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Displaying drugs 126 - 150 of 14777 in total

Guanidine

A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is...
Approved
Matched Description: … of myasthenia and as a fluorescent probe in HPLC. ... (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment …
Matched Salts name: … Guanidine hydrochloride …
Matched Products: … Guanidine hydrochloride …

Tolazoline

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Salts name: … Tolazoline hydrochloride …
Matched Categories: … Topical Products for Joint and Muscular Pain …
Matched Products: … Priscoline hydrochloride …

Methylphenidate

Methylphenidate is a central nervous system stimulant used most commonly in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) and for narcolepsy. Also known as the marketed products Ritalin, Concerta, or Biphentin, methylphenidate is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve the following group of developmentally...
Approved
Investigational
Matched Description: … and working memory. ... the most effective and widely used treatment for ADHD, and are considered first-line options for children ... addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and …
Matched Salts name: … Methylphenidate hydrochloride …
Matched Categories: … Methylphenidate and isomer ... Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Methylphenidate Hydrochloride ... Methylphenidate hydrochloride ... Methylphenidate Hydrochloride SR …

Tiagabine

Tiagabine is an anti-convulsive medication. It is also used in the treatment for panic disorder as are a few other anticonvulsants. Though the exact mechanism by which tiagabine exerts its effect on the human body is unknown, it does appear to operate as a selective GABA reuptake inhibitor.
Approved
Investigational
Matched Salts name: … Tiagabine hydrochloride …
Matched Categories: … Nipecotic Acid and Derivatives …
Matched Products: … Tiagabine Hydrochloride …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Salts name: … Benzphetamine hydrochloride …
Matched Products: … Benzphetamine Hydrochloride …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Salts name: … Loxapine hydrochloride …
Matched Categories: … Diazepines, Oxazepines, Thiazepines and Oxepines …
Matched Products: … Loxapine Hydrochloride Im Injection 50mg/ml ... Loxapine Hydrochloride Oral Concentrate 25mg/ml …

Ethambutol

Ethambutol is a bacteriostatic agent indicated alongside medications such as isoniazid, rifampin, and pyrazinamide in the treatment of pulmonary tuberculosis. Ethambutol was first described in the literature in 1961. It was developed out of a need for therapies active against isoniazid resistant strains of Mycobacterium tuberculosis. Ethambutol was granted FDA...
Approved
Matched Description: … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and …
Matched Salts name: … Ethambutol hydrochloride …
Matched Categories: … ethambutol and isoniazid ... rifampicin, ethambutol and isoniazid ... rifampicin, pyrazinamide, ethambutol and isoniazid …
Matched Products: … Ethambutol Hydrochloride ... ETHAMBUTOL HYDROCHLORIDE …

Bentonite

Approved
Matched Categories: … Silicon Compounds …

Parecoxib

Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Description: … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. ... Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Dynastat Powder and Solvent for Solution for Injection 40mg …

Guanfacine

Guanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension but is now indicated as an extended release tablet for the treatment of ADHD. Guanfacine was first described in the literature in 1974. Guanfacine was granted FDA approval on 27 October 1986.
Approved
Investigational
Matched Salts name: … Guanfacine hydrochloride …
Matched Products: … Guanfacine hydrochloride ... Guanfacine Hydrochloride …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Foster and Thrive Gentle Laxative …

Leuprolide

Leuprolide is a synthetic 9-residue peptide analogue of gonadotropin-releasing hormone (GnRH). Unlike the endogenous decapeptide GnRH, leuprolide contains a single D-amino acid (D-leucyl) residue, which helps to increase its circulating half-life from three to four minutes to approximately three hours. As a GnRH mimic, leuprolide is capable of binding to...
Approved
Investigational
Matched Description: … downstream modulation of both gonadotropin hormone and sex steroid levels. ... [A203222] As a GnRH mimic, leuprolide is capable of binding to the GnRH receptor (GnRHR) and inducing ... [L13850] Since this initial approval, various long-acting intramuscular and subcutaneous products have …
Matched Categories: … Hormones and Related Agents ... Amino Acids, Peptides, and Proteins ... leuprorelin and bicalutamide ... Antineoplastic and Immunomodulating Agents …
Matched Products: … POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 45mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 7.5mg ... POWDER AND SOLVENT FOR SOLUTION FOR INJECTION 22.5mg …

Melphalan

Melphalan is a nitrogen mustard or bischloroethylamine type alkylating agent. It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard.[A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. It is also used for high-conditioning before hematopoietic stem...
Approved
Matched Description: … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma. …
Matched Salts name: … Melphalan hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Products: … Melphalan Hydrochloride ... Melphalan hydrochloride …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Description: … Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961[A185039] and has been …
Matched Salts name: … Cyclobenzaprine hydrochloride …
Matched Products: … Cyclobenzaprine Hydrochloride ... Cyclobenzaprine hydrochloride …

