Displaying all 16 targets
Serine/threonine-protein kinase MRCK gamma
Matched Polypeptides synonyms: … CDC42-binding protein kinase gamma ... Myotonic dystrophy kinase-related CDC42-binding kinase gamma …
Matched Polypeptides general function: … May act as a downstream effector of CDC42 in cytoskeletal reorganization. …
Matched Polypeptides general function: … May act as a downstream effector of CDC42 in cytoskeletal reorganization. …
Activated CDC42 kinase 1
Matched Polypeptides name: … Activated CDC42 kinase 1 …
Matched Polypeptides specific function: … Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1 …
Matched Name: … Activated CDC42 kinase 1 …
Matched Polypeptides specific function: … Downstream effector of CDC42 which mediates CDC42-dependent cell migration via phosphorylation of BCAR1 …
Matched Name: … Activated CDC42 kinase 1 …
Breakpoint cluster region protein
Matched Polypeptides specific function: … GTPase-activating protein for RAC1 and CDC42. ... Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. …
Cell division control protein 42 homolog
Matched Polypeptides specific function: … Mediates CDC42-dependent cell migration. …
RalA-binding protein 1
Matched Polypeptides specific function: … Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. …
Ras GTPase-activating-like protein IQGAP1
Matched Polypeptides general function: … Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. …
Serine/threonine-protein kinase PAK 3
Matched Polypeptides general function: … Acts as downstream effector of the small GTPases CDC42 and RAC1. ... Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent …
Serine/threonine-protein kinase PAK 2
Matched Polypeptides general function: … Acts as downstream effector of the small GTPases CDC42 and RAC1. ... Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent …
Ras-related protein Rab-11A
Matched Polypeptides specific function: … Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis …
Serine/threonine-protein kinase PAK 5
Matched Polypeptides general function: … Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in …
Cyclin-dependent kinase 5
Matched Polypeptides specific function: … PAK1, RAC1, RHOA, CDC42) or microtubule-binding proteins (e.g. ... MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42 …
Serine/threonine-protein kinase PAK 1
Matched Polypeptides general function: … Activated by interaction with CDC42 and RAC1. ... Functions as GTPase effector that links the Rho-related GTPases CDC42 and RAC1 to the JNK MAP kinase …
Protein kinase C epsilon type
Matched Polypeptides specific function: … Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration ... morphological change independently of its kinase activity, by inhibition of RHOA pathway, activation of CDC42 …
Serine/threonine-protein kinase PAK 4
Matched Polypeptides general function: … Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in …
Calcium and integrin-binding protein 1
Matched Polypeptides general function: … Positively regulates cell migration on fibronectin in a CDC42-dependent manner, the effect being negatively …
Protein kinase C
Matched Polypeptides specific function: … Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration ... morphological change independently of its kinase activity, by inhibition of RHOA pathway, activation of CDC42 …
Matched Polypeptides general function: … In migrating astrocytes, forms a cytoplasmic complex with PARD6A and is recruited by CDC42 to function …
Matched Polypeptides general function: … In migrating astrocytes, forms a cytoplasmic complex with PARD6A and is recruited by CDC42 to function …
Displaying all 16 targets