- Accession Number
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
- ATC Classification
Drug Drug Description Phenylpropanolamine A sympathomimetic that was previously used in nasal decongestants and weight loss products, but has been withdrawn by the FDA due to safety risks and lack of efficacy. Amphetamine A CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Phentermine A sympathomimetic anorectic agent used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. Midodrine An alpha-adrenergic agonist used to treat orthostatic hypotension. Norepinephrine A sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest. Phenylephrine An alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics. Labetalol An alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Metaraminol For the treatment and prevention of hypotension due to hemorrhage, spinal anesthesia, and shock associated with brain damage Epinephrine A hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma. Methoxamine An alpha adrenergic agonist used to treat hypotension. Orciprenaline A beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD. Phenmetrazine Used as an anorectic in the treatment of obesity. Dobutamine A beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery. Benzphetamine A sympathomimetic used to manage exogenous obesity short term. Ritodrine An adrenergic beta agonist used to treat premature labor. Terbutaline A beta-2 adrenergic agonist used as a bronchodilator and to prevent premature labor. Oxymetazoline An alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea. Dopamine A catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension. Isoprenaline A catecholamine non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block. Acebutolol A selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults. Fenoterol A beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma. Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion. Mephentermine A sympathomimetic agent used in the treatment of hypotension. Procaterol A beta-2 adrenergic receptor agonist and bronchodilator used for the treatment of asthma and chronic obstructive pulmonary disease (COPD). Clenbuterol A decongestant and bronchodilator used in a variety of respiratory conditions. Chlorphentermine Used as an appetite suppressant. Metamfetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and exogenous obesity. Celiprolol A beta-blocker for the management of hypertension and angina pectoris. Nylidrin A vasodilator used to treat patients with peripheral vascular disorders, and elderly patients with symptoms associated with organic mental disorders. Tetryzoline An alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion. Tyramine Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An... Isoxsuprine A beta-adrenergic agonist used in the symptomatic treatment of cerebrovascular insufficiency, peripheral vascular disease of arteriosclerosis obliterans, thromboangiitis obliterans (Buerger's disease) and Raynaud's disease. Etilefrine An adrenergic agonist primarily of α1 and β1 receptors used as an anti-hypotensive. Synephrine Synephrine, also referred to as, p-synephrine, is naturally occurring alkaloid. It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer... Hydroxyamphetamine An indirectly acting sympathomimetic agent producing mydriasis for diagnostic purposes. Racepinephrine A bronchodilator used to treat intermittent asthma. Bucindolol Bucindolol has been investigated in Heart Failure. Tramazoline A sympathomimetic indicated for nasal decongestion. Fenozolone Not Annotated Tretoquinol Not Annotated Epanolol Epanolol is an beta blocker. Prenalterol Not Annotated Mefenorex Not Annotated Pseudoephedrine An alpha and beta adrenergic agonist used to treat nasal and sinus congestion, as well as allergic rhinitis. Diethylpropion An appetite suppressant used for the short term treatment of exogenous obesity in addition to calorie restriction. Lisdexamfetamine A central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) and moderate to severe eating disorders. Dextroamphetamine A sympathomimetic agent used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. MMDA MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present. Midomafetamine Clinical trials are now testing the therapeutic potential of MDMA for post-traumatic stress disorder (PTSD) and anxiety associated with terminal cancer. MDMA is one of the four most widely used... 2,5-Dimethoxy-4-ethylamphetamine Not Available 4-Bromo-2,5-dimethoxyamphetamine Not Available Tenamfetamine An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons... Iofetamine I-123 Not Annotated Ritobegron Ritobegron is under investigation in clinical trial NCT02256735 (Study to Investigate the Effect of KUC 7483 CL on the QT/QTc Interval of the ECG in Comparison to Placebo and Moxifloxacin... Mephedrone Mephedrone has been investigated in Alcohol-Related Disorders and Amphetamine-Related Disorders. Methoxyphenamine Not Annotated Gepefrine Not Annotated 2,5-Dimethoxy-4-ethylthioamphetamine 2,5-Dimethoxy-4-ethylthioamphetamine (ALEPH-2) is a phenylisopropylamine derivative with alleged anxiolytic and hallucinogenic properties. Methylenedioxyethamphetamine Not Available Phendimetrazine A sympathomimetic amine used as adjunct therapy for the short term management of exogenous obesity. Naphazoline A sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion. Levonordefrin A topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures. Hexamethylene diamine Not Available Famprofazone Famprofazone is a nonsteroidal anti-inflammatory agent found in combination products such as ‘Gewodin’ which is marketed in Taiwan. It is important to note that the drug is metabolized to methamphetamine...
- Drugs & Drug Targets