OCT1 substrates

Name
OCT1 substrates
Accession Number
DBCAT004550
Description

Substrates of the OCT1 transporter.

Drugs
DrugDrug Description
MetforminA biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS).
PhenforminFor the reatment of type II diabetes mellitus.
HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
CholineA nutrient found in a wide variety of vitamins including pre-natal formulations.
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
PancuroniumA neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
AcetylcholineA parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
SpermineFor nutritional supplementation, also for treating dietary shortage or imbalance
SpermidineSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and...
TubocurarineTubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
BuforminBuformin is an anti-diabetic drug of the biguanide class, chemically related to metformin and phenformin. It was withdrawn from the market in most countries due to a high risk of...
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
PramipexoleA non-ergot dopamine agonist used to treat the signs and symptoms of idiopathic Parkinson's disease and Restless Legs Syndrome (RLS).
AgmatineAgmatine is being studied experimentally for several indications such as cardioprotection, diabetes, decreased kidney function, neuroprotection (stroke, severe CNS injuries, epilepsy, glaucoma, and neuropathic pain), and psychiatric conditions (depression, anxiety,...
LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
NafamostatUsed as an anticoagulant in patients with disseminative blood vessel coagulation, hemorrhagic lesions, and hemorrhagic tendencies. It prevents blood clot formation during extracorporeal circulation in patients undergoing continuous renal replacement...
Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
GanciclovirA DNA polymerase inhibitor used to treat cytomegalovirus and herpetic keratitis of the eye.
AcyclovirA guanosine analog used to treat herpes simplex, varicella zoster, herpes zoster.
ThiamineA vitamin used to correct vitamin B1 deficiency.
RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
AmantadineA medication used to treat dyskinesia in Parkinson's patients receiving levodopa, as well as extrapyramidal side effects of medications.
VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
RocuroniumA vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.
Dexchlorpheniramine maleateA first generation antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema.
PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
CodeineAn opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated.
NintedanibA triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.
FormoterolAn inhaled long-acting beta2-adrenergic receptor agonist used as a bronchodilator in the management of asthma and COPD.
GuanfacineAn alpha-2A adrenergic receptor agonist used to treat ADHD.
SalmeterolA long-acting beta-2 adrenergic receptor agonist used to treat asthma and COPD.
LamotrigineA phenyltriazine antiepileptic used to treat some types of epilepsy and bipolar I disorder.
Drugs & Drug Targets
DrugTargetType
Metformin5'-AMP-activated protein kinase subunit beta-1target
MetforminSolute carrier family 22 member 2transporter
MetforminSolute carrier family 22 member 1transporter
MetforminMultidrug and toxin extrusion protein 1transporter
MetforminEquilibrative nucleoside transporter 4transporter
MetforminSolute carrier family 22 member 3transporter
MetforminMultidrug and toxin extrusion protein 2transporter
MetforminElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrialtarget
MetforminGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmictarget
Phenformin5'-AMP-activated protein kinase catalytic subunit alpha-1target
PhenforminCytochrome P450 2D6enzyme
PhenforminSolute carrier family 22 member 2transporter
PhenforminSolute carrier family 22 member 1transporter
PhenforminATP-sensitive inward rectifier potassium channel 8target
HistamineHistamine H1 receptortarget
HistamineHistamine H2 receptortarget
HistamineHistamine H3 receptortarget
HistamineHistamine N-methyltransferaseenzyme
HistamineSolute carrier family 22 member 2transporter
HistamineSolute carrier family 22 member 1transporter
HistamineSolute carrier family 22 member 3transporter
HistamineSolute carrier family 22 member 5transporter
HistamineHistamine H4 receptortarget
HistamineSynaptic vesicular amine transportertarget
DopamineDopamine D1 receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineSolute carrier family 22 member 5transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineDopamine D5 receptortarget
DopamineDopamine D2 receptortarget
DopamineDopamine D3 receptortarget
DopamineDopamine D4 receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
CholineCholine-phosphate cytidylyltransferase Btarget
CholineAcetylcholinesterasetarget
CholineCholine-phosphate cytidylyltransferase Atarget
CholinePhospholipase D2target
CholineCholinesterasetarget
CholinePhospholipase D1target
CholinePhosphoethanolamine/phosphocholine phosphatasetarget
CholineSolute carrier family 22 member 2transporter
CholineSolute carrier family 22 member 1transporter
CholineSolute carrier family 22 member 3transporter
CholineSolute carrier family 22 member 5transporter
CholineSolute carrier family 22 member 4transporter
CholineCholine/ethanolaminephosphotransferase 1enzyme
CholineCholine transporter-like protein 1transporter
CholineCholine transporter-like protein 4transporter
CholineCholine transporter-like protein 2transporter
CholineCholine transporter-like protein 3transporter
CholineCholine/ethanolamine kinaseenzyme
CholineCholine O-acetyltransferaseenzyme
CholineCholine kinase alphaenzyme
CholineCholine dehydrogenase, mitochondrialenzyme
CholineHigh affinity choline transporter 1transporter
CholineNeuronal acetylcholine receptor subunit alpha-7target
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
PancuroniumNeuronal acetylcholine receptor subunit alpha-2target
PancuroniumCholinesteraseenzyme
PancuroniumMuscarinic acetylcholine receptor M2target
PancuroniumMuscarinic acetylcholine receptor M3target
PancuroniumSolute carrier family 22 member 1transporter
PancuroniumSolute carrier family 22 member 2transporter
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
AcetylcholineAcetylcholinesterasetarget
AcetylcholineSolute carrier family 22 member 5transporter
AcetylcholineSolute carrier family 22 member 1transporter
AcetylcholineMuscarinic acetylcholine receptor M1target
AcetylcholineMuscarinic acetylcholine receptor M2target
AcetylcholineMuscarinic acetylcholine receptor M3target
AcetylcholineMuscarinic acetylcholine receptor M4target
AcetylcholineNeuronal acetylcholine receptor subunit alpha-7target
SpermineSpermine oxidasetarget
SpermineSpermine synthasetarget
SpermineOrnithine decarboxylasetarget
SpermineXanthine dehydrogenase/oxidaseenzyme
SpermineSolute carrier family 22 member 4transporter
SpermineSolute carrier family 22 member 1transporter
SpermineDNAtarget
SpermineDiamine acetyltransferase 1enzyme
SpermineDiamine acetyltransferase 2enzyme
SpermineExtracellular calcium-sensing receptortarget
SpermineBeta-1 adrenergic receptortarget
