Gastroenteropancreatic Neuroendocrine Tumors (DBCOND0063370)

Identifiers

Synonyms
Gastro-entero-pancreatic Neuroendocrine Tumor / Gastro-entero Pancreatic Neuroendocrine Tumors / Gastro Entero Pancreatic Neuroendocrine Tumors / Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) / Neuroendocrine Gastroenteropancreatic Tumour / Gastro-entero-pancreatic Neuroendocrine Tumors / GEP-NET / Gastro-enteropancreatic Neuroendocrine Tumor / Gastro-Entero-Pancreatic Tumors (GEPs) / Gastroenteropancreatic Neuroendocrine Tumors (GEP-NET) / Neuroendocrine Tumors,Gastroenteropancreatic / Gastroenteral-Pancreatic Neuroendocrine Tumors / Gastroenteropancreatic Neuroendocrine Tumours / Gastroenteropancreatic Neuroendocrine Tumor / Gastroenteropancreatic Neuroendocrine Tumour (GEP-NET) / Gastroenteropancreatic Neuroendocrine Tumor Disease / Gep Net / Gastroenteropancreatic neuroendocrine tumour disease

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Lutetium Lu 177 dotatate
A radiolabeled somatostatin analog used to treat somatostatin receptor positive gastroenteropancreatic neuroendocrine tumors.
Pentetreotide
A somatostatin receptor inhibitor, available in a kit with Indium-111, used as a contrast agent in the visualization of somatostatin receptor-positive neuroendocrine tumours.
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06344832
SSTR PET/CT for Preoperative N Stage Evaluation in GEP-NETsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04282083
Protocol ITANET - RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02736500
Peptide Receptor Radionuclide Therapy With 177Lu-Dotatate Associated With Metronomic Capecitabine In Patients Affected By Aggressive Gastro-Etero-Pancreatic Neuroendocrine Tumorstreatment1 / 2unknown_status
NCT04837885
Intra-arterial Hepatic (IAH) Infusion of Radiolabelled Somatostatin Analogs in GEP-NET Patients With Dominant Liver Metastasestreatment2recruiting
NCT02736448
177Lutethium - Peptide Receptor Radionuclide Therapy (Lu-PRRT) Plus Capecitabine Versus Lu-PRRT in FDG Positive, Gastro-entero-pancreatic Neuroendocrine Tumorstreatment2unknown_status
NCT05364944
A Study to Assess the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Debio 4126 in Participants With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)treatment1active_not_recruiting
NCT05385861
Nal-IRI (ONIVYDE® ) and Carboplatin in Patients With Advanced or Metastatic GEP-NETtreatment1 / 2enrolling_by_invitation
NCT06356467
Influence of Tumour and Patient's Related Factors on the Response to Medical Treatments in Well Differentiated GEP-NENsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05709171
Dual 64Cu-DOTATATE and 18F-FDG PET/CT Imaging of Patients With Neuroendocrine Neoplasmsdiagnostic2enrolling_by_invitation
NCT05477576
Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapytreatment3recruiting
NCT06253897
A Study to Understand Participant's Experiences in Gastro-enteropancreatic Neuroendocrine Tumors (GEP-NETs) and AcromegalyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03972488
Study to Evaluate the Efficacy and Safety of Lutathera in Patients With Grade 2 and Grade 3 Advanced GEP-NETtreatment3active_not_recruiting
NCT05050942
A Trial to Assess Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With GEP-NETtreatment3active_not_recruiting
NCT01423734
The Reproducibility Of Diffusion Weighted Magnetic Resonance Imaging For Neuroendocrine Tumor Liver MetastasesNo drug interventionsNot AvailableNot Availablecompleted
NCT03600233
Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumorstreatment2active_not_recruiting
NCT03475953
A Phase I/II Study of Regorafenib Plus Avelumab in Solid Tumorstreatment1 / 2recruiting
NCT03863106
The Lyon Real World Evidence in Metastatic NeuroEndocrine TumoursNo drug interventionsNot AvailableNot Availableunknown_status
NCT03220217
To Evaluate the Optimal Dose of 68Ga-OPS202 as a PET (Positron Emission Tomography) Imaging Agent in Subjects With Gastroenteropancreatic Neuroendocrine Tumour (GEP-NET)diagnostic2completed
NCT02779257
Pasireotide Treatment for Neuroendocrine Tumortreatment4withdrawn
NCT04614766
A Clinical Trial Evaluating the Safety of Combining Lutathera(R) and Azedra(R) to Treat Mid-gut Neuroendocrine Tumorstreatment1 / 2withdrawn
NCT03042780
FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomastreatment2terminated
NCT02150408
Evaluation of PET-CT Using Somatostatin Agonists Labeled With Gallium68 in Neuroendocrine TumorsNo drug interventionsdiagnosticNot Availablecompleted
