Autism Disorder

Also known as: Autism Spectrum Disorders / Autistic Spectrum Disorder (ASD) / Autism / Autism Spectrum Disorder / Autism-Spectrum Disorder / Autistic Disorders Spectrum / Autism Spectrum Conditions/Disorders / Autistic Spectrum Disorders / Autistic Spectrum Disorder / Autism Spectrum Disorder (ASD) / Autistic Disorder / Childhood autism / Autistic disorder of childhood onset (disorder) / Kanner's syndrome / Infantile autism NOS (disorder) / Childhood autism [Ambiguous] / Infantile autism / Early infantile autism / Autism infantile / Infantile autism (disorder) / Autistic disorder (disorder) / Autistic thinking (finding)

Drug	Drug Name	Drug Description
DB01238	Aripiprazole	An atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
DB00734	Risperidone	A second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.

Drug	Drug Name	Target	Type
DB01238	Aripiprazole	Dopamine D2 receptor	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 1A	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 2A	target
DB01238	Aripiprazole	Cytochrome P450 3A4	enzyme
DB01238	Aripiprazole	Cytochrome P450 2D6	enzyme
DB01238	Aripiprazole	5-hydroxytryptamine receptor 1B	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 1D	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 1E	target
DB01238	Aripiprazole	Dopamine D1 receptor	target
DB01238	Aripiprazole	Dopamine D5 receptor	target
DB01238	Aripiprazole	Dopamine D3 receptor	target
DB01238	Aripiprazole	Dopamine D4 receptor	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 2C	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 3A	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 6	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 7	target
DB01238	Aripiprazole	Histamine H1 receptor	target
DB01238	Aripiprazole	Alpha-1A adrenergic receptor	target
DB01238	Aripiprazole	Alpha-1B adrenergic receptor	target
DB01238	Aripiprazole	Alpha-2A adrenergic receptor	target
DB01238	Aripiprazole	Alpha-2B adrenergic receptor	target
DB01238	Aripiprazole	Alpha-2C adrenergic receptor	target
DB01238	Aripiprazole	Cytochrome P450 3A5	enzyme
DB01238	Aripiprazole	Cytochrome P450 3A7	enzyme
DB01238	Aripiprazole	Serum albumin	carrier
DB01238	Aripiprazole	5-hydroxytryptamine receptor 2B	target
DB01238	Aripiprazole	5-hydroxytryptamine receptor 5A	target
DB01238	Aripiprazole	Beta-1 adrenergic receptor	target
DB01238	Aripiprazole	Beta-2 adrenergic receptor	target
DB01238	Aripiprazole	Histamine H2 receptor	target
DB01238	Aripiprazole	Histamine H3 receptor	target
DB01238	Aripiprazole	Histamine H4 receptor	target
DB01238	Aripiprazole	Muscarinic acetylcholine receptor M1	target
DB01238	Aripiprazole	Muscarinic acetylcholine receptor M2	target
DB01238	Aripiprazole	Muscarinic acetylcholine receptor M3	target
DB01238	Aripiprazole	Muscarinic acetylcholine receptor M4	target
DB01238	Aripiprazole	Muscarinic acetylcholine receptor M5	target
DB01238	Aripiprazole	Kappa-type opioid receptor	target
DB01238	Aripiprazole	Mu-type opioid receptor	target
DB01238	Aripiprazole	Delta-type opioid receptor	target
DB01238	Aripiprazole	Glutamate (NMDA) receptor	target
DB01238	Aripiprazole	Sodium-dependent dopamine transporter	target
DB01238	Aripiprazole	Sodium-dependent serotonin transporter	target