SpermineBeta-2 adrenergic receptortarget
SpermidineThioredoxin reductase 1, cytoplasmictarget
SpermidineGentamicin 3'-acetyltransferasetarget
SpermidineSpermidine/putrescine-binding periplasmic proteintarget
SpermidineSolute carrier family 22 member 4transporter
SpermidineSolute carrier family 22 member 1transporter
SpermidineBeta-1 adrenergic receptortarget
SpermidineBeta-2 adrenergic receptortarget
TubocurarineNeuronal acetylcholine receptor subunit alpha-2target
TubocurarineAcetylcholinesterasetarget
Tubocurarine5-hydroxytryptamine receptor 3Atarget
TubocurarineSolute carrier family 22 member 1transporter
TubocurarineSolute carrier family 22 member 2transporter
TubocurarineNeuronal acetylcholine receptor subunit alpha-7target
TubocurarineCholinesteraseenzyme
BuforminSolute carrier family 22 member 1transporter
CytarabineDNA polymerase betatarget
CytarabineCytidine deaminaseenzyme
CytarabineSolute carrier family 22 member 4transporter
CytarabineMultidrug resistance-associated protein 7transporter
CytarabineEquilibrative nucleoside transporter 1transporter
CytarabineDNAtarget
CytarabineCytochrome P450 3A4enzyme
CytarabineDeoxycytidine kinaseenzyme
Cytarabine5'-nucleotidaseenzyme
CytarabineDeoxycytidylate deaminaseenzyme
PramipexoleDopamine D3 receptortarget
PramipexoleDopamine D4 receptortarget
PramipexoleDopamine D2 receptortarget
Pramipexole5-hydroxytryptamine receptor 1Atarget
PramipexoleAlpha-2A adrenergic receptortarget
PramipexoleSolute carrier family 22 member 2transporter
PramipexoleSolute carrier family 22 member 1transporter
PramipexoleSolute carrier family 22 member 3transporter
AgmatineSolute carrier family 22 member 1transporter
AgmatineSolute carrier family 22 member 2transporter
AgmatineSolute carrier family 22 member 3transporter
AgmatineAlpha-2C adrenergic receptortarget
AgmatineNischarintarget
AgmatineAcetylcholine receptor subunit alphatarget
AgmatineGlutamate receptor ionotropic, NMDA 1target
AgmatineATP-sensitive inward rectifier potassium channel 1target
AgmatineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
AgmatineAcid-sensing ion channel 3target
AgmatineY+L amino acid transporter 1transporter
AgmatineCytochrome P450 3A4enzyme
LamivudineDNAtarget
LamivudineProtein Ptarget
LamivudineMultidrug resistance-associated protein 1transporter
LamivudineSolute carrier family 22 member 6transporter
LamivudineATP-binding cassette sub-family G member 2transporter
LamivudineReverse transcriptase/RNaseHtarget
LamivudineSolute carrier family 22 member 1transporter
LamivudineSolute carrier family 22 member 2transporter
LamivudineSolute carrier family 22 member 3transporter
LamivudineDeoxycytidine kinaseenzyme
LamivudineUMP-CMP kinaseenzyme
LamivudinePhosphoglycerate kinase 1enzyme
LamivudineNucleoside diphosphate kinase Aenzyme
LamivudineNucleoside diphosphate kinase Benzyme
LamivudineCholine-phosphate cytidylyltransferase Aenzyme
LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
LamivudineP-glycoprotein 1transporter
LamivudineMultidrug resistance-associated protein 4transporter
LamivudineCanalicular multispecific organic anion transporter 2transporter
LamivudineCanalicular multispecific organic anion transporter 1transporter
Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
LamivudineSerum albumincarrier
NafamostatIntercellular adhesion molecule 1target
NafamostatTrypsin-1target
NafamostatKallikrein-1target
NafamostatProthrombintarget
NafamostatCoagulation factor Xtarget
NafamostatCoagulation factor XIItarget
NafamostatSolute carrier family 22 member 1transporter
NafamostatSolute carrier family 22 member 2transporter
