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Displaying drugs 151 - 175 of 11997 in total

Procarbazine

An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone (the MOPP protocol) in the treatment of Hodgkin's disease.
Approved
Investigational
Matched Description: … (the MOPP protocol) in the treatment of Hodgkin's disease. ... An antineoplastic agent used primarily in combination with mechlorethamine, vincristine, and prednisone …

Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking...
Approved
Investigational
Matched Description: … acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in ... By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth …

Phenylephrine

Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Description: … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s ... [A187376] Phenylephrine was granted FDA approval in 1939.[L9413] …
Matched Mixtures name: … Zotex-C ... Dimetapp-C ... Novahistex C …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … PHENYLALPHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 50MCG/ML ... Phenylephrin Aguettant 50 Mikrogramm/ml Injektionslösung in einer Fertigspritze …

Lypressin

Approved
Matched Iupac: … -5,8,11,14,17-pentaene-4-carbonyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-N-[(C-hydroxycarbonimidoyl ... )ethyl]-7-[(C-hydroxycarbonimidoyl)methyl]-16-[(4-hydroxyphenyl)methyl]-1,2-dithia-5,8,11,14,17-pentaazacycloicosa ... 2S)-6-amino-2-({[(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-13-benzyl-6,9,12,15,18-pentahydroxy-10-[2-(C-hydroxycarbonimidoyl …

Durlobactam

Durlobactam is a diazabicyclooctane non-beta-lactam, beta-lactamase inhibitor. It is typically given in combination with sulbactam to protect it from degradation by certain serine-beta-lactamases. The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023. It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial...
Approved
Investigational
Matched Description: … [L47336] The combination product of durlobactam and sulbactam was first approved by the FDA in May 2023 ... It is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases …

Cefoxitin

Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Description: … It is derived from cephamycin C, which is produced by Streptomyces lactamdurans. …

Polyethylene glycol

Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.[A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water molecules per one PEG molecule. Molecular weights of PEGs vary...
Approved
Vet approved
Matched Description: … [L11812] PEG 3350 is also used for cleansing of the colon in preparation for colonoscopy in adults. ... PEGs have various applications in many fields, ranging from medical to industrial areas. ... [A190975,A190978] PEGs are water-soluble polymers that can form hydrogen bonds in a ratio of 100 water …
Matched Mixtures name: … GaviLyte - C TM …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Mix-In Laxative Packets …

Iron sucrose

Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with ... Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease …

Crizotinib

Crizotinib is a tyrosine kinase receptor inhibitor used for the treatment of anaplastic lymphoma kinase (ALK) or ROS1-positive non-small cell lung cancer (NSCLC) tumors, as well as ALK-positive anaplastic large cell lymphoma (ALCL) and inflammatory myofibroblastic tumor (IMT). By targeting the echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion protein, crizotinib offers...
Approved
Investigational
Matched Description: … treating NSCLC in patients with this type of rearrangement. ... [A250785] Crizotinib was the first-in-class drug used to treat ALK-positive tumors. ... [A250785] Crizotinib was approved by the FDA in 2011, and its use is accompanied by FDA-approved tests …

Baricitinib

Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. By inhibiting the actions of JAK1 and JAK2, baricitinib attenuates JAK-mediated inflammation and immune responses. Baricitinib was...
Approved
Investigational
Matched Description: … of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018. ... the use of baricitinib for the treatment of COVID-19 in May 2022. ... Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis. …

Melatonin

Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Description: … The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone ... rates in night workers. ... In mammals, melatonin is produced by the pineal gland. …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Glutamic acid

A peptide that is a homopolymer of glutamic acid.
Approved
Nutraceutical
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …

Vildagliptin

Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme. It is used to manage type II diabetes mellitus, where GLP-1 secretion and insulinotropic effects are impaired. By inhibiting DPP-4, vildagliptin prevents the degradation of glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP),...
Approved
Investigational
Matched Description: … of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea ... [L32813] Vildagliptin is currently under investigation in the US. ... Elevated levels of GLP-1 and GIP consequently results in improved glycemic control. …
Matched Categories: … Drugs Used in Diabetes …

Osilodrostat

Osilodrostat is an inhibitor of 11β-hydroxylase (also referred to as CYP11B1), the enzyme that catalyzes the final step in the biosynthesis of endogenous cortisol. It is used to lower circulating cortisol levels in the treatment of Cushing's disease, a disorder in which cortisol levels are chronically and supraphysiologically elevated. Cushing's...
Approved
Investigational
Matched Iupac: … 3-fluoro-4-[(5R)-5H,6H,7H-pyrrolo[1,2-c]imidazol-5-yl]benzonitrile …
Matched Description: … [A191850] Osilodrostat was approved for use in the EU in January 2020 for the treatment of endogenous ... Cushing's disease),[A191850] and was granted FDA approval and Orphan Drug designation in the US in March ... in which cortisol levels are chronically and supraphysiologically elevated. …

Methionine

A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
Approved
Nutraceutical
Matched Description: … A sulfur containing essential amino acid that is important in many body functions. …
Matched Mixtures name: … Aminosyn II in Dextrose ... Aminosyn II in Dextrose ... Aminosyn II in Dextrose …

Corynebacterium diphtheriae

Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … *Corynebacterium diphtheriae* toxin is extracted from the pathogenic actinobacterium *C. diphtheriae* ... The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants …
Matched Mixtures name: … Boostrix Injektionssuspension in einer Fertigspritze ... Boostrix Polio - Injektionssuspension in einer Fertigspritze ... Menjugate 10 Mikrogramm Injektionssuspension in einer Fertigspritze …

Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen

Approved

Citrus bioflavonoids

Approved
Experimental
Matched Mixtures name: … NAT-C ... KORDEL`S C TIME ACID FREE C 1000MG TABLET ... Special C …

Soybean oil

Derived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. It is a complex mixture of triglycerides where per 100 g, soybean oil has 16 g of saturated fat, 23 g of monounsaturated fat, and 58 g of polyunsaturated fat. The...
Approved
Matched Description: … It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. …

Nilutamide

Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors). Consequently, Nilutamide blocks the action of androgens of adrenal and testicular origin that stimulate the growth of...
Approved
Investigational
Matched Description: … Nilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. …

Indocyanine green

Approved
Experimental
Matched Categories: … Compounds used in a research, industrial, or household setting …

Pindolol

Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. Early research into the use of pindolol found it had chronotropic effects, and so further investigation focused on the treatment of arrhythmia. Research into pindolol's use in the treatment of hypertension began in the early 1970s....
Approved
Investigational
Matched Description: … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s. ... Pindolol is a first generation non-selective beta blocker used in the treatment of hypertension. …

Interferon alfa-n3

Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational

Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed ... In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated …

Pantothenic acid

Pantothenic acid, also called pantothenate or vitamin B5 (a B vitamin), is a water-soluble vitamin discovered by Roger J. Williams in 1919. For many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats....
Approved
Nutraceutical
Vet approved
Matched Description: … Williams in 1919. ... Small quantities of pantothenic acid are found in nearly every food, with high amounts in whole-grain ... Pantothenic acid is an ingredient in some hair and skin care products. …
Matched Mixtures name: … Virt-C DHA ... Taron-C DHA ... Zintrexyl-C …
Displaying drugs 151 - 175 of 11997 in total