Diarrhoea Predominant Irritable Bowel Syndrome (DBCOND0075933)

Identifiers

Synonyms
Diarrhea-predominant Irritable Bowel Syndrome / IBS, Diarrhea Predominant / Irritable Bowel Syndrome With Diarrhea / Diarrhea Predominant Irritable Bowel Syndrome / Diarrhea- Predominant Irritable Bowel Syndrome / Diarrhea Dominant Irritable Bowel Syndrome / Diarrhoea predominant irritable bowel syndrome / Irritable bowel syndrome with diarrhea (disorder) / Irritable bowel syndrome without diarrhea / Irritable colon / Colitis mucous / Mucous colitis / Colon spastic / Spastic colon / Irritable colon syndrome / Functional bowel syndrome / Irritable bowel / Irritable bowel syndrome / Irritable colon (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Eluxadoline
A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02111603
Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acidstreatment4completed
NCT01896583
A Phase 2 Pilot Study to Assess ASP7147 in Patients With Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)No drug interventionstreatment2completed
NCT01373034
The Effects of Soy Dietary Fiber in Adults With Diarrhea Predominant Irritable Bowel SyndromeNo drug interventionstreatmentNot Availableunknown_status
NCT00616200
Effects of a Very Low Carbohydrate Diet on Symptoms of Irritable Bowel Syndrome (IBS)No drug interventionstreatmentNot Availablecompleted
NCT06346847
Study to Assess Effects of Postbiotic vs Placebo in Participants With Diarrhea-predominant IBSNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04095988
Allogeneic Microbiota-reconstitution (AMR) in Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)No drug interventionstreatmentNot Availableunknown_status
NCT01350570
Acupuncture for Patients With Diarrhea-predominant IBS or Functional Diarrhea: a Randomized Controlled Trialtreatment2 / 3completed
NCT05687435
Changyanning Tablet for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)No drug interventionstreatment2 / 3not_yet_recruiting
NCT02251483
Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial OvergrowthNo drug interventionssupportive_careNot Availablecompleted
NCT02358694
Safety and Tolerability of Serum Derived Bovine Immunoglobulin in Children With Diarrhea Predominant IBSNo drug interventionssupportive_careNot Availablecompleted
NCT02190526
Effects of Mesalamine and Amitriptyline on Irritable Bowel Syndrometreatment4withdrawn
NCT01637714
The Effects of Multi-strain Probiotics in Adults With Diarrhea Predominant Irritable Bowel SyndromeNo drug interventionstreatmentNot Availableunknown_status
NCT01100684
Study of Asimadoline to Treat Diarrhea-Predominant Irritable Bowel Syndrome (D-IBS)treatment3completed
NCT01414244
Glutamine for the Treatment of Patients With Irritable Bowel Syndrometreatment2completed
NCT05593367
Effects of Vitamin D on Gut Microbiota, Intestinal Barrier in IBS-D PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT01870895
A Study to Assess the Efficacy and Safety of YM060 in Female Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS)treatment3completed
NCT03977155
Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)No drug interventionstreatment2completed
NCT05369884
Efficacy and Safety of WPQW Granule for Overlap of NERD and IBS-DNo drug interventionstreatment0unknown_status
NCT03099785
Rifamycin SV-MMX® 600 mg Tablets Administered Three or Two Times Daily to Patients With IBS-Dtreatment2completed
NCT02612649
Special Drug Use Surveillance of Irribow in Female PatientsNot AvailableNot Availablecompleted
NCT02163213
Serum-Derived Bovine Immunoglobulin /Protein Isolate (SBI) 5.0 g Bid on Nutritional Status in Subjects With IBS-DNo drug interventionssupportive_careNot Availablecompleted
NCT02728063
Lactibiane Tolérance® in Individuals Suffering From Irritable Bowel Syndrome With Diarrheal PredominanceNo drug interventionstreatmentNot Availablecompleted
NCT02239926
Effect of Ranolazine on Gastrointestinal Motor Function and Pain in Patients With IBS-Dtreatment2 / 3terminated
NCT01094041
Gluten Intolerance in Patients With Diarrhea Predominant Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT02538692
Tong-Xie-Yao-Fang Granules for Diarrhea-predominant Irritable Bowel Syndrometreatment2 / 3completed
NCT01736423
A Long Term Study of YM060 in Female Patients With Diarrhea-predominant Irritable Bowel Syndrometreatment3completed
NCT01358708
Treatment of Diarrhea-predominant Irritable Bowel Syndrome (IBS-D) With LACTEOL® 340 mgtreatment3terminated
NCT00619125
Proposal Evaluating Time-specific Relationships Between Variables of Pain, Stress, and Bloating in IBS Diarrhea and Constipation Symptoms Using a Palm PilotNo drug interventionsNot AvailableNot Availablecompleted
NCT04855799
GI Permeability Change in Response to Aquamin®No drug interventionstreatment2active_not_recruiting
NCT06153420
Study of the Research Medicine CIN-103 in Adults With Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D).No drug interventionstreatment2recruiting
NCT06612411
B.Subtilis Attenuate Symptoms in Diarrhea-predominant Irritable Bowel Syndrome by Increasing Hypoxanthine BiosynthesisNo drug interventionstreatment0recruiting
NCT04053790
Lactobacillus LB as Treatment for Irritable Bowel Syndrome With Predominance of Diarrhea (IBS-D)treatment4completed
NCT03221790
Effect of FODMAPs on Mucosal Inflammation in IBS PatientsNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06297421
Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young AdultsNo drug interventionstreatment2not_yet_recruiting
NCT02431533
The Efficacy of PX0612 In The Treatment Of Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT05754177
Safety and Efficacy of a Probiotic Supplement in IBS-DNo drug interventionssupportive_careNot Availablerecruiting
NCT06543498
The Effect of Dietary Supplementation on Intestinal Barrier Function in IBS-DNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT02959983
Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Usetreatment4completed
NCT05277428
Clinical Study to Evaluate the IBS Symptoms Improving Effect and Safety of GTB1No drug interventionsotherNot Availablecompleted
NCT01543178
Irritable Bowel Syndrome With Diarrhea (IBS-D) Rifaximin Re-Treatment Studytreatment3completed
NCT03270085
Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorptionother2completed
NCT04557215
Efficacy and Safety of Rifaximin With NAC in IBS-Dtreatment1 / 2completed
NCT04214470
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBSNo drug interventionsNot AvailableNot Availableunknown_status
NCT05379036
Intestinal Permeability and Intestinal Microbiota in Irritable Bowel SyndromeNo drug interventionstreatment4unknown_status
NCT02320318
12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)treatment3withdrawn
NCT02822118
Therapeutic Effect of Chang'an I Recipe on Irritable Bowel Syndrome With DiarrheaNo drug interventionstreatment1 / 2completed
NCT04129619
A Comparison of the Effects of ORP-101 Versus Placebo in Adult Patients With Irritable Bowel Syndrome With Diarrhea (IBS-D)treatment2completed
NCT05453916
Comparing the Efficacy of Nitazoxanide Versus Rifaximin in Adult Patients With Irritable Bowel Syndrome Without Constipationtreatment1 / 2recruiting
NCT04806386
The Role of Fiber in the Prevention and Treatment of Fecal IncontinenceNo drug interventionstreatmentNot Availablerecruiting
NCT04662957
Multi Strain Probiotic Preparation in Patients With Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT03441581
Eluxadoline Bile Acid Malabsorption (BAM) Studytreatment4completed
NCT05702255
Self- Administered Acupressure for Diarrhea Predominant Irritable Bowel SyndromeNo drug interventionssupportive_careNot Availablecompleted
NCT05867550
To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrheatreatment4completed
NCT04492787
Efficacy and Safety of Changkang Granule in the Treatment of Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)No drug interventionstreatment2completed
NCT01497847
Post-Infectious Irritable Bowel Syndrome (PI-IBS)No drug interventionsNot AvailableNot Availablecompleted
NCT05130047
Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM)treatment2completed
NCT03245645
FODMAP Reintroduction in Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT02757105
Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial of BEKINDA (Ondansetron 12 mg Bimodal Release Tablets) for Diarrhea Predominant Irritable Bowel Syndrome (IBS-D)treatment2completed
NCT05311293
Study on the Molecular Mechanism of Diarrhea-predominant Irritable Bowel Syndrome With Anxiety and Depression Based on Multi-omics Correlation AnalysisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03729271
Hydrogen Breath Test an Instrument to Predict Rifaximin-Response in Irritable Bowel Syndrome Predominant Diarrheatreatment4recruiting
NCT03557788
Changes in Microbiota and Metabolomic Profile Between Rifaximin Responders and Non-responders In Diarrhoea-Predominant Irritable Bowel Syndromebasic_science4completed
NCT03806959
Interest of Pan Capsule in Symptomatic Patients Suspected of Irritable Bowel Syndrome Requiring ColonoscopyNo drug interventionsdiagnosticNot Availablecompleted
NCT01303224
Ibodutant for Relief of Irritable Bowel Syndrome With Diarrhoea (IBS-D)treatment2completed
NCT02107196
12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)treatment3completed
NCT04950296
To Study the Efficacy and Safety of L. Plantarum UALp-05TM in Diarrhea- Predominant-irritable Bowel SyndromeNo drug interventionsotherNot Availablecompleted
NCT05719896
Efficacy and Safety of DT01 Tablets in Patients With Irritable Bowel Syndrome With DiarrheaNo drug interventionstreatment2not_yet_recruiting
NCT05646186
Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel SyndromeNo drug interventionstreatmentNot Availableunknown_status
NCT00552565
Efficacy Study of Rezular (Arverapamil) in the Treatment of Irritable Bowel Syndrome With Diarrhea (IBS-D)treatment3completed
NCT02120027
52-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D)treatment3terminated
NCT05523427
Probiotics as Adjuvant Therapy in the Management of Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT04484467
Efficacy and Safety of a Food Supplement With Standardized Menthol, Limonene, and Gingerol Content in Patients With Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT04899869
Faecal Microbiota Transplantation in Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT06432569
Evaluation of Butyrate and Palmitoylethanolamide in IBS Patients (B/P3_1)No drug interventionstreatmentNot Availableenrolling_by_invitation
NCT06247046
A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-DNo drug interventionstreatment3recruiting
NCT04830410
The Effects of Carbohydrates in Irritable Bowel SyndromeNo drug interventionstreatmentNot Availablerecruiting
NCT01177410
Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrheatreatment2completed
NCT03997708
A Mediterranean Approach to Low FODMAP Diet (MED-LFD) for Managing IBS SymptomsNo drug interventionssupportive_careNot Availablecompleted
NCT05339243
Evaluating the Safety and Efficacy of the Probiotic Bifidobacterium Longum ES1 and the Post Biotic Heat-treated Bifidobacterium Longum ES1 (HT-ES1) on IBS Symptom Severity in Patients With Diarrhoea Predominant Irritable Bowel SyndromeNo drug interventionsotherNot Availablecompleted
NCT02419963
Analyzing IBS to Identify Biomarkers and Microbiome SignaturesNo drug interventionsbasic_scienceNot Availablecompleted
NCT02661425
Retrospective Study of IBS-D Patients Previously Receiving SBINo drug interventionsNot AvailableNot Availablecompleted
NCT00589771
Saccharomyces Boulardii in Irritable Bowel SyndromeNo drug interventionstreatment3completed