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Displaying drugs 1551 - 1575 of 1989 in total

Nitazoxanide

Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment of...
Approved
Investigational
Vet approved
Matched Description: … proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic ... Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and ... children and may also be considered in the treatment of illnesses caused by other protozoa or helminths …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents …
Matched Products: … TAKINOX® 100 ... VIBATRIN® 100 MG / 5 ML ... ZELIX® 100 MG/ 5 ML …

Bedaquiline

Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Description: … The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated ... the current standard of TB treatment of anti-TB drugs for 2 months, including 2 key drugs [isoniazid] and ... [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and …
Matched Products: … SIRTURO 100 MG ... SIRTURO 100MG TABLETS ... SIRTURO 100 MG TABLET, 24 ADET …

Mefenamic acid

A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
Approved
Matched Description: … A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … ACIDO MEFENAMICO TABLETAS X 500 MG ... ACIDO MEFENAMICO X 500 MG. TABLETAS …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … developed with slower onsets and longer durations of action. ... [A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature ... [A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been …
Matched Mixtures name: … Seaford Nifedipine and Lidocaine Hydrochloride Cream ... BETA - NICARDIA CAPSULE ... Adalat XL Plus …
Matched Categories: … Beta blocking agents and calcium channel blockers ... Calcium Channel Blockers and Diuretics ... Calcium-Regulating Hormones and Agents ... atenolol and nifedipine ... nifedipine and diuretics …
Matched Products: … Procardia XL ... Nifedical XL ... NifedicalXL XL …

Modafinil

Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by modafinil. The prexin neuron activation is associated...
Approved
Investigational
Matched Description: … lead to an increase in extracellular dopamine. ... Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants ... Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides …
Matched Categories: … Modafinil and isomer ... Metabolic Side Effects of Drugs and Substances ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … VIGIA® 100 MG ... CARIM 100 MG ... Modasomil 100 mg Tabletten …

Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester

Experimental
Matched Name: … Sulfamic Acid 2,3-O-(1-Methylethylidene)-4,5-O-Sulfonyl-Beta-Fructopyranose Ester …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Description: … that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and ... [L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. ... In contrast to other PDE5 inhibitors like [sildenafil], tadalafil has greater selectivity for PDE5 and …
Matched Categories: … Genito Urinary System and Sex Hormones ... ambrisentan and tadalafil ... tamsulosin and tadalafil ... finasteride and tadalafil ... macitentan and tadalafil …
Matched Products: … TADALAFIL BETA PAH 20MG ... TADALAFILO X 20MG ... TENSAL® TABLETAS RECUBIERTAS X 20 MG …

Bismuth subcitrate potassium

A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD).
Approved
Investigational
Matched Description: … A bismuth compound used for peptic ulcer and gastro-oesophageal reflux disease (GORD). …
Matched Mixtures name: … Bismuth Subcitrate Potassium, Metronidazole and Tetracycline Hydrochloride ... Bismuth Subcitrate Potassium, Metronidazole, and Tetracycline Hydrochloride ... KATACOLD 120 MG + 3.75 MG+ l MG /5 ML PEDIYATRIK ŞURUP, 100 ML …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) ... bismuth subcitrate, tetracycline and metronidazole …
Matched Products: … KAF 7,5 MG / 5 ML SURUP, 100 ML ... KREVAL7.5 MG/5 ML ŞURUP, 100 ML ... CODACTIV M 15 MG/5 ML ŞURUP, 100 ML …

Sotatercept

Sotatercept is an activin signalling inhibitor. It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain. On March 26, 2024, sotatercept was approved by the FDA for the treatment of pulmonary arterial hypertension...
Approved
Investigational
Matched Synonyms: … PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100 ... PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100 …
Matched Description: … [L50361] Sotatercept works to resolve the imbalance in activin–growth differentiation factor and BMP …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Dexmedetomidine

An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Approved
Vet approved
Matched Description: … An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and …
Matched Categories: … Hypnotics and Sedatives ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … PRECEDEX® 400MCG/100ML (4MCG/ML) ... REDEXA ® DEXMEDETOMIDINA 100 MCG /ML POR 2 ML ... SEMOTİDİN 400 MCG/100 ML IV İNFÜZYONLUK ÇÖZELTİ, 1 ADET …

Avanafil

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Description: … other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both [sildenafil] and …
Matched Categories: … Genito Urinary System and Sex Hormones …
Matched Products: … ANIME® 100 ... SPEDRA TABLET 100MG ... Spedra 100mg Tablets …

Irinotecan

Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Description: … This leads to the arrest of the cell cycle in the S-G2 phase and cancer cell death.[A263376] ... Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking ... irinotecan was first commercially available in Japan in 1994 to treat various cancers such as lung, cervical and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … ไอริน็อกซ์ 100 ... IRINOCAN 100 CONCENTRATE FOR SOLUTION FOR INFUSION 100 MG/ 5 ML ... TARCKORIN ® 100MG …

