Acetamides

Name
Acetamides
Accession Number
DBCAT000493
Description

Derivatives of acetamide that are used as solvents, as mild irritants, and in organic synthesis.

Drugs
DrugDrug Description
LinezolidAn oxazolidinone antibiotic used to treat infections by susceptible strains of aerobic Gram-positive bacteria.
Benzylpenicilloyl polylysineA penicillin derivative used to determine penicillin allergies.
PhenacemideUsed to control certain seizures in the treatment of epilepsy.
LevetiracetamA novel anticonvulsant agent used as an adjunct medication to manage partial onset, myoclonic, and generalized tonic-clonic seizures in patients with epilepsy.
CoelenteramideNot Available
NepafenacAn ophthalmic NSAID used for the symptomatic treatment of pain and inflammation associated with cataract surgery.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
PiracetamA nootropic cyclic GABA derivative used in myoclonus, sickle cell disease, alcohol dependence, and as a general cognitive enhancer.
CaroxazoneFor the treatment of depression.
Antineoplaston A10Antineoplaston A10 has been used in trials studying the treatment of Sarcoma, Lymphoma, Lung Cancer, Liver Cancer, and Kidney Cancer, among others.
AZD-5672Azd5672 has been used in trials studying the basic science and treatment of Pharmacokinetics, Renal Impairment, and Rheumatoid Arthritis.
EtiracetamEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
PF-00610355PF-00610355 has been used in trials studying the treatment of Lung Disease, Moxifloxacin, Pulmonary Disease, Asthma, Bronchial, and Bronchial Diseases, among others.
FigopitantFigopitant is under investigation in clinical trial NCT02209714 (Safety, Tolerability and Pharmacodynamics After Oral Administration of BIIF 1149 BS in Healthy Male Volunteers).
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
LorcainideNot Annotated
EpanololEpanolol is an beta blocker.
Oseltamivir acidNot Available
OseltamivirA neuraminidase inhibitor used in the prophylaxis and treatment of influenza.
TelaglenastatTelaglenastat is under investigation in clinical trial NCT02071862 (Study of the Glutaminase Inhibitor CB-839 in Solid Tumors).
LacosamideAn antiepileptic drug used to treat partial onset seizures in adults.
GlesatinibInvestigated for use/treatment in cancer/tumors (unspecified).
RanolazineAn anti-anginal drug used for the treatment of chronic angina.
Drugs & Drug Targets
DrugTargetType
Linezolid23S ribosomal RNAtarget
LinezolidAmine oxidase [flavin-containing] Aenzyme
LinezolidAmine oxidase [flavin-containing] Benzyme
LinezolidSerum albumincarrier
LinezolidSolute carrier family 22 member 6transporter
LinezolidSolute carrier family 22 member 8transporter
Benzylpenicilloyl polylysineHigh affinity immunoglobulin epsilon receptor subunit gammatarget
Benzylpenicilloyl polylysineHigh affinity immunoglobulin epsilon receptor subunit alphatarget
PhenacemideSodium channel protein type 1 subunit alphatarget
LevetiracetamSynaptic vesicle glycoprotein 2Atarget
LevetiracetamP-glycoprotein 1transporter
LevetiracetamVoltage-dependent N-type calcium channel subunit alpha-1Btarget
NepafenacProstaglandin G/H synthase 1target
NepafenacProstaglandin G/H synthase 2target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
EpanololCytochrome P450 2D6enzyme
Oseltamivir acidNeuraminidasetarget
OseltamivirNeuraminidasetarget
OseltamivirSialidase-1target
OseltamivirSialidase-2target
OseltamivirMultidrug resistance-associated protein 4transporter
OseltamivirSolute carrier family 15 member 1transporter
OseltamivirSolute carrier family 22 member 8transporter
OseltamivirLiver carboxylesterase 1enzyme
LacosamideSodium channel protein type 9 subunit alphatarget
LacosamideSodium channel protein type 3 subunit alphatarget
LacosamideSodium channel protein type 10 subunit alphatarget
LacosamideCytochrome P450 2C19enzyme
LacosamideCytochrome P450 2C9enzyme
LacosamideCytochrome P450 3A4enzyme
RanolazineCytochrome P450 3A4enzyme
RanolazineCytochrome P450 2D6enzyme
RanolazineBile salt export pumptransporter
RanolazineP-glycoprotein 1transporter
RanolazineSodium channel proteintarget
RanolazineInward rectifier potassium channeltarget
RanolazineVoltage gated L-type calcium channeltarget
RanolazineAlpha-1 adrenergic receptorstarget
RanolazineBeta-1 adrenergic receptortarget
RanolazineFatty acidtarget
RanolazineAlpha-1-acid glycoprotein 1carrier
RanolazineMultidrug and toxin extrusion protein 1transporter
RanolazineMultidrug and toxin extrusion protein 2transporter