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Displaying drugs 201 - 225 of 14531 in total

Insulin icodec

Insulin icodec is an ultra long-acting basal insulin analogue.
Approved
Investigational
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …

Bazedoxifene

Bazedoxifene is a third generation selective estrogen receptor modulator (SERM), developed by Pfizer following the completion of their takeover of Wyeth Pharmaceuticals. In late 2013, Pfizer received approval for bazedoxifene as part of the combination drug DUAVEE in the prevention (not treatment) of postmenopausal osteoporosis. It is approved in the...
Approved
Investigational
Matched Description: … It is approved in the European Union (marketed in Italy and Spain) and Japan as monotherapy. ... In 2013, the combination product containing conjugated estrogens and bazedoxifene was approved by the …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists ... Genito Urinary System and Sex Hormones ... conjugated estrogens and bazedoxifene ... Sex Hormones and Modulators of the Genital System …

Tauroursodeoxycholic acid

Tauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. It is a taurine conjugate of ursodeoxycholic acid with comparable therapeutic efficacy and safety, but a much higher hydrophilicity. Normally, hydrophilic bile acids regulates hydrophobic bile acids and...
Approved
Investigational
Matched Description: … It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and ... [A249060] Normally, hydrophilic bile acids regulates hydrophobic bile acids and their cytotoxic effects ... [A249080] Tauroursodeoxycholic acid is currently used in Europe to treat and prevent gallstones as …
Matched Categories: … sodium phenylbutyrate and ursodoxicoltaurine ... Bile Acids and Salts ... Bile and Liver Therapy ... Bile acids and derivatives ... Alimentary Tract and Metabolism …

Mipomersen

Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in...
Approved
Investigational
Matched Description: … Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic ... Due to this serious risk of liver toxicity, mipomersen sodium is only available to patients under the ... Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein …
Matched Salts name: … Mipomersen sodium …
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …

Mycophenolic acid

Mycophenolic acid is a potent immunosuppressant agent that inhibits de novo purine biosynthesis. It was derived from Penicillium stoloniferum, and has also shown antibacterial, antifungal and antiviral properties. . Mycophenolic acid is used in immunosuppressive regimens as part of a triple therapy that includes a calcineurin inhibitor (ciclosporin or tacrolimus)...
Approved
Investigational
Matched Description: … and antiviral properties. ... to optimize efficacy and minimize toxicity. ... [L42165] It was derived from _Penicillium stoloniferum_, and has also shown antibacterial, antifungal …
Matched Salts name: … Mycophenolate sodium …
Matched Categories: … Mycophenolic Acid and Prodrugs ... Antineoplastic and Immunomodulating Agents …

Polyestradiol phosphate

Polymeric phosphoric acid ester of estradiol.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents …

Fulvestrant

Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy. It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. While it is used as monotherapy for the...
Approved
Investigational
Matched Description: … Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal ... It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists …

Canrenoic acid

Canrenoic acid (as the salt potassium canrenoate) is an aldosterone antagonist. Like spironolactone, it is a prodrug, which is metabolized to canrenone in the body.
Approved
Withdrawn
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Hormone Antagonists …

Aluminum zirconium trichlorohydrex gly

Aluminum zirconium trichlorohydrex gly is a common active ingredient in deodorant and antiperspirant products for the over-the-counter use. It is consisted of a mixture of monomeric and polymeric Zr4+ and Al3+ complexes with hydroxide, chloride and glycine. The compound forms a colloidal plug in sweat pores, preventing sweat from leaving...
Approved
Experimental
Matched Description: … It is consisted of a mixture of monomeric and polymeric Zr4+ and Al3+ complexes with hydroxide, chloride ... and glycine. ... Aluminum zirconium trichlorohydrex gly is a common active ingredient in deodorant and antiperspirant …

Desvenlafaxine

Desvenlafaxine (O-desmethylvenlafaxine) is the 0-demetyhlated active metabolite of venlafaxine. Like its parent drug, desvenlafaxine is also an antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitor (SNRI) class.[A261266,A261266] It was approved by the FDA in 2008 for the treatment of adults with major depressive disorder (MDD).[L6016,A261271] MDD is a highly...
Approved
Investigational
Matched Description: … a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and ... [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine …
Matched Categories: … Serotonin and Noradrenaline Reuptake Inhibitors …

Tiopronin

Tiopronin is a prescription thiol drug used primarily in the treatment of severe homozygous cystinuria. Patients with cystinuria excrete high levels of cystine in their urine and are at risk for kidney stone formation. Tiopronin is used as a second-line therapy to control the rate of cystine precipitation and excretion,...
Approved
Investigational
Matched Description: … of the non-pharmacological first line treatment consisting of increased fluid intake, restriction of sodium ... and protein, and urinary alkalinization. ... , and prevent kidney stone formation. …
Matched Categories: … Reducing and Complexing Thiol ... Amino Acids, Peptides, and Proteins ... Genito Urinary System and Sex Hormones …

Light green SF yellowish

Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in histological applications and other labratory settings, and usually exists as a disodium salt. The maximum absorption of light green SF...
Approved
Experimental
Matched Description: … It is used in histological applications and other labratory settings, and usually exists as a disodium ... discontinued from the market due to low popularity which are possibly due to low durability of the dye and …

