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Displaying drugs 126 - 150 of 9612 in total

Crotamiton

Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.
Approved
Matched Products: … CROPITON(R) …

Perflubutane

Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis, Portal Hypertension, and Peripheral Artery Disease. It is a cardiovascular drug designed to enable ultrasound to compete more effectively with nuclear stress testing; currently the leading procedure for detecting coronary heart disease.
Approved
Investigational
Matched Description: … Perflubutane has been used in trials studying the diagnostic of Liver Mass, Liver Diseases, Liver Metastasis …
Matched Categories: … Diagnostic Uses of Chemicals …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … (L) form may antagonize the effects of the dextrorotatory isomer. ... Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain ... Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory …
Matched Mixtures name: … Central-vite 18 Essential ... Harvest Of Values All B Complex Tab ... Herbs of Gold B Complex Plus Softgel …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Description: … of NSF thanks to the macrocyclic structures that limit dechelation of gadolinium. ... contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of ... [A7001] Like other GBCA, gadobutrol usage carries the risk of nephrogenic systemic fibrosis (NSF) …
Matched Categories: … Diagnostic Uses of Chemicals …

Strontium ranelate

Strontium ranelate, a strontium (II) salt of ranelic acid, is a medication for osteoporosis. Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the knee. This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts and,...
Approved
Withdrawn
Matched Description: … Some reports have shown that strontium ranelate can slow down the progression of osteoarthritis of the ... intrinsic bone tissue quality and microarchitecture in osteoporosis by way of a number of cellular and ... This agent presents an atypical mechanism of action in which it increases deposition of new bone by osteoblasts …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Technetium Tc-99m pertechnetate

Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with the chemical formula TcO4-. Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to a similar extent as iodine. It also concentrates in the thyroid gland, salivary glands, gastric mucosa,...
Approved
Investigational
Matched Description: … Technetium Tc-99m pertechnetate is a radiopharmaceutical diagnostic agent composed of an oxoanion with ... Pertechnetate has a wide variety of uses within nuclear medicine as it distributes within the body to ... Currently marketed as the product Drytec, technetium-99m pertechnetate is indicated for imaging of the …
Matched Categories: … Diagnostic Uses of Chemicals …

Reslizumab

Reslizumab is a humanized interleukin-5 (IL-5) antagonist monoclonal antibody (IgG4 kappa) that is produced by recombinant DNA technology in murine myeloma non-secreting 0 (NS0) cells. IL-5 is a pro-inflammatory cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of eosinophils [FDA Label]. Elevated levels of eosinophils...
Approved
Investigational
Matched Description: … and nonallergic forms of asthma where eosinophilia is prominent. ... cytokine that is responsible for the growth and differentiation, recruitment, activation, and survival of ... Elevated levels of eosinophils increase the risk for asthma exacerbations, including both allergic forms …

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing ... was first approved by the FDA in the 1970s but withdrawn within approximately 5 years due to a lack of …

Torasemide

Torasemide is a high-ceiling loop diuretic. Structurally, it is a pyridine-sulfonylurea used as an antihypertensive agent. Torasemide was first approved for clinical use by the FDA in 1993.
Approved
Matched Categories: … combinations of sulfonamides ... Increased Diuresis at Loop of Henle …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Description: … Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... [L47291] Used in the management of pain, tapentadol is typically reserved for patients who have limited …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Tetracaine

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Approved
Vet approved
Matched Mixtures name: … Dermacaine-R …
Matched Categories: … Esters of Aminobenzoic Acid ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …

Inositol

Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol. Myo-inositol is the cis-1,2,3,5-trans-4,6-cyclohexanehexol and it is prepared from an aqueous extract of corn kernels by precipitation and hydrolysis of crude phytate. These molecules have structural...
Approved
Investigational
Withdrawn
Matched Description: … the most common type of inositol, myo-inositol. ... corn kernels by precipitation and hydrolysis of crude phytate. ... Inositol is a collection of nine different stereoisomers but the name is usually used to describe only …
Matched Mixtures name: … Harvest Of Values All B Complex Tab …

