Uncoupling Agents

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DBCAT000642Pharmacologic class

Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes. A DrugBank category of 8 drugs. 2 of them are approved.

Also known as
Agents, Uncoupling
Drugs

What you can answer from here — as of August 24, 2016

8DrugsEach linked to its full drug card
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11Drug targetsEvery drug–target pair in the class, with bond type
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5Marketed productsAcross the regions we cover, with dosage forms and routes
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2Routes of administrationHow the drugs in this class are given
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Which targets do Uncoupling Agents share, and which companies have late-stage candidates in this class?

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