Displaying drugs 1301 - 1325 of 1900 in total
RGX-111
RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. Developed by REGENXBIO Inc., it was investigated for the treatment of mucopolysaccharidosis Type I (MPS I).
Investigational
Matched Synonyms: … Adeno-associated virus vector serotype 9 expressing human a-L-iduronidase …
Matched Description: … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
Matched Description: … RGX-111 is an adeno-associated virus vector AAV9 designed to deliver the α-L-iduronidase (IDUA) gene. …
Permethrin
A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.
Approved
Investigational
Matched Description: … A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. ... It is a yellow to light orange-brown, low melt-ing solid or viscous liquid. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Hydrocarbons, Cyclic ... Drugs that are Mainly Renally Excreted …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Scabicides, Insecticides and Repellents ... Hydrocarbons, Cyclic ... Drugs that are Mainly Renally Excreted …
Matched Products: … A Scabs ... A-LICES LOTION 1%w/w …
Secnidazole
Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa ... to form a radical anion, thereby damaging and killing the target pathogen. ... improved oral absorption and a longer terminal elimination half-life than other drugs in this class. …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... azithromycin, fluconazole and secnidazole …
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... azithromycin, fluconazole and secnidazole …
Matched Products: … SECNICHEN POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL ... SECNIDAZOL PPS (POLVO PARA RECONSTITUIR A SUSPENSIÓN) ... SECNIPEN 750 MG POLVO PARA RECOSTRUIR A SUSPENSION ORAL …
IFx-Hu2.0
IFx-Hu2.0 is an investigational cancer vaccine. It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a cationic polymer.
Investigational
Matched Synonyms: … Immunotherapeutic vaccine consisting of pAc/emm55, a plasmid DNA (pDNA), which codes for a modified immunogenic …
Matched Description: … IFx-Hu2.0 is an investigational cancer vaccine. ... It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Matched Description: … IFx-Hu2.0 is an investigational cancer vaccine. ... It is composed of plasmid DNA encoding the streptococcal membrane protein, Emm55, contained within a …
Dordaviprone
Dordaviprone (ONC-201) is under investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma).
Investigational
Matched Synonyms: … 2,4,6,7,8,9-Hexahydro-4-((2-methylphenyl)methyl)-7-phenylmethyl)imidazo)(1,2-a)pyrido(3,4-e)pyrimidin ... 7-benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo(1,2-A)pyrido(3,4-E)pyrimidin-5(4H)-one …
Matched Description: … investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and …
Matched Description: … investigation in clinical trial NCT03394027 (ONC201 in Recurrent/Refractory Metastatic Breast Cancer and …
Dupilumab
Dupilumab is a fully human monoclonal antibody of the immunoglobulin G4 subclass that binds to the interleukin-4 (IL-4) receptor, inhibiting the receptor signaling pathways. As an interleukin-4 receptor alpha antagonist, dupilumab inhibits the signaling of pro-inflammatory cytokines, called interleukins (IL), that induce inflammatory and immunological reactions in several atopic or...
Approved
Investigational
Matched Description: … atopic or allergic conditions, such as eczema, allergic reaction, and rhinosinusitis. ... with nasal polyposis, and eosinophilic esophagitis. ... pediatric atopic dermatitis, and chronic obstructive pulmonary disease. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Skin and Mucous Membrane Agents …
Matched Products: … DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 300 mg/2ml ... DUPIXENT SOLUTION FOR INJECTION IN A PRE-FILLED SYRINGE 200 mg/1.14ml …
Amlodipine
Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched International brands: … Atecard-AM …
Matched Description: … associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... Amlodipine is commonly used in the treatment of high blood pressure and angina. …
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... aliskiren and amlodipine ... losartan and amlodipine ... benazepril and amlodipine …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG ... A-B VASK 5 …
Matched Description: … associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than ... Amlodipine has antioxidant properties and an ability to enhance the production of nitric oxide (NO), ... Amlodipine is commonly used in the treatment of high blood pressure and angina. …
Matched Mixtures name: … AMLODIPINE and VALSARTAN ... Amlodipine and Valsartan ... Amlodipine and Valsartan …
Matched Categories: … ACE Inhibitors and Calcium Channel Blockers ... nebivolol and amlodipine ... aliskiren and amlodipine ... losartan and amlodipine ... benazepril and amlodipine …
Matched Products: … AMLODIGAMMA TOP 5MG ... AMLODIGAMMA TOP 10MG ... A-B VASK 5 …
Agalsidase alfa
Agalsidase alfa is a recombinant human α-galactosidase A similar to agalsidase beta. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater benefit with agalsidase beta.[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa,...
