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Displaying drugs 1851 - 1875 of 7740 in total
Ouabain
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like digitalis. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-exchanging ATPase.
Approved
Matched Iupac: … methyloxan-2-yl]oxy}-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... 10R,11aR)-3a,5a,9,10-tetrahydroxy-9a-(hydroxymethyl)-11a-methyl-7-{[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6- …
Sulindac
Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid class that is marketed by Merck under the brand name Clinoril. Like other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo...
Approved
Investigational
Matched Synonyms: … cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid ... (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid ... cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 …
Matched Iupac: … 2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid …
Matched Description: … is thought to primarily mediate its action by inhibiting prostaglandin synthesis by inhibiting COX-1 …
Thiabendazole
2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Approved
Vet approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Diazoxide
Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. Diazoxide is commonly used in the treatment of hyperinsulinaemic hypoglycemia due to its ability to inhibit insulin release....
Approved
Capromab pendetide
Capromab is a Murine IgG1 monoclonal 7E11-C5.3 antibody that recognizes prostate specific membrane antigen (PSMA – also known as glutamate carboxypeptidase 2) from prostate cancer cells and normal prostate tissue. When linked to pendetide, capromab is used as a chelating agent for the radionuclide Indium In-111 during imaging to evaluate...
Approved
Pyridoxal phosphate
This is the active form of vitamin B6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (pyridoxamine).
Approved
Investigational
Nutraceutical
Matched Iupac: … [(4-formyl-5-hydroxy-6-methylpyridin-3-yl)methoxy]phosphonic acid …
Matched Salts cas: … 41468-25-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Salts cas: … 41468-25-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Estrone
Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol. It is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione....
Approved
Matched Iupac: … 3bR,9bS,11aS)-7-hydroxy-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1- …
Oxaliplatin
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. Compared to cisplatin the two amine groups are replaced by diamino cyclohexane (DACH) group to provide a greater antitumor effect. However, this leads to poorer water solubility, which was compensated by the addition of the chloride...
Approved
Investigational
Matched Products: … ICEREN FLAKON, 1 ADET ... ICEREN FLAKON, 1 ADET ... PLOXAL-S 50 MG 5 MG/10 ML 1 IV INF. ICIN KON.COZ. ICEREN FLAKON, 1 ADET …
Afamelanotide
Afamelanotide is a first-in-class, synthetic, 13-amino acid peptide analogue of the endogenous alpha melanocyte-stimulating hormone (α-MSH). It differs structurally from its endogenous counterpart by only two amino acids - these structural differences improve biological efficacy by imparting a greater affinity for its target and a longer biological half-life.[A187202,A187205] Afamelanotide is...
Approved
Investigational
Matched Synonyms: … Melanotan 1 ... Melanotan-1 …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl …
Matched Categories: … Melanocortin 1 Receptor (MC1-R) Agonists …
Matched Iupac: … (4S)-4-{[(1S)-1-{[(1R)-1-{[(1S)-1-{[(1S)-1-[({[(2S)-6-amino-1-[(2S)-2-{[(1S)-1-carbamoyl-2-methylpropyl ... ]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]carbamoyl …
Matched Categories: … Melanocortin 1 Receptor (MC1-R) Agonists …
Cabazitaxel
Cabazitaxel is a taxoid synthesized from 10-deacetylbaccatin III, a compound isolated from the yew tree. As a second-generation semisynthetic microtubule inhibitor, cabazitaxel stabilizes microtubules and induces tumour cell death. Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to...
Approved
Matched Synonyms: … 1-HYDROXY-7.BETA.,10.BETA.-DIMETHOXY-9-OXO-5.BETA.,20-EPOXYTAX-11-ENE-2.ALPHA.,4,13.ALPHA. …
Matched Iupac: … 12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1- ... hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec …
Matched Products: … JEVTANA 60MG/1,5ML INFÜZYONLUK KONSANTRE ÇÖZELTI VE ÇÖZÜCÜ, 1 ADET VE 1 ÇÖZÜCÜ ... CABATAX 60 MG/1,5 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NEUTAXAN 60 MG/ 1.5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Iupac: … 12R,15S)-4-(acetyloxy)-15-{[(2R,3S)-3-{[(tert-butoxy)carbonyl]amino}-2-hydroxy-3-phenylpropanoyl]oxy}-1- ... hydroxy-9,12-dimethoxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0^{3,10}.0^{4,7}]heptadec …
Matched Products: … JEVTANA 60MG/1,5ML INFÜZYONLUK KONSANTRE ÇÖZELTI VE ÇÖZÜCÜ, 1 ADET VE 1 ÇÖZÜCÜ ... CABATAX 60 MG/1,5 ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NEUTAXAN 60 MG/ 1.5 ML İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Chlorpromazine
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
Approved
Investigational
Vet approved
Matched Synonyms: … 3-(2-chlorophenothiazin-10-yl)-N,N-dimethyl-propan-1-amine ... 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethyl-1-propanamine …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Matched Categories: … Adrenergic alpha-1 Receptor Antagonists …
Trastuzumab emtansine
Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent, DM1. T-DM1 combines two strategies-- anti-HER2 activity and targeted intracellular delivery of the potent anti-microtubule agent, DM1 (a maytansine derivative)--to produce cell cycle arrest and apoptosis....
