Displaying drugs 2126 - 2150 of 2788 in total
Tirofiban
Tirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Approved
Matched Synonyms: … (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
Matched Iupac: … (2S)-2-(butane-1-sulfonamido)-3-{4-[4-(piperidin-4-yl)butoxy]phenyl}propanoic acid …
Matched Description: … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Aromatic …
TBI-223
TBI-223 is under investigation in clinical trial NCT06192160 (Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis).
Investigational
Matched Synonyms: … CARBAMIC ACID, N-(((5S)-3-(3-FLUORO-4-(2-OXA-6-AZASPIRO(3.3)HEPT-6-YL)PHENYL)-2-OXO-5-OXAZOLIDINYL)METHYL …
Fibroblast growth factor-1
Investigational
Matched Synonyms: … Acidic fibroblast growth factor ... Fibroblast growth factor, acidic ... Acidic fibroblast growth factor (aFGF) …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Intercellular Signaling Peptides and Proteins …
Ilex paraguariensis leaf
Ilex paraguariensis leaf is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Mate Folium ... Mate Folium (Ilex Paraguariensis St. Hilaire) …
CL-315585
CL-315585 is the D isomer of Verteporfin.
Approved
Matched Synonyms: … 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 ... 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19 …
Aztreonam
A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
Approved
Matched Synonyms: … thiazolyl)(((2S,3S,)-2-methyl-4-oxo-1-sulfo-3-azetidinyl)carbamoyl)methylene)amino)oxy)-2-methylpropionic acid ... {[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-yl]amino} -2- oxoethylidene]amino}oxy)-2-methylpropanoic acid …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Matched Description: … , bladder, and kidneys. ... It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges …
Timolol
Timolol is a nonselective beta-adrenergic antagonist given in an eye drop solution to reduce intraocular pressure, or pressure in the eyes. It is also used in tablet form as a drug to treat hypertension. Timolol was first approved by the FDA in 1978. This drug is marketed by several manufacturers...
Approved
Matched Synonyms: … Timolol anhydrous …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... timolol, thiazides and other diuretics …
Matched Description: … of conditions such as open-angle glaucoma and hypertension. ... [L6724] This drug is marketed by several manufacturers [L6736] and is an effective agent for the management …
Matched Mixtures name: … Dorzolamide Hydrochloride and Timolol Maleate ... Dorzolamide HCl and Timolol Maleate ... Dorzolamide Hydrochloride and Timolol Maleate …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Beta Blocking Agents and Thiazides ... timolol and thiazides ... Beta Blocking Agents, Non-Selective, and Thiazides ... timolol, thiazides and other diuretics …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … Mercaptopurine anhydrous …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Matched Description: … It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Nucleic Acid Synthesis Inhibitors …
Iopamidol
Iopamidol is a contrast agent developed by Bracco with nonionic, low-osmolar properties.
Approved
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids ... Triiodobenzoic Acids …
Matched Products: … IODICA …
Matched Products: … IODICA …
Ertapenem
Ertapenem is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics. It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to...
Approved
Investigational
Matched Synonyms: … 2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid ... pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid …
Matched Description: … [A447] Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic ... [L14339] It was first authorized for use in the US in November 2001 and in Europe in April 2002. …
Dinoprostone
Dinoprostone is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.
Approved
Matched Synonyms: … (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid ... (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid ... (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
Matched Iupac: … (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid …
Matched Description: … As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce …
Matched Categories: … Genito Urinary System and Sex Hormones ... Fatty Acids ... Fatty Acids, Unsaturated …
1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE
Experimental
Matched Name: … 1-(PHENYLMETHYL)CYCLOPENTYL[(1S)-1-FORMYLPENTYL]CARBAMATE …
Matched Iupac: … 1-benzylcyclopentyl N-[(2S)-1-oxohexan-2-yl]carbamate …
Matched Iupac: … 1-benzylcyclopentyl N-[(2S)-1-oxohexan-2-yl]carbamate …
Iron sucrose
Iron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to less side effects than iron dextran, iron...
Approved
Matched Description: … chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Phosphate-removing Agents ... Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … FERRO SACCARATO FME …
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia ... Phosphate-removing Agents ... Acids, Acyclic ... Carboxylic Acids ... Hydroxy Acids …
Matched Products: … FERRO SACCARATO FME …
FG-2216
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.