DB01238	Aripiprazole	P-glycoprotein 1	transporter
DB01238	Aripiprazole	ATP-binding cassette sub-family G member 2	transporter
DB00734	Risperidone	Cytochrome P450 2D6	enzyme
DB00734	Risperidone	Cytochrome P450 3A4	enzyme
DB00734	Risperidone	P-glycoprotein 1	transporter
DB00734	Risperidone	Serum albumin	carrier
DB00734	Risperidone	Alpha-1-acid glycoprotein 1	carrier
DB00734	Risperidone	5-hydroxytryptamine receptor 2A	target
DB00734	Risperidone	Dopamine D2 receptor	target
DB00734	Risperidone	Alpha-1B adrenergic receptor	target
DB00734	Risperidone	Alpha-2B adrenergic receptor	target
DB00734	Risperidone	Alpha-1A adrenergic receptor	target
DB00734	Risperidone	Alpha-2C adrenergic receptor	target
DB00734	Risperidone	Histamine H1 receptor	target
DB00734	Risperidone	5-hydroxytryptamine receptor 2C	target
DB00734	Risperidone	5-hydroxytryptamine receptor 1D	target
DB00734	Risperidone	5-hydroxytryptamine receptor 1A	target
DB00734	Risperidone	5-hydroxytryptamine receptor 7	target
DB00734	Risperidone	D(2L) dopamine receptor	target
DB00734	Risperidone	Dopamine D1 receptor	target

Drug	Drug Name	Phase	Status	Count
DB08891	Arbaclofen	0	Completed	1
DB00996	Gabapentin	0	Completed	1
DB03323	Maltose	0	Completed	1
DB01043	Memantine	0	Completed	1
DB00422	Methylphenidate	0	Completed	1
DB00571	Propranolol	0	Completed	1
DB00740	Riluzole	0	Completed	1
DB11132	Silicon dioxide	0	Completed	1
DB00755	Tretinoin	0	Recruiting	1
DB00659	Acamprosate	1	Completed	1
DB08891	Arbaclofen	1	Terminated	1
DB00126	Ascorbic acid	1	Terminated	1
DB14823	Balovaptan	1	Completed	1
DB14823	Balovaptan	1	Terminated	1
DB14823	Balovaptan	1	Withdrawn	1
DB09128	Brexpiprazole	1	Completed	1
DB09061	Cannabidiol	1	Recruiting	1
DB06016	Cariprazine	1	Completed	1
DB00215	Citalopram	1	Completed	1
DB00736	Esomeprazole	1	Completed	1
DB13134	Fluorine F-18	1	Completed	1
DB05708	GTS-21	1	Terminated	1
DB01221	Ketamine	1	Completed	1
DB00583	Levocarnitine	1	Unknown Status	1
DB00166	Lipoic acid	1	Unknown Status	1
DB08815	Lurasidone	1	Completed	1
DB00657	Mecamylamine	1	Completed	1
DB01065	Melatonin	1	Completed	1
DB00683	Midazolam	1	Completed	1
DB01017	Minocycline	1	Completed	1
DB01017	Minocycline	1	Suspended	1
DB00184	Nicotine	1	Completed	1
DB00043	Omalizumab	1	Withdrawn	1
DB00107	Oxytocin	1	Completed	6
DB00107	Oxytocin	1	Recruiting	1
DB00107	Oxytocin	1	Terminated	1
DB00107	Oxytocin	1	Withdrawn	1
DB12721	RO-5028442	1	Completed	1
DB17081	RO6953958	1	Completed	1
DB00734	Risperidone	1	Active Not Recruiting	1
DB09071	Tasimelteon	1	Unknown Status	1
DB00512	Vancomycin	1	Enrolling by Invitation	1
DB00067	Vasopressin	1	Completed	1
DB01593	Zinc	1	Terminated	1
DB00126	Ascorbic acid	1 / 2	Completed	1
DB00490	Buspirone	1 / 2	Completed	1
DB14089	Dimercaptosuccinic acid	1 / 2	Completed	1
DB00843	Donepezil	1 / 2	Completed	1
DB15726	Human Umbilical Cord Mesenchymal Stem Cells	1 / 2	Completed	1
DB12583	Maltodextrin	1 / 2	Completed	1
DB12583	Maltodextrin	1 / 2	Recruiting	1
DB00338	Omeprazole	1 / 2	Completed	1
DB00107	Oxytocin	1 / 2	Completed	1
DB09287	Polyethylene glycol	1 / 2	Completed	1
DB00761	Potassium chloride	1 / 2	Completed	1
DB14482	Sodium ascorbate	1 / 2	Completed	1
DB09153	Sodium chloride	1 / 2	Completed	1
DB09472	Sodium sulfate	1 / 2	Completed	1
DB00566	Succimer	1 / 2	Completed	1
