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Displaying drugs 176 - 200 of 3077 in total

Zenocutuzumab

Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Cefotetan

A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Approved
Matched Synonyms: … -(((1-methyl-1H-tetrazol-5- yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2- carboxylic acid …
Matched Iupac: … methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Description: … of both aerobic and anaerobic gram-positive and gram-negative microorganisms. ... The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range …
Matched Products: … Cefotetan and Dextrose …

Delolimogene mupadenorepvec

Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …

Cotsiranib

Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …

PEP0101

PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …

Padimate O

Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in concentrations up to 8%, as regulated by the FDA . It is a structurally-related compound to DB02362 that absorbs UV-B rays to prevent photodamage. It penetrates human skin, and is shown to induce non-ligatable strand...
Approved
Matched Description: … It penetrates human skin, and is shown to induce non-ligatable strand breaks on DNA _in vitro_ and mutagenic ... Padimate O is an active sunscreen agent in cosmetics and over-the-counter sunscreen drug products in …
Matched Mixtures name: … Sun and Ski Stick SPF 15 ... Phineas and Ferb Sun Smacker SPF 24 Berry Busted ... Aruba Aloe Lip Sunscreen and Moisturizer …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Products: … Hand and Body Lotion SPF 15 ... Green Tea and Ginkgo Moisturizer SPF 10 …

Capsicum oleoresin

Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers. When the plants are finely ground, capsicum oleoresin is formed after the extraction process of capsaicin using oragnic solvents such as ethanol. It is commonly used as a culinary...
Approved
Matched Description: … pains of muscles and joints as an active ingredient in topical OTC preparations and has been studied ... , nordihydrocapsaicin, homocapsaicin, and homodihydrocapsaicin [A32318]. ... [DB06774] and dihydrocapsaicin are the most pungent capsaicinoid analogues [A32318]. …
Matched Mixtures name: … Half and Half Balm ... Hot Spice and Ice …
Matched Products: … Sheffield Arthritis and Muscle Pain Relief …

Diphenhydramine

Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and stings, and rashes [L5263, L5266, L5269, F3379]. However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269,...
Approved
Investigational
Matched Description: … stings, and rashes [L5263, L5266, L5269, F3379]. ... receptor antihistamine that is used extensively for the treatment of seasonal allergies, insect bites and ... However, it also has antiemetic, antitussive, hypnotic, and antiparkinson properties [L5269, F3352]. …
Matched Mixtures name: … Naproxen Sodium and Diphenhydramine Hydrochloride ... Naproxen Sodium Diphenhydramine Hydrochloride ... Ibuprofen and Diphenhydramine Citrate …
Matched Salts name: … Diphenhydramine citrate ... Diphenhydramine hydrochloride …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Hypnotics and Sedatives ... naproxen and diphenhydramine ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Up and Up Allergy Relief ... Up and Up Nighttime Sleep-aid ... Berkley and Jensen Allergy …

Oxymetazoline

Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with ... affinity to both α1- and α2-adrenoceptors. ... is used for regional anesthesia during dental procedures in children and adults. …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Salts name: … Oxymetazoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … Up and Up nasal ... Up and up nasal ... Breaze Nasal Sinus Colds and Allergies …

Pacanalotamab

Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and …

Talquetamab

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Posoleucel

Investigational
Matched Synonyms: … specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and …

Camphor

Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often ... The FDA ruled that camphorated oil could not be marketed in the United States and that no product could …
Matched Mixtures name: … MHS Wong Family Iron Palm Jow ... Dermoplex Bite and Sting Cream ... Jack and Jill Rub …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics …
Matched Products: … Muscle and Joint HRX Pain Relieving ... Joints and Muscles Pain Relieving ... Earths Care Muscle and Joint Rub …

Dimethicone

Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties. Dimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. It is used in a number of health and beauty products including hair care...
Approved
Matched Description: … for children and may serve as less toxic and less resistance-prone alternative to pesticide-containing ... , leave-in conditioner, and de-tangling products. ... surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and …
Matched Mixtures name: … Loperamide Hydrochloride and Simethicone ... Loperamide Hydrochloride and Simethicone ... Loperamide Hydrochloride and Simethicone …
Matched Categories: … Basic Ointments and Protectants ... Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides ... Skin and Mucous Membrane Agents ... Scabicides, Insecticides and Repellents …
Matched Products: … Mi-Acid Gas Relief ... Hyaluronic Acid Collagen Essence Mask ... Super Serum Anti Aging and Firming …

gamma-Aminobutyric acid

The most common inhibitory neurotransmitter in the central nervous system.
Approved
Investigational
Matched Synonyms: … piperidic acid ... piperidinic acid ... 4-aminobutanoic acid …
Matched Name: … gamma-Aminobutyric acid …
Matched Iupac: … 4-aminobutanoic acid …
Matched Salts name: … Gamma-Aminobutyric Acid Hydrochloride …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids …
Matched Products: … Gongjinhyang Qi and Jin Eye …

