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Displaying drugs 176 - 200 of 708 in total
Lamivudine
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
Approved
Investigational
Matched Synonyms: … (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine and abacavir ... stavudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …
Matched Iupac: … 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one …
Matched Description: … It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). ... A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon …
Matched Mixtures name: … Lamivudine and Zidovudine ... Lamivudine and Zidovudine ... Lamivudine and Zidovudine …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor ... lamivudine and abacavir ... stavudine and lamivudine …
Matched Products: … Lamivudine and Zidovudine …
Piperonyl butoxide
Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist. It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as...
Approved
Vet approved
Matched Description: … It is used for the treatment of head, pubic (crab), and body lice. ... its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Mixtures name: … Medi and Lice Lice Killing ... Lice-Nil Lice and Eggs Killer ... Weeks and Leo Complete Lice Treatment …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Reserpine
An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Iupac: … -(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4( …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Matched Description: … The FDA withdrew its approval for the use of all oral dosage form drug products containing more than 1 ... serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …
Mirtazapine
Mirtazapine is a tetracyclic piperazino-azepine antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. This drug was first manufactured by Organon Inc., and received FDA approval in 1997 for the treatment of major depressive disorder.[T595, L6157] The effects of this...
Approved
Matched Iupac: … 5-methyl-2,5,19-triazatetracyclo[13.4.0.0^{2,7}.0^{8,13}]nonadeca-1(15),8,10,12,16,18-hexaene …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. ... prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. …
Matched Description: … [T595, L6157] The effects of this drug may be observed as early as 1 week after beginning therapy. ... prevent nausea and vomiting after surgery. ... ., and received FDA approval in 1997 for the treatment of major depressive disorder. …
Repotrectinib
Repotrectinib is a next-generation tyrosine kinase inhibitor (TKI) specifically designed to address resistance in the treatment of non-small cell lung cancer (NSCLC), specifically due to mutations in the ROS1 gene. ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation ROS1 G2032R is responsible for...
Approved
Investigational
Matched Synonyms: … (3R,6S,)-45-FLUORO-3,6-DIMETHYL-5-OXA-2,8-DIAZA-1(5,3)-PYRAZOLO(1,5-A)PYRIMIDINA-4(1,2)-BENZENANONAPHAN ... Fluoro-7,13-Dimethyl-6,7,13,14-Tetrahydro-1,15-Ethenopyrazolo[4,3-F][1,4,8,10]Benzoxatriazacyclotridecin-4( ... 1,15-ETHENO-1H-PYRAZOLO(4,3-F)(1,4,8,10)BENZOXATRIAZACYCLOTRIDECIN-4(5H)-ONE, 11-FLUORO-6,7,13,14-TETRAHYDRO …
Matched Iupac: … 11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa-1( …
Matched Description: … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate ... was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively. ... [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 11S)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazatetracyclo[13.5.2.0^{4,9}.0^{18,22}]docosa-1( …
Matched Description: … This approval is based on favorable results from the TRIDENT-1 study, where the objective response rate ... was 79% in TKI-naive patients and 38% in TKI-pretreated patients respectively. ... [A262056] ROS1 mutations are one of the defined oncogenic drives of NSCLC, and the solvent-front mutation …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Brentuximab vedotin
Brentuximab vedotin, also known as Adcetris®, is an antibody-drug conjugate that combines an anti-CD30 antibody with the drug monomethyl auristatin E (MMAE). It is an anti-neoplastic agent used in the treatment of Hodgkin's lymphoma and systemic anaplastic large-cell lymphoma. Brentuximab vedotin was initially approved in 2011. In January 2012, the...
Approved
Investigational
Matched Description: … [L1737]
The ECHELON-1 study results demonstrated superior efficacy of the drug combined with a chemotherapy ... Lymphoma may begin anywhere in the body and can spread to nearby lymph nodes. ... Food and Drug Administration approved Adcetris in March 2018 to treat adult patients with previously …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …
Matched Products: … ADCETRIS 50 MG IV INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇIN TOZ IÇEREN FLAKON ,FLAKON, 1 ADET …
Pixantrone
Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. It is similar in structure to anthracyclines such as mitoxantrone, but exerts fewer toxic effects on cardiac tissue. [2] The lower cardio-toxic effects of pixantrone may be explained, in part, by its redox inactivity [3]. Pixantrone does not bind...
Approved
Investigational
Matched Description: … It also inhibits doxorubicinol formation in human myocardium. [3] As a result, it is believed to be less ... Pixantrone is an aza-anthracenedione and DNA intercalator which inhibits topoisomerase II. ... Pixantrone does not bind iron and promotes the formation of reactive oxygen species to a lesser degree …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Palonosetron
Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that appear more than 24 hours after the first...