DB12422	Sulforaphane	1 / 2	Completed	1
DB04786	Suramin	1 / 2	Completed	1
DB00512	Vancomycin	1 / 2	Completed	1
DB13994	AZD-7325	2	Completed	1
DB00659	Acamprosate	2	Completed	1
DB06151	Acetylcysteine	2	Completed	2
DB06151	Acetylcysteine	2	Recruiting	1
DB00182	Amphetamine	2	Terminated	1
DB08891	Arbaclofen	2	Active Not Recruiting	1
DB08891	Arbaclofen	2	Completed	3
DB08891	Arbaclofen	2	Terminated	1
DB01238	Aripiprazole	2	Completed	4
DB00126	Ascorbic acid	2	Active Not Recruiting	1
DB06698	Betahistine	2	Completed	1
DB00887	Bumetanide	2	Completed	1
DB00887	Bumetanide	2	Withdrawn	1
DB00490	Buspirone	2	Not Yet Recruiting	1
DB00490	Buspirone	2	Withdrawn	1
DB03568	Butyric Acid	2	Completed	1
DB06247	CX516	2	Completed	1
DB01373	Calcium	2	Active Not Recruiting	2
DB09061	Cannabidiol	2	Active Not Recruiting	1
DB09061	Cannabidiol	2	Recruiting	2
DB14050	Cannabidivarin	2	Recruiting	1
DB14050	Cannabidivarin	2	Terminated	1
DB00169	Cholecalciferol	2	Completed	2
DB00215	Citalopram	2	Completed	1
DB00575	Clonidine	2	Withdrawn	1
DB14322	Coconut oil	2	Completed	1
DB00151	Cysteine	2	Completed	2
DB00633	Dexmedetomidine	2	Suspended	1
DB00514	Dextromethorphan	2	Completed	1
DB01075	Diphenhydramine	2	Not Yet Recruiting	1
DB00843	Donepezil	2	Completed	1
DB00843	Donepezil	2	Terminated	2
DB00736	Esomeprazole	2	Not Yet Recruiting	1
DB00736	Esomeprazole	2	Recruiting	1
DB00736	Esomeprazole	2	Suspended	1
DB01590	Everolimus	2	Completed	1
DB13257	Ferrous sulfate anhydrous	2	Completed	1
DB00472	Fluoxetine	2	Completed	1
DB00472	Fluoxetine	2	Withdrawn	1
DB15436	Glucoraphanin	2	Completed	1
DB15726	Human Umbilical Cord Mesenchymal Stem Cells	2	Active Not Recruiting	1
DB15173	JNJ-42165279	2	Completed	1
DB01221	Ketamine	2	Suspended	1
DB00480	Lenalidomide	2	Completed	1
DB00650	Leucovorin	2	Active Not Recruiting	3
DB00650	Leucovorin	2	Completed	1
DB00650	Leucovorin	2	Terminated	1
DB00650	Leucovorin	2	Unknown Status	1
DB08815	Lurasidone	2	Completed	1
DB01277	Mecasermin	2	Recruiting	1
DB14009	Medical Cannabis	2	Recruiting	1
DB14009	Medical Cannabis	2	Withdrawn	1
DB01065	Melatonin	2	Terminated	1
DB01043	Memantine	2	Completed	5
DB01043	Memantine	2	Terminated	1
DB00334	Olanzapine	2	Completed	1
DB09567	Olive oil	2	Withdrawn	1
DB11133	Omega-3 fatty acids	2	Completed	1
DB11133	Omega-3 fatty acids	2	Terminated	1
DB00107	Oxytocin	2	Completed	13
DB00107	Oxytocin	2	Terminated	1
DB00107	Oxytocin	2	Withdrawn	1
DB01132	Pioglitazone	2	Completed	1
DB09287	Polyethylene glycol	2	Active Not Recruiting	2
DB00761	Potassium chloride	2	Active Not Recruiting	1
DB02789	Pregnenolone	2	Completed	1
DB02789	Pregnenolone	2	Recruiting	1
DB00571	Propranolol	2	Recruiting	1
DB00165	Pyridoxine	2	Unknown Status	1
DB00908	Quinidine	2	Completed	1
DB12721	RO-5028442	2	Completed	1
DB00740	Riluzole	2	Completed	2
DB00734	Risperidone	2	Completed	2
DB00360	Sapropterin	2	Completed	1
DB01104	Sertraline	2	Active Not Recruiting	1
DB01104	Sertraline	2	Completed	1
DB00877	Sirolimus	2	Completed	1
DB14482	Sodium ascorbate	2	Active Not Recruiting	1
DB09153	Sodium chloride	2	Active Not Recruiting	1
DB09472	Sodium sulfate	2	Active Not Recruiting	1
DB00052	Somatotropin	2	Enrolling by Invitation	1
DB12422	Sulforaphane	2	Active Not Recruiting	1
DB12422	Sulforaphane	2	Completed	2
