Prostaglandins, Synthetic

Name
Prostaglandins, Synthetic
Accession Number
DBCAT000677
Description

Compounds obtained by chemical synthesis that are analogs or derivatives of naturally occurring prostaglandins and that have similar activity.

ATC Classification
Drugs
DrugDrug Description
TravoprostA prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension.
BimatoprostA prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension.
LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
UnoprostoneA prostaglandin analogue used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension who are clinically unresponsive to other ocular antihypertensive agents.
TafluprostAn ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma.
Carboprost tromethamineA prostaglandin used to treat postpartum uterine hemorrhage due to atony when other methods of management have not been effective.
MisoprostolA prostaglandin E1 analogue used to reduce the risk of NSAID-induced gastric ulcers.
IloprostA synthetic prostacyclin analog indicated to treat pulmonary arterial hypertension (PAH).
FenprostaleneNot Annotated
LuprostiolNot Annotated
ProstaleneAnalog of prostaglandin F2 alpha.
CloprostenolNot Annotated
FluprostenolNot Annotated
Latanoprostene bunodA prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma.
EnprostilNot Annotated
AlprostadilA medication used to treat erectile dysfunction.
DinoprostoneA prostaglandin used to induce labor or abortion as well as to treat nonmetastatic gestational trophoblastic disease.
NetarsudilA rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension.
Drugs & Drug Targets
DrugTargetType
TravoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin F2-alpha receptortarget
BimatoprostProstaglandin E2 receptor EP1 subtypetarget
BimatoprostProstaglandin E2 receptor EP3 subtypetarget
BimatoprostCytochrome P450 3A4enzyme
BimatoprostCytochrome P450 3A5enzyme
LatanoprostProstaglandin F2-alpha receptortarget
LatanoprostSolute carrier organic anion transporter family member 2A1transporter
LatanoprostSolute carrier family 22 member 6transporter
LatanoprostSolute carrier family 22 member 8transporter
LatanoprostCorneal esterasesenzyme
TafluprostProstaglandin F2-alpha receptortarget
TafluprostProstaglandin G/H synthase 2enzyme
Carboprost tromethamineProstaglandin E2 receptor EP1 subtypetarget
MisoprostolProstaglandin E2 receptor EP2 subtypetarget
MisoprostolProstaglandin E2 receptor EP3 subtypetarget
MisoprostolProstaglandin E2 receptor EP4 subtypetarget
MisoprostolProstaglandin E2 receptor EP1 subtypetarget
IloprostProstacyclin receptortarget
IloprostTissue-type plasminogen activatortarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IloprostSolute carrier organic anion transporter family member 2B1transporter
IloprostSolute carrier organic anion transporter family member 2A1transporter
IloprostSolute carrier organic anion transporter family member 3A1transporter
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IloprostcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
IloprostProstaglandin E2 receptor EP1 subtypetarget
IloprostProstaglandin D2 receptor 2target
LuprostiolAndrogen receptortarget
Latanoprostene bunodProstaglandin F2-alpha receptortarget
Latanoprostene bunodSolute carrier organic anion transporter family member 2B1transporter
AlprostadilProstaglandin E2 receptor EP2 subtypetarget
AlprostadilProstaglandin E2 receptor EP1 subtypetarget
AlprostadilMultidrug resistance-associated protein 5transporter
AlprostadilSolute carrier organic anion transporter family member 2B1transporter
AlprostadilSolute carrier organic anion transporter family member 3A1transporter
AlprostadilMultidrug resistance-associated protein 4transporter
AlprostadilSolute carrier organic anion transporter family member 2A1transporter
AlprostadilProstaglandin D2 receptor 2target
AlprostadilSolute carrier family 22 member 6transporter
DinoprostoneProstaglandin E2 receptor EP2 subtypetarget
DinoprostoneProstaglandin E2 receptor EP1 subtypetarget
DinoprostoneProstaglandin E2 receptor EP4 subtypetarget
DinoprostoneProstaglandin E2 receptor EP3 subtypetarget
DinoprostoneSolute carrier family 22 member 2transporter
DinoprostoneMultidrug resistance-associated protein 5transporter
DinoprostoneSolute carrier family 22 member 6transporter
DinoprostoneSolute carrier family 22 member 8transporter
DinoprostoneSolute carrier family 22 member 11transporter
DinoprostoneSolute carrier family 22 member 7transporter
DinoprostoneMultidrug resistance-associated protein 4transporter
DinoprostoneSolute carrier organic anion transporter family member 2B1transporter
DinoprostoneSolute carrier organic anion transporter family member 1A2transporter
DinoprostoneOrganic solute transporter subunit alphatransporter
DinoprostoneOrganic solute transporter subunit betatransporter
DinoprostoneSolute carrier organic anion transporter family member 2A1transporter
DinoprostoneSolute carrier organic anion transporter family member 4A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1C1transporter
DinoprostoneSolute carrier organic anion transporter family member 3A1transporter
DinoprostoneSolute carrier organic anion transporter family member 1B1transporter
DinoprostoneProstaglandin D2 receptor 2target
NetarsudilRho-associated protein kinase 1target
NetarsudilRho-associated protein kinase 2target
NetarsudilSodium-dependent noradrenaline transportertarget