Approved
Investigational
Matched Synonyms: … 2-(1-Azabicyclo(2.2.2)oct-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benz(de)isoquinolin-1-one ... (3aS)-2-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinolin-1-one …
Matched Iupac: … (5S)-3-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3-azatricyclo[7.3.1.0⁵,¹³]trideca-1(12),9(13),10-trien-2- …
Matched Description: … Food and Drug Administration. ... treatment of chemotherapy-induced nausea and vomiting (CINV). ... It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … IÇEREN FLAKON, 1 ADET ... ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET ... ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET …
Matched Iupac: … (5S)-3-[(3S)-1-azabicyclo[2.2.2]octan-3-yl]-3-azatricyclo[7.3.1.0⁵,¹³]trideca-1(12),9(13),10-trien-2- …
Matched Description: … Food and Drug Administration. ... treatment of chemotherapy-induced nausea and vomiting (CINV). ... It is the most effective of the 5-HT3 antagonists in controlling delayed CINV nausea and vomiting that …
Matched Categories: … Alimentary Tract and Metabolism ... Antiemetics and Antinauseants …
Matched Products: … IÇEREN FLAKON, 1 ADET ... ENJEKSIYONLUK ÇÖZELTI IÇEREN FLAKON, 1 ADET ... ENJEKSIYONLUK COZELTI ICEREN FLAKON, 1 ADET …
Perfluorohexyloctane
Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight hydrogenated carbon atoms. It is an inert, slightly amphiphilic compound. Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative.[A259746, A259751]
Perfluorohexyloctane...
Approved
Matched Synonyms: … 1-(perfluorohexyl)octane …
Matched Description: … Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight …
Matched Categories: … Ophthalmological and Otological Preparations …
Matched Description: … Perfluorohexyloctane is a semifluorinated alkane that contains six perfluorinated carbon atoms and eight …
Matched Categories: … Ophthalmological and Otological Preparations …
Pilocarpine
A naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist.[A262016, A262036] Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by...
Approved
Investigational
Matched Synonyms: … 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)- …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Description: … intraocular pressure and glaucoma. ... [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Salts cas: … 148-72-1 …
Matched Mixtures name: … E-pilo-1 Oph Soln ... E-pilo 1 Ophthalmic Solution ... Timpilo 4 …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … -carpine 1% ... PILOMANN 1% ... Pilocarpine 1% …
Matched Iupac: … (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one …
Matched Description: … intraocular pressure and glaucoma. ... [A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated …
Matched Salts cas: … 148-72-1 …
Matched Mixtures name: … E-pilo-1 Oph Soln ... E-pilo 1 Ophthalmic Solution ... Timpilo 4 …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Matched Products: … -carpine 1% ... PILOMANN 1% ... Pilocarpine 1% …
Xylometazoline
Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Iupac: … 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Mixtures name: … NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Otrivin plus Dexpanthenol 1 mg/ml + 50 mg/ml Nasenspray, Lösung ... NASOVİNE DUO 0,5 MG + 0,6 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … 4 Way Moisturizing Relief ... Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops …
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Mixtures name: … NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... Otrivin plus Dexpanthenol 1 mg/ml + 50 mg/ml Nasenspray, Lösung ... NASOVİNE DUO 0,5 MG + 0,6 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … 4 Way Moisturizing Relief ... Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops …
Malathion
Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.
Approved
Investigational
Matched Description: … Malathion is an irreversible cholinesterase inhibitor and has low human toxicity. …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … A-FLEAZ SHAMPOO 1% w/w …
Matched Categories: … Scabicides, Insecticides and Repellents ... Antiparasitic Products, Insecticides and Repellents …
Matched Products: … A-FLEAZ SHAMPOO 1% w/w …
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Mixtures name: … AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET ... DESMONT 2.5 MG/4 MG ÇİĞNEME TABLETİ, 30 ADET …
Matched Categories: … Loratadine and derivatives ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Description: … Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral ... Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter …
Matched Mixtures name: … AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET ... DESMONT 2.5 MG/4 MG ÇİĞNEME TABLETİ, 30 ADET …
Matched Categories: … Loratadine and derivatives ... Heterocyclic Compounds, 1-Ring …
Docosanol
Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV). Docosanol inhibits fusion between the plasma membrane and the herpes...
Approved
Investigational
Matched Synonyms: … 1-Docosanol ... Docosan-1-ol …
Matched Iupac: … docosan-1-ol …
Matched Description: … preventing viral entry into cells and subsequent viral replication. ... Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby …
Matched Iupac: … docosan-1-ol …
Matched Description: … preventing viral entry into cells and subsequent viral replication. ... Docosanol inhibits fusion between the plasma membrane and the herpes simplex virus (HSV) envelope, thereby …
Lapatinib
Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer. It was approved by the FDA on March 13, 2007, for use in patients with advanced metastatic breast cancer in conjunction with the chemotherapy drug capecitabine. Lapatinib is a...