Ioflupane F-18

Investigational
Matched Synonyms: … 18f-beta-cit-fp ... 18f-fp-.beta.-cit …

Phosphopantothenic acid

Experimental
Matched Synonyms: … .beta.-alanine, n-((2r)-2-hydroxy-3,3-dimethyl-1-oxo-4-(phosphonooxy)butyl)- …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Nabumetone

Nabumetone was originally developed as a non-acidic non-steroidal anti-inflammatory drug (NSAID).[label] It was thought to avoid trapping of the drug in the stomach by making it unable to dissociate into ions which was believed to reduce GI toxicity by limiting local action. While slightly reduced, possibly due to a degree...
Approved
Matched Description: … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Nabumetone 1000 mg …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … It is also used for hypnosis and for the control of convulsive states. ... Small doses have been shown to be anti-analgesic and lower the pain threshold. ... It does not produce any excitation but has poor analgesic and muscle relaxant properties. …
Matched Categories: … Hypnotics and Sedatives …
Matched Products: … ไธโอเพน 1000 …

Fusidic acid

An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis. It is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections.
Approved
Investigational
Matched Description: … tablets and injections. ... It is often used topically in creams and eyedrops but is available in systemic formulations including …
Matched Mixtures name: … BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream …
Matched Products: … AFUSIL TOPIC® ... FUCITHALMIC VISCOUS EYE-DROPS …

Candesartan cilexetil

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …
Matched Products: … CANDESARTANTABLETAS X 8 MG ... CANDESARTANTABLETAS X 16 MG ... CANDESARTAN TABLETAS X 16 MG …

Medroxyprogesterone acetate

Medroxyprogesterone acetate (MPA) is a progesterone derivative that is more resistant to metabolism for improved pharmacokinetic properties. MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also...
Approved
Investigational
Matched Description: … in palliative care for endometrial and renal carcinoma. ... endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and ... vaginal atrophy, prevent pregnancy, manage pain in endometriosis, prevent pregnancy, and is also used …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Combination Contraceptives (with Estrogen and derivatives) ... Hormones and Related Agents ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones …
Matched Products: … Provera 100mg Tablets ... MEDROXIPROGESTERONA ACETATO X 5 MG. …

Acitretin

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Description: … It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared …
Matched Categories: … Skin and Mucous Membrane Agents …
Matched Products: … NEOTIGASON 10 MG KAPSUL, 100 ADET ... NEOTIGASON 25 MG KAPSUL, 100 ADET ... PSÖRETİN 10 MG SERT KAPSÜL ,100 ADET …

Sitagliptin

Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256]. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255]....
Approved
Investigational
Matched Description: … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon ... Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise …
Matched Mixtures name: … JANUMET XR TABLET 100MG/1000MG ... Reddy-sitagliptin and Metformin Hydrochloride ... Reddy-sitagliptin and Metformin Hydrochloride …
Matched Categories: … Alimentary Tract and Metabolism ... sitagliptin and simvastatin ... metformin and sitagliptin ... sitagliptin and ertugliflozin ... sitagliptin and dapagliflozin …
Matched Products: … จิมเวีย 100 ... 100 mg tablet ... DIASIT 100 (Sitagliptin Film Coated Tablets 100mg) …

Light mineral oil

Approved
Matched Mixtures name: … Dermavive Shower and Bath Oil ... Aveeno N.S. Colloidal Oatmeal&M.O.B.T.-pwr ... Soothe XP …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Light Mineral Oil 100% Nf ... Sterile Light Mineral Oil 100% …

Carboplatin

Carboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma. Early clinical studies of carboplatin were performed in 1982. Carboplatin was developed as an analog of cisplatin with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.
Approved
Matched Iupac: … 7,7-diamino-6,8-dioxa-7-platinaspiro[3.5]nonane-5,9-dione …
Matched Description: … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Indicators and Reagents …
Matched Products: … CARBODEX 1000 MG/100 ML IV INFÜZYONLUK COZELTİ ICEREN FLAKON, 1 ADET ... CARBOPLATIN-KOCAK 1000 MG/100 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON …

Letrozole

Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.[A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like exemestane and anastrozole, meaning it does not significantly affect cortisol, aldosterone, and thyroxine. Letrozole was granted FDA approval on 25 July 1997.
Approved
Investigational
Matched Description: … ], meaning it does not significantly affect cortisol, aldosterone, and thyroxine. ... [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … LETROZOL BETA 2.5MG FTA …

Hemoglobin crosfumaril

Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Experimental
Matched Synonyms: … Hemoglobin A0 (human alpha2 beta2 tetrameric subunit), alpha-chain 99,99'-diamide with (E)-2-butenoic …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Displaying drugs 1551 - 1575 of 1989 in total