human coronavirus, Middle Eastern respiratory syndrome ... AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2. …
Matched Categories: … Vaccines, DNA
Ancestim is a non-glycosylated recombinant methionyl human stem cell factor. It is a 166 amino acid protein produced by E. coli with an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine . Ancestim was...
Approved
Investigational
Withdrawn
Matched Description: … Ancestim was developed by Amgen and sold to Biovitrium in December 2008. ... DNA sequence analysis, except for the addition of an N-terminal methionine[L1088]. ... It was submitted to the FDA under the status of recommendation for approval with a 10 to 1 votes. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Intercellular Signaling Peptides and Proteins …
Filgrastim is a short-acting recombinant, non-pegylated human granulocyte colony-stimulating factor (G-CSF) analog produced by recombinant DNA technology. It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in E. Coli. Human...
Approved
Matched Description: … 2, 2022. ... G-CSF) analog produced by recombinant DNA technology. ... [L40714] Human G-CSF is a glycoprotein that regulates the production and release of neutrophils from …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … ICEREN FLAKON, 1 ADET ... LEUCOSTIM 15 MIU SC/IV KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... LEUCOSTIM 30 MIU SC/IV KULLANIMA HAZIR ENJEKTOR/KUTU, 1 ADET …
Gout is a disease that occurs by the deposition of monosodium urate crystals (MSU) in body tissues, especially around joints . This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals . Allopurinol is a xanthine oxidase enzyme inhibitor that...
Approved
Matched Description: … This disease has been well-documented in historical medical records and appears in the biographies of ... It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [ ... enzyme inhibitor that is considered to be one of the most effective drugs used to decrease urate levels and
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. It is also produced by Malassezia furfur, also known as Pityrosporum ovale, which is a species of fungus that is normally found on human skin. Azelaic acid is effective against a number of skin conditions, such...
Approved
Matched Description: … furfur_, also known as _Pityrosporum ovale_, which is a species of fungus that is normally found on human ... Azelaic acid is a saturated dicarboxylic acid found naturally in wheat, rye, and barley. ... It works in part by stopping the growth of skin bacteria that cause acne, and by keeping skin pores clear …
Matched Mixtures name: … 2% Salicylic Acid FACIAL CLEANSER …
Matched Categories: … Skin and Mucous Membrane Agents …
Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.[L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be...
Approved
Matched Iupac: … 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-2-fluoro-N-methylbenzamide …
Matched Description: … [A252667,A252642] Due to a favorable pharmacological profile, a phase 1 study of enzalutamide was ... receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and ... A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents …
Displaying drugs 101 - 125 of 241 in total