Approved
Investigational
Matched Synonyms: … )-4-quinazolinamine ... N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl …
Matched Iupac: … )quinazolin-4-amine ... N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl …
Matched Description: … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor ... anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors …
Matched Iupac: … )quinazolin-4-amine ... N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl …
Matched Description: … Lapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor ... anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitors …
Dequalinium
Dequalinium is an antibacterial agent with multi-targeted actions. It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. It is a quaternary ammonium compound, as it consists of an amphipathic cation with two aminoquinaldinium rings at both ends of a long hydrophobic hydrocarbon chain. Due to its flexible structure, dequalinium...
Approved
Investigational
Matched Synonyms: … Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-Decamethylenebis(4-aminoquinaldinium chloride) ... 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …
Matched Description: … various OTC products to treat conditions of oral infections and inflammation. ... It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. ... Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. …
Matched Mixtures name: … Eucillin "B" - Salbe …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Matched Iupac: … 4-amino-1-[10-(4-amino-2-methylquinolin-1-ium-1-yl)decyl]-2-methylquinolin-1-ium …
Matched Description: … various OTC products to treat conditions of oral infections and inflammation. ... It also possesses antifungal, antiparasitic, antiviral, anticancer, and neuroprotective properties. ... Due to its flexible structure, dequalinium was investigated to build drug and gene delivery systems. …
Matched Mixtures name: … Eucillin "B" - Salbe …
Matched Categories: … Antiseptics and Disinfectants ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …
Betrixaban
Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa . It was selected among all lead compounds due to its low hERG channel affinity while sustaining its factor Xa inhibition capacity . Betrixaban, now developed by Portola Pharmaceuticals...
Approved
Investigational
Matched Synonyms: … N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide ... N-(5-chloropyridin-2-yl)-2-[[4-(N,N-dimethylcarbamimidoyl)benzoyl]amino]-5-methoxybenzamide …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-(5-chloropyridin-2-yl)-2-[4-(N,N-dimethylcarbamimidoyl)benzamido]-5-methoxybenzamide …
Matched Description: … Betrixaban is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible ... VTE can be manifested as deep vein thrombosis or pulmonary embolism and it is a leading cause of preventable …
Matched Categories: … Blood and Blood Forming Organs ... Heterocyclic Compounds, 1-Ring …
Mitoxantrone
An anthracenedione-derived antineoplastic agent.
Approved
Investigational
Matched Categories: … Anthracyclines and Related Substances ... Antineoplastic and Immunomodulating Agents ... Cytotoxic Antibiotics and Related Substances …
Matched Products: … MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MİTOXANTRONE-KOÇAK 20 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MİTOXANTRON EBEWE 10 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Matched Products: … MİTOXANTRONE BAXTER 20 MG/10 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... MİTOXANTRONE-KOÇAK 20 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... MİTOXANTRON EBEWE 10 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Belatacept
Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it...
Approved
Investigational
Matched Description: … antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin ... Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and ... Belatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Delavirdine
A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1.
Approved
Matched Synonyms: … (N-[2-[4-[3-(1-methylethylamino)pyridin-2-yl]piperazin-1-yl]carbonyl-1H-indol-5-yl] methanesulfonamide ... 2-(4-(5-methanesulfonamido-1H-indol-2-ylcarbonyl)-1-piperazinyl)-N-(1-methylethyl)-3-pyridinamine ... 1-(3-((1-methylethyl)amino)-2-pyridinyl)-4-((5-((methylsulfonyl)amino)-1H-indol-2-yl)carbonyl)piperazine …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Description: … A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[2-(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazine-1-carbonyl)-1H-indol-5-yl]methanesulfonamide …
Matched Description: … A potent, non-nucleoside reverse transcriptase inhibitor with activity specific for HIV-1. …
Matched Categories: … Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor ... Heterocyclic Compounds, 1-Ring …
Abiraterone
Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Iupac: … (3aS,3bR,7S,9aR,9bS,11aS)-9a,11a-dimethyl-1-(pyridin-3-yl)-3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H, …
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... [L40968, L40193, L47740, L47745] As abiraterone has poor oral bioavailability and is susceptible to …
Matched Categories: … niraparib and abiraterone ... abiraterone and prednisolone ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... [L40968, L40193, L47740, L47745] As abiraterone has poor oral bioavailability and is susceptible to …
Matched Categories: … niraparib and abiraterone ... abiraterone and prednisolone ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …
Binimetinib
Binimetinib, also known as Mektovi, is a potent and selective oral mitogen-activated protein kinase 1/2 (MEK 1/2) inhibitor which is combined with Encorafenib.[A34275,L3335]
On June 27, 2018, the Food and Drug Administration approved the combination of Encorafenib and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients...
