Displaying drugs 2076 - 2100 of 2904 in total
Celastrol
Celastrol is a pentacyclic triterpenoid isolated from the root extracts of Tripterygium wilfordii.
Investigational
Matched Synonyms: … 24-nor-d:a-friedooleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-2-oxo- ... 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid, 3-hydroxy-9,13-dimethyl-2-oxo-, (9.beta.,13.alpha …
Matched Iupac: … 9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid …
Matched Description: … Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_. …
Matched Iupac: … 9,12b,14a-hexamethyl-11-oxo-1,2,3,4,4a,5,6,6a,11,12b,13,14,14a,14b-tetradecahydropicene-2-carboxylic acid …
Matched Description: … Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_. …
Des(carbamimidoyl) zanamivir
Experimental
Matched Synonyms: … 4-Amino-2-deoxy-2,3-dehydro-N-neuraminic acid …
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Matched Iupac: … (2R,3R,4S)-4-amino-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid …
Naproxcinod
Investigational
Matched Synonyms: … (S)-2-(6-Methoxy-2-naphthyl)propanoic acid 4-nitrooxybutyl ester …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Naphthaleneacetic Acids …
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Naphthaleneacetic Acids …
Ethyl salicylate
Approved
Experimental
Matched Synonyms: … Salicyclic acid, ethyl ester …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
Matched Categories: … Hydroxy Acids ... Acids, Carbocyclic ... Carboxylic Acids …
PIK-75
PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.
Investigational
Matched Synonyms: … Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide …
APD-209
Investigational
Matched Synonyms: … -neuraminic acid, n-acetyl-2-o-(7,26-dioxo-10,13,16,19,22-pentaoxa-6,25-diazapentaconta-35,37-diyn-1- …
Sovesudil
Investigational
Matched Synonyms: … (1,1'-biphenyl)-3-carboxylic acid, 2'-(aminomethyl)-5'-(((3-fluoro-4-pyridinyl)amino)carbonyl)-, propyl …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids …
Propagermanium
Investigational
Matched Synonyms: … 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid ... Propanoic acid, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)bis- …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Bis(2,2-dimethylpropanoyloxymethyl) VK-0214
Investigational
Matched Synonyms: … 2,2-dimethylpropanoic acid 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy) ... Propanoic acid, 2,2-dimethyl-, 1,1'-((((4-((4-hydroxy-3-(phenylmethyl)phenyl)methyl)-3,5-dimethylphenoxy …
Dimenhydrinate
Dimehydrinate was first described in the literature in 1949, and patented in 1950. Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and...
Approved
Matched Description: … Dimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. ... ] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. ... B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and …
Matched Products: … MAREOL® TABLETAS …
Matched Products: … MAREOL® TABLETAS …
Iptacopan
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and ... the glycosyl phosphatidylinositol–anchored proteins that normally anchor 2 membrane proteins, CD55 and ... benefit of targeting factor B, which only affect the alternative complement pathway, leaving the classic and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Urethane
Urethane, formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and was removed from the Canadian, US, and UK markets in 1963.
Approved
Withdrawn
Matched Synonyms: … Carbamic acid ethyl ester …
Matched Description: … was removed from the Canadian, US, and UK markets in 1963. ... formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Description: … was removed from the Canadian, US, and UK markets in 1963. ... formerly marketed as an inactive ingredient in Profenil injection, was determined to be carcinogenic and …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
APT-101
Investigational
Matched Synonyms: … Cyclopentyl-5-(2-(trifluoromethyl)phenyl)-1H-pyrazole-3-carboxamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Matched Iupac: … cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Matched Iupac: … cyclopentyl-5-[2-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}formamido)-5-(3,3-difluoropiperidin-1-yl)pentanoic acid …
Ritivixibat
Investigational
Matched Synonyms: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-1Lambda6,2,5-benzothiadiazepin-8-yl]oxy)propanoic acid …
Matched Iupac: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin-8-yl]oxy}propanoic acid …
Matched Iupac: … methylsulfanyl)-1,1-dioxo-5-phenyl-2,3,4,5-tetrahydro-1lambda6,2,5-benzothiadiazepin-8-yl]oxy}propanoic acid …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Synonyms: … 5-Allyl-5-(3-hexyn-2-yl)-1-methylbarbituric acid ... (±)-5-allyl-1-methyl-5-(1-methyl-2-pentynyl)barbituric acid ... α-DL-1-methyl-5-allyl-5-(1'-methylpentyn-2-yl)barbituric acid …
Matched Categories: … Hypnotics and Sedatives …
Matched Categories: … Hypnotics and Sedatives …
Esuberaprost
Investigational
Matched Synonyms: … Aps-314d free acid ... 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4- ... hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid …
Matched Iupac: … hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid …
Matched Iupac: … hydroxy-4-methyloct-1-en-6-yn-1-yl]-7-oxatricyclo[6.4.0.0^{2,6}]dodeca-1(12),8,10-trien-9-yl]butanoic acid …
Rosoxacin
Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with...
Approved
Investigational
Matched Synonyms: … 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and ... Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered …
Matched Iupac: … 1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and ... Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered …
Rugonersen
Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of Angelman Syndrome.
Investigational
Matched Synonyms: … UBE3A antisense oligonucleotide with locked nucleic acids …
Matched Description: … Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of …
Matched Description: … Rugonersen is a locked nucleic acid antisense oligonucleotide under investigation for the treatment of …
Pagibaximab
Investigational
Matched Synonyms: … IMMUNOGLOBULIN G1, ANTI (STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID) (HUMAN MOUSE MONOCLONAL HU96 110 ... Immunoglobulin G1, anti-(Staphylococcus epidermidis lipoteichoic acid) (human-mouse monoclonal heavy ... IMMUNOGLOBULIN G1, ANTI-(STAPHYLOCOCCUS EPIDERMIDIS LIPOTEICHOIC ACID)(HUMAN-MOUSE MONOCLONAL HEAVY CHAIN …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Methylparaben
Methylparaben is used in allergenic testing.
Approved
Matched Synonyms: … p-Hydroxybenzoic acid methyl ester …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Hydroxy Acids …
Ropivacaine
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Synonyms: … L-N-n-propylpipecolic acid-2,6-xylidide …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
AVA-4746
Investigational
Matched Synonyms: … chlorobenzyl)-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3yl)amino)carbonyl)amino-3-(4-methylphenyl)propanoic acid ... Benzenepropanoic acid, .beta.-((((1-((2-chlorophenyl)methyl)-1,2-dihydro-4-hydroxy-5-methyl-2-oxo-3-pyridinyl …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Matched Iupac: … methyl]-4-hydroxy-5-methyl-2-oxo-1,2-dihydropyridin-3-yl}carbamoyl)amino]-3-(4-methylphenyl)propanoic acid …
Clesacostat
Clesacostat is under investigation in clinical trial NCT04321031 (Metabolic Interventions to Resolve Non-alcoholic Steatohepatitis (NASH) With Fibrosis (MIRNA)).
Investigational
Matched Synonyms: … 1-(propan-2-yl)-1,4,6,7-tetrahydrospiro(indazole-5,4'- piperidine)-1'-carbonyl)pyridin-2-yl)benzoic acid ... Benzoic acid, 4-(6-methoxy-4-((1,4,6,7-tetrahydro-1-(1-methylethyl)-7-oxospiro(5h-indazole-5,4'-piperidin …
Displaying drugs 2076 - 2100 of 2904 in total