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Displaying drugs 176 - 200 of 14647 in total

Isometheptene

Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Approved
Matched Description: … It is used for treating migraines and tension headaches. …
Matched Mixtures name: … Isometheptene Mucate, Caffeine, and Acetaminophen ... Isometheptene Mucate, Caffeine, and Acetaminophen ... Isometheptene Mucate, Caffeine, and Acetaminophen …
Matched Categories: … Alimentary Tract and Metabolism ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …

Progesterone

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prevent ovulation...
Approved
Vet approved
Matched Description: … Please see [Medroxyprogesterone acetate], [Megestrol acetate], [Dydrogesterone] and [Hydroxyprogesterone ... , embryo implantation, and the successful establishment of pregnancy. ... ], [A175612] as well as in other formulations to promote and support pregnancy. …
Matched Mixtures name: … Estradiol and Progesterone …
Matched Categories: … progesterone and estrogen ... Progesterone and Derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Tapentadol

Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596] Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved

Cholesterol

The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Approved
Investigational
Matched Description: … cord, and in animal fats and oils. ... The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal …

Potassium chloride

A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Description: … in fertilizers and explosives. ... that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and ... crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and …
Matched Mixtures name: … HARTMANN ALPHA ... ACETATE RINGER'S INJECTION ... Acetate Concentrate R07376 …
Matched Categories: … Alimentary Tract and Metabolism ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Apraclonidine

Apraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Approved
Matched Categories: … Antiglaucoma Preparations and Miotics ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists …

Ergosterol

A steroid of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and because when it is present in SKIN of animals, ULTRAVIOLET RAYS break a bond to result in ERGOCALCIFEROL.
Approved
Experimental
Matched Description: … of interest both because its biosynthesis in FUNGI is a target of ANTIFUNGAL AGENTS, notably AZOLES, and …
Matched Categories: … Diet, Food, and Nutrition …

Cimetidine

A histamine congener, it competitively inhibits histamine binding to histamine H2 receptors. Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output. It also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Approved
Investigational
Matched Description: … It inhibits gastric acid secretion, as well as pepsin and gastrins output. …
Matched Categories: … Alimentary Tract and Metabolism ... Metabolic Side Effects of Drugs and Substances ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Acid Reducer …

Interferon alfa-n3

Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched Description: … including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). ... Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms …
Matched Categories: … Interferon alpha ... Interferon-alpha ... Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …

Hydroxocobalamin

Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.
Approved
Matched International brands: … Alpha-Redisol …
Matched Description: … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. ... Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B …
Matched Salts name: … Hydroxocobalamin acetate …
Matched Categories: … Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid …

Acetic acid

Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or...
Approved
Matched Description: … It is used locally, occasionally internally, as a counterirritant and also as a reagent. ... Acetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. …
Matched Mixtures name: … Acetate Buffer Ph 4.85 ... Hydrocortisone and Acetic Acid ... Hydrocortisone and Acetic Acid …
Matched Categories: … Indicators and Reagents ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Acetohydroxamic acid

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics...
Approved
Matched Description: … Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure ... Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. …
Matched Categories: … Genito Urinary System and Sex Hormones …

Oxycodone

Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Description: … [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as …
Matched Mixtures name: … Oxycodone and Aspirin ... Oxycodone and Aspirin ... Oxycodone and Acetaminophen …
Matched Categories: … oxycodone and naloxone ... oxycodone and ibuprofen ... oxycodone and naltrexone ... oxycodone and paracetamol ... oxycodone and acetylsalicylic acid …

Norepinephrine

Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Alpha-and Beta-adrenergic Agonists ... Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Adrenergic alpha-Agonists ... Adrenergic alpha-1 Receptor Agonists …

Salmeterol

Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD.[L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, salbutamol. Salmeterol was first described in the literature in 1988. Salmeterol's structure...
Approved
Matched Description: … long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and …
Matched Mixtures name: … Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol ... Fluticasone Propionate and Salmeterol …
Matched Categories: … salmeterol and budesonide ... salmeterol and fluticasone …

Tolazoline

A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Approved
Vet approved
Matched Description: … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. ... Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the …
Matched Categories: … Topical Products for Joint and Muscular Pain ... Adrenergic alpha-Antagonists ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …

Icodextrin

Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stage renal disease. It is injected as a solution into the peritoneal cavity. The drug is absorbed via convective transport...
Approved
Investigational
Matched Description: … It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal …

Beremagene geperpavec

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …

Hydroxyethyl cellulose

Hydroxyethyl cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and stabilizing properties. It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its non-ionic and water-soluble nature. It is often used as an ingredient in ophthalmic pharmaceutical preparations such as...
Approved
Matched Description: … non-ionic and water-soluble nature. ... It is used as a key ingredient in many household cleaning products, lubricants and cosmetics due to its ... cellulose is a polysaccharide derivative with gel thickening, emulsifying, bubble-forming, water-retaining and …

Dostarlimab

Dostarlimab is an IgG4 humanized monoclonal antibody targeted against the human programmed death receptor-1 (PD-1). PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - some cancers leverage this system by overexpressing PD-1 ligands, thereby effectively inhibiting the anti-tumor immune response that would typically attempt...
Approved
Investigational
Matched Description: … those of the skin, lung, kidneys, and liver. ... [L33320] PD-1 receptors are found on T-cells and, when activated, serve to inhibit immune responses - ... [A234379] Agents acting on the PD-1 pathway, such as [nivolumab] and [pembrolizumab], facilitate endogenous …
Matched Categories: … Hydrogen Sulfide ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Description: … drug whose main use is after organ transplant to reduce the activity of the patient's immune system and ... the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and ... This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL …
Matched Categories: … Skin and Mucous Membrane Agents ... Antineoplastic and Immunomodulating Agents …

Droxidopa

Droxidopa is a precursor of noradrenaline that is used in the treatment of Parkinsonism. It is approved for use in Japan and is currently in trials in the U.S. The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated in the treatment of orthostatic hypotension. There is a...
Approved
Investigational
Matched Description: … associated with Parkinson's disease , pure autonomic failure, and multiple system atrophy, and is the ... It is approved for use in Japan and is currently in trials in the U.S. ... The racaemic form (dl-threo-3,4-dihydroxyphenylserine) has also been used, and has been investigated …
Matched Categories: … Adrenergic alpha-Agonists ... Epinephrine and similars ... Adrenergic alpha-1 Receptor Agonists ... Adrenergic and Dopaminergic Agents ... Adrenergic alpha-2 Receptor Agonists …

Carglumic acid

Carglumic acid is a drug used for the treatment of hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. This rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. Carglumic acid was...
Approved
Matched Description: … Food and Drug Administration (FDA) on 18 March 2010. ... cause neurologic problems, cerebral edema, coma, and death. ... disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Dichloroacetic acid

Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen atoms of the methyl group have been replaced by chlorine atoms. Salts of DCA are used as drugs since they inhibit the enzyme pyruvate dehydrogenase kinase. Early reports of its activity...
Approved
Investigational
Matched Description: … Dichloroacetic acid, often abbreviated DCA, is an acid analogue of acetic acid in which two of the three hydrogen ... and removal of a wide variety of skin and tissue lesions), but was cancelled post market. ... DCA was approved for use in Canada in 1989 (as a topical formulation for treatment of warts and for cauterization …

L-Lactic acid

Approved
Experimental
Displaying drugs 176 - 200 of 14647 in total