Displaying drugs 201 - 225 of 2378 in total
Carboxymethylcellulose
Carboxymethylcellulose is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and their hydroxyl groups bound to carboxymethyl groups. It is added in food products as a viscosity modifier or thickener and emulsifier. It is also one of the most common viscous polymers used in...
Approved
Investigational
Matched Description: … in the treatment of aqueous tear-deficient dry eye symptoms and ocular surface staining [A33029]. ... It is also one of the most common viscous polymers used in artificial tears, and has shown to be effective ... is a cellulose derivative that consists of the cellulose backbone made up of glucopyranose monomers and …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants ... Artificial Tears …
Matched Products: … Up and Up Lubricant Refreshing Tears ... Up and Up Lubricant Refreshing ... Up and Up Lubricant …
Matched Mixtures name: … Equate Day and Night Restore Tears ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) ... Refresh Trial Pack (refresh Tears, Refresh Liquigel and Refresh Ultra) …
Matched Categories: … Anorexigenic Agents & Respiratory and CNS Stimulants ... Artificial Tears …
Matched Products: … Up and Up Lubricant Refreshing Tears ... Up and Up Lubricant Refreshing ... Up and Up Lubricant …
Tribulus terrestris fruit
Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Tribulus Terrestris Fruit Powder ... Tribulus Terrestris Fruit Extract ... Tribulus Fruit …
Matched Name: … Tribulus terrestris fruit …
Matched Description: … Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. ... It is not an approved drug. …
Matched Name: … Tribulus terrestris fruit …
Matched Description: … Tribulus terrestris fruit is a plant/plant extract used in some OTC (over-the-counter) products. ... It is not an approved drug. …
Iron Dextran
Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Approved
Vet approved
Matched Description: … Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous …
Matched Mixtures name: … Threonate and Succinic Acid ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium …
Matched Products: … Cosmofer 50mg/ml Solution for injection and for infusion …
Matched Mixtures name: … Threonate and Succinic Acid ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium …
Matched Products: … Cosmofer 50mg/ml Solution for injection and for infusion …
TN-401
TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type human PKP2 gene.
Investigational
Matched Synonyms: … A native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and the wild-type …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …
Matched Description: … TN-401 is a native AAV9 capsid with a genomic cassette containing a cardiomyocyte-specific promoter and …
Eurotium amstelodami
Eurotium amstelodami allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, aspergillus amsterdami …
Matched Categories: … Non-Standardized Fungal Allergenic Extract …
Matched Categories: … Non-Standardized Fungal Allergenic Extract …
Phenazopyridine
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Phenazopyridine hydrochloride …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief ... ALMAX NX …
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Salts name: … Phenazopyridine hydrochloride …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief ... ALMAX NX …
Capsicum
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Zaxs Aches and Pain …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Matched Categories: … Non-Standardized Food Allergenic Extract ... Non-Standardized Plant Allergenic Extract …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Parecoxib
Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral...
Approved
Matched Synonyms: … N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide …
Matched Iupac: … N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide …
Matched Description: … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. ... Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx ... A letter of non-approval for parecoxib was issued by the FDA in 2005. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal …
Matched Products: … Dynastat Powder and Solvent for Solution for Injection 40mg …
Matched Iupac: … N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanamide …
Matched Description: … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. ... Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx ... A letter of non-approval for parecoxib was issued by the FDA in 2005. …
Matched Categories: … Antiinflammatory and Antirheumatic Products, Non-Steroids ... Antiinflammatory and Antirheumatic Products ... Analgesics, Non-Narcotic ... Anti-Inflammatory Agents, Non-Steroidal …
Matched Products: … Dynastat Powder and Solvent for Solution for Injection 40mg …
Tolnaftate
Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm. It is sold under several brand names, most notably Tinactin and Odor Eaters.
Approved
Investigational
Vet approved
Matched International brands: … NP-27 …
Matched Synonyms: … 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ... N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide ... O-2-Naphthyl m,N-dimethylthiocarbanilate …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Signature Black Bottle Tea Tree Antifungal Foot and Body Wash ... Woodwards Mycocide Clinical NS ... Up and Up Antifungal …
Matched Synonyms: … 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate ... N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide ... O-2-Naphthyl m,N-dimethylthiocarbanilate …
Matched Iupac: … N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide …
Matched Description: … and ringworm. ... It is sold under several brand names, most notably Tinactin and Odor Eaters. ... It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot …
Matched Mixtures name: … Terbinafine HCl Chlortimazole and Tolnaftate …
Matched Products: … Signature Black Bottle Tea Tree Antifungal Foot and Body Wash ... Woodwards Mycocide Clinical NS ... Up and Up Antifungal …
Coal tar
Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and heterocyclic compounds.
It has been...