Investigational
Matched Synonyms: … (((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Matched Iupac: … 2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid …
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid …
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …
Matched Iupac: … 1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid …
Matched Description: … Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride …
Matched Products: … Moxifloxacin Acino 400 mg Infusionslösung …
Efzofitimod
Efzofitimod (ATYR1923) is a fusion protein comprised of the immuno-modulatory domain of histidyl tRNA synthetase fused to the FC region of a human antibody. It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response in inflammatory disease states.
Investigational
Matched Synonyms: … Human IgG1Fc- iMod domain (amino acids 2-60) of human HARS fusion protein …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
Matched Description: … It is a selective modulator of neuropilin-2 that downregulates the innate and adaptive immune response …
ABBV-CLS-7262
Investigational
Matched Synonyms: … ({(2S)-1,4-bis[2-(4-chloro-3- fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2- yl}oxy)methyl hydrogen phosphate …
Matched Iupac: … diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate …
Matched Iupac: … diol {[(2S)-1,4-bis[2-(4-chloro-3-fluorophenoxy)acetamido]bicyclo[2.2.2]octan-2-yl]oxy}methyl hydrogen phosphate …
Cerulenin
Cerulenin is an antifungal agent whose activity interferes with or otherwise acts to prevent the formation of fatty acids and sterols. In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. In sterol synthesis, inhibits HMG-CoA synthetase activity. It is also shown to inhibit feeding and induce...
Experimental
Matched Synonyms: … (2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-carboxylic acid amide …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Matched Iupac: … (2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboximidic acid …
Matched Description: … and sterols. ... It is also shown to inhibit feeding and induce dramatic weight loss in mice. ... In fatty acid synthesis, reported to bind in equimolar ratio to b-keto-acyl-ACP synthase. …
Matched Categories: … Fatty Acid Synthesis Inhibitors …
Dermatan sulfate
Experimental
Matched Synonyms: … Chondroitinsulfuric acid type B …
Matched Categories: … Blood and Blood Forming Organs …
Matched Categories: … Blood and Blood Forming Organs …
Etoposide toniribate
Investigational
Matched Synonyms: … Carbonic acid, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 4-((5r,5ar,8ar,9s)-9-((4,6-o-(1r)-ethylidene-.beta ... 6-oxo-5,5a,6,8,8a,9-hexahydro-2h-furo(3',4':6,7)naphtho(2,3-d)(1,3)dioxol-5-yl)-2,6-dimethoxyphenyl carbonate …
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate …
Matched Iupac: … .0^{11,15}]hexadeca-1(9),2,7-trien-10-yl]-2,6-dimethoxyphenyl (2,2-dimethyl-1,3-dioxolan-4-yl)methyl carbonate …
Tagetitoxin
Tagetitoxin is a bacterial phytotoxin. It preferentially inhibits eukaryotic RNA polymerase.
Experimental
Matched Synonyms: … Acetoxy-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Matched Iupac: … acetyloxy)-7-amino-4-carbamoyl-4-hydroxy-8-(phosphonooxy)-9-oxa-3-thiabicyclo[3.3.1]nonane-1-carboxylic acid …
Matched Categories: … Acids, Acyclic ... Carboxylic Acids …
Cilofexor
Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis).
Investigational
Matched Synonyms: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
Matched Iupac: … 3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid …
Matched Description: … Cilofexor is under investigation in clinical trial NCT02943447 (Safety, Tolerability, and Efficacy of …
Matched Categories: … Acids, Heterocyclic …
(2R)-2-[(1R)-1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
Experimental
Matched Name: … -4-carboxylic acid ... -1-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-oxoethyl]-5-methylidene-2H-1,3-thiazine …
Matched Iupac: … -4-carboxylic acid ... -(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine …
Matched Iupac: … -4-carboxylic acid ... -(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine …
Senna leaf
Approved
Experimental
Matched Synonyms: … Ennae folium ... Sennae folium ... Sennae folium concisum …
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …
Matched Mixtures name: … SENNA LEAF and DOCUSATE SODIUM …
Displaying drugs 2126 - 2150 of 2788 in total