Encainide

All drug products containing encainide hydrochloride. Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack. The manufacturer of Enkaid capsules voluntarily withdrew the product from the US market on December 16, 1991.
Approved
Investigational
Withdrawn
Matched Description: … All drug products containing encainide hydrochloride. ... Encainide hydrochloride, formerly marketed as Enkaid capsules, was associated with increased death rates …
Matched Salts name: … Encainide hydrochloride …

Tioconazole

Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In...
Approved
Matched Description: … Tioconazole is an imidazole antifungal used to treat fungal and yeast infections. ... Topical formulations are used for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus …
Matched Salts name: … Tioconazole hydrochloride …
Matched Categories: … Imidazole and Triazole Derivatives ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Metabolic Side Effects of Drugs and Substances ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Up and up tioconazole 1 ... Foster and Thrive Tioconazole …

Saxagliptin

Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Mixtures name: … Saxagliptin and Metformin Hydrochloride ... Saxagliptin and Metformin Hydrochloride ... Saxagliptin and Metformin Hydrochloride …
Matched Salts name: … Saxagliptin hydrochloride ... Saxagliptin hydrochloride dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and saxagliptin ... Amino Acids, Peptides, and Proteins ... saxagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …

Alogliptin

Alogliptin is a selective, orally-bioavailable inhibitor of enzymatic activity of dipeptidyl peptidase-4 (DPP-4). Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer. FDA approved January 25, 2013.
Approved
Matched Description: … Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (> …
Matched Mixtures name: … Alogliptin and Metformin Hydrochloride ... Alogliptin and Metformin Hydrochloride ... Alogliptin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... metformin and alogliptin ... pioglitazone and alogliptin ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Lurasidone

Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States.
Approved
Investigational
Matched Description: … Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently …
Matched Salts name: … Lurasidone hydrochloride …
Matched Products: … Lurasidone Hydrochloride ... Lurasidone hydrochloride …

Betahistine

Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. It has a significant impact on both the physical and social functioning of affected individuals.[A220318,L16408] Betahistine is a histamine-like antivertigo drug used for treating symptoms associated with Ménière's disease. It is thought to...
Approved
Investigational
Matched Iupac: … methyl[2-(pyridin-2-yl)ethyl]amine …
Matched Description: … It has a significant impact on both the physical and social functioning of affected individuals. ... Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing …
Matched Salts name: … Betahistine hydrochloride …
Matched Products: … BETAHISTINE HYDROCHLORIDE …

Sodium zirconium cyclosilicate

Sodium zirconium cyclosilicate is approved as the trade product Lokelma developed by AstraZeneca - an insoluble, non-absorbed sodium zirconium silicate, formulated as a powder for oral suspension that acts as a highly selective potassium removing agent. It is administered orally and is odorless, tasteless, and stable at room temperature. Approval...
Approved
Investigational
Matched Description: … [L2933] It is administered orally and is odorless, tasteless, and stable at room temperature. ... Approval of the medication is supported by data from three double-blind, placebo-controlled trials and ... two open-label trials which showed that the onset of action was approximately 1.0 hour and the median …
Matched Categories: … Silicon Compounds ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Description: … Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may ... Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer. …
Matched Mixtures name: … Potassium and Iodine Tab ... Potassium and Iodine Tab ... Essential Vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition ... Herbs and Natural Products ... Antiseptics and Disinfectants …
Matched Products: … XENETIX 300-50ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ ... XENETIX 300-100ML SOLN FOR INTRAVASCULAR, INTRAUTERINE AND INTRA-ARTICULAR INJ …

Minoxidil

A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Approved
Investigational
Matched Description: … potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Minoxidil ... Up and Up minoxidil ... Berkley and Jensen Minoxidil …

Nalbuphine

A narcotic used as a pain medication. It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Approved
Matched Description: … It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid …
Matched Salts name: … Nalbuphine hydrochloride …
Matched Products: … Nalbuphine Hydrochloride …

Methylcellulose

Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and emulsifier for foodstuffs and cosmetics. The Degree of Substitution (DS) of a given form of methyl cellulose is defined as the average number of substituted hydroxyl groups per glucose with a theoretical maximum of 3,...
Approved
Matched Description: … emulsifier for foodstuffs and cosmetics. ... Like cellulose, it is not digestible, not toxic, and not allergenic ... Methyl cellulose polymer consisting of numerous linked glucose molecules used as a stabiliser, thickener and …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Fiber Laxative 188 …
Displaying drugs 126 - 150 of 14777 in total