Approved
Matched Description: … and eczema. ... Coal tars are complex and variable mixtures of phenols, polycyclic aromatic hydrocarbons (PAHs), and ... It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea …
Matched Mixtures name: … Pete and Pedro …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Matched Mixtures name: … Pete and Pedro …
Matched Products: … Skin and Scalp Body ... Skin and scalp ... Assured T And Plus …
Posoleucel
Investigational
Matched Synonyms: … specific T lymphocytes targeting BK virus, cytomegalovirus, human herpes virus-6, Epstein Barr virus, and …
Water
Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and rain, and is the major constituent of the fluids of organisms. As a chemical compound, a water molecule contains one oxygen and two hydrogen atoms that are connected by covalent bonds. Water is a...
Approved
Matched Description: … rain, and is the major constituent of the fluids of organisms. ... its solid state, ice; and gaseous state, steam (water vapor). ... Water (chemical formula: H2O) is a transparent fluid which forms the world's streams, lakes, oceans and …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … N/A ... Salinaax Eye Wash and Skin Flush ... Dorama-Neo …
Matched Mixtures name: … Medium Cuts and Scratches ... Good Neighbor Pharmacy Emergency Preparedness and First Aid Contains 167 Pieces ... SOLNARA Everything Blood circulation Nattokinase(Control blood pressure and Improve blood circulation …
Matched Products: … N/A ... Salinaax Eye Wash and Skin Flush ... Dorama-Neo …
Benzethonium
Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E …
Matched Mixtures name: … Benzethonium Chloride and Dyclonine Hydrochloride ... Benzethonium chloride and Dyclonine hydrochloride ... Benzethonium Chloride and Dyclonine Hydrochloride …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... LYSOL Healthy Touch Aloe Vera And Vitamin E with Moisturizers ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E …
Butylidenephthalide
Investigational
Matched Synonyms: … 3-butylidenephthalide, mixture of cis and trans isomers ... N-butylidenephthalide, (e)+(z) …
TRK-001
TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.
Investigational
Matched Synonyms: … Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … [A18903,A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover …
Matched Mixtures name: … Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Erythromycin and Benzoyl Peroxide …
Matched Products: … NO + ACNE CREMA PARA EL ACNE NON GRAS ® ... Stubborn Acne Daily Leave-ON Mask ... Daily Leave on Acne Treatment Mask …
Matched Mixtures name: … Clease and Treat ... Clean and Clear Advantage 2-in-1 Acne and Mark Eraser Kit ... Erythromycin and Benzoyl Peroxide …
Matched Products: … NO + ACNE CREMA PARA EL ACNE NON GRAS ® ... Stubborn Acne Daily Leave-ON Mask ... Daily Leave on Acne Treatment Mask …
Cetrorelix
Cetrorelix is a man-made hormone that blocks the effects of Gonadotropin Releasing Hormone (GnRH). GnRH controls another hormone that is called luteinizing hormone (LH), which is the hormone that starts ovulation during the menstrual cycle. When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not...
Approved
Investigational
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxopentan …
Matched Description: … Cetrorelix does not allow the premature release of these eggs to occur. ... When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …
Matched Description: … Cetrorelix does not allow the premature release of these eggs to occur. ... When undergoing hormone treatment sometimes premature ovulation can occur, leading to eggs that are not …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Cetrotide 0.25 mg powder and solvent for solution for injection …
Delolimogene mupadenorepvec
Investigational
Matched Synonyms: … Dna (synthetic human adenovirus 5/35 vector load703 human cd137 ligand and trimerized membrane-bound …
Cotsiranib
Investigational
Matched Synonyms: … interfering RNA (siRNA) therapeutic directed against transforming growth factor-beta 1 (TGF-beta 1) and …
PEP0101
PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …
Tetryzoline
Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Description: … [A7045, A231769] It has also been misused for non-therapeutic purposes as a causative drug for several ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... such as [povidone], [polyethylene glycol 400], [dextran], and [zinc sulfate]. …
Matched Mixtures name: … Murine Tears Plus 3 ... Redness reliever and Lubricant ... Up and Up Ultra Itchy Relief …
Matched Salts name: … Tetrahydrozoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops ... CLEAR TEARS® …
Matched Mixtures name: … Murine Tears Plus 3 ... Redness reliever and Lubricant ... Up and Up Ultra Itchy Relief …
Matched Salts name: … Tetrahydrozoline hydrochloride …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops ... CLEAR TEARS® …
Hiltonol
Investigational
Matched Synonyms: … homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …
Glycerin
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride ... NWI Artificial Tears Eye ... Spot Care Pink One …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Non-Standardized Chemical Allergen ... Other Cold and Cough Preparations …
Matched Products: … Im real TEA TREE SEBUM and Pore ... Given By Nature Green Tea Mask Sheet ... Eros Tasty Fruits …
Matched Mixtures name: … Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride ... NWI Artificial Tears Eye ... Spot Care Pink One …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Non-Standardized Chemical Allergen ... Other Cold and Cough Preparations …
Matched Products: … Im real TEA TREE SEBUM and Pore ... Given By Nature Green Tea Mask Sheet ... Eros Tasty Fruits …
Zenocutuzumab
Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Triptorelin
Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Synonyms: … pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 …
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Matched Iupac: … (2S)-N-[(2S)-5-carbamimidamido-1-[(2S)-2-[(carbamoylmethyl)carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl …
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Hormones and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …
Displaying drugs 201 - 225 of 2378 in total