DB09034	Suvorexant	2	Not Yet Recruiting	1
DB12129	Tideglusib	2	Completed	1
DB00313	Valproic acid	2	Completed	1
DB00313	Valproic acid	2	Withdrawn	2
DB00512	Vancomycin	2	Active Not Recruiting	2
DB00067	Vasopressin	2	Completed	1
DB11917	Vatiquinone	2	Withdrawn	1
DB11094	Vitamin D	2	Completed	1
DB00246	Ziprasidone	2	Completed	1
DB00425	Zolpidem	2	Not Yet Recruiting	1
DB06151	Acetylcysteine	2 / 3	Enrolling by Invitation	1
DB00490	Buspirone	2 / 3	Completed	1
DB09061	Cannabidiol	2 / 3	Active Not Recruiting	1
DB00115	Cyanocobalamin	2 / 3	Completed	1
DB00151	Cysteine	2 / 3	Recruiting	1
DB00514	Dextromethorphan	2 / 3	Withdrawn	1
DB00650	Leucovorin	2 / 3	Completed	1
DB03614	Mecobalamin	2 / 3	Completed	2
DB14009	Medical Cannabis	2 / 3	Not Yet Recruiting	1
DB01065	Melatonin	2 / 3	Completed	1
DB00422	Methylphenidate	2 / 3	Completed	1
DB00334	Olanzapine	2 / 3	Completed	1
DB00107	Oxytocin	2 / 3	Terminated	1
DB00734	Risperidone	2 / 3	Completed	1
DB00360	Sapropterin	2 / 3	Completed	1
DB00067	Vasopressin	2 / 3	Recruiting	1
DB11094	Vitamin D	2 / 3	Completed	1
DB00321	Amitriptyline	3	Not Yet Recruiting	1
DB08891	Arbaclofen	3	Terminated	1
DB01238	Aripiprazole	3	Completed	7
DB00289	Atomoxetine	3	Completed	1
DB14823	Balovaptan	3	Terminated	1
DB00887	Bumetanide	3	Recruiting	1
DB00887	Bumetanide	3	Terminated	2
DB06016	Cariprazine	3	Recruiting	2
DB04272	Citric acid	3	Completed	1
DB00260	Cycloserine	3	Completed	3
DB00472	Fluoxetine	3	Completed	1
DB00472	Fluoxetine	3	Terminated	1
DB00176	Fluvoxamine	3	Completed	1
DB00674	Galantamine	3	Completed	1
DB14509	Lithium carbonate	3	Recruiting	1
DB08815	Lurasidone	3	Completed	2
DB14009	Medical Cannabis	3	Active Not Recruiting	1
DB01065	Melatonin	3	Withdrawn	1
DB01043	Memantine	3	Completed	1
DB01043	Memantine	3	Recruiting	1
DB00331	Metformin	3	Completed	1
DB00422	Methylphenidate	3	Completed	1
DB00370	Mirtazapine	3	Completed	1
DB00107	Oxytocin	3	Active Not Recruiting	1
DB00107	Oxytocin	3	Completed	1
DB01267	Paliperidone	3	Completed	1
DB00734	Risperidone	3	Completed	2
DB06369	Secretin human	3	Completed	2
DB06369	Secretin human	3	Terminated	1
DB01104	Sertraline	3	Completed	1
DB09071	Tasimelteon	3	Recruiting	1
DB00313	Valproic acid	3	Unknown Status	1
DB06151	Acetylcysteine	4	Recruiting	1
DB01238	Aripiprazole	4	Completed	2
DB01238	Aripiprazole	4	Recruiting	1
DB01238	Aripiprazole	4	Unknown Status	1
DB00289	Atomoxetine	4	Completed	2
DB00490	Buspirone	4	Completed	1
DB00122	Choline	4	Unknown Status	1
DB00633	Dexmedetomidine	4	Unknown Status	1
DB00996	Gabapentin	4	Recruiting	1
DB00028	Human immunoglobulin G	4	Unknown Status	1
DB13178	Inositol	4	Recruiting	1
DB01255	Lisdexamfetamine	4	Recruiting	1
DB01043	Memantine	4	Completed	1
DB00331	Metformin	4	Completed	1
DB00422	Methylphenidate	4	Completed	2
DB04896	Milnacipran	4	Completed	1
DB01017	Minocycline	4	Completed	1
DB11133	Omega-3 fatty acids	4	Recruiting	1
DB00107	Oxytocin	4	Completed	1
DB00734	Risperidone	4	Completed	3
DB00734	Risperidone	4	Recruiting	1
DB06753	Triclofos	4	Unknown Status	1
DB00313	Valproic acid	4	Completed	1
DB06151	Acetylcysteine	Not Available	Completed	1
DB00802	Alfentanil	Not Available	Completed	1
DB00479	Amikacin	Not Available	Completed	1
DB00513	Aminocaproic acid	Not Available	Completed	1
DB08891	Arbaclofen	Not Available	Completed	1
