Displaying drugs 151 - 175 of 9455 in total
Azacitidine
Azacitidine is a pyrimidine nucleoside analogue with anti-neoplastic activity. It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine. One of them is the induction of cytotoxicity. As an analogue of cytidine, it...
Approved
Investigational
Matched Synonyms: … 4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Matched Iupac: … 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one …
Metipranolol
A beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Approved
Matched Synonyms: … Acetic acid 4-(2-hydroxy-3-isopropylamino-propoxy)-2,3,6-trimethyl-phenyl ester …
Matched Iupac: … 4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}-2,3,6-trimethylphenyl acetate …
Matched Iupac: … 4-{2-hydroxy-3-[(propan-2-yl)amino]propoxy}-2,3,6-trimethylphenyl acetate …
Linagliptin
Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes . Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, is not primarily eliminated by the renal system, and obeys concentration dependant protein binding . Linagliptin was approved by...
Approved
Matched Synonyms: … (R)-8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes ... Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, …
Matched Mixtures name: … กลีแซมบี 10 มก./5 มก. ... GLYXAMBI® 10 MG/ 5 MG ... GLYXAMBI® 10 MG/ 5 MG …
Matched Iupac: … 8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-2,3,6,7 …
Matched Description: … Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes ... Linagliptin differs from other DPP-4 inhibitors in that it has a non-linear pharmacokinetic profile, …
Matched Mixtures name: … กลีแซมบี 10 มก./5 มก. ... GLYXAMBI® 10 MG/ 5 MG ... GLYXAMBI® 10 MG/ 5 MG …
Tolbutamide
Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin...
Approved
Investigational
Matched Synonyms: … 3-(p-Tolyl-4-sulfonyl)-1-butylurea ... N-(4-Methylphenylsulfonyl)-N'-butylurea ... N-(4-Methylbenzenesulfonyl)-N'-butylurea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Matched Iupac: … 3-butyl-1-(4-methylbenzenesulfonyl)urea …
Lomefloxacin
Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Synonyms: … (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid ... 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Pirenzepine
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also...
Approved
Matched Synonyms: … 11-((4-Methyl-1-piperazinyl)acetyl)-5,11-dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one …
Matched Iupac: … -hexaen-10-one ... 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Matched Iupac: … -hexaen-10-one ... 2-[2-(4-methylpiperazin-1-yl)acetyl]-2,4,9-triazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13 …
Nisoldipine
Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nisoldipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Nisoldipine may be used in alone...
Approved
Matched Synonyms: … isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Iupac: … 3-methyl 5-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Disperse Blue 106
Disperse Blue 106 is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 5-Nitro-2-(2-methyl-4-(N-ethyl-N-(2-hydroxyethyl)amino)phenylazo)thiazole …
Matched Iupac: … 2-[ethyl({3-methyl-4-[(E)-2-(5-nitro-1,3-thiazol-2-yl)diazen-1-yl]phenyl})amino]ethan-1-ol …
Matched Iupac: … 2-[ethyl({3-methyl-4-[(E)-2-(5-nitro-1,3-thiazol-2-yl)diazen-1-yl]phenyl})amino]ethan-1-ol …
Celiprolol
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Synonyms: … RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea …
Matched Iupac: … 1-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-3,3-diethylurea …
Matched Iupac: … 1-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-3,3-diethylurea …
Famciclovir
Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). Famciclovir is a prodrug of penciclovir with higher oral bioavailability.
Approved
Investigational
Matched Synonyms: … 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine ... acetic acid 2-acetoxymethyl-4-(2-amino-purin-9-yl)-butyl ester …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Matched Iupac: … 2-[(acetyloxy)methyl]-4-(2-amino-9H-purin-9-yl)butyl acetate …
Padimate O
Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Iupac: … 2-ethylhexyl 4-(dimethylamino)benzoate …
Matched Mixtures name: … Vichy-lait Solaire SPF 10 ... Ulta Tanning SPF 4 ... Kroger SPF 4 Tanning Oil …
Matched Products: … Green Tea and Ginkgo Moisturizer SPF 10 ... Blue Green Algae With Grape Seed Extract Moisturizer SPF 10 ... Lip Balm Sunscreen SPF 4 Original …
Matched Mixtures name: … Vichy-lait Solaire SPF 10 ... Ulta Tanning SPF 4 ... Kroger SPF 4 Tanning Oil …
Matched Products: … Green Tea and Ginkgo Moisturizer SPF 10 ... Blue Green Algae With Grape Seed Extract Moisturizer SPF 10 ... Lip Balm Sunscreen SPF 4 Original …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Synonyms: … 17alpha-Caproyloxypregn-4-ene-3,20-dione …
Matched Description: … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention …
Matched Description: … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention …
Phloxine B
Phloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing tablets. These tablets allow patients to visualise areas where more brushing and...
