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Displaying drugs 101 - 125 of 10312 in total

Quaternium-15

Quaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. In 2005,...
Approved
Experimental
Matched Description: … most frequently positive allergens identified in patch tests by the North American Contact Dermatitis Group ... contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin. ... It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause …

Hypochlorite

Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. Being unstable in the pure form, hypochlorite is most commonly used for bleaching, disinfectation, and water treatment purposes in its salt form, sodium hypochlorite. Hypochlorite is often used as a chemical reagent for chlorination and oxidation...
Approved
Matched Description: … Hypochlorite is an ion composed of chlorine and oxygen with the chemical formula ClO−. …
Matched Categories: … Anti-Infective Agents …

Clindamycin

Clindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. It has a relatively narrow spectrum of activity that includes anaerobic bacteria as well as gram-positive cocci and bacilli and gram-negative bacilli. Interestingly,...
Approved
Vet approved
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents ... Neurotoxic agents ... Agents that produce neuromuscular block (indirect) …
Matched Products: … Truemed Group LLC …

Rucaparib

Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however, it causes a unique effect of synthetic lethality. By targeting the genetically-mutated cancer...
Approved
Investigational
Matched Description: … [A249240] The drug was later approved by the European Commission in May 2018. ... PARP is an enzyme that plays an essential role in DNA repair. ... Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

2,2'-Dibenzothiazyl disulfide

2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic rubber and plastic regeneration. It is also a known allergen and dermatological sensitizer. Sensitivity to 2,2'-Dibenzothiazyl disulfide may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … 2,2'-Dibenzothiazyl disulfide is an accelerator used in the processing process for natural and synthetic …

Human cytomegalovirus immune globulin

Cytomegalovirus immunoglobulin is obtained from pooled adult human plasma selected for high titers of antibody for cytomegalovirus (CMV). It contains purified immunoglobulin G (IgG) antibodies targeting cytomegalovirus (CMV)[FDA label]. Cytomegalovirus, a member of the herpes virus family, is ubiquitous the human population, leading to infections which are followed by life-long...
Approved
Matched Description: … During the span of an individual's life, the virus may reactivate, resulting in repeated shedding and ... The seroprevalence of antibodies in adults ranges from 40-100 % with an inverse correlation to socioeconomic …

Dicyclomine

Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder and irritable bowel syndrome.[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small...
Approved
Matched Categories: … Synthetic Anticholinergics, Esters With Tertiary Amino Group ... Autonomic Agents ... Cholinergic Agents ... Anticholinergic Agents ... Agents producing tachycardia …

Riociguat

Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension)...
Approved
Matched Description: … Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other ... regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for …
Matched Categories: … Antihypertensive Agents ... Hypotensive Agents ... Vasodilating Agents …

Cinnamaldehyde

Cinnamaldehyde is a naturally occurring flavonoid that gives the spice cinnamon its flavour and odour. It occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum such as camphor and cassia. Sensitivity to cinnamaldehyde may be identified with a clinical patch test.
Approved
Experimental
Matched Categories: … Antimutagenic Agents ... Flavoring Agents ... Antineoplastic Agents ... Protective Agents ... Antineoplastic Agents, Phytogenic …

Hydroxycitronellal

Hydroxycitronellal is a synthetic fragrance that is widely used in many cosmetics and hygiene products such as deodorants, soaps, antiseptics, and other household items. It has the smell of lilac, lily, and lily of the valley . Hydroxycitronellal has also been shown to be a dermatologic irritant and allergen, and...
Approved
Experimental

Isoeugenol

Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental

Cefdinir

Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class. It has been proven to be effective for the treatment of common bacterial infections in the ear, sinus, throat, lungs, and skin. Cefdinir was approved by the FDA in 1997 to...
Approved
Matched Description: … Cefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially …
Matched Categories: … Anti-Bacterial Agents ... Anti-Infective Agents …

Sulpiride

Sulpiride first appeared in published literature in 1967. Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses. Sulpiride is not approved by the FDA, Health Canada, or the EMA; though...
Approved
Investigational
Matched Description: … [A229683] Sulpiride is not approved by the FDA, Health Canada, or the EMA; though it is approved in …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents, Second-Generation ... Dopamine Agents ... Antipsychotic Agents ... Neurotoxic agents …

Macitentan

Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH). It was first approved by the FDA in 2013. Macitentan differs from its predecessor bosentan in part due to its lower risk of hepatotoxicity. A combination product (Opsynvi) comprising macitentan and tadalafil was approved...
Approved
Matched Description: … [L35890] It was first approved by the FDA in 2013. ... [L39105] It was subsequently approved by the FDA in March 2024.[L50622] ... A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October …
Matched Categories: … Antihypertensive Agents ... Vasodilating Agents …