DB01238	Aripiprazole	Not Available	Completed	2
DB00126	Ascorbic acid	Not Available	Completed	1
DB00181	Baclofen	Not Available	Withdrawn	1
DB09020	Bisacodyl	Not Available	Completed	1
DB00559	Bosentan	Not Available	Completed	1
DB00490	Buspirone	Not Available	Active Not Recruiting	1
DB09061	Cannabidiol	Not Available	Unknown Status	1
DB14050	Cannabidivarin	Not Available	Unknown Status	1
DB01413	Cefepime	Not Available	Completed	1
DB00369	Cidofovir	Not Available	Completed	1
DB00537	Ciprofloxacin	Not Available	Completed	1
DB00215	Citalopram	Not Available	Recruiting	1
DB00363	Clozapine	Not Available	Completed	1
DB00115	Cyanocobalamin	Not Available	Completed	1
DB00151	Cysteine	Not Available	Withdrawn	1
DB00633	Dexmedetomidine	Not Available	Completed	1
DB08917	Ferric carboxymaltose	Not Available	Recruiting	1
DB15617	Ferric derisomaltose	Not Available	Recruiting	1
DB11171	Ferric sulfate	Not Available	Recruiting	1
DB00196	Fluconazole	Not Available	Unknown Status	1
DB00472	Fluoxetine	Not Available	Completed	2
DB00828	Fosfomycin	Not Available	Completed	1
DB00143	Glutathione	Not Available	Completed	1
DB09462	Glycerin	Not Available	Completed	1
DB01018	Guanfacine	Not Available	Completed	1
DB00502	Haloperidol	Not Available	Completed	1
DB01592	Iron	Not Available	Recruiting	1
DB00598	Labetalol	Not Available	Completed	1
DB00227	Lovastatin	Not Available	Completed	1
DB08815	Lurasidone	Not Available	Completed	1
DB03614	Mecobalamin	Not Available	Completed	1
DB01065	Melatonin	Not Available	Not Yet Recruiting	1
DB01043	Memantine	Not Available	Terminated	1
DB01043	Memantine	Not Available	Withdrawn	1
DB00331	Metformin	Not Available	Not Yet Recruiting	1
DB00422	Methylphenidate	Not Available	Completed	1
DB00959	Methylprednisolone	Not Available	Completed	1
DB01618	Molindone	Not Available	Completed	1
DB00607	Nafcillin	Not Available	Completed	1
DB00704	Naltrexone	Not Available	Completed	1
DB01115	Nifedipine	Not Available	Completed	1
DB11133	Omega-3 fatty acids	Not Available	Completed	1
DB00776	Oxcarbazepine	Not Available	Completed	1
DB00497	Oxycodone	Not Available	Completed	1
DB00107	Oxytocin	Not Available	Active Not Recruiting	1
DB00107	Oxytocin	Not Available	Completed	1
DB00312	Pentobarbital	Not Available	Completed	1
DB00319	Piperacillin	Not Available	Completed	1
DB00571	Propranolol	Not Available	Completed	1
DB00571	Propranolol	Not Available	Withdrawn	1
DB11664	Psilocybin	Not Available	Recruiting	1
DB00734	Risperidone	Not Available	Completed	1
DB00728	Rocuronium	Not Available	Completed	1
DB00360	Sapropterin	Not Available	Completed	1
DB15889	Senna leaf	Not Available	Completed	1
DB00658	Sevelamer	Not Available	Completed	1
DB09072	Sodium oxybate	Not Available	Completed	1
DB00421	Spironolactone	Not Available	Completed	1
DB01606	Tazobactam	Not Available	Completed	1
DB09289	Tianeptine	Not Available	Recruiting	1
DB00684	Tobramycin	Not Available	Completed	1
DB00302	Tranexamic acid	Not Available	Completed	1
DB00512	Vancomycin	Not Available	Available	1
DB00512	Vancomycin	Not Available	Completed	1
DB01339	Vecuronium	Not Available	Completed	1
DB00682	Warfarin	Not Available	Completed	1
DB00246	Ziprasidone	Not Available	Completed	1
DB00425	Zolpidem	Not Available	Completed	1
DB01440	gamma-Hydroxybutyric acid	Not Available	Completed	1