Approved
Matched Synonyms: … alpha-galactosidase A ... Recombinant alpha-galactosidase A …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... While patients generally do not experience a clinically significant difference in outcomes between the ... A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Description: … Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. ... While patients generally do not experience a clinically significant difference in outcomes between the ... A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Nortriptyline
Nortriptyline hydrochloride, the active metabolite of amitriptyline, is a tricyclic antidepressant (TCA). It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.
Approved
Matched Synonyms: … 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine ... 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Hydrocarbons, Cyclic ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Ava-nortriptyline ... Apo-nortriptyline ... APO-NORTRIPTYLINE CAPSULE 25 mg …
Matched Description: … and other conditions. ... [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain ... Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant …
Matched Categories: … Tricyclics and Other Norepinephrine-reuptake Inhibitors ... Hydrocarbons, Cyclic ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index …
Matched Products: … Ava-nortriptyline ... Apo-nortriptyline ... APO-NORTRIPTYLINE CAPSULE 25 mg …
Lyme disease vaccine (recombinant OspA)
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as...
Approved
Withdrawn
Matched Synonyms: … Lipoprotein outer surface a borrelia burgdorferi antigen …
Matched Description: … It is conjugated with alum (aluminum hydroxide) as an adjuvant. ... sensu stricto ZS7, as expressed by Escherichia coli. ... Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi …
Matched Description: … It is conjugated with alum (aluminum hydroxide) as an adjuvant. ... sensu stricto ZS7, as expressed by Escherichia coli. ... Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi …
Estazolam
A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.
Approved
Illicit
Matched Synonyms: … 8-chloro-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Drugs that are Mainly Renally Excreted …
Matched Description: … A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives ... Drugs that are Mainly Renally Excreted …
Mimopezil
Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease. Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A.
Investigational
Matched Synonyms: … N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A …
Matched Description: … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. ... Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment …
Matched Description: … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A. ... Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment …
Esmirtazapine
Esmirtazapine, known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and vasomotor symptoms associated with menopause. Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors. Merck has...
Investigational
Matched Synonyms: … (S)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors ... known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and ... Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. …
Matched Description: … This includes inverse agonist activity of H1 and 5-HT2 receptors and antagonism of α2-adrenergic receptors ... known by the standardized identifier SCH 900265, was under development by Organon to treat insomnia and ... Esmirtazapine is the (S)-(+)-enantiomer of mirtazapine and possesses similar overall pharmacology. …
Eluvixtamab
Investigational
Matched Synonyms: … A cd33/cd3 bispecific t-cell engager antibody for acute myeloid leukemia therapy …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Collagenase clostridium histolyticum
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and Peyronie's disease. The topical formulation is used for the debridement of necrotic tissue due to burns or chronic ulcers. On July 6,...
Approved
Investigational
Matched Synonyms: … Clostridiopeptidase A …
Matched Description: … [L14872] Also known as Qwo, this injection is the first approved injectable treatment for cellulite and ... It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and ... Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. …
Matched Categories: … Enzymes and Coenzymes ... Skin and Mucous Membrane Agents ... Preparations for Treatment of Wounds and Ulcers …
Matched Description: … [L14872] Also known as Qwo, this injection is the first approved injectable treatment for cellulite and ... It is beneficial in the breakdown of collagen plaques for the treatment of Dupuytren's contracture and ... Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum. …
Matched Categories: … Enzymes and Coenzymes ... Skin and Mucous Membrane Agents ... Preparations for Treatment of Wounds and Ulcers …
Insulin detemir
Insulin detemir is a long-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.[A2358, A2359, A2360, A44] Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta...
