NCT00003203
Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors treatment 2 completed NCT00477503
Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA treatment 1 terminated NCT00031590
Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma treatment 2 terminated NCT01985451
Pemetrexed and Temozolomide in Treating Patients With Relapsed Primary Central Nervous System Lymphoma （PCNSL） treatment 2 unknown_status NCT00109798
Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma treatment Not Available withdrawn NCT00040911
Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin Lymphoma No drug interventions supportive_care Not Available completed NCT00107471
Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma treatment 1 / 2 terminated NCT05308407
POWER UP: Participating Online While Exercising to Recover Using Play No drug interventions supportive_care Not Available suspended NCT00899834
DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma No drug interventions Not Available Not Available completed NCT00400816
Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma treatment 2 completed NCT01067196
Outcomes Study of Late Effects After Proton RT for Pediatric Tumors of the Brain, Head, and Neck No drug interventions Not Available Not Available completed NCT00003096
Gene Testing to Help in the Diagnosis and Treatment of Childhood Brain Tumors No drug interventions Not Available Not Available completed NCT04351035
National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry No drug interventions Not Available Not Available completed NCT00003935
Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma treatment 1 completed NCT00003625
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma treatment 1 completed NCT00187226
A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects No drug interventions treatment 2 completed NCT05235074
OH2 Oncolytic Viral Therapy in Central Nervous System Tumors treatment 1 / 2 recruiting NCT00002944
Combination Chemotherapy in Treating Children With Progressive Brain Tumors treatment 3 completed NCT00005812
Temozolomide in Treating Patients With Leptomeningeal Metastases From a Solid Tumor or Lymphoma treatment 2 terminated NCT00607984
Administration of High Dose Thiotepa and Melphalan With Autologous Hematopoietic Stem Cell Transplant in Children and Adolescents With Solid Tumors treatment Not Available unknown_status NCT00407433
Clinical Studies of Gemcitabine-Oxaliplatin treatment 2 completed NCT01735747
Temozolomide, Nedaplatin, Vincristine, and Radiotherapy as First-line Treatment in Newly Diagnosed Primary CNS Lymphoma treatment 2 unknown_status NCT00935545
Study of Peptide Vaccination With Tumor Associated Antigens Mixed With Montanide in Patients With CNS Tumors treatment 1 completed NCT00945828
Assessing the Effectiveness of Individual Education Plans for Childhood Cancer Survivors No drug interventions supportive_care Not Available completed NCT00876993
Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors treatment 1 completed NCT00002875
Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma treatment 3 completed NCT00003141
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors treatment 1 completed NCT01135563
Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS Tumours treatment 1 completed NCT01052363
OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas treatment 1 withdrawn NCT00066248
Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment supportive_care 2 completed NCT00152126
Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas treatment Not Available completed NCT02793466
Durvalumab in Pediatric and Adolescent Patients treatment 1 completed NCT00047320
Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors treatment 2 completed NCT00003573
Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma treatment 2 completed NCT05081180
Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors treatment 1 recruiting NCT02462629
Study of BLZ-100 in Pediatric Subjects With CNS Tumors other 1 completed NCT01164189
Bevacizumab in Recurrent Grade II and III Glioma treatment 2 completed NCT03050450
Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors treatment 1 terminated NCT05386108
Study of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to ER+/HER-2- Breast Cancer treatment 1 / 2 recruiting NCT04859543
Pediatric Prospective Personalized Immune and Target Identification Trial No drug interventions diagnostic Not Available recruiting NCT00629187
Safety Study of High Dose Temozolomide to Treat Relapsed/Refractory Central Nervous System (CNS) Malignancy treatment 1 terminated NCT03188354
Diagnostic Assessment of 18F-fluciclovine and 18F-FDG -PET/MRI of Primary Central Nervous System Lymphoma No drug interventions diagnostic Not Available completed NCT02095353
Comparison of Contrast Agents for MRI Perfusion Analysis in Brain Tumor Patients No drug interventions Not Available Not Available terminated NCT02692898
Biomarker Analysis of Central Nervous System Tumors No drug interventions Not Available Not Available terminated NCT01931098
Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab treatment 2 completed NCT00822432
Coproporphyrine Isomers and Methotrexate Elimination No drug interventions Not Available Not Available completed NCT01582152
Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma treatment 1 / 2 terminated NCT04096716
Mapping Draining Lymph Nodes in CNS Malignancies diagnostic 1 terminated NCT00185848
Assessing the Suitability of an Imaging Probe for Use in Clinical Cell and Gene Therapy Trials in Cancer and Rheumatoid Arthritis No drug interventions diagnostic 1 completed NCT03257631
A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors treatment 2 completed NCT03434262
SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors treatment 1 completed NCT03147989
Retrospective Study of MRI With MULTIHANCE at 0.10 and 0.05 mmol/Kg Dose in CNS Patients Not Available Not Available completed NCT04671368
Diagnostic Efficiency of Artificial Intelligence for Surgical Neuropathology No drug interventions diagnostic Not Available unknown_status NCT01180881
Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment No drug interventions Not Available Not Available active_not_recruiting NCT05835687
Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors No drug interventions treatment 1 recruiting NCT01579253
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients No drug interventions Not Available Not Available unknown_status NCT05850377
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas Not Available Not Available not_yet_recruiting NCT03750188
Evaluation of Safety and Efficacy of ProHance in Pediatric Patients <2yrs Not Available Not Available completed NCT00328458
EPO906 Plus Radiation Therapy for the Treatment of Cancer Patients treatment 1 completed NCT02291822
Retrospective Study of MRI in Pediatric Patients Not Available Not Available completed NCT04541082
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms No drug interventions treatment 1 recruiting NCT00329589
A Trial Using Velcade Plus Chemoradiation for Central Nervous System, Head and Neck, and Cervical Cancer Patients treatment 1 completed NCT04525014
RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Solid and Central Nervous System Tumors treatment 1 terminated NCT04023669
Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors treatment 1 active_not_recruiting NCT05270707
HyperArc Registry Study No drug interventions Not Available Not Available recruiting NCT04773782
A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling treatment 1 / 2 active_not_recruiting NCT06441331
Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors treatment 1 not_yet_recruiting NCT05300113
Artificial Intelligence Neuropathologist No drug interventions Not Available Not Available recruiting NCT04732065
ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors treatment 1 recruiting NCT05222165
Study With Infigratinib in Subjects With Advanced Solid and CNS Tumors or Recurrent or Progressive Low-Grade Glioma With Selected FGFR1-3 Alterations treatment 1 / 2 withdrawn NCT06528691
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors treatment 2 recruiting NCT05480904
Characterizing Sleep Among Long-term Survivors of Childhood Cancer No drug interventions Not Available Not Available recruiting NCT05952687
Trial of Idasanutlin and Selinexor Therapy for Children With Progressive/Relapsed AT/RT or Extra-CNS Malignant Rhabdoid Tumors treatment 1 withdrawn NCT03838042
INFORM2 Study Uses Nivolumab and Entinostat in Children and Adolescents With High-risk Refractory Malignancies treatment 1 / 2 recruiting NCT06322342
Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent No drug interventions diagnostic 2 recruiting NCT04334239
Effectiveness of Care in Certified Cancer Centres in Germany No drug interventions Not Available Not Available completed NCT02988726
Antineoplaston Therapy in Treating Patients With Neurofibroma and Schwannoma treatment 2 terminated NCT04706676
Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer No drug interventions prevention Not Available recruiting NCT06036394
Artificial Intelligence in CNS Radiation Oncology No drug interventions Not Available Not Available active_not_recruiting NCT05982691
Development of Asian Consortium for Data Collection and Clinical Trial of CNS Tumors No drug interventions Not Available Not Available recruiting NCT02684838
Vigilant ObservatIon of GlIadeL WAfer ImplaNT Registry No drug interventions Not Available Not Available active_not_recruiting NCT00238264
Radiation Therapy in Treating Young Patients With Gliomas No drug interventions treatment 2 completed NCT03496402
Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) No drug interventions other Not Available recruiting NCT04852354
Tissue Collection for Drug Screening and Bioanalysis No drug interventions Not Available Not Available recruiting NCT06104488
A Study of Avutometinib for People With Solid Tumor Cancers treatment 1 recruiting NCT00078988
High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas treatment 3 completed NCT00077207
Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma treatment Not Available completed NCT00006024
Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma treatment 1 completed NCT05978557
Brain Slice Explants to Predict Drug Response in Brain Tumors No drug interventions Not Available Not Available recruiting NCT01595126
Longitudinal Study of Biomarkers No drug interventions Not Available Not Available unknown_status NCT03452774
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry No drug interventions Not Available Not Available recruiting NCT02496520
Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults No drug interventions treatment 1 / 2 completed NCT00716976
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy supportive_care 3 completed NCT06363201
Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours No drug interventions supportive_care Not Available not_yet_recruiting NCT00027846
Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma treatment 2 completed NCT06054295
Somatic Mosaicism in Twins Discordant for Childhood Cancer No drug interventions Not Available Not Available recruiting NCT04185038
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors No drug interventions treatment 1 recruiting NCT03052738
Medical Marijuana in the Pediatric Central Nervous System Tumor Population No drug interventions Not Available Not Available completed NCT00085098
Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor treatment 3 completed NCT02012699
Integrated Cancer Repository for Cancer Research No drug interventions Not Available Not Available recruiting NCT03981016
Medical and Surgical Management of Patients With Brain Metastases No drug interventions other Not Available completed NCT00002594
Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors treatment 2 completed NCT02932280
Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment treatment 1 / 2 active_not_recruiting NCT04743310
Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System treatment 2 recruiting NCT05511714
Expanded Access [11C] Methionine PET Imaging Not Available Not Available available NCT05746104
Second Window Indocyanine Green for All Nervous System Tumors other 1 recruiting NCT04516720
Creation of a Clinical Database on Primary Nervous System Tumors No drug interventions Not Available Not Available recruiting NCT02687386
A Study of Intravenous EEDVsMit in Children With Recurrent / Refractory Solid or CNS Tumours Expressing EGFR treatment 1 terminated NCT02221986
Interdisciplinary Rehabilitation of Patients With Glioma During Anti-cancer Treatment No drug interventions treatment Not Available completed NCT02797366
Proton Radiotherapy for Primary Central Nervous System Tumours in Adults No drug interventions treatment 2 recruiting NCT00100802
Radiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas treatment 2 completed NCT03834961
Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia treatment 2 active_not_recruiting NCT01217437
Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors treatment 2 completed NCT04692324
Cerebrospinal Fluid Biomarkers for Brain Tumors No drug interventions Not Available Not Available recruiting NCT01941758
High-Dose Trivalent Influenza Vaccine in Inducing Immune Response Patients With Central Nervous System Tumors basic_science 1 completed NCT01474174
Trivalent Influenza Vaccine in Preventing Flu in Patients With Central Nervous System Tumors Not Available Not Available completed NCT03012620
Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types treatment 2 completed NCT01538095
Trebananib in Treating Younger Patients With Relapsed or Refractory Solid Tumors, Including Central Nervous System Tumors treatment 1 completed NCT00898755
Collecting and Storing Tissue From Young Patients With Cancer No drug interventions Not Available Not Available active_not_recruiting NCT05169151
Mobility and Physical Activity in Adolescent and Young Adult Cancer Patients or Survivors at Risk for Cardiovascular Morbidity and Frailty, The MOBILE AYA Study No drug interventions Not Available Not Available withdrawn NCT04988009
Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology No drug interventions Not Available Not Available recruiting NCT03270059
Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System diagnostic 2 recruiting NCT03071913
Blood Brain Barrier Differences in Patients With Brain Tumors Undergoing Surgery No drug interventions Not Available Not Available completed NCT04539574
An Investigational Scan (7T MRI) for the Imaging of Central Nervous System Tumors No drug interventions diagnostic Not Available active_not_recruiting NCT02867592
Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors treatment 2 active_not_recruiting NCT02402244
Project: Every Child for Younger Patients With Cancer No drug interventions Not Available Not Available recruiting NCT02100891
Phase 2 STIR Trial: Haploidentical Transplant and Donor Natural Killer Cells for Solid Tumors treatment 2 completed NCT04081701
68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. No drug interventions diagnostic 4 recruiting NCT01505569
Auto Transplant for High Risk or Relapsed Solid or CNS Tumors other Not Available completed NCT02650401
Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options treatment 1 / 2 active_not_recruiting NCT01032200
Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors supportive_care 2 completed NCT05641636
Cardiovascular Disorders and Risk Factors in Childhood Cranial and Craniospinal Tumors Survivors No drug interventions Not Available Not Available completed NCT00633958
A Pilot Study of 18F-FLT in Pediatric Patients With Central Nervous System (CNS) Tumors diagnostic 1 terminated NCT03332030
Stem Cells in NF1 Patients With Tumors of the Central Nervous System No drug interventions Not Available Not Available withdrawn