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase

Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational lentiviral gene therapy. It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically modified ex vivo with EFS-ADA LV.
Investigational
Matched Name: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase …
Matched Description: … Autologous CD34+ hematopoietic stem and progenitor cells expressing adenosine deaminase is an investigational ... It comprises autologous CD34+ hematopoietic stem and progenitor cells (HSPCs) that had been genetically …

Pleospora tarda

Pleospora tarda allergenic extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Stemphylium botryosum …

Pine needle oil (pinus mugo)

Pine needle oil is obtained from the needles of Pinus mugo tree via steam distillation. Major components of pine needle oil (pinus mugo) include α-Pinene, β-pinene, δ-3-carene, limonene, β-phellandrene, (E)-caryophyllene, and germacrene D. It is present in aromatherapeutic agents as a massage oil or fragrance and may also be used...
Experimental
Matched Description: … , lubricant, sanitizer, antimicrobial, insecticide and organic herbicide. ... oil (pinus mugo) include α-Pinene, β-pinene, δ-3-carene, limonene, β-phellandrene, (E)-caryophyllene, and ... It is present in aromatherapeutic agents as a massage oil or fragrance and may also be used as a disinfectant …
Matched Categories: … Herbs and Natural Products …
Matched Products: … JEUNCELL Hair Loss Prevention and Hair Growth Tonic …

Ambrosia artemisiifolia pollen

Ambrosia artemisiifolia pollen is the pollen of the Ambrosia artemisiifolia plant. Ambrosia artemisiifolia pollen is mainly used in allergenic testing.
Approved
Matched Mixtures name: … Short and Giant Ragweed Pollen Mix ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia ... Pollens - Weeds and Garden Plants, Ragweed, Mixed Ambrosia …
Matched Products: … Pollens - Weeds and Garden Plants, Short Ragweed, Ambrosia artemisiifolia …

Polyethylene glycol 400

Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain various derivatives and have various functions. Because many PEG types are hydrophilic, they are favorably used as enhancers of penetration, and used heavily in topical dermatological preparations. PEGs, along with their many nonionic derivatives, are...
Approved
Matched Description: … Examples of PEGylated medications are PEG-interferon alpha (Pegintron) and PEG-filgrastim. ... various derivatives and have various functions. ... Polyethylene glycols (PEGs) are products made of condensed ethylene oxide and water that can contain …
Matched Mixtures name: … Redness reliever and Lubricant ... Systane Day and Night Value Pack ... Systane Day and Night Value Pack …
Matched Products: … Foster and Thrive Dry Eye Relief …

Artemisia vulgaris pollen

Artemisia vulgaris pollen is the pollen of the Artemisia vulgaris plant. Artemisia vulgaris pollen is mainly used in allergenic testing.
Approved
Matched Products: … Pollens - Weeds and Garden Plants, Sagebrush, Mugwort Artemisia vulgaris …

Suratadenoturev

Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …

Zinc oxide

Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes. It occurs naturally as the mineral zincite, but most zinc oxide is produced...
Approved
Matched Description: … lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and ... It is also widely used to treat a variety of other skin conditions, in products such as baby powder and ... barrier creams to treat diaper rashes, calamine cream, anti-dandruff shampoos, and antiseptic ointments …
Matched Mixtures name: … PNV Ferrous Fumarate Docusate Folic Acid ... Iron Polysaccharides Folic Acid DHA ... Mineral Oil, Pramoxine Hydrochloride and Zinc Oxide …
Matched Categories: … Basic Ointments and Protectants ... Basic Powders and Demulcents ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Oars and Alps SPF 50 Mineral ... Oars and Alps SPF 30 100% Mineral Sunscreen ... Oars and Alps 100% Mineral Antioxidant Sunscreen …

Cefoxitin

Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Synonyms: … methyl]-7-methoxy-8-oxo-7-[(thiophen-2-enyl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Iupac: … methyl]-7-methoxy-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid …
Matched Salts name: … Cefoxitin sodium …
Matched Products: … Cefoxitin and Dextrose …

Epicoccum nigrum

Epicoccum nigrum is a fungus which can provoke allergic reactions. Epicoccum nigrum extract is used in allergenic testing.
Approved
Matched Products: … Molds, Rusts and Smuts, Epicoccum nigrum …
Displaying drugs 176 - 200 of 3077 in total