Approved
Matched Description: … 1 and Type 2 Diabetes. ... of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal ... , and inhibits lipolysis and proteolysis among many other functions. …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levemir FlexPen 100U/ML Solution for injection in a prefilled pen …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levemir FlexPen 100U/ML Solution for injection in a prefilled pen …
Nitrous oxide
Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as...
Approved
Vet approved
Matched Description: … At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste ... It is used in surgery and dentistry for its anesthetic and analgesic effects. ... its recreational use as an inhalant drug. …
Matched Products: … N/A ... AZOTO PROTOSSIDO AIR LIQUIDE SANITA' ... Stickoxydul medizinisch Air Liquide …
Matched Products: … N/A ... AZOTO PROTOSSIDO AIR LIQUIDE SANITA' ... Stickoxydul medizinisch Air Liquide …
Carbon dioxide
Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms. Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may...
Approved
Investigational
Vet approved
Matched Description: … during bodily investigations, to inflate body cavities during surgery (such as key-hole surgery), and ... in solid form (dry ice) for freezing of tissue and removal of warts. ... Medical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. ... Carbon Dioxide-Air Mixture ... Carbon Dioxide, Air …
Matched Products: … N/A ... Carbon Dioxide Air ... Carbon Dioxide Air Mixture …
Matched Mixtures name: … Carbon Dioxide and Oxygen Mixture, Compressed, Oxidizing, N.O.S. ... Carbon Dioxide-Air Mixture ... Carbon Dioxide, Air …
Matched Products: … N/A ... Carbon Dioxide Air ... Carbon Dioxide Air Mixture …
20-Hydroxyecdysone
Investigational
Matched Synonyms: … Polypodin a ... Polypodine a …
Matched Iupac: … 2,3,6-trihydroxy-6-methylheptan-2-yl]-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Iupac: … 2,3,6-trihydroxy-6-methylheptan-2-yl]-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …
Exaluren
Investigational
Matched Synonyms: … 6-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine ... 6'-(R)-Methyl-5-O-(5-amino-5,6-dideoxy-a-L-talofuranosyl)-paromamine …
Gemcitabine
Gemcitabine is a nucleoside analog and a chemotherapeutic agent. It was originally investigated for its antiviral effects, but it is now used as an anticancer therapy for various cancers. Gemcitabine is a cytidine analog with two fluorine atoms replacing the hydroxyl on the ribose. As a prodrug, gemcitabine is transformed...
Approved
Matched Description: … Gemcitabine is a nucleoside analog and a chemotherapeutic agent. ... [A233140]
Gemcitabine is marketed as Gemzar and it is available as intravenous injection. ... [L32960] The structure, metabolism, and mechanism of action of gemcitabine are similar to [cytarabine …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... Drugs that are Mainly Renally Excreted ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Aj-gemcitabine ... Act Gemcitabine ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides ... Drugs that are Mainly Renally Excreted ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … Aj-gemcitabine ... Act Gemcitabine ... PAMIGEN® 200MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCIONINYECTABLE …
Alirocumab
Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of diet and statin treatment. It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which...
Approved
Matched Description: … diet and statin treatment. ... FDA approval was contingent on the completion of further clinical trials to better determine efficacy and ... for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML ... PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 150 MG/ML …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML ... PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 150 MG/ML …
DCP-001
Investigational
Matched Synonyms: … Proliferation arrested myelomonocytic leukemic cell line-derived cells with a mature dendritic cell phenotype …
Tinodasertib
Investigational
Matched Synonyms: … 4-{6-[4-(morpholine-4-carbonyl)phenyl]imidazo[1,2- a]pyridin-3-yl}benzonitrile …
Displaying drugs 1301 - 1325 of 1900 in total