Lutein

Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. In green plants, xanthophylls act to modulate light energy and serve as...
Approved
Investigational
Nutraceutical
Matched Description: … In green plants, xanthophylls act to modulate light energy and serve as non-photochemical quenching agents ... Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids. ... to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very high …

Isocarboxazid

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription...
Approved
Matched Description: … was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved …
Matched Categories: … Antidepressive Agents ... Antidepressive Agents Indicated for Depression ... Serotonin Agents ... Hypotensive Agents ... Photosensitizing Agents …

Isosorbide

Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. It was approved by the FDA in 1980, but has since been discontinued. Currently, isosorbide is an organic nitrate currently available in the isosorbide mononitrate and isosorbide dinitrate forms, and is used for the prevention of...
Approved
Investigational
Matched Description: … It was approved by the FDA in 1980, but has since been discontinued. ... Isosorbide was previously available in an oral formulation for the reduction of intraocular pressure. ... Currently, isosorbide is an organic nitrate currently available in the [isosorbide mononitrate] and [ …
Matched Categories: … Antianginal Agents ... Natriuretic Agents ... Cardiovascular Agents ... Vasodilating Agents …

Tetraferric tricitrate decahydrate

Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia and iron deficiency anemia in adults with chronic kidney disease. Tetraferric tricitrate decahydrate was granted FDA approval on 5 September 2014.
Approved
Matched Description: … Tetraferric tricitrate decahydrate is an iron containing phosphate binder used to treat hyperphosphatemia …

Decitabine

Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying etiology and presentation, including neutropenia and thrombocytopenia. Further mutations leading to increased proliferation of cancerous cells can eventually lead to secondary acute myeloid leukemia, which has a poor prognosis.[A215082, A215092] Among treatment options, nucleoside analogues such as...
Approved
Investigational
Matched Description: … Myelodysplastic syndromes (MDS) are a heterogeneous group of hematopoietic neoplasms with variable underlying ... [L14962] It is also available as an oral combination product together with the cytidine deaminase inhibitor ... A2263, A2264, A2265, A215317, L14962] Decitabine was developed by MGI Pharma/SuperGen Inc. and was approved …
Matched Categories: … Antineoplastic Agents ... Myelosuppressive Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Neratinib

Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Approved
Investigational
Matched Description: … Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth …
Matched Categories: … Antineoplastic Agents ... Antineoplastic and Immunomodulating Agents …

Fecal microbiota

Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an FDA-approved option to prevent the recurrence of Clostridioides difficile infection (CDI) in patients given an antibacterial treatment for recurrent CDI.[A259182,L46217,L46222] Although the incidence of CDI has declined and the number of cases...
Approved
Investigational
Matched Description: … Fecal microbiota, given either as a rectal transplant or in an oral formulation of live spores, is an ... given an antibacterial treatment for recurrent CDI. ... FDA-approved option to prevent the recurrence of _Clostridioides difficile_ infection (CDI) in patients …
Matched Categories: … Miscellaneous Therapeutic Agents …

Fluoroestradiol F-18

Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen receptor-positive breast cancer lesions. The ability to image ER-positive tumors in vivo is advantageous in that, while helping to visualize tumor progression/regression, it may also be used to assess for heterogeneity in ER expression across...
Approved
Matched Description: … Fluoroestradiol F-18 is an imaging agent used with positron emission tomography (PET) to detect estrogen …

Natalizumab

Natalizumab is a recombinant humanized IgG4κ monoclonal antibody that binds to α4-integrin. While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it was withdrawn from the market following multiple reports of fatal progressive multifocal leukoencephalopathy (PML). In 2006, the FDA reintroduced the drug to the...
Approved
Investigational
Matched Description: … [L48041] Natalizumab was approved by the European Commission on September 22, 2023.[L49096] ... [L48041] While natalizumab was originally approved by the FDA to treat multiple sclerosis in 2004, it ... [A261326] Natalizumab was further approved by the FDA for the treatment of Crohn's Disease in January …
Matched Categories: … Immunomodulatory Agents ... Immunosuppressive Agents ... Antineoplastic and Immunomodulating Agents …

Levothyroxine

Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Categories: … Agents used to treat hypothyroidism …

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Categories: … Protective Agents ... Cryoprotective Agents …
Matched Products: … An Adc Egf Wrinkle Eye ... An Adc Sp Intensive Wrinkle Eye ... Pro Radiance Renascent An Infinite Energizer …
Displaying drugs 101 - 125 of 10312 in total