Edetate disodium anhydrous

Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Approved
Vet approved
Matched Description: … Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis …

Folic acid

Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction ... cofactor for enzymes involved in DNA and RNA synthesis. ... therefore prevent the formation of DHF and THF. …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... and Succinic Acid …
Matched Salts name: … Folate sodium …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... ferrous sulfate and folic acid ... ferrous fumarate and folic acid …

Dasiglucagon

Dasiglucagon is a glucagon analog that acts to increase blood sugar levels. It consists of 29 amino acids similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and chemical stability in its drug formulation. In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia...
Approved
Investigational
Matched Description: … similar to endogenous glucagon; however, it contains seven substituted amino acids for improved physical and ... L39195] In March 2021, the FDA approved dasiglucagon to treat severe hypoglycemia in patients six years and ... Hypoglycemia is a common side effect of antidiabetic treatments, most notably insulin and sulfonylureas …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins …

Quinestrol

The 3-cyclopentyl ether of ethinyl estradiol.
Approved
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Magnesium silicate

Magnesium silicate is a compound of magnesium oxide and silicon. It is the magnesium salt of silicic acid containing an unspecified amount of water. The molecular formula can be expressed more clearly as MgSiO3.xH2O. It is known as talc and it presents many uses in the cosmetic industry, food industry...
Approved
Matched Description: … [T186] It is known as talc and it presents many uses in the cosmetic industry, food industry and pharmaceutical ... Magnesium silicate is a compound of magnesium oxide and silicon. …
Matched Categories: … Alimentary Tract and Metabolism ... Aluminum and magnesium containing antacids …

Ajmaline

An alkaloid found in the root of Rauwolfia serpentina, among other plant sources. It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very...
Approved
Experimental
Matched Description: … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a ... It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac ... many years as a drug to challenge the conduction system of the heart in cases of bundle branch block and …
Matched Categories: … Ajmaline and derivatives ... Sodium Channel Blockers ... Voltage-Gated Sodium Channel Blockers …

Tenapanor

Tenapanor is a novel, small molecule medication approved in September 2019 for the treatment of constipation-predominant irritable bowel-syndrome (IBS-C). It was first designed and synthesized in 2012. As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first and currently only medication within its class[A185489,A185492,A185495] and...
Approved
Investigational
Matched Description: … [A185492] As an inhibitor of the sodium/hydrogen exchanger isoform 3 (NHE3) transporter, it is the first ... and currently only medication within its class[A185489,A185492,A185495] and therefore exists as a novel ... [L8558] It was first designed and synthesized in 2012. …
Matched Categories: … Alimentary Tract and Metabolism ... Sodium-Hydrogen Exchanger 3 Inhibitor ... Sodium/Hydrogen Exchanger 3 (NHE3) Inhibitors …

Selenic acid

Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of DB11135, an essential trace mineral for human health.
Approved
Matched Mixtures name: … Prenatal and Post Partum Supplement ... Beta A With Vitamins C and E Plus Selenium ... One Daily Vitamin and Mineral Dietary Supplement …
Matched Salts name: … Sodium selenate …
Matched Categories: … sodium selenate ... Diet, Food, and Nutrition ... Alimentary Tract and Metabolism …

Esterified estrogens

Esterified estrogens contain a mixture of estrogenic substances; the principle component is estrone. Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that the total is not <90%. Esterified estrogens are a man-made mixture of estrogens that are used to treat symptoms of...
Approved
Matched Description: … Preparations contain 75% to 85% sodium estrone sulfate and 6% to 15% sodium equilin sulfate such that ... It is being also for the prevention and treatment of osteoporosis. …
Matched Mixtures name: … Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone ... Esterified Estrogens and Methyltestosterone …

Pentetreotide

Pentetreotide has been used in trials studying the diagnosis of Cushing's syndrome.
Approved
Investigational
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists ... Indicators and Reagents ... Amino Acids, Peptides, and Proteins ... Pituitary Hormone Release Inhibiting Hormones …

Nomegestrol acetate

Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Approved
Investigational
Matched Description: … therapy, and for the treatment of gynecological disorders. ... Nomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) …

Dehydrocholic acid

Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Salts name: … Dehydrocholate sodium …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …

Norethisterone

Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19-nortestosterone-derived class of progestins. It is further classified as a second-generation progestin, along with levonorgestrel and its derivatives, and is the active form of several other progestins including norethynodrel and lynestrenol. Norethisterone mimics the actions of endogenous...
Approved
Matched Description: … hormone replacement therapy. ... Norethisterone, also known as norethindrone, is a synthetic progestational hormone belonging to the 19 ... derivatives, and is the active form of several other progestins including [norethynodrel] and [lynestrenol …
Matched Mixtures name: … Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol and Ferrous Fumarate ... Norethindrone and Ethinyl Estradiol, and Ferrous Fumarate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Sex Hormones and Insulins ... norethisterone and estrogen ... norethisterone and estrogen ... norethisterone and ethinylestradiol …
Displaying drugs 201 - 225 of 14531 in total