NCT05048901
Cabozantinib and Lanreotide as Treatment for Gastroenteropancreatic Neuroendocrine Tumorstreatment1 / 2recruiting
NCT02788565
Quality of Life, Treatment Experience and Cost of Treatment With Somatostatin Analogues in Patients With Gastroenteropancreatic Neuroendocrine TumoursNo drug interventionsNot AvailableNot Availablecompleted
NCT04852679
Study to Assess the Efficacy and Safety of Lanreotide Autogel® in Chinese Participants With GEP-NETstreatment3completed
NCT04609592
Study of PRRT in Metastatic, World Health Organization (WHO) Grade 1 or 2, SSTR Positive, GEP-NET Who Are Candidates for Cytoreductive Surgerytreatment1recruiting
NCT06256705
Multi-modal Characterisation of Gastroenteropancreatic Neuroendocrine Tumours (GEP-NETs) Treated With Targeted Radionuclide Therapy (TRT): Prospective Interventional Multicentre National CohortNo drug interventionsotherNot Availablerecruiting
NCT05262556
NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomastreatment1active_not_recruiting
NCT04986085
Nutrition in Gastroenteropancreatic Neuroendocrine TumorNo drug interventionsNot AvailableNot Availablecompleted
NCT06155318
68Ga-DOTATOC PET for the Evaluation of Gastroenteropancreatic Neuroendocrine TumoursNo drug interventionsNot AvailableNot Availablerecruiting
NCT05701241
Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtientstreatment4recruiting
NCT02611024
Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumorstreatment1 / 2recruiting
NCT03980925
Platinum-doublet Chemotherapy and Nivolumab for the Treatment of Subjects With Neuroendocrine Neoplasms (NENs) of the Gastroenteropancreatic (GEP) Tract or of Unknown (UK) Origin.treatment2active_not_recruiting
NCT04727723
Italian Prospective Observational Study Assessing the Effectiveness and Outcomes Associated With Lutathera Treatment in GEP-NETsNot AvailableNot Availableactive_not_recruiting
NCT03017690
Lanreotide and Octreotide Long Acting Release (LAR) for Patients With Advanced Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)No drug interventionsNot AvailableNot Availablecompleted
NCT01994213
A Study of Famitinib in Patients With Advanced or Metastatic Gastroenteropancreatic Neuroendocrine Tumortreatment2terminated
NCT05987176
Comparison of Adjuvant Treatment With 177Lu-DOTATATE to Best Supportive Care in Patients After Resection of Neuroendocrine Liver Metastasestreatment2recruiting
NCT04915144
177Lu-DOTATOC for the Treatment of Patients With Somatostatin Receptor Positive NETstreatment2withdrawn
NCT02948946
Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT05064150
Neuroendocrine Tumors - Patient Reported OutcomesNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT05359146
Combined Beta- Plus Auger Electron Therapy Using a Novel Somatostatin Receptor Subtype 2 Antagonist Labelled With Terbium-161 (161Tb-DOTA-LM3)basic_science0recruiting
NCT04524442
Post-Authorization Safety Study (PASS) of LysaKare® in Adult Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) Patientsother4completed
NCT03043664
Study of Pembrolizumab With Lanreotide Depot for Gastroenteropancreatic Neuroendocrine Tumorstreatment1 / 2completed
NCT02078843
Diagnostic Accuracy of Gallium-68-DOTATATE PET/CT Compared to Indium-111-pentetreotide Scintigraphy (SPECT/CT) for Gastroenteropancreatic Neuroendocrine Tumorsdiagnostic1 / 2terminated
NCT02630654
Study For Evaluating The Value Of A Multi Biomarker Approach In Metastatic GEP NETsNo drug interventionsNot AvailableNot Availablecompleted
NCT04711135
Study to Evaluate Safety and Dosimetry of Lutathera in Adolescent Patients With GEP-NETs and PPGLstreatment2active_not_recruiting
NCT01842165
177Lutetium-octreotate Treatment Prediction Using Multimodality Imaging in Refractory NETstreatment3completed
NCT02730104
Community-based Neuroendocrine Tumor (NET) Research StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02162446
68Ga-OPS202 Study for Diagnostic Imaging of GEP NETdiagnostic1 / 2completed
NCT02608203
[68 Ga]-DOTANOC PET/CT in GEP-NETsNo drug interventionsdiagnostic2 / 3completed
NCT02231762
Combination of Lanreotide Autogel 120mg and Temozolomide in Progressive GEP-NETtreatment2completed
NCT06402695
Observational Study on GEP-and Pulm-NET Treated at FPGNo drug interventionsNot AvailableNot Availablerecruiting
NCT05448157
68Ga-DOTATOC Radio-Guided Surgery With β-Probe in GEP-NETNo drug interventionsNot AvailableNot Availableactive_not_recruiting