Choline salicylateCholine-phosphate cytidylyltransferase Btarget
Choline salicylateAcetylcholinesterasetarget
Choline salicylateCholine-phosphate cytidylyltransferase Atarget
Choline salicylatePhospholipase D2target
Choline salicylateCholinesterasetarget
Choline salicylatePhospholipase D1target
Choline salicylateSolute carrier family 22 member 2transporter
Choline salicylateSolute carrier family 22 member 1transporter
Choline salicylateSolute carrier family 22 member 3transporter
Choline salicylateSolute carrier family 22 member 5transporter
Choline salicylateSolute carrier family 22 member 4transporter
Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
Choline salicylateCholine transporter-like protein 1transporter
Choline salicylateCholine transporter-like protein 4transporter
Choline salicylateCholine transporter-like protein 3transporter
Choline salicylateCholine/ethanolamine kinaseenzyme
Choline salicylateCholine O-acetyltransferaseenzyme
Choline salicylateCholine kinase alphaenzyme
Choline salicylateCholine dehydrogenase, mitochondrialenzyme
Choline salicylateHigh affinity choline transporter 1transporter
Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
GanciclovirDNA polymerase catalytic subunittarget
GanciclovirThymidine kinasetarget
GanciclovirSolute carrier family 22 member 1transporter
GanciclovirSolute carrier family 22 member 6transporter
GanciclovirSolute carrier family 22 member 8transporter
GanciclovirSolute carrier family 22 member 7transporter
GanciclovirDNAtarget
GanciclovirMultidrug and toxin extrusion protein 1transporter
GanciclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirDNA polymerase catalytic subunittarget
AcyclovirThymidine kinasetarget
AcyclovirSolute carrier family 22 member 1transporter
AcyclovirSolute carrier family 22 member 6transporter
AcyclovirSolute carrier family 22 member 8transporter
AcyclovirIleal sodium/bile acid cotransportertransporter
AcyclovirMultidrug and toxin extrusion protein 1transporter
AcyclovirMultidrug and toxin extrusion protein 2transporter
AcyclovirThymidine kinaseenzyme
AcyclovirGuanylate kinaseenzyme
AcyclovirNucleoside diphosphokinaseenzyme
AcyclovirPyruvate Kinasesenzyme
AcyclovirCreatine Kinasesenzyme
AcyclovirPhosphoglycerate Kinasesenzyme
AcyclovirSuccinyl-CoA Synthetasesenzyme
AcyclovirPhosphoenolpyruvate Carboxykinasesenzyme
AcyclovirAdenylosuccinate Synthetasesenzyme
AcyclovirSerum albumincarrier
ThiamineThiamin pyrophosphokinase 1target
ThiamineSolute carrier family 22 member 2transporter
ThiamineSolute carrier family 22 member 1transporter
ThiamineSolute carrier family 22 member 5transporter
ThiamineCytochrome P450 4B1enzyme
ThiamineThiamine transporter 1transporter
ThiamineThiamine transporter 2transporter
ThiamineThiamin pyrophosphokinase 1enzyme
ThiamineEctonucleoside triphosphate diphosphohydrolase 5enzyme
ThiamineThiamine-triphosphataseenzyme
ThiamineSerum albumincarrier
RanitidineHistamine H2 receptortarget
RanitidineCytochrome P450 1A2enzyme
RanitidineCytochrome P450 2D6enzyme
RanitidineSolute carrier family 22 member 1transporter
RanitidineP-glycoprotein 1transporter
RanitidineSolute carrier family 22 member 8transporter
RanitidineCytochrome P450 3A4enzyme
RanitidineAcetylcholinesterasetarget
RanitidineSolute carrier family 22 member 2transporter
RanitidineAcetylcholinesteraseenzyme
AmantadineDopamine D2 receptortarget
AmantadineMatrix protein 2target
AmantadineAromatic-L-amino-acid decarboxylaseenzyme
AmantadineAmine oxidase [flavin-containing] Benzyme
AmantadineSolute carrier family 22 member 2transporter
AmantadineSolute carrier family 22 member 1transporter
