Acute Tubulo-Interstitial Nephritis (DBCOND0129204)

Identifiers

Synonyms
Pyelonephritis acute / Acute Pyelonephritis / Acute Pyelonephritis(APN) / Acute nephrosis / Acute tubulointerstitial nephritis / Acute tubulo-interstitial nephritis / Acute infectious interstitial nephritis / Pyelonephritis acute NOS / Acute pyelonephritis (disorder) / Acute interstitial nephritis / Interstitial nephritis acute / Nephritis interstitial acute / Acute tubulointerstitial nephritis (disorder) / Pyelitis, acute / Acute pyelitis (disorder) / Acute pyelitis / Acute bacterial tubulointerstitial nephritis (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Albumin human
A purified form of human serum albumin used to replace lost albumin in patients with hypoalbuminemia, to treat hypovolemia and ascites, and as a part of some diagnostic imaging kits.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04376216
Prednisolone Treatment in Acute Interstitial Nephritistreatment4recruiting
NCT02192580
Oral Omega-3 for Reduction of Kidney Scar Due to Pyelonephritis in Childrenprevention3unknown_status
NCT02007889
L-carnitine on the Prevention of Renal Scarring in Acute Pyelonephritisprevention3unknown_status
NCT04882085
Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adultstreatment4completed
NCT06059846
A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)treatment3recruiting
NCT01928433
Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritistreatment2completed
NCT02034851
Dexamethasone Administration in 1st Episode of Febrile Urinary Tract InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT04654507
Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Childrenprevention3recruiting
NCT04979806
Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)treatment3recruiting
NCT03757234
IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritistreatment2completed
NCT03788967
Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)treatment3completed
NCT02168946
Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adultstreatment3completed
NCT03630081
Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)treatment3not_yet_recruiting
NCT02537847
Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Colitreatment2unknown_status
NCT05674032
Bacterial Metallophores in the Diagnosis of Acute PyelonephritisNo drug interventionsNot AvailableNot Availablerecruiting
NCT01096849
A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP)treatment2completed
NCT04686318
Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute PyelonephritisNo drug interventionsNot AvailableNot Availablecompleted
NCT05060419
Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infectionstreatment2unknown_status
NCT04682834
Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract InfectionNot AvailableNot Availableno_longer_available
NCT03477422
CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteriatreatment3completed
NCT03840148
Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infectionstreatment3completed
NCT02420366
Study of Cases of Serious Infections Due to Carbapenem-Resistant EnterobacteriaceaeNo drug interventionsNot AvailableNot Availablecompleted
NCT02486627
A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)treatment3completed
NCT02166476
Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and APtreatment3completed
NCT02753946
Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infectionstreatment2 / 3completed
NCT03445195
Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infectionstreatment2completed
NCT04667195
Clinical Characteristics of Acutely Hospitalized Adults With Acute PyelonephritisNo drug interventionsNot AvailableNot Availablecompleted
NCT06141395
NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial IdentificationNo drug interventionsNot AvailableNot Availablecompleted
NCT05905055
P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacteralestreatment3recruiting
NCT05887908
Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritistreatment3recruiting
NCT03959163
The Validity of the Quick Renal MRI in Pediatric Kidney DiseaseNo drug interventionsdiagnosticNot Availablerecruiting
NCT06127160
Patient-Directed Antimicrobial Duration in Acute Uncomplicated Pyelonephritistreatment4recruiting
NCT04651244
Diagnostic Imaging of Acute PyelonephritisNo drug interventionsNot AvailableNot Availablecompleted
NCT03179384
Impact on the Intestinal Microbiota of Treatment With Ceftriaxone in Women's Acute Community Pyelonephritisother4completed
NCT04700787
Safety, Tolerability, and Pharmacokinetics of Sulopenem in Adolescentstreatment1withdrawn
NCT04594161
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by UrolithiasisNo drug interventionsotherNot Availablecompleted
NCT05544565
3-day IV Antibiotic Treatment Versus 3-day IV Followed by 7-day Oral Antibiotic Treatment for AP in ChildrenNo drug interventionstreatment4suspended
NCT05597540
Efficacy of 7 Days Versus 14 Days of Antibiotic Therapy for Acute Pyelonephritis in Kidney Transplant Recipients, a Multicentre Randomized Non-inferiority Trial.No drug interventionstreatment3recruiting