Approved
Investigational
Matched Iupac: … 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-1,3-benzodiazole-6-carboxamide …
Matched Description: … 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib]. ... ] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with ... Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MAP Kinase Kinase 1, antagonists & inhibitors …
Matched Description: … 1/2 (MEK 1/2) inhibitor which is combined with [Encorafenib]. ... ] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients with ... Binimetinib, also known as _Mektovi_, is a potent and selective oral mitogen-activated protein kinase …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... MAP Kinase Kinase 1, antagonists & inhibitors …
Dosulepin
Dosulepin (INN, BAN) formerly known as dothiepin (USAN), is a tricyclic antidepressant with anxiolytic properties that is used in several European and South Asian countries, as well as Australia, South Africa, and New Zealand. It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. Dosulepin inhibits...
Approved
Matched Synonyms: … (3E)-3-dibenzo[b,e]thiepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine ... 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzo(b,e)thiepin …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … South Asian countries, as well as Australia, South Africa, and New Zealand. ... anticholinergic, antihistamine and central sedative properties [L882]. ... It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. …
Matched Salts cas: … 897-15-4 …
Matched Iupac: … dimethyl({3-[(2E)-9-thiatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-ylidene]propyl})amine …
Matched Description: … South Asian countries, as well as Australia, South Africa, and New Zealand. ... anticholinergic, antihistamine and central sedative properties [L882]. ... It is not FDA-approved due to low therpeutic index and significant toxicity in overdose. …
Matched Salts cas: … 897-15-4 …
Bedaquiline
Bedaquiline is a bactericidal antimycobacterial drug belonging to the class of diarylquinoline. The quinolinic central heterocyclic nucleus with alcohol and amine side chains is responsible for bedaquiline-mediated antimycobacterial activity. Although it is closely related to fluoroquinolones, bedaquiline does not affect DNA gyrase; instead, bedaquiline inhibits the c subunit of ATP...
Approved
Matched Synonyms: … 1-(6-Bromo-2-methoxy-quinolin-3-yl)-4-dimethylamino-2-naphthalen-1-yl-1-phenyl-butan-2-ol …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and ... [A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate ... December 28, 2012, to treat pulmonary MDR-TB, following favorable results in multiple pre-clinical and …
Matched Iupac: … (1R,2S)-1-(6-bromo-2-methoxyquinolin-3-yl)-4-(dimethylamino)-2-(naphthalen-1-yl)-1-phenylbutan-2-ol …
Matched Description: … [rifampin], is highly effective, the emergence of multidrug-resistant TB (MDR-TB) to [isoniazid] and ... [A261856] Currently, bedaquiline is the last-line anti-TB drug and must only be used in an appropriate ... December 28, 2012, to treat pulmonary MDR-TB, following favorable results in multiple pre-clinical and …
Acetaminophen
Acetaminophen (paracetamol), also commonly known as Tylenol, is the most commonly taken analgesic worldwide and is recommended as first-line therapy in pain conditions by the World Health Organization (WHO). It is also used for its antipyretic effects, helping to reduce fever. This drug was initially approved by the U.S. FDA...
Approved
Matched Synonyms: … 4-acetamidophenol ... 4-(Acetylamino)phenol ... 4'-hydroxyacetanilide …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Description: … of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and …
Matched Mixtures name: … Adventure Medical Kits 1-4 Person First Aid ... DAYFLU B ... MYOGESIC-B …
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … VOLPAN TABLET, 4 ADET ... VOLPAN KOMPOZE TABLET, 4 ADET ... PARACETAMOLO B. BRAUN …
Matched Iupac: … N-(4-hydroxyphenyl)acetamide …
Matched Description: … of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines ... tablets, injection, suppository, and other forms. ... Acetaminophen (paracetamol), also commonly known as _Tylenol_, is the most commonly taken analgesic worldwide and …
Matched Mixtures name: … Adventure Medical Kits 1-4 Person First Aid ... DAYFLU B ... MYOGESIC-B …
Matched Categories: … Acetaminophen and Prodrugs ... codeine and paracetamol ... tramadol and paracetamol ... oxycodone and paracetamol ... hydrocodone and paracetamol …
Matched Products: … VOLPAN TABLET, 4 ADET ... VOLPAN KOMPOZE TABLET, 4 ADET ... PARACETAMOLO B. BRAUN …
Displaying drugs 176 - 200 of 708 in total