AmantadineGlutamate receptor ionotropic, NMDA 3Atarget
AmantadineNeuronal acetylcholine receptor subunit alpha-7target
AmantadineNeuronal acetylcholine receptor subunit alpha-4target
AmantadineNeuronal acetylcholine receptor subunit alpha-3target
VerapamilATP-sensitive inward rectifier potassium channel 11target
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
VerapamilPotassium voltage-gated channel subfamily H member 2target
VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
VerapamilCytochrome P450 1A2enzyme
VerapamilCytochrome P450 3A5enzyme
VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
VerapamilSodium-dependent serotonin transportertarget
VerapamilCytochrome P450 3A4enzyme
VerapamilP-glycoprotein 1transporter
VerapamilSolute carrier family 22 member 1transporter
VerapamilCanalicular multispecific organic anion transporter 2transporter
VerapamilMultidrug resistance-associated protein 4transporter
VerapamilSolute carrier family 22 member 5transporter
VerapamilSolute carrier organic anion transporter family member 1A2transporter
VerapamilMultidrug resistance-associated protein 7transporter
VerapamilSolute carrier family 22 member 4transporter
VerapamilSolute carrier organic anion transporter family member 1B1transporter
VerapamilCytochrome P450 2C8enzyme
VerapamilCytochrome P450 2C9enzyme
VerapamilCytochrome P450 2B6enzyme
VerapamilCytochrome P450 2C19enzyme
VerapamilCytochrome P450 2D6enzyme
VerapamilAlpha-1A adrenergic receptortarget
VerapamilAlpha-1B adrenergic receptortarget
VerapamilAlpha-1D adrenergic receptortarget
VerapamilSerum albumincarrier
VerapamilAlpha-1-acid glycoprotein 1carrier
VerapamilCytochrome P450 2C18enzyme
VerapamilCytochrome P450 2E1enzyme
VerapamilMultidrug resistance-associated protein 1transporter
VerapamilMultidrug and toxin extrusion protein 1transporter
VerapamilMultidrug and toxin extrusion protein 2transporter
VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
RocuroniumNeuronal acetylcholine receptor subunit alpha-2target
RocuroniumMuscarinic acetylcholine receptor M2target
Rocuronium5-hydroxytryptamine receptor 3Atarget
RocuroniumSolute carrier family 22 member 1transporter
RocuroniumSolute carrier organic anion transporter family member 1A2transporter
Dexchlorpheniramine maleateCytochrome P450 2D6enzyme
Dexchlorpheniramine maleateHistamine H1 receptortarget
Dexchlorpheniramine maleateSolute carrier family 22 member 1carrier
Dexchlorpheniramine maleateSolute carrier family 22 member 2carrier
Dexchlorpheniramine maleateCytochrome P450 3A4enzyme
PrazosinAlpha-1A adrenergic receptortarget
PrazosinAlpha-1B adrenergic receptortarget
PrazosinAlpha-1D adrenergic receptortarget
PrazosinPotassium voltage-gated channel subfamily H member 2target
PrazosinAlpha-1-acid glycoprotein 1carrier
PrazosinSolute carrier family 22 member 1transporter
PrazosinSolute carrier family 22 member 3transporter
PrazosinP-glycoprotein 1transporter
PrazosinATP-binding cassette sub-family G member 2transporter
PrazosinAlpha-2A adrenergic receptortarget
PrazosinAlpha-2B adrenergic receptortarget
PrazosinAlpha-1 adrenergic receptorstarget
CodeineMu-type opioid receptortarget
CodeineDelta-type opioid receptortarget
CodeineKappa-type opioid receptortarget
CodeineCytochrome P450 2D6enzyme
CodeineCytochrome P450 3A4enzyme
CodeineSolute carrier family 22 member 1transporter
CodeineUDP-glucuronosyltransferase 2B7enzyme
CodeineUDP-glucuronosyltransferase 2B4enzyme
NintedanibVascular endothelial growth factor receptor 1target
NintedanibVascular endothelial growth factor receptor 2target
NintedanibVascular endothelial growth factor receptor 3target