Lasofoxifene

Lasofoxifene is a non-steroidal 3rd generation selective estrogen receptor modulator (SERM) that selectively binds to both ERα and ERβ with high affinity. It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment of vaginal atrophy. It was initially developed as Oporia by Pfizer as...
Approved
Investigational
Matched Description: … of vaginal atrophy. ... It is a naphthalene derivative marketed for prevention and treatment of osteoporosis and for the treatment ... signed a license agreement with Sermonix Pharmaceuticals for the development and commercialization of …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Technetium Tc-99m tetrofosmin

Technetium Tc-99m tetrofosmin is a drug used in nuclear myocardial perfusion imaging. The radioisotope, technetium-99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of diphosphines and which are referred to as tetrofosmin. It is a lipophilic technetium phosphine dioxo cation that was formulated into a freeze-dried kit...
Approved
Matched Description: … 99m, is chelated by two 1,2-bis[di-(2-ethoxyethyl)phosphino]ethane ligands which belong to the group of …
Matched Categories: … Diagnostic Uses of Chemicals …

Plecanatide

Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Description: … to 18 years of age ... Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation ... It should not be used in children less than six years of age, and should be avoided in patients six years …

Sodium citrate

Sodium citrate is the sodium salt of citric acid. It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. From the medical point of view, it is used as alkalinizing...
Approved
Investigational
Matched Description: … Sodium citrate is the sodium salt of citric acid. ... It has been indicated for the treatment of metabolic acidosis. ... From the medical point of view, it is used as alkalinizing agent. …
Matched Mixtures name: … Reveos Select CPD/AS-5 Red Cell Preservative For Collection Of Blood ... IMUFLEX WB-RP Blood Bag System with Integral Whole Blood Leukocyte Reduction Filter (Removing Platelets …

Rezafungin

Rezafungin is an echinocandin antifungal drug.[A258393,L45633] Unlike other echinocandins such as caspofungin and micafungin, rezafungin has long‐acting pharmacokinetics and a high stability that allows for it to have long dosing intervals maintaining high plasma exposure. Rezafungin has a half-life higher than 130 hours and can be administered once a week...
Approved
Investigational
Matched Iupac: … 22E,24S,25S,26S)-6-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-5,8,11,17,20,23,25-heptahydroxy-18 …
Matched Description: … Rezafungin has a half-life higher than 130 hours and can be administered once a week instead of daily ... [A258403] In March 2023, the FDA approved rezafungin for injection for the treatment of candidemia and ... L45633] Clinical studies have shown that rezafungin is non-inferior to caspofungin for the treatment of …

Cyclacillin

A cyclohexylamido analog of penicillanic acid.
Approved
Matched Description: … A cyclohexylamido analog of penicillanic acid. …
Matched Categories: … combinations of penicillins …

Meglumine

Approved
Matched Categories: … Diagnostic Uses of Chemicals …

Gadoversetamide

Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.
Approved
Investigational
Matched Description: … gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of …
Matched Categories: … Diagnostic Uses of Chemicals …

Secnidazole

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-life than other drugs in this class. Secnidazole is selective against many anaerobic Gram-positive and Gram-negative bacteria as well as protozoa. Once...
Approved
Matched Description: … A245508] In September 2017, FDA approved secnidazole under the market name Solosec for the treatment of …
Matched Products: … GIAFAR(R) 1 G TABLETAS ... DAKSOL(R)1 G TABLETAS …

Burosumab

Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood. ... children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Pamidronic acid

Pamidronic acid is a second generation, nitrogen containing bisphosphonate similar to neridronic acid and alendronic acid. Pamidronic acid was first described in the literature in 1977. The second generation bisphosphonates are less common as third generation bisphosphonates, such as ibandronic acid, zoledronic acid, minodronic acid, and risedronic acid are becoming...
Approved
Matched Categories: … Drugs for Treatment of Bone Diseases …

Zoledronic acid

Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Description: … of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone. ... [A203111] Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia …
Matched Categories: … Drugs for Treatment of Bone Diseases …

Chikungunya vaccine (live, attenuated)

Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952. It is spread primarily by the bite of infected mosquitos of the Aedes genus. Infection with CHIKV causes chikungunya fever, an illness characterized by acute fever and severe, persistent arthralgia. Prior to...
Approved
Matched Description: … [L48726] It is approved for use in patients 18 years of age and older who are at high-risk of exposure ... [A262051] It is spread primarily by the bite of infected mosquitos of the _Aedes_ genus. ... Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in …
Displaying drugs 126 - 150 of 9612 in total