Approved
Investigational
Matched Description: … have already used taxane and/or trastuzumab for metastatic disease or had their cancer recur within 6 …
Resorcinol
Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works...
Approved
Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Synonyms: … (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone …
Matched Iupac: … 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one …
Matched Iupac: … 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one …
Erdafitinib
In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Iupac: … N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-{2-[(propan-2-yl)amino]ethyl}quinoxalin-6-amine …
Metronidazole
Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics. It is frequently used to treat gastrointestinal infections as well as trichomoniasis and giardiasis, and amebiasis which are parasitic infections.[A181036,A181039] Metronidazole has been used as an antibiotic for several decades , with added antiparasitic properties that set...
Approved
Matched Synonyms: … 1-(2-hydroxy-1-ethyl)-2-methyl-5-nitroimidazole ... 2-methyl-5-nitroimidazole-1-ethanol ... 1-(β-oxyethyl)-2-methyl-5-nitroimidazole …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% ... Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Metrogel 1% …
Matched Iupac: … 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethan-1-ol …
Matched Mixtures name: … Ivermectin 1% / Metronidazole 1% ... Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... 171083 Ivermectin 1% / Metronidazole 1% / Niacinamide 4% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Metrogel 1% …
Propyl alcohol
A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
Approved
Matched Synonyms: … 1-propanol ... 1-proponol …
Matched Iupac: … propan-1-ol …
Matched Iupac: … propan-1-ol …
Camphor
Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Mixtures name: … VICKS VAPORUB BUHARLASAN MERHEM, 1 ADET ... VİCKS İNHALER 415,4 MG + 415,4 MG/1 G BURUN ÇUBUĞU …
Matched Products: … CBD Clinic Deep-Rub Pain Relief - Level 1 …
Matched Products: … CBD Clinic Deep-Rub Pain Relief - Level 1 …
Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) …
Iophendylate
Iophendylate is a mixture of isomers used as contrast medium, mainly for brain and spinal cord visualization. Iophendylate is a myelographic oil-ester (U.S. Patent 2,348,231). Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1-2cc) for locating spinal tumors. It next appeared on...
Approved
Matched Description: … Iophendylate, which was never shown to be safe, was initially introduced for use in small amounts (1- …
Thiamine
Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays...
Approved
Investigational
Nutraceutical
Vet approved
Matched Synonyms: … thiamine(1+) ... thiamine(1+) ion …
Matched Salts cas: … 59-43-8 ... 67-03-8 …
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) ... B 6 Plus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … B-1 Caps 500mg ... Vitamin B-1 100 Mg Tablets ... VITAMIN B 1 INJEKTOP 25MG …
Matched Salts cas: … 59-43-8 ... 67-03-8 …
Matched Mixtures name: … HEPATAMINE %8 500 ML(SETLI) ... HEPATAMINE %8 500 ML(SETSIZ) ... B 6 Plus …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … B-1 Caps 500mg ... Vitamin B-1 100 Mg Tablets ... VITAMIN B 1 INJEKTOP 25MG …
Isoeugenol
Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang. It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by...
Approved
Experimental
Matched Synonyms: … 2-methoxy-4-(prop-1-en-1-yl)phenol ... 1-Hydroxy-2-methoxy-4-propen-1-ylbenzene …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Matched Iupac: … 2-methoxy-4-(prop-1-en-1-yl)phenol …
Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated)
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Investigational
Idoxuridine
An analog of deoxyuridine that inhibits viral DNA synthesis. The drug is used as an antiviral agent.
Approved
Investigational
Matched Synonyms: … 1-beta-D-2'-Deoxyribofuranosyl-5-iodouracil ... 1-(2-Deoxy-beta-D-ribofuranosyl)-5-iodouracil …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2,3,4-tetrahydropyrimidine-2,4-dione …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Streptomycin
Streptomycin, an antibiotic derived from Streptomyces griseus, was the first aminoglycoside to be discovered and used in practice in the 1940s.[A233325,A233390] Selman Waksman and eventually Albert Schatz were recognized with the Nobel Prize in Medicine for their discovery of streptomycin and its antibacterial activity.[A233325,A232294] Although streptomycin was the first antibiotic...
Approved
Vet approved
Matched Iupac: … N-[(1S,2R,3R,4S,5R,6R)-3-carbamimidamido-6-{[(2R,3R,4R,5S)-3-{[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl …
Matched Products: … STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial ... STREPTOMYCIN SULFAT ENJEKTABL FLAKON, 1 ADET ... KRİSTALİZE STREPTOMİSİN SÜLFAT 1 G ENJEKSİYONLUK ÇÖZELTİ TOZU, 50 ADET …
Matched Products: … STREPTOMYCIN SULFATE FOR INJECTION 1 g/vial ... STREPTOMYCIN SULFAT ENJEKTABL FLAKON, 1 ADET ... KRİSTALİZE STREPTOMİSİN SÜLFAT 1 G ENJEKSİYONLUK ÇÖZELTİ TOZU, 50 ADET …
Displaying drugs 1851 - 1875 of 7740 in total