Guanylate Cyclase Stimulators

Guanylate Cyclase Stimulators
Accession Number

Not Available

DrugDrug Description
RiociguatA stimulator of soluble guanylate cyclase indicated for the management of persistent or recurrent chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.
VericiguatA soluble guanylate cyclase stimulator used to reduce heart failure-related hospitalization and cardiovascular death in patients with chronic systolic heart failure.
Drugs & Drug Targets
RiociguatSerum albumincarrier
RiociguatAlpha-1-acid glycoprotein 1carrier
RiociguatGuanylate cyclase soluble subunit alpha-2target
RiociguatATP-binding cassette sub-family G member 2transporter
RiociguatCytochrome P450 1A1enzyme
RiociguatCytochrome P450 3A4enzyme
RiociguatCytochrome P450 2C8enzyme
RiociguatCytochrome P450 2J2enzyme
RiociguatP-glycoprotein 1transporter
VericiguatUDP-glucuronosyltransferase 1-9enzyme
VericiguatUDP-glucuronosyltransferase 1-1enzyme
VericiguatP-glycoprotein 1transporter
VericiguatATP-binding cassette sub-family G member 2transporter
VericiguatSerum albumincarrier
VericiguatGuanylate cyclase soluble subunit beta-1target