Approved
Matched Synonyms: … Disodium 2',4',5',7'-tetrabromo-4,5,6,7-tetrachlorofluorescein …
Flavoxate
A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Approved
Matched Synonyms: … 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate ... 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylate …
Matched Iupac: … 2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate …
Matched Iupac: … 2-(piperidin-1-yl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate …
Tetracycline
Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria. It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site. It also binds to some extent to the...
Approved
Vet approved
Withdrawn
Matched Synonyms: … (4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Matched Iupac: … (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene …
Perindopril
Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Mixtures name: … PERAM 4 MG/10 MG TABLET,30 ADET ... PERINDOPRIL IND RAT 4/1.25 ... PERINDOPRIL IND RAT 4/1.25 …
Matched Products: … COVERSYL ARGININE 10 MG ... อะเซอทิล อาร์จินีน 10 มก. ... COVERSYL 10 MG FILM TABLET, 30 ADET …
Matched Products: … COVERSYL ARGININE 10 MG ... อะเซอทิล อาร์จินีน 10 มก. ... COVERSYL 10 MG FILM TABLET, 30 ADET …
Ethionamide
A second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Approved
Matched Synonyms: … 2-ethyl-4-thiopyridylamide …
Matched Iupac: … 2-ethylpyridine-4-carbothioamide …
Matched Iupac: … 2-ethylpyridine-4-carbothioamide …
Chlorambucil
A nitrogen mustard alkylating agent used as antineoplastic agent for the treatment of various malignant and nonmalignant diseases. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Approved
Matched Synonyms: … 4-(p-bis(beta-chloroethyl)aminophenyl)butyric acid ... 4-(p-bis(β-chloroethyl)aminophenyl)butyric acid ... 4-[p-[bis(2-chloroethyl)amino]phenyl]butyric acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Matched Iupac: … 4-{4-[bis(2-chloroethyl)amino]phenyl}butanoic acid …
Emtricitabine
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults or combined with tenofovir alafenamide for the prevention of HIV-1 infection in high risk adolescents and adults. Emtricitabine is a cytidine analogue. The drug works by inhibiting HIV reverse transcriptase, preventing transcription of...
Approved
Investigational
Matched Synonyms: … (−)-cis-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one ... (2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone ... 4-Amino-5-fluoro-1-((2R,5S)-2-hydroxymethyl-[1,3]oxathiolan-5-yl)-1H-pyrimidin-2-one …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Mixtures name: … DESCOVY (200/10 MG) ... DESCOVY FILM COATED TABLET 200 MG/10 MG ... DESCOVY 200 MG/ 10 MG FILM KAPLI TABLET, 30 ADET …
Matched Iupac: … 5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-4-imino-1,4-dihydropyrimidin-2-ol …
Matched Mixtures name: … DESCOVY (200/10 MG) ... DESCOVY FILM COATED TABLET 200 MG/10 MG ... DESCOVY 200 MG/ 10 MG FILM KAPLI TABLET, 30 ADET …
Resmetirom
Resmetirom is a thyroid hormone receptor-beta (THR-beta) agonist. On March 14, 2024, it was approved by the FDA as the first treatment of liver fibrosis due to noncirrhotic non-alcoholic steatohepatitis (NASH), which is a form of non-alcoholic fatty liver disease (NAFLD). Thyroid hormones directly regulate lipid metabolism in the liver;...
Approved
Investigational
Matched Synonyms: … 1,2,4-Triazine-6-carbonitrile, 2-[3,5-dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl] ... 2-[3,5-Dichloro-4-[[1,6-dihydro-5-(1-methylethyl)-6-oxo-3-pyridazinyl]oxy]phenyl]-2,3,4,5-tetrahydro- …
Matched Iupac: … 2-(3,5-dichloro-4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro …
Matched Iupac: … 2-(3,5-dichloro-4-{[6-oxo-5-(propan-2-yl)-1,6-dihydropyridazin-3-yl]oxy}phenyl)-3,5-dioxo-2,3,4,5-tetrahydro …
Nevirapine
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one …
Matched Iupac: … 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10- …
Matched Iupac: … 2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10- …
Phentolamine
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Synonyms: … 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …
Masoprocol
A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism. The compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem]
Approved
Investigational
Matched Synonyms: … meso-4-[4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Matched Iupac: … 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Matched Iupac: … 4-[(2S,3R)-4-(3,4-dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol …
Clomifene
A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.
Approved
Investigational
Matched Synonyms: … 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine …
Matched Iupac: … {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine …
Matched Products: … KLOMEN 50 MG TABLET, 10 ADET …
Matched Iupac: … {2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine …
Matched Products: … KLOMEN 50 MG TABLET, 10 ADET …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … EDTA, ion(4-) ... (ethylenedinitrilo)tetraacetic acid, ion(4−) …
Displaying drugs 151 - 175 of 9455 in total