Biguanides

DBCAT000761Therapeutic categoryP01BB

Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES. A DrugBank category of 9 drugs. 8 of them are approved.

ATC classification: P — ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS
P01 — ANTIPROTOZOALS
P01B — ANTIMALARIALS
P01BB — Biguanides
Drugs: Atovaquone
Buformin
Chlorhexidine
Chloroquine
Chlorproguanil
Cycloguanil
Metformin
Phenformin
Proguanil

What you can answer from here — as of September 15, 2022

9DrugsEach linked to its full drug card

Listed above

24Drug targetsEvery drug–target pair in the class, with bond type

5,924Marketed productsAcross the regions we cover, with dosage forms and routes

27Routes of administrationHow the drugs in this class are given

Which targets do Biguanides share, and which companies have late-stage candidates in this class?

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