Acute monocytic leukemia (DBCOND0022173)
Identifiers
- Synonyms
- Acute monocytic leukaemia / Leukemia, Monocytic, Acute / Acute Monocytic Leukemia / Acute monoblastic/monocytic leukemia / Monocytic leukaemia, acute / Acute monocytic leukemia (disorder) / Monocytic leukemia, acute / Acute monocytic leukemia (morphologic abnormality) / Monocytic leukemia (disorder) / Leukaemia monoblastic acute / Acute monoblastic leukaemia / Leukemia monoblastic acute / FAB type M5a (qualifier value) / Acute monoblastic leukemia
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Cyclophosphamide A nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.- DNAtarget
- Cytochrome P450 2B6enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C19enzyme
- Cytochrome P450 2A6enzyme
- Cytochrome P450 2C18enzyme
- Cytochrome P450 2C8enzyme
- Cytochrome P450 3A5enzyme
- Nuclear receptor subfamily 1 group I member 2target
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT05566054 Venetoclax and Azacitidine Combined With Chidamide (VAC) for the Treatment of Newly Diagnosed Acute Monocytic Leukemia treatment 2 recruiting NCT06504459 Venetoclax in Combination With Cladribine and Cytarabine Alternating With Azacitidine Plus Venetoclax for the Treatment of Newly Diagnosed Monocytic AML and Active Signaling Mutated AML treatment 2 not_yet_recruiting NCT02527174 A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia treatment 1 withdrawn NCT00531583 Autologous Peripheral Blood Stem Cell Transplantation With In Vivo Purging as an Alternate Stem Cell Transplantation Program for Pts w/AML in 1st & 2nd Complete Remission w/no HLA Matched Related Donor No drug interventions treatment Not Available completed NCT05313958 Treateament of Newly Diagnosed Acute Monocytic Leukemia in Children treatment 2 / 3 recruiting