NintedanibPlatelet-derived growth factor receptor alphatarget
NintedanibPlatelet-derived growth factor receptor betatarget
NintedanibFibroblast growth factor receptor 1target
NintedanibFibroblast growth factor receptor 2target
NintedanibFibroblast growth factor receptor 3target
NintedanibReceptor-type tyrosine-protein kinase FLT3target
NintedanibTyrosine-protein kinase Lcktarget
NintedanibTyrosine-protein kinase Lyntarget
NintedanibProto-oncogene tyrosine-protein kinase Srctarget
NintedanibP-glycoprotein 1transporter
NintedanibCytochrome P450 3A4enzyme
NintedanibSolute carrier family 22 member 1transporter
NintedanibSerum albumincarrier
NintedanibUDP-glucuronosyltransferase 1-1enzyme
NintedanibUDP-glucuronosyltransferase 1-7enzyme
NintedanibUDP-glucuronosyltransferase 1-8enzyme
NintedanibUDP-glucuronosyltransferase 1-10enzyme
NintedanibATP-binding cassette sub-family G member 2transporter
FormoterolBeta-2 adrenergic receptortarget
FormoterolBeta-1 adrenergic receptortarget
FormoterolBeta-3 adrenergic receptortarget
FormoterolCytochrome P450 2D6enzyme
FormoterolCytochrome P450 2C19enzyme
FormoterolCytochrome P450 2C9enzyme
FormoterolCytochrome P450 2A6enzyme
FormoterolUDP-glucuronosyltransferase 1A1enzyme
FormoterolUDP-glucuronosyltransferase 1-8enzyme
FormoterolUDP-glucuronosyltransferase 1-9enzyme
FormoterolUDP-glucuronosyltransferase 2B7enzyme
FormoterolUDP-glucuronosyltransferase 2B15enzyme
FormoterolSolute carrier family 22 member 1transporter
FormoterolSolute carrier family 22 member 4transporter
FormoterolSolute carrier family 22 member 5transporter
FormoterolSolute carrier family 22 member 3transporter
FormoterolSerum albumincarrier
GuanfacineAlpha-2A adrenergic receptortarget
GuanfacineCytochrome P450 2C19enzyme
GuanfacineCytochrome P450 3A4enzyme
GuanfacineAlpha-2B adrenergic receptortarget
GuanfacineMultidrug and toxin extrusion protein 1transporter
GuanfacineSolute carrier family 22 member 1transporter
GuanfacineSolute carrier family 22 member 2transporter
SalmeterolBeta-2 adrenergic receptortarget
SalmeterolCytochrome P450 3A4enzyme
SalmeterolCytochrome P450 2C8enzyme
SalmeterolCytochrome P450 3A5enzyme
SalmeterolCytochrome P450 3A7enzyme
SalmeterolBeta-1 adrenergic receptortarget
SalmeterolBeta-3 adrenergic receptortarget
SalmeterolSerum albumincarrier
Salmeterolalpha1-acid glycoproteincarrier
SalmeterolSolute carrier family 22 member 1transporter
SalmeterolSolute carrier family 22 member 2transporter
SalmeterolSolute carrier family 22 member 3transporter
LamotrigineVoltage-gated sodium channel alpha subunittarget
LamotrigineUDP-glucuronosyltransferases (UGTs)enzyme
LamotrigineP-glycoprotein 1transporter
LamotrigineDihydrofolate reductaseenzyme
Lamotrigine5-hydroxytryptamine receptor 3Atarget
LamotrigineVoltage-dependent R-type calcium channel subunit alpha-1E (CACNA1E)target
LamotrigineAdenosine receptor A1target
LamotrigineAdenosine receptor A2atarget
LamotrigineAlpha-1A adrenergic receptortarget
LamotrigineAlpha-2A adrenergic receptortarget
LamotrigineBeta-1 adrenergic receptortarget
LamotrigineD(1) dopamine receptortarget
LamotrigineDopamine D2 receptortarget
LamotrigineGABA(A) Receptortarget
LamotrigineGABA(A) Receptor Benzodiazepine Binding Sitetarget
LamotrigineHistamine H1 receptortarget
LamotrigineKappa-type opioid receptortarget
LamotrigineAcetylcholine receptor subunit alphatarget
Lamotrigine5-hydroxytryptamine receptor 2Atarget
LamotrigineSolute carrier family 22 member 2transporter
LamotrigineSerum albumincarrier
LamotrigineSolute carrier family 22 member 1transporter
LamotrigineGlutamate receptor 1target